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The map label for this gene is ptrB [H]

Identifier: 119944405

GI number: 119944405

Start: 813765

End: 815858

Strand: Direct

Name: ptrB [H]

Synonym: Ping_0633

Alternate gene names: 119944405

Gene position: 813765-815858 (Clockwise)

Preceding gene: 119944404

Following gene: 119944406

Centisome position: 17.85

GC content: 41.21

Gene sequence:

>2094_bases
ATGCTAATATTGTCACACTTACAACAAGCAGAGAAAATCATGAATTTAAAACTTAAACTGTCAGCCCCCCAAGCGCTAAA
AAAAAACCACATTCATGAAATTCATGGTGATTTACGTCAAGATGATTATTTTTGGTTGCGTGATGATCATCGTCAGAATC
AGCAGGTGATCGATTATTTAGAGCAAGAAAATGCCTTTACCGAGCAGGAGATGAGCCCCTTAGCTCCCCTGCAGACTGAG
TTGTATGACGAGATGGTGGCACGGCAGGAGCCTGAGCTTGAATCTGTTCCTTATTTTAAACAAGGGTTTTGGTATACCGT
CCGCTTTGCAGAAGGCAAAGATTATATGGTTTATAGCCGTAGAAAAGAATCGATGGCGGCCTCAGAGCAGATACTTGTCG
ATTGCAATGAACGTGCACAGGGGCTTTCGTATTATCAATTGGGTGATGTGACCCTATCAAGTAATTCAATGTTGATGGCA
TTCTCCGAAGATGTGGTTGGTCGCCGTCAATATACCTTAGGTTTTAAAAATCTTGAGACAGGTGAGATTCTAAATGATCT
TATTGAAGATGTTTCTGACGTGGTCTGGGCAAATGATAATCAAACCGTTTTTTATGTTAAACAACACCCGGAAACCTTAT
TACCCTACCAGGTATACCGCCACAGATTAGGTGACAGAATAAAGGATGACGTATTAGTTTATGAAGAGCTGGATGATACC
TTCTACGTGAGTCTTGACAAAACACGTTCCGAGCAGTATCTGGTTATTGCCATTGACAGTACCACCACCTCTGAATGTTT
AGTGTTAGATGCTGATCAGCCGATGGGAGAGTTTGTCTCATTTTTACCCCGGTTACGCGGGCATGAATACAGTATTGATC
ATTTCCAGGAACAGTTTTATATTCGCACCAATAACAGTGGTAAAAACTTTGCTTTAAAAACATCGACTTTACTGATCAAT
CACAATGCAGATGCTTGGGTTACTATTATTGAAGCGCGTAACGATGTGCTGTTGGAAGGTTATGAATTGATGAAGGAGTG
GTTAATTGTTGAAGAGCGTCAAGATGGTTTACCCCTGTTACGGCAGATTAATCATCAAACCGGTGAGTCAAAAACCTTAA
CGTTTAGTGATCCTGTCTATACCGTTTTTAGTCATTTTAATCCTGAAGCTAATACAGCTAAATTTCGCTATCAATATACC
TCATTTACCACTCCCTCATCGGTCTATGAATTGGATTTAAACAGCGGTGAAACCATTCTATTAAAACAAAGCCAAGTAAT
GGGCGAGTTTGACAGTCATGACTATAAAAGCGAACGTGTTTGGGTCACCGCGCGTGATGGTGTACAGGTTCCTGTTTCTC
TGGTTTATAGTAAAAAATTGTTTAATCACGAAAATCCAATACTTATTTATGCCTATGGCTCTTATGGCCATAGTTTAGAT
ATTGGTTTTGATTCTTCAAACTTAAGTCTTCTGGATCGCGGTTTTGTGTATGCCATTGCACATATTCGAGGTGGAGAAGA
GTTAGGACGGTCTTGGTATGAAGAGGGGAAGTTGCTTAAGAAACAAAATACCTTTAATGATTTTATTGATGTAACGAAAA
GCCTAATCAGCACTGGTTACGGGTCAGAGGAGAAGGTCTTTGCGATGGGCGGAAGCGCGGGGGGATTATTGATGGGGGCA
ATAATTAACCAGGCACCGGAATTATATAAAGGGGTGGTGGCAGTGGTGCCCTTTGTTGACATAGTATCAACGATGTTAGA
CGAATCCATTCCGCTGACCACGGGGGAATATGATGAGTGGGGTAATCCAAATGAAAAAAATTATTATCACTATATGCTTT
CCTATAGCCCCTACGATCAAGTGAAAGCCGTGGACTATCCTAATATGTTGGTGACCACCGGCTTACATGATTCACAGGTG
CAATATTGGGAACCTGCCAAGTGGGTGGCTAAATTGCGCGCCTTAAAGACGGATCACAACCAATTACTTTTATATACGGA
TATGGAAGCCGGACACGGTGGTAAATCGGGTCGCTTTAAACACTTTGAGGATACCGCCAGAGAATTTGCCTTTATTCTTT
CTTTAGTGAAATAA

Upstream 100 bases:

>100_bases
TGTAGTGTTATTAGGCTGTTATCTTTGATGATTAATTCCTTTTCTATAATGCTGCCTGAATGGTCTATCTCAACGGCAAC
CTTTCCCCAAACTCGGCTCA

Downstream 100 bases:

>100_bases
ACGCCGCAGTGTGAGCTTGCATTCTTTGCCGTAGTGGTCAGATTAACTGCGCTGCTGCCGCTGCAACAGTATTATTTATA
ACTGGCAATCAGGGGCAATA

Product: oligopeptidase B

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 697; Mature: 697

Protein sequence:

>697_residues
MLILSHLQQAEKIMNLKLKLSAPQALKKNHIHEIHGDLRQDDYFWLRDDHRQNQQVIDYLEQENAFTEQEMSPLAPLQTE
LYDEMVARQEPELESVPYFKQGFWYTVRFAEGKDYMVYSRRKESMAASEQILVDCNERAQGLSYYQLGDVTLSSNSMLMA
FSEDVVGRRQYTLGFKNLETGEILNDLIEDVSDVVWANDNQTVFYVKQHPETLLPYQVYRHRLGDRIKDDVLVYEELDDT
FYVSLDKTRSEQYLVIAIDSTTTSECLVLDADQPMGEFVSFLPRLRGHEYSIDHFQEQFYIRTNNSGKNFALKTSTLLIN
HNADAWVTIIEARNDVLLEGYELMKEWLIVEERQDGLPLLRQINHQTGESKTLTFSDPVYTVFSHFNPEANTAKFRYQYT
SFTTPSSVYELDLNSGETILLKQSQVMGEFDSHDYKSERVWVTARDGVQVPVSLVYSKKLFNHENPILIYAYGSYGHSLD
IGFDSSNLSLLDRGFVYAIAHIRGGEELGRSWYEEGKLLKKQNTFNDFIDVTKSLISTGYGSEEKVFAMGGSAGGLLMGA
IINQAPELYKGVVAVVPFVDIVSTMLDESIPLTTGEYDEWGNPNEKNYYHYMLSYSPYDQVKAVDYPNMLVTTGLHDSQV
QYWEPAKWVAKLRALKTDHNQLLLYTDMEAGHGGKSGRFKHFEDTAREFAFILSLVK

Sequences:

>Translated_697_residues
MLILSHLQQAEKIMNLKLKLSAPQALKKNHIHEIHGDLRQDDYFWLRDDHRQNQQVIDYLEQENAFTEQEMSPLAPLQTE
LYDEMVARQEPELESVPYFKQGFWYTVRFAEGKDYMVYSRRKESMAASEQILVDCNERAQGLSYYQLGDVTLSSNSMLMA
FSEDVVGRRQYTLGFKNLETGEILNDLIEDVSDVVWANDNQTVFYVKQHPETLLPYQVYRHRLGDRIKDDVLVYEELDDT
FYVSLDKTRSEQYLVIAIDSTTTSECLVLDADQPMGEFVSFLPRLRGHEYSIDHFQEQFYIRTNNSGKNFALKTSTLLIN
HNADAWVTIIEARNDVLLEGYELMKEWLIVEERQDGLPLLRQINHQTGESKTLTFSDPVYTVFSHFNPEANTAKFRYQYT
SFTTPSSVYELDLNSGETILLKQSQVMGEFDSHDYKSERVWVTARDGVQVPVSLVYSKKLFNHENPILIYAYGSYGHSLD
IGFDSSNLSLLDRGFVYAIAHIRGGEELGRSWYEEGKLLKKQNTFNDFIDVTKSLISTGYGSEEKVFAMGGSAGGLLMGA
IINQAPELYKGVVAVVPFVDIVSTMLDESIPLTTGEYDEWGNPNEKNYYHYMLSYSPYDQVKAVDYPNMLVTTGLHDSQV
QYWEPAKWVAKLRALKTDHNQLLLYTDMEAGHGGKSGRFKHFEDTAREFAFILSLVK
>Mature_697_residues
MLILSHLQQAEKIMNLKLKLSAPQALKKNHIHEIHGDLRQDDYFWLRDDHRQNQQVIDYLEQENAFTEQEMSPLAPLQTE
LYDEMVARQEPELESVPYFKQGFWYTVRFAEGKDYMVYSRRKESMAASEQILVDCNERAQGLSYYQLGDVTLSSNSMLMA
FSEDVVGRRQYTLGFKNLETGEILNDLIEDVSDVVWANDNQTVFYVKQHPETLLPYQVYRHRLGDRIKDDVLVYEELDDT
FYVSLDKTRSEQYLVIAIDSTTTSECLVLDADQPMGEFVSFLPRLRGHEYSIDHFQEQFYIRTNNSGKNFALKTSTLLIN
HNADAWVTIIEARNDVLLEGYELMKEWLIVEERQDGLPLLRQINHQTGESKTLTFSDPVYTVFSHFNPEANTAKFRYQYT
SFTTPSSVYELDLNSGETILLKQSQVMGEFDSHDYKSERVWVTARDGVQVPVSLVYSKKLFNHENPILIYAYGSYGHSLD
IGFDSSNLSLLDRGFVYAIAHIRGGEELGRSWYEEGKLLKKQNTFNDFIDVTKSLISTGYGSEEKVFAMGGSAGGLLMGA
IINQAPELYKGVVAVVPFVDIVSTMLDESIPLTTGEYDEWGNPNEKNYYHYMLSYSPYDQVKAVDYPNMLVTTGLHDSQV
QYWEPAKWVAKLRALKTDHNQLLLYTDMEAGHGGKSGRFKHFEDTAREFAFILSLVK

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=721, Percent_Identity=25.3814147018031, Blast_Score=193, Evalue=4e-49,
Organism=Homo sapiens, GI284172420, Length=488, Percent_Identity=26.6393442622951, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI284172413, Length=488, Percent_Identity=26.6393442622951, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI70778815, Length=488, Percent_Identity=26.6393442622951, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI284172438, Length=490, Percent_Identity=26.530612244898, Blast_Score=168, Evalue=2e-41,
Organism=Homo sapiens, GI284172431, Length=490, Percent_Identity=26.530612244898, Blast_Score=168, Evalue=2e-41,
Organism=Homo sapiens, GI108860686, Length=477, Percent_Identity=24.7379454926625, Blast_Score=140, Evalue=6e-33,
Organism=Homo sapiens, GI108860692, Length=471, Percent_Identity=26.5392781316348, Blast_Score=135, Evalue=9e-32,
Organism=Escherichia coli, GI1788150, Length=682, Percent_Identity=52.1994134897361, Blast_Score=734, Evalue=0.0,
Organism=Drosophila melanogaster, GI24583414, Length=740, Percent_Identity=25.4054054054054, Blast_Score=188, Evalue=1e-47,
Organism=Drosophila melanogaster, GI221510989, Length=728, Percent_Identity=24.8626373626374, Blast_Score=172, Evalue=8e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 80209; Mature: 80209

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLILSHLQQAEKIMNLKLKLSAPQALKKNHIHEIHGDLRQDDYFWLRDDHRQNQQVIDYL
CEEHHHHHHHHHHHCEEEEECCCHHHHHCCHHHHHCCCCCCCEEEEECCCCCCHHHHHHH
EQENAFTEQEMSPLAPLQTELYDEMVARQEPELESVPYFKQGFWYTVRFAEGKDYMVYSR
HHCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHCCCEEEEEEECCCCEEEEEC
RKESMAASEQILVDCNERAQGLSYYQLGDVTLSSNSMLMAFSEDVVGRRQYTLGFKNLET
HHHHHHCCCEEEEECCCCCCCCCEEEECCEEECCCCEEEEECCCCCCCEEEEECCCCCCH
GEILNDLIEDVSDVVWANDNQTVFYVKQHPETLLPYQVYRHRLGDRIKDDVLVYEELDDT
HHHHHHHHHHHHHHEEECCCCEEEEEECCCCCCCCHHHHHHHHCCCHHCCEEEEEECCCE
FYVSLDKTRSEQYLVIAIDSTTTSECLVLDADQPMGEFVSFLPRLRGHEYSIDHFQEQFY
EEEEEECCCCCCEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCHHHHCEEEE
IRTNNSGKNFALKTSTLLINHNADAWVTIIEARNDVLLEGYELMKEWLIVEERQDGLPLL
EEECCCCCEEEEEEEEEEEECCCCEEEEEEECCCCEEEHHHHHHHHHHEEECCCCCCHHH
RQINHQTGESKTLTFSDPVYTVFSHFNPEANTAKFRYQYTSFTTPSSVYELDLNSGETIL
HHHCCCCCCCCEEEECCCHHHHHHHCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCEEE
LKQSQVMGEFDSHDYKSERVWVTARDGVQVPVSLVYSKKLFNHENPILIYAYGSYGHSLD
EECHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCEEE
IGFDSSNLSLLDRGFVYAIAHIRGGEELGRSWYEEGKLLKKQNTFNDFIDVTKSLISTGY
EEECCCCCHHHHCCEEEEEEEECCCHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHCCC
GSEEKVFAMGGSAGGLLMGAIINQAPELYKGVVAVVPFVDIVSTMLDESIPLTTGEYDEW
CCCCEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GNPNEKNYYHYMLSYSPYDQVKAVDYPNMLVTTGLHDSQVQYWEPAKWVAKLRALKTDHN
CCCCCCCEEEEEEEECCCCCEEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCC
QLLLYTDMEAGHGGKSGRFKHFEDTAREFAFILSLVK
EEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLILSHLQQAEKIMNLKLKLSAPQALKKNHIHEIHGDLRQDDYFWLRDDHRQNQQVIDYL
CEEHHHHHHHHHHHCEEEEECCCHHHHHCCHHHHHCCCCCCCEEEEECCCCCCHHHHHHH
EQENAFTEQEMSPLAPLQTELYDEMVARQEPELESVPYFKQGFWYTVRFAEGKDYMVYSR
HHCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHCCCEEEEEEECCCCEEEEEC
RKESMAASEQILVDCNERAQGLSYYQLGDVTLSSNSMLMAFSEDVVGRRQYTLGFKNLET
HHHHHHCCCEEEEECCCCCCCCCEEEECCEEECCCCEEEEECCCCCCCEEEEECCCCCCH
GEILNDLIEDVSDVVWANDNQTVFYVKQHPETLLPYQVYRHRLGDRIKDDVLVYEELDDT
HHHHHHHHHHHHHHEEECCCCEEEEEECCCCCCCCHHHHHHHHCCCHHCCEEEEEECCCE
FYVSLDKTRSEQYLVIAIDSTTTSECLVLDADQPMGEFVSFLPRLRGHEYSIDHFQEQFY
EEEEEECCCCCCEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCHHHHCEEEE
IRTNNSGKNFALKTSTLLINHNADAWVTIIEARNDVLLEGYELMKEWLIVEERQDGLPLL
EEECCCCCEEEEEEEEEEEECCCCEEEEEEECCCCEEEHHHHHHHHHHEEECCCCCCHHH
RQINHQTGESKTLTFSDPVYTVFSHFNPEANTAKFRYQYTSFTTPSSVYELDLNSGETIL
HHHCCCCCCCCEEEECCCHHHHHHHCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCEEE
LKQSQVMGEFDSHDYKSERVWVTARDGVQVPVSLVYSKKLFNHENPILIYAYGSYGHSLD
EECHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCEEE
IGFDSSNLSLLDRGFVYAIAHIRGGEELGRSWYEEGKLLKKQNTFNDFIDVTKSLISTGY
EEECCCCCHHHHCCEEEEEEEECCCHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHCCC
GSEEKVFAMGGSAGGLLMGAIINQAPELYKGVVAVVPFVDIVSTMLDESIPLTTGEYDEW
CCCCEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GNPNEKNYYHYMLSYSPYDQVKAVDYPNMLVTTGLHDSQVQYWEPAKWVAKLRALKTDHN
CCCCCCCEEEEEEEECCCCCEEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCC
QLLLYTDMEAGHGGKSGRFKHFEDTAREFAFILSLVK
EEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1769955; 9097040; 9278503 [H]