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The map label for this gene is ribE [H]

Identifier: 119945177

GI number: 119945177

Start: 1774814

End: 1775476

Strand: Direct

Name: ribE [H]

Synonym: Ping_1441

Alternate gene names: 119945177

Gene position: 1774814-1775476 (Clockwise)

Preceding gene: 119945176

Following gene: 119945178

Centisome position: 38.92

GC content: 39.06

Gene sequence:

>663_bases
ATGTTTACAGGAATTATAGCGGCAGTCGGTAAGGTGACTGCCATTAAAAAAAATGCCAAAGATATCACCATTAGCGTCGA
TGCAGGGAGCCTTGATTTAAGTGATGTAAAAGTGGGTGATAGCATTTCAAATAATGGTGTTTGCTTAACGGTGACCAAGT
TAAGTGATAAAAGTTTTAATGCCGATCTTTCTAACGAGACGTTAAAGCGCAGTGGTTTTTCTCAGATTAAAAATGGTTTT
GTGCTTAATTTAGAAAAAGCAATGCAAATGAATGACCGTTTTGGTGGACACATTGTTAGCGGGCATGTGGATGGTGTGGG
TGAAGTGATATCCGTTGACCCCCTTGGCAATGCCGTTGAATACTGGATTAAAGCGCCCGATGAATTGGCTAAATATATTG
CAGAAAAAGGATCTATTACCGTTGATGGTGTGAGTTTAACCACCAATGAAATTAACGGTGCTGCTTTCAAATTGACTATT
ATCCCGCACACAATTTCGCAAACGACTATGGTGAACTATAAAGTGGGCACCCAAGTCAATTTAGAAGTTGATGTTATTTC
ACGTTATTTAGAACGTTTAATGCTGGGTGATAAAGCCTCGACAAGTCAACATGATAATAAATCAACCATGGATCTGCTCG
CTAAAAGTGGTTTCTTAGGTTAA

Upstream 100 bases:

>100_bases
TCAAAAATGATTGAGGTTGTGCAATTATCACTGCAGAGTGTGGTTTTAATTGGCAATGATATTCGCATTATAAGTAACAT
TACAAGTGACAGGGGTTAAT

Downstream 100 bases:

>100_bases
GCCGACTATGAGATAGGTGAACTATACCCAGGTCAATTTAGAAGTTGACCTTATCGCTCGTTTTTAGAACGTTTAATGCT
GGGTGAACAAGCTTCGACAA

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MFTGIIAAVGKVTAIKKNAKDITISVDAGSLDLSDVKVGDSISNNGVCLTVTKLSDKSFNADLSNETLKRSGFSQIKNGF
VLNLEKAMQMNDRFGGHIVSGHVDGVGEVISVDPLGNAVEYWIKAPDELAKYIAEKGSITVDGVSLTTNEINGAAFKLTI
IPHTISQTTMVNYKVGTQVNLEVDVISRYLERLMLGDKASTSQHDNKSTMDLLAKSGFLG

Sequences:

>Translated_220_residues
MFTGIIAAVGKVTAIKKNAKDITISVDAGSLDLSDVKVGDSISNNGVCLTVTKLSDKSFNADLSNETLKRSGFSQIKNGF
VLNLEKAMQMNDRFGGHIVSGHVDGVGEVISVDPLGNAVEYWIKAPDELAKYIAEKGSITVDGVSLTTNEINGAAFKLTI
IPHTISQTTMVNYKVGTQVNLEVDVISRYLERLMLGDKASTSQHDNKSTMDLLAKSGFLG
>Mature_220_residues
MFTGIIAAVGKVTAIKKNAKDITISVDAGSLDLSDVKVGDSISNNGVCLTVTKLSDKSFNADLSNETLKRSGFSQIKNGF
VLNLEKAMQMNDRFGGHIVSGHVDGVGEVISVDPLGNAVEYWIKAPDELAKYIAEKGSITVDGVSLTTNEINGAAFKLTI
IPHTISQTTMVNYKVGTQVNLEVDVISRYLERLMLGDKASTSQHDNKSTMDLLAKSGFLG

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=185, Percent_Identity=36.2162162162162, Blast_Score=124, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6319733, Length=209, Percent_Identity=41.1483253588517, Blast_Score=145, Evalue=7e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 23513; Mature: 23513

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIIAAVGKVTAIKKNAKDITISVDAGSLDLSDVKVGDSISNNGVCLTVTKLSDKSFN
CCCHHHHHHHHHEEEECCCCEEEEEEECCCCCCCCEEECCCCCCCCEEEEEEEECCCCCC
ADLSNETLKRSGFSQIKNGFVLNLEKAMQMNDRFGGHIVSGHVDGVGEVISVDPLGNAVE
CCCCHHHHHHCCHHHHHCCEEEEHHHHHHHCCCCCCEEEECCCCCCCCEEEECCCCCHHH
YWIKAPDELAKYIAEKGSITVDGVSLTTNEINGAAFKLTIIPHTISQTTMVNYKVGTQVN
HEECCHHHHHHHHHHCCCEEEEEEEEEECCCCCEEEEEEEEECCCCCEEEEEEEECCEEE
LEVDVISRYLERLMLGDKASTSQHDNKSTMDLLAKSGFLG
EEHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MFTGIIAAVGKVTAIKKNAKDITISVDAGSLDLSDVKVGDSISNNGVCLTVTKLSDKSFN
CCCHHHHHHHHHEEEECCCCEEEEEEECCCCCCCCEEECCCCCCCCEEEEEEEECCCCCC
ADLSNETLKRSGFSQIKNGFVLNLEKAMQMNDRFGGHIVSGHVDGVGEVISVDPLGNAVE
CCCCHHHHHHCCHHHHHCCEEEEHHHHHHHCCCCCCEEEECCCCCCCCEEEECCCCCHHH
YWIKAPDELAKYIAEKGSITVDGVSLTTNEINGAAFKLTIIPHTISQTTMVNYKVGTQVN
HEECCHHHHHHHHHHCCCEEEEEEEEEECCCCCEEEEEEEEECCCCCEEEEEEEECCEEE
LEVDVISRYLERLMLGDKASTSQHDNKSTMDLLAKSGFLG
EEHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8144477 [H]