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The map label for this gene is appC [H]

Identifier: 119944320

GI number: 119944320

Start: 698882

End: 699865

Strand: Direct

Name: appC [H]

Synonym: Ping_0547

Alternate gene names: 119944320

Gene position: 698882-699865 (Clockwise)

Preceding gene: 119944319

Following gene: 119944321

Centisome position: 15.33

GC content: 43.9

Gene sequence:

>984_bases
ATGAACATCAACAAGACAATCAATACAGATGCGCCTGTTTCTGCTGCTCATACCAGTGAGTTTAGAAAAAAATTTAAATC
TATCATAAAAAAAACCAAAGCTTTTTTTGACGGTAATCCTCCCGCTATTATTGGAGGCTTTTTAATCACTGTTATTTTAC
TTGGTGCTTTATTTGCGCCGCTATTTGCCTCGCATAATCCTGAGAAACGGGTTGCCAGGCCCCATGTTGCGCCTAATGCT
GAACATATAATGGGTACCACGCGAAGTGGACGAGATGTTTATAGTCAGGTTCTTTACGGCGCAAGAAAAACCTTAAGTGT
TGCATTTTTCGCCGGTCTTATTGCCATGTCAATCGCCGTTGCCGTCGGGGTTACATCCGGTTATTTAGGAGGAAAAATTG
ATGAATGGATGAATTTTGTTACTAACGTCTTCCTGGTTTTTCCGCAGCTGCCTTTATTGATTGTACTCGCTGCCTTCTTA
GGGCAGGTCGGCTCAATGGTTATTACCATTCTGTTGGGGCTAACCTCCTGGCCATGGGGAGCAAGGGTGATTCGATCACA
GACGATGGCCCTTCGAAATAAAGAGTTTATTCTTTCAGCTGAAGTCATGGGTGAATCCAAAATTCGTATTATTCTAGTGG
AGATTCTGCCTAATTTAATCTCAATCGTATTTGGTGGATTTCTGGGCACTGTTATCTATGCGATGGGCGCTGAAGCCGGT
CTGGGTATTCTTGGGTTAGGTGATGCAACGGAAGTAAGCTGGGGATCAATGCTCTATTGGGCACAGGTATCCTCTTCTTT
ATATACCGGCGCATGGTGGGAGATGATTGTACCTGCAGCTGCACTGGCGTTAACTGGGGGGGCATTGGCACTGCTCAATA
TGTCAATTGATCAAGTCAGTAACCCGAAACTTAAAACCGGGCCGCATATGAAGTTATGGAAAAAATTAAATAAAGAAGCA
AATCAGCGTCGAGGCCTACTATGA

Upstream 100 bases:

>100_bases
ATTTTACTTATTCTTGTCTCTGCCGTCCTTACCGCAAATTTCATAGCCGATCTGCTTTATGTCTGGCTTGACCCTCGGAT
TTCTAACTAAGGTTTACAAC

Downstream 100 bases:

>100_bases
AAGAAGCACTTTTAGAAATAAATAATCTGTGTGTTGATTATGTTTCTCCAAACGGCATAGCAAGAGCGGTTAATAATGTC
AGCCTCAGTATTGCACCGGG

Product: peptide ABC transporter, protein inner membrane binding component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MNINKTINTDAPVSAAHTSEFRKKFKSIIKKTKAFFDGNPPAIIGGFLITVILLGALFAPLFASHNPEKRVARPHVAPNA
EHIMGTTRSGRDVYSQVLYGARKTLSVAFFAGLIAMSIAVAVGVTSGYLGGKIDEWMNFVTNVFLVFPQLPLLIVLAAFL
GQVGSMVITILLGLTSWPWGARVIRSQTMALRNKEFILSAEVMGESKIRIILVEILPNLISIVFGGFLGTVIYAMGAEAG
LGILGLGDATEVSWGSMLYWAQVSSSLYTGAWWEMIVPAAALALTGGALALLNMSIDQVSNPKLKTGPHMKLWKKLNKEA
NQRRGLL

Sequences:

>Translated_327_residues
MNINKTINTDAPVSAAHTSEFRKKFKSIIKKTKAFFDGNPPAIIGGFLITVILLGALFAPLFASHNPEKRVARPHVAPNA
EHIMGTTRSGRDVYSQVLYGARKTLSVAFFAGLIAMSIAVAVGVTSGYLGGKIDEWMNFVTNVFLVFPQLPLLIVLAAFL
GQVGSMVITILLGLTSWPWGARVIRSQTMALRNKEFILSAEVMGESKIRIILVEILPNLISIVFGGFLGTVIYAMGAEAG
LGILGLGDATEVSWGSMLYWAQVSSSLYTGAWWEMIVPAAALALTGGALALLNMSIDQVSNPKLKTGPHMKLWKKLNKEA
NQRRGLL
>Mature_327_residues
MNINKTINTDAPVSAAHTSEFRKKFKSIIKKTKAFFDGNPPAIIGGFLITVILLGALFAPLFASHNPEKRVARPHVAPNA
EHIMGTTRSGRDVYSQVLYGARKTLSVAFFAGLIAMSIAVAVGVTSGYLGGKIDEWMNFVTNVFLVFPQLPLLIVLAAFL
GQVGSMVITILLGLTSWPWGARVIRSQTMALRNKEFILSAEVMGESKIRIILVEILPNLISIVFGGFLGTVIYAMGAEAG
LGILGLGDATEVSWGSMLYWAQVSSSLYTGAWWEMIVPAAALALTGGALALLNMSIDQVSNPKLKTGPHMKLWKKLNKEA
NQRRGLL

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=267, Percent_Identity=29.2134831460674, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1787760, Length=292, Percent_Identity=27.3972602739726, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787498, Length=282, Percent_Identity=30.4964539007092, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789889, Length=236, Percent_Identity=27.1186440677966, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1789964, Length=313, Percent_Identity=29.7124600638978, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1788505, Length=143, Percent_Identity=31.4685314685315, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787549, Length=273, Percent_Identity=24.1758241758242, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35316; Mature: 35316

Theoretical pI: Translated: 10.55; Mature: 10.55

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNINKTINTDAPVSAAHTSEFRKKFKSIIKKTKAFFDGNPPAIIGGFLITVILLGALFAP
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
LFASHNPEKRVARPHVAPNAEHIMGTTRSGRDVYSQVLYGARKTLSVAFFAGLIAMSIAV
HHHCCCCHHHCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGVTSGYLGGKIDEWMNFVTNVFLVFPQLPLLIVLAAFLGQVGSMVITILLGLTSWPWG
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ARVIRSQTMALRNKEFILSAEVMGESKIRIILVEILPNLISIVFGGFLGTVIYAMGAEAG
HHHHHHHHHHHCCCHHEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LGILGLGDATEVSWGSMLYWAQVSSSLYTGAWWEMIVPAAALALTGGALALLNMSIDQVS
CCEEECCCCCCCCCCHHHHHHHHHCCHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
NPKLKTGPHMKLWKKLNKEANQRRGLL
CCCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNINKTINTDAPVSAAHTSEFRKKFKSIIKKTKAFFDGNPPAIIGGFLITVILLGALFAP
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
LFASHNPEKRVARPHVAPNAEHIMGTTRSGRDVYSQVLYGARKTLSVAFFAGLIAMSIAV
HHHCCCCHHHCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGVTSGYLGGKIDEWMNFVTNVFLVFPQLPLLIVLAAFLGQVGSMVITILLGLTSWPWG
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ARVIRSQTMALRNKEFILSAEVMGESKIRIILVEILPNLISIVFGGFLGTVIYAMGAEAG
HHHHHHHHHHHCCCHHEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LGILGLGDATEVSWGSMLYWAQVSSSLYTGAWWEMIVPAAALALTGGALALLNMSIDQVS
CCEEECCCCCCCCCCHHHHHHHHHCCHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
NPKLKTGPHMKLWKKLNKEANQRRGLL
CCCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]