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The map label for this gene is ompR [H]

Identifier: 119945114

GI number: 119945114

Start: 1693537

End: 1694247

Strand: Reverse

Name: ompR [H]

Synonym: Ping_1375

Alternate gene names: 119945114

Gene position: 1694247-1693537 (Counterclockwise)

Preceding gene: 119945125

Following gene: 119945113

Centisome position: 37.16

GC content: 39.94

Gene sequence:

>711_bases
ATGGAACAGCCTCATCTATTAATTGTCGATGACCACTATGAAATTCGTGAATTATTACAACGTTTTTTTATACAACATAA
CTATCGTGTCACTGTTGCCAAAGATGGCAAAGAGATGAAACGTTGTTTAAGCCTTTCAAAAATAGACTTGATAGTGTTGG
ATTTAATGCTGCCGGGTGAAGATGGTTTAAGTTTATGCCGCGGATTGCGTGTCTCATCTAATATCCCCATTGTGATGCTC
ACTGCAATGAGTGATGAAATGGATACAATTATAGGTCTTGAGATGGGCGCGGATGATTATCTGGCTAAACCTTTTAATCC
TCGCGAGTTATTAGCGCGTATTAAGGCCGTATTGCGCCGTGTAAATACTTTACATTCCCCCGTCTCTGACATTAAACGCT
ACCATTTTTCACACTGGTCTATTGATATTAATAAGCGTGAATTAACAGACAAAGAAGGTGTAATGGTGATATTAAGCAGT
GCTGAATTTGATCTGTTACGGGTGTTTATTGCCCATCCACAGAGAGTGTTAAATCGTGACCAATTGTTAGATTTAAGCAA
AGGACGTGAGGGAGGCGTCTATGATCGTTCAATAGACACGCTTATTAGTCGCTTGCGTAAAAAGCTGGAGCTAGATGCAA
AACACCCTGAAATAATTATCACCATTTGGGGCGGGGGATATCAATTTACCTGTGAGGTCACACATGATTAA

Upstream 100 bases:

>100_bases
TAATAGTTTGTGGCGAAAAGGCGTTTTGACATACTTTGATACAATTAAGATAAAAAAATAATATAATCTCTTATTTCATC
ATCAAGTTAAAGGAATCAGC

Downstream 100 bases:

>100_bases
GAAAATATCCCCTAAAAGCTTAGTCTCTCAAATCTGCCTGATTATGTTAATTGGGTTAAGTTTAGTGCTCTCGCTTTCTC
TGCAAATTTATTCCGATGAA

Product: two component transcriptional regulator, winged helix family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MEQPHLLIVDDHYEIRELLQRFFIQHNYRVTVAKDGKEMKRCLSLSKIDLIVLDLMLPGEDGLSLCRGLRVSSNIPIVML
TAMSDEMDTIIGLEMGADDYLAKPFNPRELLARIKAVLRRVNTLHSPVSDIKRYHFSHWSIDINKRELTDKEGVMVILSS
AEFDLLRVFIAHPQRVLNRDQLLDLSKGREGGVYDRSIDTLISRLRKKLELDAKHPEIIITIWGGGYQFTCEVTHD

Sequences:

>Translated_236_residues
MEQPHLLIVDDHYEIRELLQRFFIQHNYRVTVAKDGKEMKRCLSLSKIDLIVLDLMLPGEDGLSLCRGLRVSSNIPIVML
TAMSDEMDTIIGLEMGADDYLAKPFNPRELLARIKAVLRRVNTLHSPVSDIKRYHFSHWSIDINKRELTDKEGVMVILSS
AEFDLLRVFIAHPQRVLNRDQLLDLSKGREGGVYDRSIDTLISRLRKKLELDAKHPEIIITIWGGGYQFTCEVTHD
>Mature_236_residues
MEQPHLLIVDDHYEIRELLQRFFIQHNYRVTVAKDGKEMKRCLSLSKIDLIVLDLMLPGEDGLSLCRGLRVSSNIPIVML
TAMSDEMDTIIGLEMGADDYLAKPFNPRELLARIKAVLRRVNTLHSPVSDIKRYHFSHWSIDINKRELTDKEGVMVILSS
AEFDLLRVFIAHPQRVLNRDQLLDLSKGREGGVYDRSIDTLISRLRKKLELDAKHPEIIITIWGGGYQFTCEVTHD

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=46.551724137931, Blast_Score=211, Evalue=4e-56,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=42.0600858369099, Blast_Score=181, Evalue=3e-47,
Organism=Escherichia coli, GI1788394, Length=231, Percent_Identity=39.3939393939394, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=35.7758620689655, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=38.8646288209607, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=34.4827586206897, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1790860, Length=238, Percent_Identity=34.453781512605, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=36.4444444444444, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=37.7682403433476, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=34.3612334801762, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1787375, Length=230, Percent_Identity=34.3478260869565, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI87082012, Length=229, Percent_Identity=30.1310043668122, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=28.8888888888889, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1790552, Length=119, Percent_Identity=39.4957983193277, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790299, Length=140, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27178; Mature: 27178

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQPHLLIVDDHYEIRELLQRFFIQHNYRVTVAKDGKEMKRCLSLSKIDLIVLDLMLPGE
CCCCCEEEEECCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHEEEEEEECCCC
DGLSLCRGLRVSSNIPIVMLTAMSDEMDTIIGLEMGADDYLAKPFNPRELLARIKAVLRR
CHHHHHHCCCCCCCCCEEEEEECCCCCHHEEEEEECCCCHHCCCCCHHHHHHHHHHHHHH
VNTLHSPVSDIKRYHFSHWSIDINKRELTDKEGVMVILSSAEFDLLRVFIAHPQRVLNRD
HHHHCCCHHHHHHHCCCEEEEECCHHHCCCCCCEEEEEECCCHHHHHHHHHCCHHHHCHH
QLLDLSKGREGGVYDRSIDTLISRLRKKLELDAKHPEIIITIWGGGYQFTCEVTHD
HHEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEEEECCC
>Mature Secondary Structure
MEQPHLLIVDDHYEIRELLQRFFIQHNYRVTVAKDGKEMKRCLSLSKIDLIVLDLMLPGE
CCCCCEEEEECCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHEEEEEEECCCC
DGLSLCRGLRVSSNIPIVMLTAMSDEMDTIIGLEMGADDYLAKPFNPRELLARIKAVLRR
CHHHHHHCCCCCCCCCEEEEEECCCCCHHEEEEEECCCCHHCCCCCHHHHHHHHHHHHHH
VNTLHSPVSDIKRYHFSHWSIDINKRELTDKEGVMVILSSAEFDLLRVFIAHPQRVLNRD
HHHHCCCHHHHHHHCCCEEEEECCHHHCCCCCCEEEEEECCCHHHHHHHHHCCHHHHCHH
QLLDLSKGREGGVYDRSIDTLISRLRKKLELDAKHPEIIITIWGGGYQFTCEVTHD
HHEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]