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The map label for this gene is fabR [H]

Identifier: 119945227

GI number: 119945227

Start: 1840552

End: 1841160

Strand: Reverse

Name: fabR [H]

Synonym: Ping_1493

Alternate gene names: 119945227

Gene position: 1841160-1840552 (Counterclockwise)

Preceding gene: 119945232

Following gene: 119945219

Centisome position: 40.38

GC content: 39.74

Gene sequence:

>609_bases
ATGAGTAGCATTAGAGCACAGCAAAAAGAAAAAACCCGCCGTCTGTTAATTGATGCAGCTTTCGCTCAATTAAGTGCTGA
ACGCAGTTTTTCAAATTTAAGTTTACGAGAAGTGACTAAAGCGGCAGGACTCTCACCAAACTCATTTTATCGTCATTTTT
CAGATATGGAAGAGCTTGGTTTGATCTTGATTAACGAAGTAGGCTTAGTGCTTAAGCAACTAAGGTCTCAAGCCAGACTG
CGCATTAAAAAAGGCGGTTCAGCCGTAAAAATATCCGTGTTGACTTTTATGGAGTTCATTGAACAATACGCTAATATTTT
TCGCTTGTTATTACAGGAAAGAGCCGGTGCCTCAACAGCATTTAGAACTGCACTGAGCCGTGAAATAGATTCTTTTACTA
TGGTACTTTGCGGTTATTTACAGCAAGCTAACAAGTTAAATGCCGAGTCGGCTTATCTGCAAGCCAACGCAACGATCATC
ATTGTTTTTAGTGCGGGTGCAGAGGCCTTAGATGTTGACCAAAAAAGACGGGATGATTTAACTAAACGTACTATTTTACA
GTTACAAATGATTGACAAAGGATCATTAGAGATGAACTTATCCCGGTAG

Upstream 100 bases:

>100_bases
CAATCTCTGCACATTGCTTGCTAAAGTCATACATTGGGAATACCCATACGCTTCGGAATGCTATCGGAATAAATAACGGT
TTTTATGAAAAGGTCTGGTC

Downstream 100 bases:

>100_bases
ATTGAGCTGCTGGTTGCGAGCTTCGAGCCTTCGAGCCTGCGGGCTGTGACAGTATCGAAAGATCAACAGGTTGGTAAATC
AACGTGCTTGAAATATAGGC

Product: DNA-binding transcriptional repressor FabR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MSSIRAQQKEKTRRLLIDAAFAQLSAERSFSNLSLREVTKAAGLSPNSFYRHFSDMEELGLILINEVGLVLKQLRSQARL
RIKKGGSAVKISVLTFMEFIEQYANIFRLLLQERAGASTAFRTALSREIDSFTMVLCGYLQQANKLNAESAYLQANATII
IVFSAGAEALDVDQKRRDDLTKRTILQLQMIDKGSLEMNLSR

Sequences:

>Translated_202_residues
MSSIRAQQKEKTRRLLIDAAFAQLSAERSFSNLSLREVTKAAGLSPNSFYRHFSDMEELGLILINEVGLVLKQLRSQARL
RIKKGGSAVKISVLTFMEFIEQYANIFRLLLQERAGASTAFRTALSREIDSFTMVLCGYLQQANKLNAESAYLQANATII
IVFSAGAEALDVDQKRRDDLTKRTILQLQMIDKGSLEMNLSR
>Mature_201_residues
SSIRAQQKEKTRRLLIDAAFAQLSAERSFSNLSLREVTKAAGLSPNSFYRHFSDMEELGLILINEVGLVLKQLRSQARLR
IKKGGSAVKISVLTFMEFIEQYANIFRLLLQERAGASTAFRTALSREIDSFTMVLCGYLQQANKLNAESAYLQANATIII
VFSAGAEALDVDQKRRDDLTKRTILQLQMIDKGSLEMNLSR

Specific function: Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, fabR directly influences the physical properties of the membrane bilayer [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693209, Length=192, Percent_Identity=58.3333333333333, Blast_Score=223, Evalue=7e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22698; Mature: 22566

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSIRAQQKEKTRRLLIDAAFAQLSAERSFSNLSLREVTKAAGLSPNSFYRHFSDMEELG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
LILINEVGLVLKQLRSQARLRIKKGGSAVKISVLTFMEFIEQYANIFRLLLQERAGASTA
HHHHHHHHHHHHHHHHHHHEEHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
FRTALSREIDSFTMVLCGYLQQANKLNAESAYLQANATIIIVFSAGAEALDVDQKRRDDL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEECCCEEEEEECCCCCHHCCCHHHHHHH
TKRTILQLQMIDKGSLEMNLSR
HHHHHHHHHCCCCCCCEEECCC
>Mature Secondary Structure 
SSIRAQQKEKTRRLLIDAAFAQLSAERSFSNLSLREVTKAAGLSPNSFYRHFSDMEELG
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
LILINEVGLVLKQLRSQARLRIKKGGSAVKISVLTFMEFIEQYANIFRLLLQERAGASTA
HHHHHHHHHHHHHHHHHHHEEHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
FRTALSREIDSFTMVLCGYLQQANKLNAESAYLQANATIIIVFSAGAEALDVDQKRRDDL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEECCCEEEEEECCCCCHHCCCHHHHHHH
TKRTILQLQMIDKGSLEMNLSR
HHHHHHHHHCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA