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The map label for this gene is pip [H]

Identifier: 119944039

GI number: 119944039

Start: 329821

End: 330783

Strand: Reverse

Name: pip [H]

Synonym: Ping_0253

Alternate gene names: 119944039

Gene position: 330783-329821 (Counterclockwise)

Preceding gene: 119944042

Following gene: 119944038

Centisome position: 7.25

GC content: 44.24

Gene sequence:

>963_bases
ATGAACGAATTATACCCTGAAATTGAGCCCTTTAATGATTTTCTCTTAGACGTTGGCTGCCAGCACCAGCTGTACGTAGA
ACAATGTGGTAACGTTAACGGCCAGCCAGTCATCTTTATTCACGGTGGGCCCGGTGCAGGTTCCTCCGCTAATGACCGAC
GTTTTTTCGACCCTGAAAAATATCATATTATTTTATTTGATCAACGAGGTTGTGGACGATCGACTCCTTATGGCAGCTTA
GCAGACAATACTACCGTGCAGTTAGTCGCTGATCTTGAGAAAATACGCAACCATCTTCAGCTTGATAAATGGCATGTATT
TGGAGGTTCATGGGGATCAACCCTCGCATTGGTCTATGCTCAGACTCATGCTGAACAGGTGCTCAGTTTGGTGCTCAGAG
GAATATTTTTAGGTCGGGTGCAAGATACTGAGTGGACTTTTGCTGGCGGTGGTGGCTCGCGTATTTTTGCTGATTATTGG
CAAGAATATTTAGCTACCCTGCCCGCAGCTATACTTAGTCAACATAATCATGTCAAAGTCGCTTACGACATTATGACTGG
CAACGACAAAGATGCCGCTGAAAAAGTAGCACAAGCCTGGGCTAACTGGGAAATGCGTTGTTGTACCCTAGAGCCCAATG
ATGAATTTGTCAGCGCCGCAACTTCTGATGATAGTTGCTGGACGCTAGCACGCCATGAAGCCCATTACATGGTCAATAAG
TGCTTCTTAACGGATAATCAAATTTTGAAAAATTGTGATAAAATAGCCAATATTCCTACTGTACTTGTTCATGGCCGTTA
TGACATTGTTTGCCCCTTTGATAACGCGTGGCTTTTGCATCAACAACTGCCTAACTCGCAATTAGTGATCAGTAAAACCG
CAGGTCATGCCTCGGTTGAACCTGAAACTAAGCATCACTTACTCAATGCCACCAACGCGATGTTGGAATTATCACATTAC
TAA

Upstream 100 bases:

>100_bases
TTAAGATTAATCAGTCGCGTATGAATGGCTCTGCATTGAGCTTTGTCCACTAAAAATAGCGACCATCACCCACCAGCAAT
GAACGGAGTAGCACCTTATA

Downstream 100 bases:

>100_bases
GACGCTATCTGCTATACTCAAACCCTATTGTATGGTGGTAATTCGCGTAAAGTCCCCGATAAAAATGCTCGGGGATAACT
TCAAAGATTAAGCAATAAAA

Product: proline iminopeptidase

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MNELYPEIEPFNDFLLDVGCQHQLYVEQCGNVNGQPVIFIHGGPGAGSSANDRRFFDPEKYHIILFDQRGCGRSTPYGSL
ADNTTVQLVADLEKIRNHLQLDKWHVFGGSWGSTLALVYAQTHAEQVLSLVLRGIFLGRVQDTEWTFAGGGGSRIFADYW
QEYLATLPAAILSQHNHVKVAYDIMTGNDKDAAEKVAQAWANWEMRCCTLEPNDEFVSAATSDDSCWTLARHEAHYMVNK
CFLTDNQILKNCDKIANIPTVLVHGRYDIVCPFDNAWLLHQQLPNSQLVISKTAGHASVEPETKHHLLNATNAMLELSHY

Sequences:

>Translated_320_residues
MNELYPEIEPFNDFLLDVGCQHQLYVEQCGNVNGQPVIFIHGGPGAGSSANDRRFFDPEKYHIILFDQRGCGRSTPYGSL
ADNTTVQLVADLEKIRNHLQLDKWHVFGGSWGSTLALVYAQTHAEQVLSLVLRGIFLGRVQDTEWTFAGGGGSRIFADYW
QEYLATLPAAILSQHNHVKVAYDIMTGNDKDAAEKVAQAWANWEMRCCTLEPNDEFVSAATSDDSCWTLARHEAHYMVNK
CFLTDNQILKNCDKIANIPTVLVHGRYDIVCPFDNAWLLHQQLPNSQLVISKTAGHASVEPETKHHLLNATNAMLELSHY
>Mature_320_residues
MNELYPEIEPFNDFLLDVGCQHQLYVEQCGNVNGQPVIFIHGGPGAGSSANDRRFFDPEKYHIILFDQRGCGRSTPYGSL
ADNTTVQLVADLEKIRNHLQLDKWHVFGGSWGSTLALVYAQTHAEQVLSLVLRGIFLGRVQDTEWTFAGGGGSRIFADYW
QEYLATLPAAILSQHNHVKVAYDIMTGNDKDAAEKVAQAWANWEMRCCTLEPNDEFVSAATSDDSCWTLARHEAHYMVNK
CFLTDNQILKNCDKIANIPTVLVHGRYDIVCPFDNAWLLHQQLPNSQLVISKTAGHASVEPETKHHLLNATNAMLELSHY

Specific function: Specifically catalyzes the removal of N-terminal proline residues from peptides [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005944
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 35889; Mature: 35889

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNELYPEIEPFNDFLLDVGCQHQLYVEQCGNVNGQPVIFIHGGPGAGSSANDRRFFDPEK
CCCCCCCCCCCHHHHHHCCCCCEEHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
YHIILFDQRGCGRSTPYGSLADNTTVQLVADLEKIRNHLQLDKWHVFGGSWGSTLALVYA
EEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEE
QTHAEQVLSLVLRGIFLGRVQDTEWTFAGGGGSRIFADYWQEYLATLPAAILSQHNHVKV
HHHHHHHHHHHHHHHHHCCEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEE
AYDIMTGNDKDAAEKVAQAWANWEMRCCTLEPNDEFVSAATSDDSCWTLARHEAHYMVNK
EEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCHHEEECCCCCCEEEHHHHHHHHEEEE
CFLTDNQILKNCDKIANIPTVLVHGRYDIVCPFDNAWLLHQQLPNSQLVISKTAGHASVE
EEECCCHHHHHHHHHCCCCEEEEECCEEEEECCCCCEEEEHHCCCCEEEEEECCCCCCCC
PETKHHLLNATNAMLELSHY
CCHHHHHHHHHHHEEEECCC
>Mature Secondary Structure
MNELYPEIEPFNDFLLDVGCQHQLYVEQCGNVNGQPVIFIHGGPGAGSSANDRRFFDPEK
CCCCCCCCCCCHHHHHHCCCCCEEHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
YHIILFDQRGCGRSTPYGSLADNTTVQLVADLEKIRNHLQLDKWHVFGGSWGSTLALVYA
EEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEE
QTHAEQVLSLVLRGIFLGRVQDTEWTFAGGGGSRIFADYWQEYLATLPAAILSQHNHVKV
HHHHHHHHHHHHHHHHHCCEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEE
AYDIMTGNDKDAAEKVAQAWANWEMRCCTLEPNDEFVSAATSDDSCWTLARHEAHYMVNK
EEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCHHEEECCCCCCEEEHHHHHHHHEEEE
CFLTDNQILKNCDKIANIPTVLVHGRYDIVCPFDNAWLLHQQLPNSQLVISKTAGHASVE
EEECCCHHHHHHHHHCCCCEEEEECCEEEEECCCCCEEEEHHCCCCEEEEEECCCCCCCC
PETKHHLLNATNAMLELSHY
CCHHHHHHHHHHHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]