Click here to switch to the map view.

The map label for this gene is ltrA [H]

Identifier: 119945159

GI number: 119945159

Start: 1748361

End: 1749296

Strand: Direct

Name: ltrA [H]

Synonym: Ping_1423

Alternate gene names: 119945159

Gene position: 1748361-1749296 (Clockwise)

Preceding gene: 119945153

Following gene: 119945166

Centisome position: 38.34

GC content: 43.16

Gene sequence:

>936_bases
ATGAATAACATTATTTCCAAAAGTTGCATAATCATGGCAAAAACAGATGACCTTATCCTCTTTGCTCAGGTAGTAGAAGA
GGGCTCTTTTAGTAAAGTCGCAGAGCTAAATTCCCTTACAAATTCAGTAGTTAGCAAACGTATTAAACGATTGGAAGCGG
ATCTTGGGGTGCAGCTTTTGTATCGCACTACTCGAAAACTGACCGTCAGCGAAGCAGGAAAAGTACTTTATCAGGGTGCT
AAAAATGTGAAGCAGGCAGCATTAGAAGCGATTGACGCAGTGTATGGATACGGTGAAAGTGTTACGGGTCATCTTAAAAT
GTCAGTGCCGAGCATTTCTGGTGATTTAGTATTGGCCGGCGCAGTTGCTGAATTTTGCAGCATGCATCCCGGATTCAGCG
TTGATATGTCTCTGGAAAATTCCTTTATTGATATCGTTGGAGACGGTTATGACCTGGTGATACGCACTGGATATTTGGCA
GATTCGAGTTTAATCGCCCGGCATCTTATTGACTCTCAATGGGTTATCTGTGCAGCGCCTGCTTATATCAAGCGTTTTGG
CAAACCGATGACCCCGGAAGATCTGATTAATCACAATTGCCTGCAATATGCCTATCAAACAACGGGAGCATCTGAATGGG
AATTCAAAGGGATTAACGGTAACTATATTGTCAAAGTCGCGGGTAATTTTTCAACTGATAATGCGACTGCACTTAGAAAA
GCGGCGTTGGGCGGCTATGGCTTGGCTTATGTGCCGAAATGTTTGGTGTACCCGGATTTGTTGAAAGGTGATTTAGTGGA
TATATTCCCAGAACGGGTAGGTAAAAAGTTGGGTATTTACGCCGTTTATCCCTTTAGCCGTCAGCCCCCCTTAAAAATCC
GCATGCTGATCGAACACATCAGAGAACGCTATTTATCGATTGCAGAGTATTTTTAA

Upstream 100 bases:

>100_bases
AAATCTTTTTGGTTGTTGTTTGGCTATGTACGCAGTTTGTGAACCGTTTGTTAATTTGATGTTAAGATACGCCTATCTTT
TTTGTGGATATATGTAGATA

Downstream 100 bases:

>100_bases
CCCGTCATTAACCAAGAGGTTTCCCGATCAGTCAGCTTGTTGAGCAGGAAAAATGGGTTAAAGCATATCGATGCTGATCT
CATCAAAAGAATAAACCTTA

Product: transcriptional regulator, substrate-binding of LysR family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MNNIISKSCIIMAKTDDLILFAQVVEEGSFSKVAELNSLTNSVVSKRIKRLEADLGVQLLYRTTRKLTVSEAGKVLYQGA
KNVKQAALEAIDAVYGYGESVTGHLKMSVPSISGDLVLAGAVAEFCSMHPGFSVDMSLENSFIDIVGDGYDLVIRTGYLA
DSSLIARHLIDSQWVICAAPAYIKRFGKPMTPEDLINHNCLQYAYQTTGASEWEFKGINGNYIVKVAGNFSTDNATALRK
AALGGYGLAYVPKCLVYPDLLKGDLVDIFPERVGKKLGIYAVYPFSRQPPLKIRMLIEHIRERYLSIAEYF

Sequences:

>Translated_311_residues
MNNIISKSCIIMAKTDDLILFAQVVEEGSFSKVAELNSLTNSVVSKRIKRLEADLGVQLLYRTTRKLTVSEAGKVLYQGA
KNVKQAALEAIDAVYGYGESVTGHLKMSVPSISGDLVLAGAVAEFCSMHPGFSVDMSLENSFIDIVGDGYDLVIRTGYLA
DSSLIARHLIDSQWVICAAPAYIKRFGKPMTPEDLINHNCLQYAYQTTGASEWEFKGINGNYIVKVAGNFSTDNATALRK
AALGGYGLAYVPKCLVYPDLLKGDLVDIFPERVGKKLGIYAVYPFSRQPPLKIRMLIEHIRERYLSIAEYF
>Mature_311_residues
MNNIISKSCIIMAKTDDLILFAQVVEEGSFSKVAELNSLTNSVVSKRIKRLEADLGVQLLYRTTRKLTVSEAGKVLYQGA
KNVKQAALEAIDAVYGYGESVTGHLKMSVPSISGDLVLAGAVAEFCSMHPGFSVDMSLENSFIDIVGDGYDLVIRTGYLA
DSSLIARHLIDSQWVICAAPAYIKRFGKPMTPEDLINHNCLQYAYQTTGASEWEFKGINGNYIVKVAGNFSTDNATALRK
AALGGYGLAYVPKCLVYPDLLKGDLVDIFPERVGKKLGIYAVYPFSRQPPLKIRMLIEHIRERYLSIAEYF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=303, Percent_Identity=31.3531353135314, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI145693193, Length=289, Percent_Identity=32.1799307958478, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1786401, Length=291, Percent_Identity=30.2405498281787, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI87081978, Length=296, Percent_Identity=29.0540540540541, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1789440, Length=287, Percent_Identity=28.9198606271777, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1787128, Length=286, Percent_Identity=25.8741258741259, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787589, Length=274, Percent_Identity=25.9124087591241, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1788706, Length=288, Percent_Identity=27.0833333333333, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788481, Length=257, Percent_Identity=23.7354085603113, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789506, Length=260, Percent_Identity=23.8461538461538, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34258; Mature: 34258

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNIISKSCIIMAKTDDLILFAQVVEEGSFSKVAELNSLTNSVVSKRIKRLEADLGVQLL
CCCCCCCCEEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRTTRKLTVSEAGKVLYQGAKNVKQAALEAIDAVYGYGESVTGHLKMSVPSISGDLVLAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEEHH
AVAEFCSMHPGFSVDMSLENSFIDIVGDGYDLVIRTGYLADSSLIARHLIDSQWVICAAP
HHHHHHHCCCCCEEEEECCCCEEEEECCCEEEEEEECCCCCHHHHHHHHCCCCEEEEECH
AYIKRFGKPMTPEDLINHNCLQYAYQTTGASEWEFKGINGNYIVKVAGNFSTDNATALRK
HHHHHCCCCCCHHHHHCCHHHHHHHHCCCCCCCEEECCCCCEEEEEECCCCCCCHHHHHH
AALGGYGLAYVPKCLVYPDLLKGDLVDIFPERVGKKLGIYAVYPFSRQPPLKIRMLIEHI
HHCCCCCHHHHHHHHHCHHHHCCCHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHH
RERYLSIAEYF
HHHHHHHHHCC
>Mature Secondary Structure
MNNIISKSCIIMAKTDDLILFAQVVEEGSFSKVAELNSLTNSVVSKRIKRLEADLGVQLL
CCCCCCCCEEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRTTRKLTVSEAGKVLYQGAKNVKQAALEAIDAVYGYGESVTGHLKMSVPSISGDLVLAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEEHH
AVAEFCSMHPGFSVDMSLENSFIDIVGDGYDLVIRTGYLADSSLIARHLIDSQWVICAAP
HHHHHHHCCCCCEEEEECCCCEEEEECCCEEEEEEECCCCCHHHHHHHHCCCCEEEEECH
AYIKRFGKPMTPEDLINHNCLQYAYQTTGASEWEFKGINGNYIVKVAGNFSTDNATALRK
HHHHHCCCCCCHHHHHCCHHHHHHHHCCCCCCCEEECCCCCEEEEEECCCCCCCHHHHHH
AALGGYGLAYVPKCLVYPDLLKGDLVDIFPERVGKKLGIYAVYPFSRQPPLKIRMLIEHI
HHCCCCCHHHHHHHHHCHHHHCCCHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHH
RERYLSIAEYF
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]