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The map label for this gene is ptsP [H]

Identifier: 119944277

GI number: 119944277

Start: 637456

End: 639738

Strand: Direct

Name: ptsP [H]

Synonym: Ping_0503

Alternate gene names: 119944277

Gene position: 637456-639738 (Clockwise)

Preceding gene: 119944276

Following gene: 119944279

Centisome position: 13.98

GC content: 39.99

Gene sequence:

>2283_bases
ATGTTAAGTCAATTGCGGAATATAGTAGAGCAGGTCGGCAATGCAAAAAATTTAACTGAGGCCATGGACATTCTGGTGCG
CCAAACCAAATTAGCCATGGAAGTCGACTGCTGCTCTATTTATATTACCGATCAAAGTACTTCTCAACTTAATTTAATAG
CCAGTGAAGGCCTTGCAAGCCAAGTTGTTGGTTTTTCCTATCTCAAATTTGGCGAAGGTATTATAGGCTTAATTCACCAG
AAGGGAGAGCCTTTAAACATTGCCAACATCACCGAACACCCCAATTACAAATATCTGCCGAGCAGTGGAGAGGAGTCTTT
TAATTCATTATTAGGCACCCCGATTATCCATCGTCGAAAAGCATTAGGGGTGTTGGTTGTACAGCAAAAAGAACCCCGTT
TATTCAGCGAATTAGAAGAATCTTTTTTACTTACCCTCGCAATGCATTTAGCCAGTGTACTTGACCAGCCGTTTAGTTTA
GATGTTGAACGATTAAACCAGCCAAGGGCATCAATTTATCTGCAGGGCTCTCCTGCAAGTCCGGGCATTGCAATTGCAGA
TGCGTATGTTGTACGTTCTATTATGACATTAGCGGAAGTTATCATAGGAAAAAGTCACTCGGTCGTTAAAGAGCTCCTGC
TGTTTGAGATAATAGTCAAAAAATGCATCGACGAATTTTCTAATCTGGCATTAACACTTAAAGAACAAGTGTCAAAAGAT
GCCTTCATTCTGTTTGATATTTACTCGCATATTCTAAAGGATAAAACATTTTTAAATGCCATTAGATCACAAATCAATGA
ATCTCATTTAAATGCCCCCAGTGCAGTTAAAGTTGTCGCAGAGTCTTATATCAAACAATTTGAGGCAATGAGTGATCCCT
ATTTAAGTCAACGCTCTTCAGATATTCGCGATGTTGCCCAACGTTTGTTATACCATCTTACGCATCAGGTTGAAGATGAT
TTAAAGTTACCCGATAAGCTTATTCTAGTGGCTAATGAAGTGACTTTATCTATGGTTGCGAGTATCCCAAATGACAAGTT
ACAGGGCATTGTCTCGGTTCACGGTGGCATTGGTTCTCACGTGGCGATTTTAGCGCGAACACTCGGTATTCCGGCGGTAA
TGGGGGTGCAATTTTCCTTAGATAATATTAATCAAAAAAGTTTAATTATCGATGGTTATGAAGGTGGCGTGATTCTGCTG
CCTGAGCAATCATTAGTGAGTCATTATCAATCTGTGCTAGATGAAGAAAATGAATTAAAAAAGCTGGTTGAATCTGATCC
GCATGAAAAAGCCGTTACCCTTGATGGTCATGCTATTTCGATACTGCTCAACACAGGTTTAAATGCCAAGCAGCACGGGA
CAATATTAGGGCATTTTGATGGCATAGGTTTATACCGCAGTGAATTACCTTTTATATTGACGGACTCTTTTCCTACCGAA
CAGGAACAGGTGCAAGTCTACCAACGACTACTTGATCAATATCCCAAGTTACCGGTGACCATGCGCACCTTGGATATTGG
TGGTGATAAATCCCTGAGTTATTTTCCGATAGTTGAAGATAACCCTTTTCTTGGCTGGCGTGGAATTCGTTTAACCTTGG
ATCATCCTGAAATATTTTTGGTTCAGATTAGAGCGATGTTAAGAGCCAGTGTAAAGCATCAAAATTTACGTATTATGCTG
CCAATGGTCACTTCAATTGAAGAAGTGGACGAAGCCCATAAATTGATTACCCAAGCATGGAATGAAATTAAGTTTGAGCT
TAATTATTCCTCCGAAGCATTCCCTATGCCTGCGATAGGTGCAATGGTTGAGGTACCTGCTGCTGTTTTCCTTATTCCTG
CACTTGCCAAAAAAGTAGACTTTGTTTCAGTTGGCAGCAATGACCTTATCCAATATTTATTAGCGGTGGATAGAAATAAT
AGTCGTGTGGCGTCGCTTTACGATAGTTATCATCCTGCCGTGCTGCAAGCGCTAAAAATGATTATAGATAACAGTAAGCG
TTTTGATTTGGAAGTGAGTATCTGCGGCGAGCTTGCCAGTGATCCTATTGGTGCTTTAATTTTGATCGGTCTGGGCTATA
CCAAATTGAGCATGAACTCCTATAATATGGGCCGAATCAAGTATTTAATTAATGCGCTTCCCCGTTATGAATTAGAGTCT
TGTGTAGAGCAGGCTTTAAAGGCAAACAAGGGTACAGATATTCGCGCTATTTTTGTTGATTACCTTAATATAAAAGAATT
AGGCGGGTTTATTCGTGCAGGTAATAGCAAAAAAAATAATTAA

Upstream 100 bases:

>100_bases
TAATGAAAAAAAGTTCAGACAAGAAAAGGAATAAACGGCCTCGTCGGGCATCTTTTTATAAAAAAAGATAACAGAGCTTT
TTCTAAGAAAGGCGTTTTGT

Downstream 100 bases:

>100_bases
GCGATTACATTATAAAATAGGCACAACCCCTTTAACTGTTAGTTTAAAGGAGTATTTTTACCTTTTAATTTAGATCACCC
TTTTTTTAGTCTAAATAATC

Product: phosphoenolpyruvate-protein phosphotransferase PtsP

Products: NA

Alternate protein names: Enzyme I-Ntr; Phosphotransferase system, enzyme I [H]

Number of amino acids: Translated: 760; Mature: 760

Protein sequence:

>760_residues
MLSQLRNIVEQVGNAKNLTEAMDILVRQTKLAMEVDCCSIYITDQSTSQLNLIASEGLASQVVGFSYLKFGEGIIGLIHQ
KGEPLNIANITEHPNYKYLPSSGEESFNSLLGTPIIHRRKALGVLVVQQKEPRLFSELEESFLLTLAMHLASVLDQPFSL
DVERLNQPRASIYLQGSPASPGIAIADAYVVRSIMTLAEVIIGKSHSVVKELLLFEIIVKKCIDEFSNLALTLKEQVSKD
AFILFDIYSHILKDKTFLNAIRSQINESHLNAPSAVKVVAESYIKQFEAMSDPYLSQRSSDIRDVAQRLLYHLTHQVEDD
LKLPDKLILVANEVTLSMVASIPNDKLQGIVSVHGGIGSHVAILARTLGIPAVMGVQFSLDNINQKSLIIDGYEGGVILL
PEQSLVSHYQSVLDEENELKKLVESDPHEKAVTLDGHAISILLNTGLNAKQHGTILGHFDGIGLYRSELPFILTDSFPTE
QEQVQVYQRLLDQYPKLPVTMRTLDIGGDKSLSYFPIVEDNPFLGWRGIRLTLDHPEIFLVQIRAMLRASVKHQNLRIML
PMVTSIEEVDEAHKLITQAWNEIKFELNYSSEAFPMPAIGAMVEVPAAVFLIPALAKKVDFVSVGSNDLIQYLLAVDRNN
SRVASLYDSYHPAVLQALKMIIDNSKRFDLEVSICGELASDPIGALILIGLGYTKLSMNSYNMGRIKYLINALPRYELES
CVEQALKANKGTDIRAIFVDYLNIKELGGFIRAGNSKKNN

Sequences:

>Translated_760_residues
MLSQLRNIVEQVGNAKNLTEAMDILVRQTKLAMEVDCCSIYITDQSTSQLNLIASEGLASQVVGFSYLKFGEGIIGLIHQ
KGEPLNIANITEHPNYKYLPSSGEESFNSLLGTPIIHRRKALGVLVVQQKEPRLFSELEESFLLTLAMHLASVLDQPFSL
DVERLNQPRASIYLQGSPASPGIAIADAYVVRSIMTLAEVIIGKSHSVVKELLLFEIIVKKCIDEFSNLALTLKEQVSKD
AFILFDIYSHILKDKTFLNAIRSQINESHLNAPSAVKVVAESYIKQFEAMSDPYLSQRSSDIRDVAQRLLYHLTHQVEDD
LKLPDKLILVANEVTLSMVASIPNDKLQGIVSVHGGIGSHVAILARTLGIPAVMGVQFSLDNINQKSLIIDGYEGGVILL
PEQSLVSHYQSVLDEENELKKLVESDPHEKAVTLDGHAISILLNTGLNAKQHGTILGHFDGIGLYRSELPFILTDSFPTE
QEQVQVYQRLLDQYPKLPVTMRTLDIGGDKSLSYFPIVEDNPFLGWRGIRLTLDHPEIFLVQIRAMLRASVKHQNLRIML
PMVTSIEEVDEAHKLITQAWNEIKFELNYSSEAFPMPAIGAMVEVPAAVFLIPALAKKVDFVSVGSNDLIQYLLAVDRNN
SRVASLYDSYHPAVLQALKMIIDNSKRFDLEVSICGELASDPIGALILIGLGYTKLSMNSYNMGRIKYLINALPRYELES
CVEQALKANKGTDIRAIFVDYLNIKELGGFIRAGNSKKNN
>Mature_760_residues
MLSQLRNIVEQVGNAKNLTEAMDILVRQTKLAMEVDCCSIYITDQSTSQLNLIASEGLASQVVGFSYLKFGEGIIGLIHQ
KGEPLNIANITEHPNYKYLPSSGEESFNSLLGTPIIHRRKALGVLVVQQKEPRLFSELEESFLLTLAMHLASVLDQPFSL
DVERLNQPRASIYLQGSPASPGIAIADAYVVRSIMTLAEVIIGKSHSVVKELLLFEIIVKKCIDEFSNLALTLKEQVSKD
AFILFDIYSHILKDKTFLNAIRSQINESHLNAPSAVKVVAESYIKQFEAMSDPYLSQRSSDIRDVAQRLLYHLTHQVEDD
LKLPDKLILVANEVTLSMVASIPNDKLQGIVSVHGGIGSHVAILARTLGIPAVMGVQFSLDNINQKSLIIDGYEGGVILL
PEQSLVSHYQSVLDEENELKKLVESDPHEKAVTLDGHAISILLNTGLNAKQHGTILGHFDGIGLYRSELPFILTDSFPTE
QEQVQVYQRLLDQYPKLPVTMRTLDIGGDKSLSYFPIVEDNPFLGWRGIRLTLDHPEIFLVQIRAMLRASVKHQNLRIML
PMVTSIEEVDEAHKLITQAWNEIKFELNYSSEAFPMPAIGAMVEVPAAVFLIPALAKKVDFVSVGSNDLIQYLLAVDRNN
SRVASLYDSYHPAVLQALKMIIDNSKRFDLEVSICGELASDPIGALILIGLGYTKLSMNSYNMGRIKYLINALPRYELES
CVEQALKANKGTDIRAIFVDYLNIKELGGFIRAGNSKKNN

Specific function: Component of the phosphoenolpyruvate-dependent nitrogen- metabolic phosphotransferase system (nitrogen-metabolic PTS), that seems to be involved in regulating nitrogen metabolism. Enzyme I- Ntr transfers the phosphoryl group from phosphoenolpyruvate (PEP)

COG id: COG3605

COG function: function code T; Signal transduction protein containing GAF and PtsI domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GAF domain [H]

Homologues:

Organism=Escherichia coli, GI1789193, Length=754, Percent_Identity=43.1034482758621, Blast_Score=642, Evalue=0.0,
Organism=Escherichia coli, GI1788756, Length=572, Percent_Identity=35.1398601398601, Blast_Score=298, Evalue=8e-82,
Organism=Escherichia coli, GI48994992, Length=478, Percent_Identity=31.3807531380753, Blast_Score=242, Evalue=8e-65,
Organism=Escherichia coli, GI1788726, Length=529, Percent_Identity=32.3251417769376, Blast_Score=236, Evalue=4e-63,
Organism=Escherichia coli, GI1787994, Length=407, Percent_Identity=26.2899262899263, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003018
- InterPro:   IPR008279
- InterPro:   IPR006318
- InterPro:   IPR018274
- InterPro:   IPR023151
- InterPro:   IPR000121
- InterPro:   IPR008731
- InterPro:   IPR015813 [H]

Pfam domain/function: PF01590 GAF; PF05524 PEP-utilisers_N; PF00391 PEP-utilizers; PF02896 PEP-utilizers_C [H]

EC number: =2.7.3.9 [H]

Molecular weight: Translated: 84403; Mature: 84403

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS00742 PEP_ENZYMES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSQLRNIVEQVGNAKNLTEAMDILVRQTKLAMEVDCCSIYITDQSTSQLNLIASEGLAS
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEEEEEEEEECCCCCCEEEEHHCCHHH
QVVGFSYLKFGEGIIGLIHQKGEPLNIANITEHPNYKYLPSSGEESFNSLLGTPIIHRRK
HHHHHHHHHHCCCHHHHEECCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHCCCHHHHHH
ALGVLVVQQKEPRLFSELEESFLLTLAMHLASVLDQPFSLDVERLNQPRASIYLQGSPAS
HCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCEEEEEECCCCC
PGIAIADAYVVRSIMTLAEVIIGKSHSVVKELLLFEIIVKKCIDEFSNLALTLKEQVSKD
CCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHCCCC
AFILFDIYSHILKDKTFLNAIRSQINESHLNAPSAVKVVAESYIKQFEAMSDPYLSQRSS
CEEHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCC
DIRDVAQRLLYHLTHQVEDDLKLPDKLILVANEVTLSMVASIPNDKLQGIVSVHGGIGSH
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHCCCHHHCEEEEECCCCCHH
VAILARTLGIPAVMGVQFSLDNINQKSLIIDGYEGGVILLPEQSLVSHYQSVLDEENELK
HHHHHHHHCCCEEEEEEEECCCCCCCEEEEECCCCCEEEECCHHHHHHHHHHHCCHHHHH
KLVESDPHEKAVTLDGHAISILLNTGLNAKQHGTILGHFDGIGLYRSELPFILTDSFPTE
HHHHCCCCCCEEEECCCEEEEEEECCCCCCCCCCEEEECCCCCCHHHCCCEEEECCCCCH
QEQVQVYQRLLDQYPKLPVTMRTLDIGGDKSLSYFPIVEDNPFLGWRGIRLTLDHPEIFL
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCEEEEEEEECCCHHHH
VQIRAMLRASVKHQNLRIMLPMVTSIEEVDEAHKLITQAWNEIKFELNYSSEAFPMPAIG
HHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHH
AMVEVPAAVFLIPALAKKVDFVSVGSNDLIQYLLAVDRNNSRVASLYDSYHPAVLQALKM
HHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHH
IIDNSKRFDLEVSICGELASDPIGALILIGLGYTKLSMNSYNMGRIKYLINALPRYELES
HHCCCCCEEEEEEEHHHHHCCCCCEEEEEECCCEEEECCCCCCHHHHHHHHHCCCHHHHH
CVEQALKANKGTDIRAIFVDYLNIKELGGFIRAGNSKKNN
HHHHHHHCCCCCCEEEEEEHHHHHHHHCHHHCCCCCCCCC
>Mature Secondary Structure
MLSQLRNIVEQVGNAKNLTEAMDILVRQTKLAMEVDCCSIYITDQSTSQLNLIASEGLAS
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEEEEEEEEECCCCCCEEEEHHCCHHH
QVVGFSYLKFGEGIIGLIHQKGEPLNIANITEHPNYKYLPSSGEESFNSLLGTPIIHRRK
HHHHHHHHHHCCCHHHHEECCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHCCCHHHHHH
ALGVLVVQQKEPRLFSELEESFLLTLAMHLASVLDQPFSLDVERLNQPRASIYLQGSPAS
HCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCEEEEEECCCCC
PGIAIADAYVVRSIMTLAEVIIGKSHSVVKELLLFEIIVKKCIDEFSNLALTLKEQVSKD
CCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHCCCC
AFILFDIYSHILKDKTFLNAIRSQINESHLNAPSAVKVVAESYIKQFEAMSDPYLSQRSS
CEEHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCC
DIRDVAQRLLYHLTHQVEDDLKLPDKLILVANEVTLSMVASIPNDKLQGIVSVHGGIGSH
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHCCCHHHCEEEEECCCCCHH
VAILARTLGIPAVMGVQFSLDNINQKSLIIDGYEGGVILLPEQSLVSHYQSVLDEENELK
HHHHHHHHCCCEEEEEEEECCCCCCCEEEEECCCCCEEEECCHHHHHHHHHHHCCHHHHH
KLVESDPHEKAVTLDGHAISILLNTGLNAKQHGTILGHFDGIGLYRSELPFILTDSFPTE
HHHHCCCCCCEEEECCCEEEEEEECCCCCCCCCCEEEECCCCCCHHHCCCEEEECCCCCH
QEQVQVYQRLLDQYPKLPVTMRTLDIGGDKSLSYFPIVEDNPFLGWRGIRLTLDHPEIFL
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCEEEEEEEECCCHHHH
VQIRAMLRASVKHQNLRIMLPMVTSIEEVDEAHKLITQAWNEIKFELNYSSEAFPMPAIG
HHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHH
AMVEVPAAVFLIPALAKKVDFVSVGSNDLIQYLLAVDRNNSRVASLYDSYHPAVLQALKM
HHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHH
IIDNSKRFDLEVSICGELASDPIGALILIGLGYTKLSMNSYNMGRIKYLINALPRYELES
HHCCCCCEEEEEEEHHHHHCCCCCEEEEEECCCEEEECCCCCCHHHHHHHHHCCCHHHHH
CVEQALKANKGTDIRAIFVDYLNIKELGGFIRAGNSKKNN
HHHHHHHCCCCCCEEEEEEHHHHHHHHCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 7896715; 8973315 [H]