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The map label for this gene is trpB

Identifier: 119944814

GI number: 119944814

Start: 1329738

End: 1330925

Strand: Reverse

Name: trpB

Synonym: Ping_1056

Alternate gene names: 119944814

Gene position: 1330925-1329738 (Counterclockwise)

Preceding gene: 119944815

Following gene: 119944813

Centisome position: 29.19

GC content: 43.27

Gene sequence:

>1188_bases
ATGGAAAAACTAAATCCTTACTTTGGTCAATTTGGTGGTATGTTTGTACCCCAAATTCTGGTCCCCGCATTAAAACAGTT
AGAAGCTGAATTTGTAAGAGCGCAAACAGATCCTGAATTTTTAGCAGAGTTATCTGAATTATTAACCGAATATGCAGGTC
GCCCGACGCCCTTAACATTATGTCGCAACCTGACTAAAGGTAAAAAAACCAAACTTTACCTTAAACGCGAAGATCTGCTC
CACGGAGGTGCACATAAAACCAACCAAGTTTTAGGGCAGGCATTACTCGCTAAACGCATGGGTAAAAAAGAAATTATTGC
AGAAACGGGTGCCGGCCAACACGGTGTTGCAGCGGCATTAGCTTGTGCATTACTTGGACTTAAATGTCGTGTTTATATGG
GTGCTGTGGATTGTGAACGTCAAAAACCCAATGTCTTCCGTATGCGTTTAATGGGCGCGGAAGTGATTCCCGTTCATTCC
GGTTCATCAACATTAAAAGATGCCTGTAATGAAGCATTGCGTGATTGGGCTGGCAGTTATGATACTGCGCACTATTTATT
AGGGACAGTGGCCGGCCCACACCCTTTTCCAACGATTGTACGTGAATTCCAGAAAATAATTGGTGAAGAAGCGAAGCAGC
AGGTATTAAAAAAAGAAGGTGTGCTACCTGATAAAGTGATTGCCTGTGTCGGCGGGGGCTCTAACGCCATCGGTATATTC
AATGATTTTATAGACGATCCAAGCGTTGAACTGATTGGTGTTGAGCCAGGAGGACGCGGTATTGAAACCGGTAAACACGG
TTGCCCTATCACCTATGGTTCAAAAGGTATCTTCTTTGGTATGCATTCCTTAATGATGCAGGATAAACATGGTCAGGTTA
AAGAGTCTTATTCGATCTCTGCCGGACTTGATTTCCCGTCCGTTGGTCCGCAACATGCTCACCTTGCAGAAACGGGACGC
GCCCAATATGTTTACGCTACCGATGACGAAGCGCTAGATGCTTTCCATGAACTCTCTTTAAAAGAAGGTATTATTCCGGC
TCTTGAGTCCGCACACGCATTAGCACATGCCTTAAAACTAATTAAACATGATGATAAGGAGCAAATCATTATTGTTAATT
TATCCGGCCGTGGTGATAAAGATATCTTTACCGTCGCTGAAATTTTTGAAGAAAGAGGAATTCTCTAA

Upstream 100 bases:

>100_bases
ACGCCGCATTTTCAGCAATAAAACATTACCTGCAGCGATAAAATATTATTCATTTATTCTAAGGTGGCATCACCTTGTAT
AAAATAAAAGGTTATTAAAA

Downstream 100 bases:

>100_bases
TGAGCAAACGTTATCAGGCTTTATTTGCCCGTCTTAAAACTGAAAACCAGGGAGCCTTTGTTCCTTTTGTGATGCTTAGT
GATCCCAATCGCGCCCTCTC

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MEKLNPYFGQFGGMFVPQILVPALKQLEAEFVRAQTDPEFLAELSELLTEYAGRPTPLTLCRNLTKGKKTKLYLKREDLL
HGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVAAALACALLGLKCRVYMGAVDCERQKPNVFRMRLMGAEVIPVHS
GSSTLKDACNEALRDWAGSYDTAHYLLGTVAGPHPFPTIVREFQKIIGEEAKQQVLKKEGVLPDKVIACVGGGSNAIGIF
NDFIDDPSVELIGVEPGGRGIETGKHGCPITYGSKGIFFGMHSLMMQDKHGQVKESYSISAGLDFPSVGPQHAHLAETGR
AQYVYATDDEALDAFHELSLKEGIIPALESAHALAHALKLIKHDDKEQIIIVNLSGRGDKDIFTVAEIFEERGIL

Sequences:

>Translated_395_residues
MEKLNPYFGQFGGMFVPQILVPALKQLEAEFVRAQTDPEFLAELSELLTEYAGRPTPLTLCRNLTKGKKTKLYLKREDLL
HGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVAAALACALLGLKCRVYMGAVDCERQKPNVFRMRLMGAEVIPVHS
GSSTLKDACNEALRDWAGSYDTAHYLLGTVAGPHPFPTIVREFQKIIGEEAKQQVLKKEGVLPDKVIACVGGGSNAIGIF
NDFIDDPSVELIGVEPGGRGIETGKHGCPITYGSKGIFFGMHSLMMQDKHGQVKESYSISAGLDFPSVGPQHAHLAETGR
AQYVYATDDEALDAFHELSLKEGIIPALESAHALAHALKLIKHDDKEQIIIVNLSGRGDKDIFTVAEIFEERGIL
>Mature_395_residues
MEKLNPYFGQFGGMFVPQILVPALKQLEAEFVRAQTDPEFLAELSELLTEYAGRPTPLTLCRNLTKGKKTKLYLKREDLL
HGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVAAALACALLGLKCRVYMGAVDCERQKPNVFRMRLMGAEVIPVHS
GSSTLKDACNEALRDWAGSYDTAHYLLGTVAGPHPFPTIVREFQKIIGEEAKQQVLKKEGVLPDKVIACVGGGSNAIGIF
NDFIDDPSVELIGVEPGGRGIETGKHGCPITYGSKGIFFGMHSLMMQDKHGQVKESYSISAGLDFPSVGPQHAHLAETGR
AQYVYATDDEALDAFHELSLKEGIIPALESAHALAHALKLIKHDDKEQIIIVNLSGRGDKDIFTVAEIFEERGIL

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family

Homologues:

Organism=Escherichia coli, GI1787515, Length=391, Percent_Identity=75.7033248081841, Blast_Score=624, Evalue=1e-180,
Organism=Saccharomyces cerevisiae, GI6321412, Length=388, Percent_Identity=51.0309278350515, Blast_Score=398, Evalue=1e-112,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPB_PSYIN (A1STT0)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_942494.1
- ProteinModelPortal:   A1STT0
- SMR:   A1STT0
- STRING:   A1STT0
- GeneID:   4625984
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_1056
- eggNOG:   COG0133
- HOGENOM:   HBG303148
- OMA:   LKREDLC
- PhylomeDB:   A1STT0
- ProtClustDB:   PRK04346
- BioCyc:   PING357804:PING_1056-MONOMER
- HAMAP:   MF_00133
- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026
- TIGRFAMs:   TIGR00263

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.2.1.20

Molecular weight: Translated: 42925; Mature: 42925

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLNPYFGQFGGMFVPQILVPALKQLEAEFVRAQTDPEFLAELSELLTEYAGRPTPLTL
CCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHH
CRNLTKGKKTKLYLKREDLLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVAAAL
HHHHCCCCCEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHH
ACALLGLKCRVYMGAVDCERQKPNVFRMRLMGAEVIPVHSGSSTLKDACNEALRDWAGSY
HHHHHHHHHHEEECCCCCCCCCCCCEEHEECCCEEEEECCCCHHHHHHHHHHHHHHCCCC
DTAHYLLGTVAGPHPFPTIVREFQKIIGEEAKQQVLKKEGVLPDKVIACVGGGSNAIGIF
CHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEECCCCCEEHHH
NDFIDDPSVELIGVEPGGRGIETGKHGCPITYGSKGIFFGMHSLMMQDKHGQVKESYSIS
HHHCCCCCEEEEEECCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHCCCCCCHHHCCEEE
AGLDFPSVGPQHAHLAETGRAQYVYATDDEALDAFHELSLKEGIIPALESAHALAHALKL
CCCCCCCCCCCHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
IKHDDKEQIIIVNLSGRGDKDIFTVAEIFEERGIL
HHCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEKLNPYFGQFGGMFVPQILVPALKQLEAEFVRAQTDPEFLAELSELLTEYAGRPTPLTL
CCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHH
CRNLTKGKKTKLYLKREDLLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVAAAL
HHHHCCCCCEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHH
ACALLGLKCRVYMGAVDCERQKPNVFRMRLMGAEVIPVHSGSSTLKDACNEALRDWAGSY
HHHHHHHHHHEEECCCCCCCCCCCCEEHEECCCEEEEECCCCHHHHHHHHHHHHHHCCCC
DTAHYLLGTVAGPHPFPTIVREFQKIIGEEAKQQVLKKEGVLPDKVIACVGGGSNAIGIF
CHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEECCCCCEEHHH
NDFIDDPSVELIGVEPGGRGIETGKHGCPITYGSKGIFFGMHSLMMQDKHGQVKESYSIS
HHHCCCCCEEEEEECCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHCCCCCCHHHCCEEE
AGLDFPSVGPQHAHLAETGRAQYVYATDDEALDAFHELSLKEGIIPALESAHALAHALKL
CCCCCCCCCCCHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
IKHDDKEQIIIVNLSGRGDKDIFTVAEIFEERGIL
HHCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA