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The map label for this gene is yrhP [H]

Identifier: 119945077

GI number: 119945077

Start: 1651402

End: 1652040

Strand: Reverse

Name: yrhP [H]

Synonym: Ping_1333

Alternate gene names: 119945077

Gene position: 1652040-1651402 (Counterclockwise)

Preceding gene: 119945083

Following gene: 119945065

Centisome position: 36.23

GC content: 43.19

Gene sequence:

>639_bases
ATGCACATATTAAATTTTGAAGCCTTTTTAATCGCGATAACGATTCTCACTTTAACACCGGGTTTAGATACTGCGCTGGT
TATTCGCAATGCTAGCCGTTCGGGGGGAATCGACGGTTGTGTGACCAGTTTGGGGATCTGCCTGGGGCTGTTTGTCCACG
CGACATTATCAGCTGTGGGTATTTCAGCTATTTTGCTGCAATCAGCACAACTGTTTCAGGTTATGAAGTGGTGTGGAGCA
GCGTATTTAATTTGGCTGGGCTTAAGTAGCCTTAGGGCCACCTTTAAAGGTGCAAGCCATCTCAATATAAGCACCTGCAC
TGGGGTTACATTTGATCCCAAACGCTCCCTTCGTGAAGGTTTTTTATCTAATGTACTTAACCCCAAAACAGCTATTTTCT
ACCTTGCTTTTTTACCGCAATTTATTAATCCCGATTACTCCCCCTTTGTACAGTCACTTACCTTGGCGGGTATTCATTTT
TTAATTGCGATGGTCTGGCAATGCAGCTTGTCCGGCGCAATTAATTCTGCTAAAAACTGGTTAAAAAACACTTCTATTAT
GACTTGGATGGAGGGTGTGACCGGCACTGTATTGATTCTCCTGGGCATAAAATTATTAATGGATGACTCAGTCGTTTAG

Upstream 100 bases:

>100_bases
TTTATGTCCTAAAATTAACCGCCTGTAATAGTTGTACGACTTTACATACTCACCTAATTCTTGGTATAACAGATAAATTA
AAAATTGAAGAGCAAAGCCG

Downstream 100 bases:

>100_bases
CTTAAAAAACACATTAATGATGACCAGAATGGAGGTGTAACCGGCACTGTGCTGATTCTATTGGGCGTGGAATTATTGAT
GGATGACTCAGTGGTTTAGC

Product: lysine exporter protein LysE/YggA

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MHILNFEAFLIAITILTLTPGLDTALVIRNASRSGGIDGCVTSLGICLGLFVHATLSAVGISAILLQSAQLFQVMKWCGA
AYLIWLGLSSLRATFKGASHLNISTCTGVTFDPKRSLREGFLSNVLNPKTAIFYLAFLPQFINPDYSPFVQSLTLAGIHF
LIAMVWQCSLSGAINSAKNWLKNTSIMTWMEGVTGTVLILLGIKLLMDDSVV

Sequences:

>Translated_212_residues
MHILNFEAFLIAITILTLTPGLDTALVIRNASRSGGIDGCVTSLGICLGLFVHATLSAVGISAILLQSAQLFQVMKWCGA
AYLIWLGLSSLRATFKGASHLNISTCTGVTFDPKRSLREGFLSNVLNPKTAIFYLAFLPQFINPDYSPFVQSLTLAGIHF
LIAMVWQCSLSGAINSAKNWLKNTSIMTWMEGVTGTVLILLGIKLLMDDSVV
>Mature_212_residues
MHILNFEAFLIAITILTLTPGLDTALVIRNASRSGGIDGCVTSLGICLGLFVHATLSAVGISAILLQSAQLFQVMKWCGA
AYLIWLGLSSLRATFKGASHLNISTCTGVTFDPKRSLREGFLSNVLNPKTAIFYLAFLPQFINPDYSPFVQSLTLAGIHF
LIAMVWQCSLSGAINSAKNWLKNTSIMTWMEGVTGTVLILLGIKLLMDDSVV

Specific function: Conducts The Efflux Of Homoserine And Homoserine Lactone. [C]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=197, Percent_Identity=30.9644670050761, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788099, Length=145, Percent_Identity=28.2758620689655, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786522, Length=176, Percent_Identity=25.5681818181818, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22885; Mature: 22885

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHILNFEAFLIAITILTLTPGLDTALVIRNASRSGGIDGCVTSLGICLGLFVHATLSAVG
CCEECHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ISAILLQSAQLFQVMKWCGAAYLIWLGLSSLRATFKGASHLNISTCTGVTFDPKRSLREG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHH
FLSNVLNPKTAIFYLAFLPQFINPDYSPFVQSLTLAGIHFLIAMVWQCSLSGAINSAKNW
HHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKNTSIMTWMEGVTGTVLILLGIKLLMDDSVV
HHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MHILNFEAFLIAITILTLTPGLDTALVIRNASRSGGIDGCVTSLGICLGLFVHATLSAVG
CCEECHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ISAILLQSAQLFQVMKWCGAAYLIWLGLSSLRATFKGASHLNISTCTGVTFDPKRSLREG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHH
FLSNVLNPKTAIFYLAFLPQFINPDYSPFVQSLTLAGIHFLIAMVWQCSLSGAINSAKNW
HHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKNTSIMTWMEGVTGTVLILLGIKLLMDDSVV
HHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 9308178 [H]