| Definition | Psychromonas ingrahamii 37, complete genome. |
|---|---|
| Accession | NC_008709 |
| Length | 4,559,598 |
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The map label for this gene is thrA [H]
Identifier: 119945021
GI number: 119945021
Start: 1580888
End: 1583350
Strand: Direct
Name: thrA [H]
Synonym: Ping_1275
Alternate gene names: 119945021
Gene position: 1580888-1583350 (Clockwise)
Preceding gene: 119945020
Following gene: 119945022
Centisome position: 34.67
GC content: 41.49
Gene sequence:
>2463_bases ATGCGCGTACTTAAATTTGGCGGGTCATCATTAGCAAATGCCGAACGTTTTAATCAGGTTGCTGATATTGTTATTAATAA TCAGCAGCAATCTCAAATTGCTTTAGTTTTATCTGCACCGGCGGGTGTCACCAACAATCTAGTCGCTGTTGTTGAAAAAA CCAGTATGGGTATATCTTCAGAAAGCCACTTAATTGATATTCAAAATATTTTTGCTGATCTCATCAAAACACTGAAGGGG ACTTATGCAGAGTTTGCAGATGAATTACTGGAAACTATTTTTGAGCGTGAATTGTCACATTTAAGTGATTTGCTTGAAGG TGTGCGTTTGCTAGCACAATGCCCTGCCAGTATCGAAGCTCAAATATTAAGCAAGGGTGAATTGCTTAGTGTCGCCTGTA TGAAGCAATTGTTAATCGCTAAGGGTCATCAGGTAGAAATCATTAAACCACAAGAAAAGCTTATTTCTTACAAAGGTGGT TATCTTGAAGCGCAAATCGATATTGACGTTTCCCGTGCATTGTTTGAAAAAGAAACCATTGTCAAAGATGCTATCTACTT GATGCCTGGTTTTACAGCAGGTAATGAGCAGGGTGAAACACTTGTATTAGGTCGTAACGGCTCGGATTACTCGGCTGCTG TGTTAGCGGCTTGTTTAAAAGCTGAATGTTGTGAAATCTGGACCGATGTTGATGGTGTATACAGTTGTGATCCGCGTTTG GTAAAAGATGCAAAATTATTAAGTTCGTTAAGTTATGCTGAAGCCATGGAGCTTTCATATTTTGGTGCTAAAGTATTACA CCCTAAAACGATTACCCCGATAGCGCAGCACCATATACCCTGTTTAATAAAAAACACCTATAACCCGCAAGCAAATGGTA CTTTAATTGGAGTAGAACATGGCGATGAGGCATTGCAAGTGAAAGGTATCTCTGATCTTAAGGGGCTCTCCATGCTGAGT ATCTCAGGACCCGGGATGAAAGGCATCGTTGGCATGGCGGGGCGTATATTCACGACCGTCTCACGTTCAGGTGTGTCGAT TATTTTGATTACGCAATCATCGTCTGAATACAGTTTAAGCTTTTGTATTCACTCTAGTGAGACACAAAAAGCCTTGTATG CATTAAATGAGGAGTTCTCTTTAGAATTTAAAAATCATTTATTAGAGCCTATTGATGTGGTTGAAAAGCAGGCTATCATA TCACTGGTTGGTGATGGCATGAAAAAAGCACGCGGGGTGGCCGCGCGTTTTCTAACCGCCTTAACGGAAGCTTCTATTAA CATTACTGCGATTGCGCAGGGTTCATCTGAGCGTTCTATTTCAGCGGTTGTATCAGAGGAAAAAGCAAAAGAAGCGGTCA TCGCTTGTCATCAAAACTTTTTTGGTAGTGTGCAATATATAGATATGTTCCTTATCGGCTGTGGTGGGGTAGGATCAGCA CTGGTTGATCAAATACATCGTCAACAGGCTTACTTATCAGAACGAAATATTGAAATTCGCGTCTGCGGCATTGCCGACAG TCGTAAGATGTTAATGGACGATCAAGGCATTCAATTAAGCAACTGGCGTGAGTTATTAGCCACTGCAACAGAAGAGTTAT CCTTGTCCAGTATGCAATCTATGGTCGATGACTCACATATTATTAACCCTGTCATTGTTGACTGTACCAGCAATGATGCG ATTGCCGCGCGTTATGTTGACTTTTTGGGCGCGGGTTTCCACGTTGTTGCTGCCAACAAAAAAGCCAATACTTTCAGTAT GGATTATTACCACCAACTGCGTTTAACCGCGTTAATGAAACGTCGTAAATTCTTGTATGATACCAATGTTGGCGCAGGTT TGCCGGTCATAGAAAATATGCAAAACCTGTTTAATGCGGGCGATCAGTTAGTCAAGTTTAACGGTATATTATCGGGTTCA TTGTCATTTATTTTTGGTAAACTGGACGATGGTAAGAAATTTTCCGAGGTAACCGCAGAAGCGCGTAAGCTTGGTTTTAC TGAGCCCGATCCTCGTGAAGACTTAAGCGGCACGGATGTCGCGCGCAAACTGCTTATTTTAGCACGTGAGGCAGGGATGG AATTATCGCTTGATGATGTTGAAATTGAACCTGCATTACCACCTGGTTTTGACGAAACAGGGAGTGTTGATGAATTTATG ACTCGCTTGCCGGAGGCTGATGCTTATTTTGCTGAATTGCAGGCTAAAGCTGACGAAAATGGTCAAGTGCTACGCTATAT TGGCGGCATTGAAAACGGTAAATGTAAATGCAGTATTAAAGCGGTCAATGAAGATGACCCGCTTAACAAAGTAAAAGACG GTGAAAATGCATTGGCATTTTATAGTCAGTATTATCAACCTATTCCATTAGTTTTACGTGGTTACGGTGCTGGATCAGAA GTGACTGCTGCGGGTGTTTTTGCCGATGTATTACGTACTTTAAATTGGAAACAGGAGTTTTAA
Upstream 100 bases:
>100_bases TTAAATAACGCCTCTGTTTTTGTTCTATTTATTAAATAAATCATCGTCTTTACAAAACCCGCATTTCTGCGGGTTTTGCG TATCATAACAGGGAGTATCA
Downstream 100 bases:
>100_bases GATGAGTGTTGTGGCATATGCTCCAGCGTCGACTGCAAATGTTAGTGTAGGTTTTGATGTATTGGGAGGGGCACTTACCC CTATTAATGGCGATTTATTT
Product: bifunctional aspartokinase I/homeserine dehydrogenase I
Products: NA
Alternate protein names: Aspartokinase I/homoserine dehydrogenase I; AKI-HDI; Aspartokinase; Homoserine dehydrogenase [H]
Number of amino acids: Translated: 820; Mature: 820
Protein sequence:
>820_residues MRVLKFGGSSLANAERFNQVADIVINNQQQSQIALVLSAPAGVTNNLVAVVEKTSMGISSESHLIDIQNIFADLIKTLKG TYAEFADELLETIFERELSHLSDLLEGVRLLAQCPASIEAQILSKGELLSVACMKQLLIAKGHQVEIIKPQEKLISYKGG YLEAQIDIDVSRALFEKETIVKDAIYLMPGFTAGNEQGETLVLGRNGSDYSAAVLAACLKAECCEIWTDVDGVYSCDPRL VKDAKLLSSLSYAEAMELSYFGAKVLHPKTITPIAQHHIPCLIKNTYNPQANGTLIGVEHGDEALQVKGISDLKGLSMLS ISGPGMKGIVGMAGRIFTTVSRSGVSIILITQSSSEYSLSFCIHSSETQKALYALNEEFSLEFKNHLLEPIDVVEKQAII SLVGDGMKKARGVAARFLTALTEASINITAIAQGSSERSISAVVSEEKAKEAVIACHQNFFGSVQYIDMFLIGCGGVGSA LVDQIHRQQAYLSERNIEIRVCGIADSRKMLMDDQGIQLSNWRELLATATEELSLSSMQSMVDDSHIINPVIVDCTSNDA IAARYVDFLGAGFHVVAANKKANTFSMDYYHQLRLTALMKRRKFLYDTNVGAGLPVIENMQNLFNAGDQLVKFNGILSGS LSFIFGKLDDGKKFSEVTAEARKLGFTEPDPREDLSGTDVARKLLILAREAGMELSLDDVEIEPALPPGFDETGSVDEFM TRLPEADAYFAELQAKADENGQVLRYIGGIENGKCKCSIKAVNEDDPLNKVKDGENALAFYSQYYQPIPLVLRGYGAGSE VTAAGVFADVLRTLNWKQEF
Sequences:
>Translated_820_residues MRVLKFGGSSLANAERFNQVADIVINNQQQSQIALVLSAPAGVTNNLVAVVEKTSMGISSESHLIDIQNIFADLIKTLKG TYAEFADELLETIFERELSHLSDLLEGVRLLAQCPASIEAQILSKGELLSVACMKQLLIAKGHQVEIIKPQEKLISYKGG YLEAQIDIDVSRALFEKETIVKDAIYLMPGFTAGNEQGETLVLGRNGSDYSAAVLAACLKAECCEIWTDVDGVYSCDPRL VKDAKLLSSLSYAEAMELSYFGAKVLHPKTITPIAQHHIPCLIKNTYNPQANGTLIGVEHGDEALQVKGISDLKGLSMLS ISGPGMKGIVGMAGRIFTTVSRSGVSIILITQSSSEYSLSFCIHSSETQKALYALNEEFSLEFKNHLLEPIDVVEKQAII SLVGDGMKKARGVAARFLTALTEASINITAIAQGSSERSISAVVSEEKAKEAVIACHQNFFGSVQYIDMFLIGCGGVGSA LVDQIHRQQAYLSERNIEIRVCGIADSRKMLMDDQGIQLSNWRELLATATEELSLSSMQSMVDDSHIINPVIVDCTSNDA IAARYVDFLGAGFHVVAANKKANTFSMDYYHQLRLTALMKRRKFLYDTNVGAGLPVIENMQNLFNAGDQLVKFNGILSGS LSFIFGKLDDGKKFSEVTAEARKLGFTEPDPREDLSGTDVARKLLILAREAGMELSLDDVEIEPALPPGFDETGSVDEFM TRLPEADAYFAELQAKADENGQVLRYIGGIENGKCKCSIKAVNEDDPLNKVKDGENALAFYSQYYQPIPLVLRGYGAGSE VTAAGVFADVLRTLNWKQEF >Mature_820_residues MRVLKFGGSSLANAERFNQVADIVINNQQQSQIALVLSAPAGVTNNLVAVVEKTSMGISSESHLIDIQNIFADLIKTLKG TYAEFADELLETIFERELSHLSDLLEGVRLLAQCPASIEAQILSKGELLSVACMKQLLIAKGHQVEIIKPQEKLISYKGG YLEAQIDIDVSRALFEKETIVKDAIYLMPGFTAGNEQGETLVLGRNGSDYSAAVLAACLKAECCEIWTDVDGVYSCDPRL VKDAKLLSSLSYAEAMELSYFGAKVLHPKTITPIAQHHIPCLIKNTYNPQANGTLIGVEHGDEALQVKGISDLKGLSMLS ISGPGMKGIVGMAGRIFTTVSRSGVSIILITQSSSEYSLSFCIHSSETQKALYALNEEFSLEFKNHLLEPIDVVEKQAII SLVGDGMKKARGVAARFLTALTEASINITAIAQGSSERSISAVVSEEKAKEAVIACHQNFFGSVQYIDMFLIGCGGVGSA LVDQIHRQQAYLSERNIEIRVCGIADSRKMLMDDQGIQLSNWRELLATATEELSLSSMQSMVDDSHIINPVIVDCTSNDA IAARYVDFLGAGFHVVAANKKANTFSMDYYHQLRLTALMKRRKFLYDTNVGAGLPVIENMQNLFNAGDQLVKFNGILSGS LSFIFGKLDDGKKFSEVTAEARKLGFTEPDPREDLSGTDVARKLLILAREAGMELSLDDVEIEPALPPGFDETGSVDEFM TRLPEADAYFAELQAKADENGQVLRYIGGIENGKCKCSIKAVNEDDPLNKVKDGENALAFYSQYYQPIPLVLRGYGAGSE VTAAGVFADVLRTLNWKQEF
Specific function: Catalyzes 2 nonconsecutive reactions in the common biosynthetic pathway leading from Asp to diaminopimelate and Lys, to Met, and to Thr and Ile. [C]
COG id: COG0527
COG function: function code E; Aspartokinases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 ACT domains [H]
Homologues:
Organism=Escherichia coli, GI1786183, Length=818, Percent_Identity=59.9022004889976, Blast_Score=986, Evalue=0.0, Organism=Escherichia coli, GI1790376, Length=815, Percent_Identity=31.7791411042945, Blast_Score=353, Evalue=2e-98, Organism=Escherichia coli, GI1790455, Length=460, Percent_Identity=31.0869565217391, Blast_Score=176, Evalue=8e-45, Organism=Saccharomyces cerevisiae, GI6322599, Length=363, Percent_Identity=33.8842975206612, Blast_Score=162, Evalue=2e-40, Organism=Saccharomyces cerevisiae, GI6320893, Length=500, Percent_Identity=26.8, Blast_Score=148, Evalue=4e-36,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002912 - InterPro: IPR001048 - InterPro: IPR005106 - InterPro: IPR001341 - InterPro: IPR018042 - InterPro: IPR011147 - InterPro: IPR001342 - InterPro: IPR019811 - InterPro: IPR016040 [H]
Pfam domain/function: PF00696 AA_kinase; PF01842 ACT; PF00742 Homoserine_dh; PF03447 NAD_binding_3 [H]
EC number: =2.7.2.4; =1.1.1.3 [H]
Molecular weight: Translated: 89312; Mature: 89312
Theoretical pI: Translated: 4.76; Mature: 4.76
Prosite motif: PS01042 HOMOSER_DHGENASE ; PS00324 ASPARTOKINASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.7 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 4.0 %Cys+Met (Translated Protein) 1.7 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 4.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRVLKFGGSSLANAERFNQVADIVINNQQQSQIALVLSAPAGVTNNLVAVVEKTSMGISS CEEEEECCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEEEEHHHCCCCC ESHLIDIQNIFADLIKTLKGTYAEFADELLETIFERELSHLSDLLEGVRLLAQCPASIEA CCCEEEHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH QILSKGELLSVACMKQLLIAKGHQVEIIKPQEKLISYKGGYLEAQIDIDVSRALFEKETI HHHCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHCCCCEEEEEEECHHHHHHHHHHHH VKDAIYLMPGFTAGNEQGETLVLGRNGSDYSAAVLAACLKAECCEIWTDVDGVYSCDPRL HHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH VKDAKLLSSLSYAEAMELSYFGAKVLHPKTITPIAQHHIPCLIKNTYNPQANGTLIGVEH HHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHCCCEEEECCCCCCCCCEEEEEEC GDEALQVKGISDLKGLSMLSISGPGMKGIVGMAGRIFTTVSRSGVSIILITQSSSEYSLS CCCEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEE FCIHSSETQKALYALNEEFSLEFKNHLLEPIDVVEKQAIISLVGDGMKKARGVAARFLTA EEEECCCHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH LTEASINITAIAQGSSERSISAVVSEEKAKEAVIACHQNFFGSVQYIDMFLIGCGGVGSA HHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEHEEECCCCHHH LVDQIHRQQAYLSERNIEIRVCGIADSRKMLMDDQGIQLSNWRELLATATEELSLSSMQS HHHHHHHHHHHHHHCCEEEEEEECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH MVDDSHIINPVIVDCTSNDAIAARYVDFLGAGFHVVAANKKANTFSMDYYHQLRLTALMK HHCCCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCEEEHHHHHHHHHHHHHH RRKFLYDTNVGAGLPVIENMQNLFNAGDQLVKFNGILSGSLSFIFGKLDDGKKFSEVTAE HHHHHEECCCCCCCHHHHHHHHHHCCCCCEEEECCEEECCCEEEEEECCCCCHHHHHHHH ARKLGFTEPDPREDLSGTDVARKLLILAREAGMELSLDDVEIEPALPPGFDETGSVDEFM HHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCEEECCCCCCCCCCCCCHHHHH TRLPEADAYFAELQAKADENGQVLRYIGGIENGKCKCSIKAVNEDDPLNKVKDGENALAF HHCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEEECCCCCCCHHHCCCCHHHHH YSQYYQPIPLVLRGYGAGSEVTAAGVFADVLRTLNWKQEF HHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCC >Mature Secondary Structure MRVLKFGGSSLANAERFNQVADIVINNQQQSQIALVLSAPAGVTNNLVAVVEKTSMGISS CEEEEECCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEEEEHHHCCCCC ESHLIDIQNIFADLIKTLKGTYAEFADELLETIFERELSHLSDLLEGVRLLAQCPASIEA CCCEEEHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH QILSKGELLSVACMKQLLIAKGHQVEIIKPQEKLISYKGGYLEAQIDIDVSRALFEKETI HHHCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHCCCCEEEEEEECHHHHHHHHHHHH VKDAIYLMPGFTAGNEQGETLVLGRNGSDYSAAVLAACLKAECCEIWTDVDGVYSCDPRL HHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH VKDAKLLSSLSYAEAMELSYFGAKVLHPKTITPIAQHHIPCLIKNTYNPQANGTLIGVEH HHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHCCCEEEECCCCCCCCCEEEEEEC GDEALQVKGISDLKGLSMLSISGPGMKGIVGMAGRIFTTVSRSGVSIILITQSSSEYSLS CCCEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEE FCIHSSETQKALYALNEEFSLEFKNHLLEPIDVVEKQAIISLVGDGMKKARGVAARFLTA EEEECCCHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH LTEASINITAIAQGSSERSISAVVSEEKAKEAVIACHQNFFGSVQYIDMFLIGCGGVGSA HHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEHEEECCCCHHH LVDQIHRQQAYLSERNIEIRVCGIADSRKMLMDDQGIQLSNWRELLATATEELSLSSMQS HHHHHHHHHHHHHHCCEEEEEEECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH MVDDSHIINPVIVDCTSNDAIAARYVDFLGAGFHVVAANKKANTFSMDYYHQLRLTALMK HHCCCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCEEEHHHHHHHHHHHHHH RRKFLYDTNVGAGLPVIENMQNLFNAGDQLVKFNGILSGSLSFIFGKLDDGKKFSEVTAE HHHHHEECCCCCCCHHHHHHHHHHCCCCCEEEECCEEECCCEEEEEECCCCCHHHHHHHH ARKLGFTEPDPREDLSGTDVARKLLILAREAGMELSLDDVEIEPALPPGFDETGSVDEFM HHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCEEECCCCCCCCCCCCCHHHHH TRLPEADAYFAELQAKADENGQVLRYIGGIENGKCKCSIKAVNEDDPLNKVKDGENALAF HHCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEEECCCCCCCHHHCCCCHHHHH YSQYYQPIPLVLRGYGAGSEVTAAGVFADVLRTLNWKQEF HHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8423151 [H]