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The map label for this gene is surA [H]

Identifier: 119944807

GI number: 119944807

Start: 1321712

End: 1323031

Strand: Reverse

Name: surA [H]

Synonym: Ping_1049

Alternate gene names: 119944807

Gene position: 1323031-1321712 (Counterclockwise)

Preceding gene: 119944808

Following gene: 119944806

Centisome position: 29.02

GC content: 40.53

Gene sequence:

>1320_bases
ATGAAAGTTATCAAGAATATTCTCCTGCCTTTACTTTTTGCGTCTTTGGCCGCAACGCAGGTGTTTGCGGAAAAGATACC
GTTAGACAAAATAGAAGCAGTTGTTAATCAAGAAATTATTCTAAGCAGTGATTTGCAGCGCGCACAACTTGACATTCAAG
AGCGTTATAAAAATAGCGATCAAACATTACCCAGTGGCGATAAATTAACCAAGCAGATTCTTGATAAATTAATCACTGAC
CGTTTACAGCTGCAAATTGCACAACGCATCGGATTACGAATAAACGATGCGCAACTGCAACAAACGGTACAGCAAATAGC
TCAAAAAGAGGGGCTTACCAGTGAACAGCTACAAGCAAAACTTGAAAAACAGGGCAAAAATTACGCTGCCTTTGTTGATA
CTATTCGTGACGAATTGACCATCAATGAAATTCGTCAAATTGAGGTTCGCCGCCGTATAACGATTTCGGATCAAGACGTT
GAACAGATGGTAAAACGGATCAATGCTGAGGGACAAAAAAACACCCAATTTAGTTTTGTACATCTTCTTTTTAAGTTAGA
CAAAGAGAGTTCAGCGGCAGAGCAACAACGTATTGAAAAAAAGGCACAGGATCTGGTTAAAAAAATCAAACTCGGGGCCA
ATGCTTCACAGTTAGCACTGCTTAACTCGGAAGGGCCAAAAGCGTCTGAAGGAGGTGACTGGGGATGGCGGACGATCAAT
GAAATGCCCACTTTATTTGCAGGCATATTTAATGAGCAGCAAACTAATAAAGGGGATGTAATAGGTCCCTTTAAGTCAGA
CCTTGGCCTTCATATTATAAAGATAATGGATAAAAAAGGAGCTCAAAATGTGATGACGGTTGAAGTCAATGCACGACATA
TATTGATTAAATCTAATATCATTCTGAGCGATCAAAAAGCACAAAAATTATTGACGGGTTACCGTCAGGATATTATCAAC
GGCAAAAAATCCTTTGCAGCACTTGCCCGCGAATATTCTCAGGATCCAGGTTCAGCCGTTAAAGGAGGAGATTTAGGTTG
GGCAGATCCCAGTATGTATGTGCCTGAGTTTAAAGAATTAGCGCTCTCTCTGCCCGTTGGAGAAATCAGCCAGCCGTTTC
GTACTATGCATGGTTGGCACATCCTCGAGGTCATAAATAAACGCGAATCAGACACCACAGAACAGGCGACTAAACAAAAA
GCTTACAGCCTGTTATTTCAACAGCGTTTTCCCGCAGAAGTTTACGCCTGGATGAATGAAATACGTCAGGAAGCCTATAT
TAAAATACATAATCCGAATTATATGATTGAGAAAAAATAA

Upstream 100 bases:

>100_bases
AATTTTGAACTGACCGGATTAGGTGGTGTTGGATTTAGCTCTGGTAATCAAAGTTTATTTGATTACGGTCGTCCTTTTTA
CTTACAATAATGGAAAAAAA

Downstream 100 bases:

>100_bases
TGGTAAAGCGTTTAATTATCACTGCCGGAGAACCGGGCGGTATTGGCCCAGACTTAATTCTACAACTTGCTAAACAAGTC
TGGCCTGTGGAATTAATTAT

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MKVIKNILLPLLFASLAATQVFAEKIPLDKIEAVVNQEIILSSDLQRAQLDIQERYKNSDQTLPSGDKLTKQILDKLITD
RLQLQIAQRIGLRINDAQLQQTVQQIAQKEGLTSEQLQAKLEKQGKNYAAFVDTIRDELTINEIRQIEVRRRITISDQDV
EQMVKRINAEGQKNTQFSFVHLLFKLDKESSAAEQQRIEKKAQDLVKKIKLGANASQLALLNSEGPKASEGGDWGWRTIN
EMPTLFAGIFNEQQTNKGDVIGPFKSDLGLHIIKIMDKKGAQNVMTVEVNARHILIKSNIILSDQKAQKLLTGYRQDIIN
GKKSFAALAREYSQDPGSAVKGGDLGWADPSMYVPEFKELALSLPVGEISQPFRTMHGWHILEVINKRESDTTEQATKQK
AYSLLFQQRFPAEVYAWMNEIRQEAYIKIHNPNYMIEKK

Sequences:

>Translated_439_residues
MKVIKNILLPLLFASLAATQVFAEKIPLDKIEAVVNQEIILSSDLQRAQLDIQERYKNSDQTLPSGDKLTKQILDKLITD
RLQLQIAQRIGLRINDAQLQQTVQQIAQKEGLTSEQLQAKLEKQGKNYAAFVDTIRDELTINEIRQIEVRRRITISDQDV
EQMVKRINAEGQKNTQFSFVHLLFKLDKESSAAEQQRIEKKAQDLVKKIKLGANASQLALLNSEGPKASEGGDWGWRTIN
EMPTLFAGIFNEQQTNKGDVIGPFKSDLGLHIIKIMDKKGAQNVMTVEVNARHILIKSNIILSDQKAQKLLTGYRQDIIN
GKKSFAALAREYSQDPGSAVKGGDLGWADPSMYVPEFKELALSLPVGEISQPFRTMHGWHILEVINKRESDTTEQATKQK
AYSLLFQQRFPAEVYAWMNEIRQEAYIKIHNPNYMIEKK
>Mature_439_residues
MKVIKNILLPLLFASLAATQVFAEKIPLDKIEAVVNQEIILSSDLQRAQLDIQERYKNSDQTLPSGDKLTKQILDKLITD
RLQLQIAQRIGLRINDAQLQQTVQQIAQKEGLTSEQLQAKLEKQGKNYAAFVDTIRDELTINEIRQIEVRRRITISDQDV
EQMVKRINAEGQKNTQFSFVHLLFKLDKESSAAEQQRIEKKAQDLVKKIKLGANASQLALLNSEGPKASEGGDWGWRTIN
EMPTLFAGIFNEQQTNKGDVIGPFKSDLGLHIIKIMDKKGAQNVMTVEVNARHILIKSNIILSDQKAQKLLTGYRQDIIN
GKKSFAALAREYSQDPGSAVKGGDLGWADPSMYVPEFKELALSLPVGEISQPFRTMHGWHILEVINKRESDTTEQATKQK
AYSLLFQQRFPAEVYAWMNEIRQEAYIKIHNPNYMIEKK

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=427, Percent_Identity=37.0023419203747, Blast_Score=298, Evalue=4e-82,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 49822; Mature: 49822

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVIKNILLPLLFASLAATQVFAEKIPLDKIEAVVNQEIILSSDLQRAQLDIQERYKNSD
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHCCHHHHHHHHHHHHCCCC
QTLPSGDKLTKQILDKLITDRLQLQIAQRIGLRINDAQLQQTVQQIAQKEGLTSEQLQAK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
LEKQGKNYAAFVDTIRDELTINEIRQIEVRRRITISDQDVEQMVKRINAEGQKNTQFSFV
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHCCCCCCCCHHHHH
HLLFKLDKESSAAEQQRIEKKAQDLVKKIKLGANASQLALLNSEGPKASEGGDWGWRTIN
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEECCCCCCCCCCCCCHHHHH
EMPTLFAGIFNEQQTNKGDVIGPFKSDLGLHIIKIMDKKGAQNVMTVEVNARHILIKSNI
HHHHHHHHHHCCCCCCCCCCCCCCHHCCCHHHHHHHCCCCCCCEEEEEECCEEEEEECCE
ILSDQKAQKLLTGYRQDIINGKKSFAALAREYSQDPGSAVKGGDLGWADPSMYVPEFKEL
EECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHH
ALSLPVGEISQPFRTMHGWHILEVINKRESDTTEQATKQKAYSLLFQQRFPAEVYAWMNE
HHHCCHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
IRQEAYIKIHNPNYMIEKK
HHHHHEEEECCCCEEEECC
>Mature Secondary Structure
MKVIKNILLPLLFASLAATQVFAEKIPLDKIEAVVNQEIILSSDLQRAQLDIQERYKNSD
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHCCHHHHHHHHHHHHCCCC
QTLPSGDKLTKQILDKLITDRLQLQIAQRIGLRINDAQLQQTVQQIAQKEGLTSEQLQAK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
LEKQGKNYAAFVDTIRDELTINEIRQIEVRRRITISDQDVEQMVKRINAEGQKNTQFSFV
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHCCCCCCCCHHHHH
HLLFKLDKESSAAEQQRIEKKAQDLVKKIKLGANASQLALLNSEGPKASEGGDWGWRTIN
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEECCCCCCCCCCCCCHHHHH
EMPTLFAGIFNEQQTNKGDVIGPFKSDLGLHIIKIMDKKGAQNVMTVEVNARHILIKSNI
HHHHHHHHHHCCCCCCCCCCCCCCHHCCCHHHHHHHCCCCCCCEEEEEECCEEEEEECCE
ILSDQKAQKLLTGYRQDIINGKKSFAALAREYSQDPGSAVKGGDLGWADPSMYVPEFKEL
EECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHH
ALSLPVGEISQPFRTMHGWHILEVINKRESDTTEQATKQKAYSLLFQQRFPAEVYAWMNE
HHHCCHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
IRQEAYIKIHNPNYMIEKK
HHHHHEEEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA