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The map label for this gene is dinB [H]

Identifier: 119945086

GI number: 119945086

Start: 1663980

End: 1665059

Strand: Direct

Name: dinB [H]

Synonym: Ping_1342

Alternate gene names: 119945086

Gene position: 1663980-1665059 (Clockwise)

Preceding gene: 119945085

Following gene: 119945102

Centisome position: 36.49

GC content: 43.15

Gene sequence:

>1080_bases
TTGTCTGATCTTCCCCTCCCTCGGCAACGCAAAATTATCCATATTGACATGGATTCATTTTTTGCATCGGTGGAGATGCG
AGACGAACCAAGCTATAGAGGGATTCCTCTTGCAGTTGGAGGGAGTGAGCTTCAGCGCGGGGTGATTAGCACATCTAACT
ATGAGGCTCGTAAATATGGTGTGCGTTCTGCAATGGCAACTGCTCATGCCTTGAGATTGTGTCCACACTTAACCGTGGTT
CCTGGTCGAATACAGGTTTATAAAGAGATTTCAGCGCAAATTAGAGCTATTTTTGAGCGTTACACTCACTTAATCGAACC
TTTATCTTTAGATGAAGCTTTTCTTGATGTCACTGAATGCTGCCAATTACACGGCTCTGCAACACTTATTGCTGAAGCAA
TAAGAAATGATATCCGTAGGGAGTTGAATCTTACTGCTTCAGCTGGTGTTGCACCGATTAAGTTTTTAGCTAAAGTCGCT
TCTGATATGAATAAACCGGATGGTCAGTTTGTGATCCCTCCGGATAAGGTACAGAGCGTAATCGATACTCTACCACTGGA
GAAAATCCCTGGTGTTGGTAAGGTAAGCTTGCAAAAGCTTAATAATGCAGAGTTTTATGCCTGTGCGGATATTAAAAACA
GCAATTATTATGAATTACTTAGACGGTTCGGTCGTATGGGCGAGGCACTCTGGAATTTTAGCCATGGCATCGACAATCGC
GAAGTAGTTACTGAGCGAGAACGTAAGTCCGTCGGAGTAGAGCGTACATTTTCAATTAATATCACTACCTTTGAGGAATG
CTGGCTGTTCATCGAACGGAAGCTCTTTCCTGAGCTAGATAAACGACTTGGGCATGCTACTCCGGAGCGTTCGATCATCA
AACAGGGGATCAAGATGAAGTTTGCTGATTTTCAACTTACCACAATAGAGCATGGACATCACGAATTGGAGCTGGAATAT
TTCCGTGAACTATTGTGTGAAATTATCAAAAGACAGAATGGCAGAGAGATAAGGCTCCTCGGTCTAAGTGTGGTTTTAAA
ACCTGAAGGGCAAGTAAAACAGCTGAGCTTGGACTTATAA

Upstream 100 bases:

>100_bases
ACTCTTCGAACCCCTGTTGCTGCCAACCATTCCAATAAAAAGCAGTTGCATTTTAAGCAAAAAAGCCCAAAATAAATTGT
CTCTAAAACAGGTGGTTATT

Downstream 100 bases:

>100_bases
AACGTGCTAGTTCAGAGTTGATTTTATACTAAACTATCTATCCCTATAATCATTTAAAAACTTTAATTAACTTTTCTCGA
AATTCTCCAAAGGCTTCTAG

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MSDLPLPRQRKIIHIDMDSFFASVEMRDEPSYRGIPLAVGGSELQRGVISTSNYEARKYGVRSAMATAHALRLCPHLTVV
PGRIQVYKEISAQIRAIFERYTHLIEPLSLDEAFLDVTECCQLHGSATLIAEAIRNDIRRELNLTASAGVAPIKFLAKVA
SDMNKPDGQFVIPPDKVQSVIDTLPLEKIPGVGKVSLQKLNNAEFYACADIKNSNYYELLRRFGRMGEALWNFSHGIDNR
EVVTERERKSVGVERTFSINITTFEECWLFIERKLFPELDKRLGHATPERSIIKQGIKMKFADFQLTTIEHGHHELELEY
FRELLCEIIKRQNGREIRLLGLSVVLKPEGQVKQLSLDL

Sequences:

>Translated_359_residues
MSDLPLPRQRKIIHIDMDSFFASVEMRDEPSYRGIPLAVGGSELQRGVISTSNYEARKYGVRSAMATAHALRLCPHLTVV
PGRIQVYKEISAQIRAIFERYTHLIEPLSLDEAFLDVTECCQLHGSATLIAEAIRNDIRRELNLTASAGVAPIKFLAKVA
SDMNKPDGQFVIPPDKVQSVIDTLPLEKIPGVGKVSLQKLNNAEFYACADIKNSNYYELLRRFGRMGEALWNFSHGIDNR
EVVTERERKSVGVERTFSINITTFEECWLFIERKLFPELDKRLGHATPERSIIKQGIKMKFADFQLTTIEHGHHELELEY
FRELLCEIIKRQNGREIRLLGLSVVLKPEGQVKQLSLDL
>Mature_358_residues
SDLPLPRQRKIIHIDMDSFFASVEMRDEPSYRGIPLAVGGSELQRGVISTSNYEARKYGVRSAMATAHALRLCPHLTVVP
GRIQVYKEISAQIRAIFERYTHLIEPLSLDEAFLDVTECCQLHGSATLIAEAIRNDIRRELNLTASAGVAPIKFLAKVAS
DMNKPDGQFVIPPDKVQSVIDTLPLEKIPGVGKVSLQKLNNAEFYACADIKNSNYYELLRRFGRMGEALWNFSHGIDNRE
VVTERERKSVGVERTFSINITTFEECWLFIERKLFPELDKRLGHATPERSIIKQGIKMKFADFQLTTIEHGHHELELEYF
RELLCEIIKRQNGREIRLLGLSVVLKPEGQVKQLSLDL

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=337, Percent_Identity=31.4540059347181, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI7706681, Length=338, Percent_Identity=31.3609467455621, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI154350220, Length=293, Percent_Identity=29.6928327645051, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI7705344, Length=108, Percent_Identity=45.3703703703704, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI5729982, Length=360, Percent_Identity=26.1111111111111, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1786425, Length=354, Percent_Identity=57.0621468926554, Blast_Score=386, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI193205700, Length=407, Percent_Identity=28.009828009828, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17537959, Length=271, Percent_Identity=28.0442804428044, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI193205702, Length=222, Percent_Identity=29.7297297297297, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI115534089, Length=123, Percent_Identity=39.0243902439024, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324921, Length=289, Percent_Identity=25.2595155709343, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI19923006, Length=375, Percent_Identity=27.7333333333333, Blast_Score=148, Evalue=7e-36,
Organism=Drosophila melanogaster, GI21355641, Length=284, Percent_Identity=28.169014084507, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24644984, Length=284, Percent_Identity=28.169014084507, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24668444, Length=118, Percent_Identity=37.2881355932203, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 40834; Mature: 40703

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLPLPRQRKIIHIDMDSFFASVEMRDEPSYRGIPLAVGGSELQRGVISTSNYEARKYG
CCCCCCCCCCCEEEEEHHHHHEEEEECCCCCCCCCEEEECHHHHHHCCCCCCCCHHHHHH
VRSAMATAHALRLCPHLTVVPGRIQVYKEISAQIRAIFERYTHLIEPLSLDEAFLDVTEC
HHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
CQLHGSATLIAEAIRNDIRRELNLTASAGVAPIKFLAKVASDMNKPDGQFVIPPDKVQSV
HHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCEECCHHHHHHH
IDTLPLEKIPGVGKVSLQKLNNAEFYACADIKNSNYYELLRRFGRMGEALWNFSHGIDNR
HHHCCHHHCCCCCCHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCH
EVVTERERKSVGVERTFSINITTFEECWLFIERKLFPELDKRLGHATPERSIIKQGIKMK
HHHHHHHHHHCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEE
FADFQLTTIEHGHHELELEYFRELLCEIIKRQNGREIRLLGLSVVLKPEGQVKQLSLDL
EECEEEEEEECCCCEEEHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCEEEEECCC
>Mature Secondary Structure 
SDLPLPRQRKIIHIDMDSFFASVEMRDEPSYRGIPLAVGGSELQRGVISTSNYEARKYG
CCCCCCCCCCEEEEEHHHHHEEEEECCCCCCCCCEEEECHHHHHHCCCCCCCCHHHHHH
VRSAMATAHALRLCPHLTVVPGRIQVYKEISAQIRAIFERYTHLIEPLSLDEAFLDVTEC
HHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
CQLHGSATLIAEAIRNDIRRELNLTASAGVAPIKFLAKVASDMNKPDGQFVIPPDKVQSV
HHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCEECCHHHHHHH
IDTLPLEKIPGVGKVSLQKLNNAEFYACADIKNSNYYELLRRFGRMGEALWNFSHGIDNR
HHHCCHHHCCCCCCHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCH
EVVTERERKSVGVERTFSINITTFEECWLFIERKLFPELDKRLGHATPERSIIKQGIKMK
HHHHHHHHHHCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEE
FADFQLTTIEHGHHELELEYFRELLCEIIKRQNGREIRLLGLSVVLKPEGQVKQLSLDL
EECEEEEEEECCCCEEEHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA