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The map label for this gene is add [H]

Identifier: 119945191

GI number: 119945191

Start: 1794451

End: 1795452

Strand: Direct

Name: add [H]

Synonym: Ping_1455

Alternate gene names: 119945191

Gene position: 1794451-1795452 (Clockwise)

Preceding gene: 119945188

Following gene: 119945192

Centisome position: 39.36

GC content: 43.01

Gene sequence:

>1002_bases
ATGATTACTAACACGCTCCCATTAACAGATCTTCACCGTCATCTTGATGGTAATATCCGCATAGAAACCATTTTAGAATT
AGGTCAAAAATTTGCCTTACCTTTGCCCGCTTATGATATTGAGGGCTTACGTCCCTATGTGCAAGTTGTTGAAAATGAAG
CAGATTTAATGGCTTTTTTATCTAAATTGGATTGGGGTGTCGCGGTGTTGGGCGATCTTGATGCTTGTCGCCGTATTGCC
TATGAAAATGTGCAGGATGTGATGCATGCAAAAATTGATTATGCGGAGTTGCGCTTTTCACCTTATTACATGGCAATGAA
ACACAATTTACCGCTTGCTGGTGTTGTTGAGGCTGTTGTGGACGGTGTGCATGCGGGGTGTCGCGATTTCTCTGTTAAAG
CCAATTTAATCGGCATTATGAGCCGTACTTTCGGCAAGCAACGCTGCCAACAAGAGCTTGCTGCTTTATTAACTCAAAAA
GATAAATTAGTTGCAATTGATTTGGCTGGCGATGAATTGGGGCACCCCGGCGAGCATTTTGTCGAACATTTTAAAACAGT
TCGAAATGCAAATTTACAGGTCACTGTGCATGCCGGAGAGGCAGCTGGTGCAAGCAGTATTTGGCAGGCAATTAATAAGC
TTGGAGCAACCCGCATTGGGCACGGTGTGAAAGCGATTGAAGATCCGACATTATTGGATTATCTGGTTAAACATAAAATA
GGGATCGAATCTTGTTTAACCTCAAATAGTCAAACAAGCACGGTGAGCTCCTTTGCAAAGCATCCTATAAAGACTTTTTT
AGCGCACGGGGTGCTCGCGTGTTTAAACAGTGATGATCCCGCTGTTGAAGGGATTGAACTCGCGCATGAATATCAAGTGG
CGGCAACAAAAGTCGGTTTAAATCAAGACCAAATTCGTCAAGCACAAATTAATGGTCTTGAAGTTGCGTTTCTATCTGAT
GCCGAAAAAGCAGCACTGCGTAACGATGCATTAAATCGTTAG

Upstream 100 bases:

>100_bases
GCGTAATTAGAATAGCTAGTTACTGCAATCAATGCCTTGCTTTTATGCGTTTTTTCTGCGCCTAAAGAGATCACTAAATT
AACGGAATTGGTACTAAATA

Downstream 100 bases:

>100_bases
CTATTTATCCACGCGGTGCAATATCTGATTAATTCCTTTACTATCAATTCCCTTCAAAATATATATTCAAGGGGATTGCA
TATATTAATCATTAGAAAAA

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MITNTLPLTDLHRHLDGNIRIETILELGQKFALPLPAYDIEGLRPYVQVVENEADLMAFLSKLDWGVAVLGDLDACRRIA
YENVQDVMHAKIDYAELRFSPYYMAMKHNLPLAGVVEAVVDGVHAGCRDFSVKANLIGIMSRTFGKQRCQQELAALLTQK
DKLVAIDLAGDELGHPGEHFVEHFKTVRNANLQVTVHAGEAAGASSIWQAINKLGATRIGHGVKAIEDPTLLDYLVKHKI
GIESCLTSNSQTSTVSSFAKHPIKTFLAHGVLACLNSDDPAVEGIELAHEYQVAATKVGLNQDQIRQAQINGLEVAFLSD
AEKAALRNDALNR

Sequences:

>Translated_333_residues
MITNTLPLTDLHRHLDGNIRIETILELGQKFALPLPAYDIEGLRPYVQVVENEADLMAFLSKLDWGVAVLGDLDACRRIA
YENVQDVMHAKIDYAELRFSPYYMAMKHNLPLAGVVEAVVDGVHAGCRDFSVKANLIGIMSRTFGKQRCQQELAALLTQK
DKLVAIDLAGDELGHPGEHFVEHFKTVRNANLQVTVHAGEAAGASSIWQAINKLGATRIGHGVKAIEDPTLLDYLVKHKI
GIESCLTSNSQTSTVSSFAKHPIKTFLAHGVLACLNSDDPAVEGIELAHEYQVAATKVGLNQDQIRQAQINGLEVAFLSD
AEKAALRNDALNR
>Mature_333_residues
MITNTLPLTDLHRHLDGNIRIETILELGQKFALPLPAYDIEGLRPYVQVVENEADLMAFLSKLDWGVAVLGDLDACRRIA
YENVQDVMHAKIDYAELRFSPYYMAMKHNLPLAGVVEAVVDGVHAGCRDFSVKANLIGIMSRTFGKQRCQQELAALLTQK
DKLVAIDLAGDELGHPGEHFVEHFKTVRNANLQVTVHAGEAAGASSIWQAINKLGATRIGHGVKAIEDPTLLDYLVKHKI
GIESCLTSNSQTSTVSSFAKHPIKTFLAHGVLACLNSDDPAVEGIELAHEYQVAATKVGLNQDQIRQAQINGLEVAFLSD
AEKAALRNDALNR

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=336, Percent_Identity=30.952380952381, Blast_Score=140, Evalue=1e-33,
Organism=Escherichia coli, GI1787910, Length=328, Percent_Identity=64.3292682926829, Blast_Score=452, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI17538512, Length=337, Percent_Identity=32.6409495548961, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI32565969, Length=337, Percent_Identity=32.6409495548961, Blast_Score=125, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6324188, Length=331, Percent_Identity=25.3776435045317, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24645260, Length=327, Percent_Identity=23.2415902140673, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI45553183, Length=187, Percent_Identity=29.9465240641711, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17737615, Length=187, Percent_Identity=29.9465240641711, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 36434; Mature: 36434

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITNTLPLTDLHRHLDGNIRIETILELGQKFALPLPAYDIEGLRPYVQVVENEADLMAFL
CCCCCCCHHHHHHHCCCCEEHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCHHHHHHHH
SKLDWGVAVLGDLDACRRIAYENVQDVMHAKIDYAELRFSPYYMAMKHNLPLAGVVEAVV
HHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEEEECCCCHHHHHHHHH
DGVHAGCRDFSVKANLIGIMSRTFGKQRCQQELAALLTQKDKLVAIDLAGDELGHPGEHF
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHH
VEHFKTVRNANLQVTVHAGEAAGASSIWQAINKLGATRIGHGVKAIEDPTLLDYLVKHKI
HHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHCCHHHCCCCHHCCCHHHHHHHHHHHC
GIESCLTSNSQTSTVSSFAKHPIKTFLAHGVLACLNSDDPAVEGIELAHEYQVAATKVGL
CHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC
NQDQIRQAQINGLEVAFLSDAEKAALRNDALNR
CHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCC
>Mature Secondary Structure
MITNTLPLTDLHRHLDGNIRIETILELGQKFALPLPAYDIEGLRPYVQVVENEADLMAFL
CCCCCCCHHHHHHHCCCCEEHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCHHHHHHHH
SKLDWGVAVLGDLDACRRIAYENVQDVMHAKIDYAELRFSPYYMAMKHNLPLAGVVEAVV
HHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEEEECCCCHHHHHHHHH
DGVHAGCRDFSVKANLIGIMSRTFGKQRCQQELAALLTQKDKLVAIDLAGDELGHPGEHF
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHH
VEHFKTVRNANLQVTVHAGEAAGASSIWQAINKLGATRIGHGVKAIEDPTLLDYLVKHKI
HHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHCCHHHCCCCHHCCCHHHHHHHHHHHC
GIESCLTSNSQTSTVSSFAKHPIKTFLAHGVLACLNSDDPAVEGIELAHEYQVAATKVGL
CHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC
NQDQIRQAQINGLEVAFLSDAEKAALRNDALNR
CHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA