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The map label for this gene is ppiD [H]

Identifier: 119945205

GI number: 119945205

Start: 1815513

End: 1817408

Strand: Direct

Name: ppiD [H]

Synonym: Ping_1469

Alternate gene names: 119945205

Gene position: 1815513-1817408 (Clockwise)

Preceding gene: 119945204

Following gene: 119945209

Centisome position: 39.82

GC content: 40.3

Gene sequence:

>1896_bases
ATGTTAGATAAAATGCGCGAAGGCGCACAAGGTGCCACGGCTAAAATTATAATCGTTGTGATAATTTTATCATTCGCCCT
AGCGGGAGTGAGTAGTTATTTAGGCGGTAGCGGTATTTCCGTTGCTGTTACTGTGAATGATGAAGAAATAAGTAAAGCGA
CAGTTGATCAAGCTTATCAAAATGAGCGTACTCGTTTAGAGCAGCAATATGGCGAACAGTTTGCACTGCTGGCATCAACT
CCTAATTTCAACCAAAAAATTAGACAGCAAGCGATGCAAACGGTTATTTCAGAGCGTCTTCTTACGCAAGCCATTAAGGA
TATGGGATTGCGTATTGGTGATGAGCAAGTTAAACAAGAAATTCGTAAAATGAAAGAGTTTCAAGTTGATGGAAACTTTA
ATAACGAACAATATTTATCATTATTAAGACGAGCGAGTTATACACCGGCGCAATTTAGTCAAAGTATAAAACAGGATCTC
GCACGTCGTCAGTTGCTTACTATGGTACTTGGTAGTGAATTTATCTTACCGATGGAAGTGCAGCAAGCTAATCGCTTACA
AGCTCAAAAACGTGTGGCAAGAGTGCTAACGGTTAAAGCGAGTGATTTTGCTGATAAAGATCCCATCAGTGAACAAGAAA
TATCGACTTATTACGAAAACAACAGCCAGTTTTTTCAAACAGCTGAGCAAGTCAGTGTCGATTATGTTGTCTTAGATGGT
TCATTGTTAGCTGACCGGGTGACCTTAAGCAGTGAAGAGCTGGAAAAATATTACGACATGCACGCATCTGATTATCAGCG
TGGTGAAAAGCGCAAAGTTGCGCATATCTTACTGCTCGGAGACAACAGTGCGGCAAAAGAAAAAGCGCAAGCTATTTTGT
CTGAACTTGAAGAGGGGGCTGATTTTGCACAACTTGCCGCTCAAAAATCAGAGGATAGCTATTCTGCTGAAAATAATGGT
GAATTGGACTGGTTTGAACGTGGTGTAATGGATCCTGCATTTGATGACGCTGCATTTAAGCTCACCAAAGAAGCGCCTTT
GTCGAATATTGTTAAATCACAATTTGGTTATCACATCATCAAATTAGTTGATATTCAAGAAAGTAAGAAATTACCTTTGT
CCGAGGTGACAGCGCAAGTTGAGAACGCCGCCAAACGGGAAGAAATGAATAATCTTTATTATGAGCTGCATCAAAGGTTA
AGTGAAGCCGCCTTTGAAAGACCTGATAATTTAGATGAAGCTGCTAGAGTGCTTGGCACAGATATTCAACATACAGAACT
GTTTTCAGCTGCAGAGGCGCCCGAACCGCTTACAGATAATGCGGTTTTAAAAATCGTATTTGATAGCGCATTTCGTGAAG
ATAGAATGAACTCAGAGCTTATTGAGCTTTCTGAAAATAAAGTGATTGTTGTCCATGTTAATCGTTATCAAGCGGCGGCA
TTACAACCACTTGCTGACGTTTCTGAGCAGATTATAGCGCAGCTACAGGCACAGAAAGCGCATAAAAACACAGAAGAGTT
TGTTAAGTCGTTAATGGTCAAGTTGAAGGCACAAGAGTCGATTGAAACTATCTTGACTGAGAAAAATTTGGCATTCAGTG
ACCCGTCAACCTTTACACGTAATGACAGTGAGCTTGATTATCGTGTGATGCAGGCGGTCTTTAAATTAGCTAAACCAACG
GAGCAGCAAGCGACCTACGATTGGGTGACCACAAGTACAGATGATTATGCGTTAATTGAGCTAACGTCTGTTGAAGAACT
TGATTCTGAGTTGAAAAACGTTGATAAGATACAAAAACTTGAAGAGAGGTTGCAACGCTTATTTTCAGAATCAACCTATC
AAGCCTTATCAATGGCGTTAATGGCTAATGCAGATATTAAATATCCTGCTGAATAA

Upstream 100 bases:

>100_bases
CTGAAGCGCTTTAGTTGCTTATACGGCGATTAACGGCAGAATATTATCAATTAAGTTGCCATTAAAAAATTGGTCTAAGT
TTTTAAGAGAAGACAAAGTT

Downstream 100 bases:

>100_bases
TTAGATTATTTGCTAAAAAACTAAAAAGGCGACTATATTTAGTCGCCTTTTTTATGGCAGAAATAACAGTGGGATGTCAA
AAAAAGGGGGGAGCCAATTT

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 631; Mature: 631

Protein sequence:

>631_residues
MLDKMREGAQGATAKIIIVVIILSFALAGVSSYLGGSGISVAVTVNDEEISKATVDQAYQNERTRLEQQYGEQFALLAST
PNFNQKIRQQAMQTVISERLLTQAIKDMGLRIGDEQVKQEIRKMKEFQVDGNFNNEQYLSLLRRASYTPAQFSQSIKQDL
ARRQLLTMVLGSEFILPMEVQQANRLQAQKRVARVLTVKASDFADKDPISEQEISTYYENNSQFFQTAEQVSVDYVVLDG
SLLADRVTLSSEELEKYYDMHASDYQRGEKRKVAHILLLGDNSAAKEKAQAILSELEEGADFAQLAAQKSEDSYSAENNG
ELDWFERGVMDPAFDDAAFKLTKEAPLSNIVKSQFGYHIIKLVDIQESKKLPLSEVTAQVENAAKREEMNNLYYELHQRL
SEAAFERPDNLDEAARVLGTDIQHTELFSAAEAPEPLTDNAVLKIVFDSAFREDRMNSELIELSENKVIVVHVNRYQAAA
LQPLADVSEQIIAQLQAQKAHKNTEEFVKSLMVKLKAQESIETILTEKNLAFSDPSTFTRNDSELDYRVMQAVFKLAKPT
EQQATYDWVTTSTDDYALIELTSVEELDSELKNVDKIQKLEERLQRLFSESTYQALSMALMANADIKYPAE

Sequences:

>Translated_631_residues
MLDKMREGAQGATAKIIIVVIILSFALAGVSSYLGGSGISVAVTVNDEEISKATVDQAYQNERTRLEQQYGEQFALLAST
PNFNQKIRQQAMQTVISERLLTQAIKDMGLRIGDEQVKQEIRKMKEFQVDGNFNNEQYLSLLRRASYTPAQFSQSIKQDL
ARRQLLTMVLGSEFILPMEVQQANRLQAQKRVARVLTVKASDFADKDPISEQEISTYYENNSQFFQTAEQVSVDYVVLDG
SLLADRVTLSSEELEKYYDMHASDYQRGEKRKVAHILLLGDNSAAKEKAQAILSELEEGADFAQLAAQKSEDSYSAENNG
ELDWFERGVMDPAFDDAAFKLTKEAPLSNIVKSQFGYHIIKLVDIQESKKLPLSEVTAQVENAAKREEMNNLYYELHQRL
SEAAFERPDNLDEAARVLGTDIQHTELFSAAEAPEPLTDNAVLKIVFDSAFREDRMNSELIELSENKVIVVHVNRYQAAA
LQPLADVSEQIIAQLQAQKAHKNTEEFVKSLMVKLKAQESIETILTEKNLAFSDPSTFTRNDSELDYRVMQAVFKLAKPT
EQQATYDWVTTSTDDYALIELTSVEELDSELKNVDKIQKLEERLQRLFSESTYQALSMALMANADIKYPAE
>Mature_631_residues
MLDKMREGAQGATAKIIIVVIILSFALAGVSSYLGGSGISVAVTVNDEEISKATVDQAYQNERTRLEQQYGEQFALLAST
PNFNQKIRQQAMQTVISERLLTQAIKDMGLRIGDEQVKQEIRKMKEFQVDGNFNNEQYLSLLRRASYTPAQFSQSIKQDL
ARRQLLTMVLGSEFILPMEVQQANRLQAQKRVARVLTVKASDFADKDPISEQEISTYYENNSQFFQTAEQVSVDYVVLDG
SLLADRVTLSSEELEKYYDMHASDYQRGEKRKVAHILLLGDNSAAKEKAQAILSELEEGADFAQLAAQKSEDSYSAENNG
ELDWFERGVMDPAFDDAAFKLTKEAPLSNIVKSQFGYHIIKLVDIQESKKLPLSEVTAQVENAAKREEMNNLYYELHQRL
SEAAFERPDNLDEAARVLGTDIQHTELFSAAEAPEPLTDNAVLKIVFDSAFREDRMNSELIELSENKVIVVHVNRYQAAA
LQPLADVSEQIIAQLQAQKAHKNTEEFVKSLMVKLKAQESIETILTEKNLAFSDPSTFTRNDSELDYRVMQAVFKLAKPT
EQQATYDWVTTSTDDYALIELTSVEELDSELKNVDKIQKLEERLQRLFSESTYQALSMALMANADIKYPAE

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=590, Percent_Identity=33.728813559322, Blast_Score=337, Evalue=1e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 71232; Mature: 71232

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS00165 DEHYDRATASE_SER_THR ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDKMREGAQGATAKIIIVVIILSFALAGVSSYLGGSGISVAVTVNDEEISKATVDQAYQ
CCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHH
NERTRLEQQYGEQFALLASTPNFNQKIRQQAMQTVISERLLTQAIKDMGLRIGDEQVKQE
HHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
IRKMKEFQVDGNFNNEQYLSLLRRASYTPAQFSQSIKQDLARRQLLTMVLGSEFILPMEV
HHHHHHEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
QQANRLQAQKRVARVLTVKASDFADKDPISEQEISTYYENNSQFFQTAEQVSVDYVVLDG
HHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCEEEEEECC
SLLADRVTLSSEELEKYYDMHASDYQRGEKRKVAHILLLGDNSAAKEKAQAILSELEEGA
HHHHHHHHCCHHHHHHHHHCCCHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCC
DFAQLAAQKSEDSYSAENNGELDWFERGVMDPAFDDAAFKLTKEAPLSNIVKSQFGYHII
HHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHCCCEEE
KLVDIQESKKLPLSEVTAQVENAAKREEMNNLYYELHQRLSEAAFERPDNLDEAARVLGT
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
DIQHTELFSAAEAPEPLTDNAVLKIVFDSAFREDRMNSELIELSENKVIVVHVNRYQAAA
CCHHHHHHHHHCCCCCCCCCHHEEHHHHHHHHHHCCCCHHHHCCCCCEEEEEECCHHHHH
LQPLADVSEQIIAQLQAQKAHKNTEEFVKSLMVKLKAQESIETILTEKNLAFSDPSTFTR
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
NDSELDYRVMQAVFKLAKPTEQQATYDWVTTSTDDYALIELTSVEELDSELKNVDKIQKL
CCCHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHH
EERLQRLFSESTYQALSMALMANADIKYPAE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLDKMREGAQGATAKIIIVVIILSFALAGVSSYLGGSGISVAVTVNDEEISKATVDQAYQ
CCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHH
NERTRLEQQYGEQFALLASTPNFNQKIRQQAMQTVISERLLTQAIKDMGLRIGDEQVKQE
HHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
IRKMKEFQVDGNFNNEQYLSLLRRASYTPAQFSQSIKQDLARRQLLTMVLGSEFILPMEV
HHHHHHEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
QQANRLQAQKRVARVLTVKASDFADKDPISEQEISTYYENNSQFFQTAEQVSVDYVVLDG
HHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCEEEEEECC
SLLADRVTLSSEELEKYYDMHASDYQRGEKRKVAHILLLGDNSAAKEKAQAILSELEEGA
HHHHHHHHCCHHHHHHHHHCCCHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCC
DFAQLAAQKSEDSYSAENNGELDWFERGVMDPAFDDAAFKLTKEAPLSNIVKSQFGYHII
HHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHCCCEEE
KLVDIQESKKLPLSEVTAQVENAAKREEMNNLYYELHQRLSEAAFERPDNLDEAARVLGT
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
DIQHTELFSAAEAPEPLTDNAVLKIVFDSAFREDRMNSELIELSENKVIVVHVNRYQAAA
CCHHHHHHHHHCCCCCCCCCHHEEHHHHHHHHHHCCCCHHHHCCCCCEEEEEECCHHHHH
LQPLADVSEQIIAQLQAQKAHKNTEEFVKSLMVKLKAQESIETILTEKNLAFSDPSTFTR
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
NDSELDYRVMQAVFKLAKPTEQQATYDWVTTSTDDYALIELTSVEELDSELKNVDKIQKL
CCCHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHH
EERLQRLFSESTYQALSMALMANADIKYPAE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]