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The map label for this gene is hmrR2 [H]

Identifier: 119945083

GI number: 119945083

Start: 1659881

End: 1660273

Strand: Reverse

Name: hmrR2 [H]

Synonym: Ping_1339

Alternate gene names: 119945083

Gene position: 1660273-1659881 (Counterclockwise)

Preceding gene: 119945084

Following gene: 119945077

Centisome position: 36.41

GC content: 37.4

Gene sequence:

>393_bases
ATGTTATCTATCGGTCAAGCAGCAAAAGCAACAGGATTATCGGTGAAATCAATCCGCCATTATGAACAGATAGGTTTGAT
CCCTCCCCCACCACGCAGTGAAAATGATTACCGCTGTTATCCCGCATCCTTAATTAAACGCTTACATTTTATTAAAAAAA
CCAAAGAAGCAGGTTTTAACTTAAAAGAGAGCAAAGCATTATTGTTATTATCTGAAAATAAAACCCGCAGCAGCGCAGAT
GTAAAAGCAATAACAATGCAAAAAATAGAAGAGTTACAGCACCGGATAGATCAACAGCAAATTTTATTAAATAGCCTGAA
AGAAATTTCCAAGCAGTGCCATAATGATGAAAACGCCCAGTGTGCGATCATTGATGCCTTTGTTAAGGGATAA

Upstream 100 bases:

>100_bases
AATCTATCGGGCAAGTCGATTTGGCATAATAAGCAAGTCGACAATCAGCTTATAGATTATTAAAATTTCACTTATATTTA
AGCAGTAACGGGCACTTTAT

Downstream 100 bases:

>100_bases
AAGTTAAGGGATAAAAGTTAAGGAATAAAGGTTAAAGAATCAAAGTTAAAAAAAAGCCCCTTTAGCTAAAAATAAAAATA
AAGGGGCTGTTATTTTCAAA

Product: transcriptional regulator of MerR family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 130; Mature: 130

Protein sequence:

>130_residues
MLSIGQAAKATGLSVKSIRHYEQIGLIPPPPRSENDYRCYPASLIKRLHFIKKTKEAGFNLKESKALLLLSENKTRSSAD
VKAITMQKIEELQHRIDQQQILLNSLKEISKQCHNDENAQCAIIDAFVKG

Sequences:

>Translated_130_residues
MLSIGQAAKATGLSVKSIRHYEQIGLIPPPPRSENDYRCYPASLIKRLHFIKKTKEAGFNLKESKALLLLSENKTRSSAD
VKAITMQKIEELQHRIDQQQILLNSLKEISKQCHNDENAQCAIIDAFVKG
>Mature_130_residues
MLSIGQAAKATGLSVKSIRHYEQIGLIPPPPRSENDYRCYPASLIKRLHFIKKTKEAGFNLKESKALLLLSENKTRSSAD
VKAITMQKIEELQHRIDQQQILLNSLKEISKQCHNDENAQCAIIDAFVKG

Specific function: Transcriptional regulator involved in acid tolerance. Binds copper [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786695, Length=124, Percent_Identity=39.5161290322581, Blast_Score=101, Evalue=2e-23,
Organism=Escherichia coli, GI1789687, Length=133, Percent_Identity=27.0676691729323, Blast_Score=64, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 14644; Mature: 14644

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSIGQAAKATGLSVKSIRHYEQIGLIPPPPRSENDYRCYPASLIKRLHFIKKTKEAGFN
CCCCCCCCHHCCCHHHHHHHHHHCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHCCC
LKESKALLLLSENKTRSSADVKAITMQKIEELQHRIDQQQILLNSLKEISKQCHNDENAQ
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
CAIIDAFVKG
EEEEEEECCC
>Mature Secondary Structure
MLSIGQAAKATGLSVKSIRHYEQIGLIPPPPRSENDYRCYPASLIKRLHFIKKTKEAGFN
CCCCCCCCHHCCCHHHHHHHHHHCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHCCC
LKESKALLLLSENKTRSSADVKAITMQKIEELQHRIDQQQILLNSLKEISKQCHNDENAQ
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
CAIIDAFVKG
EEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]