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The map label for this gene is galR [H]

Identifier: 119944325

GI number: 119944325

Start: 706053

End: 707057

Strand: Reverse

Name: galR [H]

Synonym: Ping_0552

Alternate gene names: 119944325

Gene position: 707057-706053 (Counterclockwise)

Preceding gene: 119944327

Following gene: 119944316

Centisome position: 15.51

GC content: 41.49

Gene sequence:

>1005_bases
ATGACGTTGATCACGATTAAAGAGGTATCCGATCTTGCGCAGGTCTCTCAGGCAACAGTATCAAGAGCCATCAATGGGCA
CCCAACTGTTAAAGAGAGCAATAAGCTCAAGGTGTTTGAAGCAATCAAAAAACTTGGTTATAAACCTAACTCTTTCGCAC
AGGCACTGGCGTCCAACCGTTCAAATAGCATCGGTATGCTGGTTGGTACACTCGATGGCCCCTTCTTTGGTCCTTTAATG
CATAATGCAGAAAATATTATTCGTCAGAAAAATATGCATTTAATTGTCACCAGCGGCCAGGAGTCGAGAACCAAGGAAGT
CGATTCTATTGCATTTCTCCAGTCTAAACAGGTTGATGGTATGATTATCCATTCAGATAAATTAACCGATCAAGAATTAA
TAACCATCGCGCAAAAAAATCCTGCAATGGTTATTTTAAACCGCTATATTCCGGAATTAGATAAACAGTGTATCTGCATA
GATAATGAACTGGGCGGATACCTGGCAACAAAATATTTACTTGAAAATGGACATACAAAAGTAGGCTGTATTACAGGTCA
AATGAGTAAAATTGACAGCCGTGATCGCTTTCAGGGATACAGAAATGCGCTGGCGGAGTTTTCTATCCCCTACGATACTA
ATCTGGTTATTGAAGGGCGTTTTGATCATCAGGGCAATCACGAGGTGGTCAGAAGATTGCTCAGCCGTGATAATGGAATA
ACCGCTATTTTCTGTGAGAACGATAATATCGCCCTGGCAGCTTATGATATCTGCAACGAAAAAAACTTGTCCGTAGGTGA
TGATATTTCCATTGTTGGTTTTGATAACGATACCTACAGCCAGCATATCCGTCCCAGACTGTCGACGGTCAACTTCCCCG
TTGTTGACATGGGTCTGGAAGCGGCACACGCGGTGCTCGCGATGATCGATAAAAAAAGCTATCCATTCAAAAAAAGATTG
GTGCCTGAATTAGTCATCAGAGATTCGGTAAAAAAAATAAAATAA

Upstream 100 bases:

>100_bases
TATATCATTCACACGCGATATAAAACGGCATAATAAGACAGCTCCTTATTGGAATAAATAATTATGCTTCAATTAATAGA
TAGATATTTTTGGTAAGGTA

Downstream 100 bases:

>100_bases
AGATAGCAGTACGATAACGGAGTATTAACGACGTGAATACTCCGTTTCGCCCTGCATTCTAGAAACAGTTAACTATCATT
TGGACAATAACAGTGTAGAT

Product: transcriptional regulator for galactose, periplasmic binding protein, LacI family protein

Products: NA

Alternate protein names: Galactose operon repressor [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTLITIKEVSDLAQVSQATVSRAINGHPTVKESNKLKVFEAIKKLGYKPNSFAQALASNRSNSIGMLVGTLDGPFFGPLM
HNAENIIRQKNMHLIVTSGQESRTKEVDSIAFLQSKQVDGMIIHSDKLTDQELITIAQKNPAMVILNRYIPELDKQCICI
DNELGGYLATKYLLENGHTKVGCITGQMSKIDSRDRFQGYRNALAEFSIPYDTNLVIEGRFDHQGNHEVVRRLLSRDNGI
TAIFCENDNIALAAYDICNEKNLSVGDDISIVGFDNDTYSQHIRPRLSTVNFPVVDMGLEAAHAVLAMIDKKSYPFKKRL
VPELVIRDSVKKIK

Sequences:

>Translated_334_residues
MTLITIKEVSDLAQVSQATVSRAINGHPTVKESNKLKVFEAIKKLGYKPNSFAQALASNRSNSIGMLVGTLDGPFFGPLM
HNAENIIRQKNMHLIVTSGQESRTKEVDSIAFLQSKQVDGMIIHSDKLTDQELITIAQKNPAMVILNRYIPELDKQCICI
DNELGGYLATKYLLENGHTKVGCITGQMSKIDSRDRFQGYRNALAEFSIPYDTNLVIEGRFDHQGNHEVVRRLLSRDNGI
TAIFCENDNIALAAYDICNEKNLSVGDDISIVGFDNDTYSQHIRPRLSTVNFPVVDMGLEAAHAVLAMIDKKSYPFKKRL
VPELVIRDSVKKIK
>Mature_333_residues
TLITIKEVSDLAQVSQATVSRAINGHPTVKESNKLKVFEAIKKLGYKPNSFAQALASNRSNSIGMLVGTLDGPFFGPLMH
NAENIIRQKNMHLIVTSGQESRTKEVDSIAFLQSKQVDGMIIHSDKLTDQELITIAQKNPAMVILNRYIPELDKQCICID
NELGGYLATKYLLENGHTKVGCITGQMSKIDSRDRFQGYRNALAEFSIPYDTNLVIEGRFDHQGNHEVVRRLLSRDNGIT
AIFCENDNIALAAYDICNEKNLSVGDDISIVGFDNDTYSQHIRPRLSTVNFPVVDMGLEAAHAVLAMIDKKSYPFKKRLV
PELVIRDSVKKIK

Specific function: Repressor of the galactose operon. Binds galactose as an inducer [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789202, Length=330, Percent_Identity=36.0606060606061, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1788474, Length=329, Percent_Identity=31.9148936170213, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1789068, Length=332, Percent_Identity=29.8192771084337, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1787948, Length=331, Percent_Identity=29.0030211480363, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI1790369, Length=333, Percent_Identity=30.3303303303303, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1790194, Length=332, Percent_Identity=31.3253012048193, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1787580, Length=318, Percent_Identity=23.2704402515723, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787906, Length=253, Percent_Identity=27.2727272727273, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1790715, Length=310, Percent_Identity=26.1290322580645, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI48994940, Length=312, Percent_Identity=24.6794871794872, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786540, Length=299, Percent_Identity=28.4280936454849, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1790689, Length=314, Percent_Identity=20.7006369426752, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786268, Length=321, Percent_Identity=20.5607476635514, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1789456, Length=354, Percent_Identity=22.8813559322034, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1790192, Length=228, Percent_Identity=26.3157894736842, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37253; Mature: 37122

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLITIKEVSDLAQVSQATVSRAINGHPTVKESNKLKVFEAIKKLGYKPNSFAQALASNR
CEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHCCC
SNSIGMLVGTLDGPFFGPLMHNAENIIRQKNMHLIVTSGQESRTKEVDSIAFLQSKQVDG
CCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCCE
MIIHSDKLTDQELITIAQKNPAMVILNRYIPELDKQCICIDNELGGYLATKYLLENGHTK
EEEECCCCCCCHHEEEECCCCCEEEEEHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCEE
VGCITGQMSKIDSRDRFQGYRNALAEFSIPYDTNLVIEGRFDHQGNHEVVRRLLSRDNGI
EEEEECCHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCE
TAIFCENDNIALAAYDICNEKNLSVGDDISIVGFDNDTYSQHIRPRLSTVNFPVVDMGLE
EEEEECCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCHHHHCCCHHHCCCCCHHHCCHH
AAHAVLAMIDKKSYPFKKRLVPELVIRDSVKKIK
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLITIKEVSDLAQVSQATVSRAINGHPTVKESNKLKVFEAIKKLGYKPNSFAQALASNR
EEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHCCC
SNSIGMLVGTLDGPFFGPLMHNAENIIRQKNMHLIVTSGQESRTKEVDSIAFLQSKQVDG
CCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCCE
MIIHSDKLTDQELITIAQKNPAMVILNRYIPELDKQCICIDNELGGYLATKYLLENGHTK
EEEECCCCCCCHHEEEECCCCCEEEEEHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCEE
VGCITGQMSKIDSRDRFQGYRNALAEFSIPYDTNLVIEGRFDHQGNHEVVRRLLSRDNGI
EEEEECCHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCE
TAIFCENDNIALAAYDICNEKNLSVGDDISIVGFDNDTYSQHIRPRLSTVNFPVVDMGLE
EEEEECCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCHHHHCCCHHHCCCCCHHHCCHH
AAHAVLAMIDKKSYPFKKRLVPELVIRDSVKKIK
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6283521; 9278503; 6350601; 8188660; 8982002 [H]