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The map label for this gene is hscB

Identifier: 119945071

GI number: 119945071

Start: 1645308

End: 1645817

Strand: Direct

Name: hscB

Synonym: Ping_1327

Alternate gene names: 119945071

Gene position: 1645308-1645817 (Clockwise)

Preceding gene: 119945070

Following gene: 119945072

Centisome position: 36.08

GC content: 36.47

Gene sequence:

>510_bases
GTGAATTACTTCGATCTATTTTCTCTTCCGGTTATATTTCCAATTGATCAAACTCGATTATCCGAAACTTACCGCGAACT
GCAAAAGCAATACCATCCGGATAAATTTGTGATGCAAAACGACAGTGAACGTTTGCGCGCAATGCAGAAAAGCACCGAAA
TAAATGATGCTTATCAGACATTAAAAAACAGTTGTTTACGTGCACAATATTTGCTTTTATTGGCCGGCCTGGATATCGCT
TTAGAACATAAAACATTACAAGATACTGCTTTCTTGGTGCAGCAGATGGAATGGCGTGAAACTATCGCAGCATTTACAGA
AGATGATCAAGATAAAATGGATGAATTTGCACTGCAATTACAGCAGCAGGTCGCAGGTTTAGAGTCAAAGATAGAAGTGC
AACTTCAAAATGATGAATTGGAAGCAACTGCGGACAGCATCAGACAATTAAAATTTATGCTCAAACTTCAAATTGAATTA
GTATTAATCGAAGAAAAATTATTTGATTAA

Upstream 100 bases:

>100_bases
TTAACACTTAAATTTAATCCTTTAACCCGTTATACTGATAAATCGTATTTTTACTGAGGAATTATGTTTACATTTTTCCT
CTTTTTTTTAGGGAACTGTT

Downstream 100 bases:

>100_bases
TACTAATACCAAAAGAATTAAAAAGGTGATCAGCTTTGCTGGTTAAAATTATCCCTAACTGTGTGATGAGTTTTATTTAG
ACGATCTTGTTCTTTACCAC

Product: co-chaperone Hsc20

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MNYFDLFSLPVIFPIDQTRLSETYRELQKQYHPDKFVMQNDSERLRAMQKSTEINDAYQTLKNSCLRAQYLLLLAGLDIA
LEHKTLQDTAFLVQQMEWRETIAAFTEDDQDKMDEFALQLQQQVAGLESKIEVQLQNDELEATADSIRQLKFMLKLQIEL
VLIEEKLFD

Sequences:

>Translated_169_residues
MNYFDLFSLPVIFPIDQTRLSETYRELQKQYHPDKFVMQNDSERLRAMQKSTEINDAYQTLKNSCLRAQYLLLLAGLDIA
LEHKTLQDTAFLVQQMEWRETIAAFTEDDQDKMDEFALQLQQQVAGLESKIEVQLQNDELEATADSIRQLKFMLKLQIEL
VLIEEKLFD
>Mature_169_residues
MNYFDLFSLPVIFPIDQTRLSETYRELQKQYHPDKFVMQNDSERLRAMQKSTEINDAYQTLKNSCLRAQYLLLLAGLDIA
LEHKTLQDTAFLVQQMEWRETIAAFTEDDQDKMDEFALQLQQQVAGLESKIEVQLQNDELEATADSIRQLKFMLKLQIEL
VLIEEKLFD

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain

Homologues:

Organism=Escherichia coli, GI1788876, Length=170, Percent_Identity=40, Blast_Score=126, Evalue=6e-31,
Organism=Drosophila melanogaster, GI161084223, Length=159, Percent_Identity=28.9308176100629, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSCB_PSYIN (A1SUI7)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_942751.1
- ProteinModelPortal:   A1SUI7
- SMR:   A1SUI7
- STRING:   A1SUI7
- GeneID:   4626440
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_1327
- eggNOG:   COG1076
- HOGENOM:   HBG751004
- OMA:   INDSESK
- PhylomeDB:   A1SUI7
- BioCyc:   PING357804:PING_1327-MONOMER
- HAMAP:   MF_00682
- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640
- InterPro:   IPR015609
- Gene3D:   G3DSA:1.10.287.110
- Gene3D:   G3DSA:1.20.1280.20
- PANTHER:   PTHR11821
- SMART:   SM00271
- TIGRFAMs:   TIGR00714

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C; SSF46565 DnaJ_N; SSF47144 HSC20_C

EC number: NA

Molecular weight: Translated: 19900; Mature: 19900

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: PS00636 DNAJ_1; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYFDLFSLPVIFPIDQTRLSETYRELQKQYHPDKFVMQNDSERLRAMQKSTEINDAYQT
CCCHHHHCCCEEECCCHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHCCHHHHHHH
LKNSCLRAQYLLLLAGLDIALEHKTLQDTAFLVQQMEWRETIAAFTEDDQDKMDEFALQL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QQQVAGLESKIEVQLQNDELEATADSIRQLKFMLKLQIELVLIEEKLFD
HHHHHCCCHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEEECHHHCC
>Mature Secondary Structure
MNYFDLFSLPVIFPIDQTRLSETYRELQKQYHPDKFVMQNDSERLRAMQKSTEINDAYQT
CCCHHHHCCCEEECCCHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHCCHHHHHHH
LKNSCLRAQYLLLLAGLDIALEHKTLQDTAFLVQQMEWRETIAAFTEDDQDKMDEFALQL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QQQVAGLESKIEVQLQNDELEATADSIRQLKFMLKLQIELVLIEEKLFD
HHHHHCCCHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEEECHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA