Click here to switch to the map view.

The map label for this gene is intA [H]

Identifier: 119944020

GI number: 119944020

Start: 302809

End: 304059

Strand: Direct

Name: intA [H]

Synonym: Ping_0234

Alternate gene names: 119944020

Gene position: 302809-304059 (Clockwise)

Preceding gene: 119944018

Following gene: 119944027

Centisome position: 6.64

GC content: 40.85

Gene sequence:

>1251_bases
ATGGCTAAAACCACACCACTTTCAGACACCCAGATTAGATTAACCAAAGCTAGCGATAAGGTAATTACTTTATCTGACGG
TGGCGGCTTACAGCTGAGAATCAAACCAAATGGTTCTAAGCTGTGGCAGTTACGTTTTAATAAGCCGATTGAGAAAAAAC
CTGCATTGATGGGTTTTGGTGCTTATCCCGCTATTTCGTTAGCTAATGCTAGAAAGTTACGCGAGGCTGCCAATGAGTTA
TTAGCACAAGGTATTAATCCCAAAGCTCAGCGTGATAGTGAAATTAAAGAAAAAGAACTAATTCTAAACAATACATTTGA
AATGGTTACGGCTGCTTGGATAAAGCTTAAAGCGTCAGAAGTAAAGCCGGATTCATTAAAAACTATTTCTACCACGCTTA
CTAATCATATCCTGCCTCGTATTGGTAAATGCCCAATAACAGAAATTACAGCGCCTATGGCCATTGAAGCGCTTAGACCG
ATAGAAGCCAAAGGTAACCACGAAGTTATTGCGAGAGCTTGTCAATACCTCAACCAGATCATGCGCTATGCAACTAATCT
TGGCATGATCCATTCCAACCCTTTAACTGGTATTAAAGGGGTATTTATGACTAAAAAGATCACGAACAACCCACATGTAA
AGCCTGAAGAACTTCCACAGTTACTAATGGCTATTGCTACTGCCAATATTAAGAAAATAACACGCAACCTAATTCTGTGG
CAGTTGCATACAATGACTAGACCCGCTGAAACTGCACTAGCACAGTGGAATGAAATAGATTACGAAAATAATTTGTGGAT
TATTCCTGGTGAGCGGATTAAAACAGGTATGACTCATCAGATCCCACTCACTGTACAGACATTGGCGATACTTGAAGCTT
GCAAGGTGATTAGTGGTAATTCGGACTATATTTTCCCTGCAGATAGAAACCCTAATGCTCATGCAAATAAAGCCAGTGCA
AACATGGCATTTAAACGTATGGGCTATCAAGGTAGACAGACAGCACACGGTTTGCGTGGTTTAGCGAGGACAACACTTAG
TGATAAAGGCGTCGCATACGAGCCTTCCGAGGCTTGTTTGTCACATAAAGTAGGTAATTCAGTTAGCCAGTCCTACAATC
ACTCCACGTACCTTAATCAACGAATAAAAATAATGGCGTGGTGGAGTAATTACATTGAAGAAGCTTCTTATGGAAATATT
TCAATGGCAGGCAGCAAAGGCGTGAAGGTTGTTGGGACTGATCAAACATGA

Upstream 100 bases:

>100_bases
TTAGTGTCCCGTAGCGTCTCTAATAGTACCGTGACATCTACTGTTTAAAGTAATACCATAACTAATACCACTCAAACCCA
AAAAATGCTGGTATTACTTC

Downstream 100 bases:

>100_bases
TGTACATATATTAATATTAAAAAATACCTGTAAATCTCGTTTTTATTTCTCATTCAGTGGCATGAAACCTGAGTCGCTAA
GGGGCACATTGCGCCTTAGA

Product: phage integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MAKTTPLSDTQIRLTKASDKVITLSDGGGLQLRIKPNGSKLWQLRFNKPIEKKPALMGFGAYPAISLANARKLREAANEL
LAQGINPKAQRDSEIKEKELILNNTFEMVTAAWIKLKASEVKPDSLKTISTTLTNHILPRIGKCPITEITAPMAIEALRP
IEAKGNHEVIARACQYLNQIMRYATNLGMIHSNPLTGIKGVFMTKKITNNPHVKPEELPQLLMAIATANIKKITRNLILW
QLHTMTRPAETALAQWNEIDYENNLWIIPGERIKTGMTHQIPLTVQTLAILEACKVISGNSDYIFPADRNPNAHANKASA
NMAFKRMGYQGRQTAHGLRGLARTTLSDKGVAYEPSEACLSHKVGNSVSQSYNHSTYLNQRIKIMAWWSNYIEEASYGNI
SMAGSKGVKVVGTDQT

Sequences:

>Translated_416_residues
MAKTTPLSDTQIRLTKASDKVITLSDGGGLQLRIKPNGSKLWQLRFNKPIEKKPALMGFGAYPAISLANARKLREAANEL
LAQGINPKAQRDSEIKEKELILNNTFEMVTAAWIKLKASEVKPDSLKTISTTLTNHILPRIGKCPITEITAPMAIEALRP
IEAKGNHEVIARACQYLNQIMRYATNLGMIHSNPLTGIKGVFMTKKITNNPHVKPEELPQLLMAIATANIKKITRNLILW
QLHTMTRPAETALAQWNEIDYENNLWIIPGERIKTGMTHQIPLTVQTLAILEACKVISGNSDYIFPADRNPNAHANKASA
NMAFKRMGYQGRQTAHGLRGLARTTLSDKGVAYEPSEACLSHKVGNSVSQSYNHSTYLNQRIKIMAWWSNYIEEASYGNI
SMAGSKGVKVVGTDQT
>Mature_415_residues
AKTTPLSDTQIRLTKASDKVITLSDGGGLQLRIKPNGSKLWQLRFNKPIEKKPALMGFGAYPAISLANARKLREAANELL
AQGINPKAQRDSEIKEKELILNNTFEMVTAAWIKLKASEVKPDSLKTISTTLTNHILPRIGKCPITEITAPMAIEALRPI
EAKGNHEVIARACQYLNQIMRYATNLGMIHSNPLTGIKGVFMTKKITNNPHVKPEELPQLLMAIATANIKKITRNLILWQ
LHTMTRPAETALAQWNEIDYENNLWIIPGERIKTGMTHQIPLTVQTLAILEACKVISGNSDYIFPADRNPNAHANKASAN
MAFKRMGYQGRQTAHGLRGLARTTLSDKGVAYEPSEACLSHKVGNSVSQSYNHSTYLNQRIKIMAWWSNYIEEASYGNIS
MAGSKGVKVVGTDQT

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=410, Percent_Identity=40.4878048780488, Blast_Score=333, Evalue=1e-92,
Organism=Escherichia coli, GI1788690, Length=392, Percent_Identity=26.530612244898, Blast_Score=154, Evalue=8e-39,
Organism=Escherichia coli, GI145693166, Length=402, Percent_Identity=28.3582089552239, Blast_Score=146, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 46077; Mature: 45946

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTTPLSDTQIRLTKASDKVITLSDGGGLQLRIKPNGSKLWQLRFNKPIEKKPALMGFG
CCCCCCCCCCEEEEEECCCCEEEEECCCCEEEEEECCCCEEEEEECCCCCCCCCCEEECC
AYPAISLANARKLREAANELLAQGINPKAQRDSEIKEKELILNNTFEMVTAAWIKLKASE
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHEEECCC
VKPDSLKTISTTLTNHILPRIGKCPITEITAPMAIEALRPIEAKGNHEVIARACQYLNQI
CCCCHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
MRYATNLGMIHSNPLTGIKGVFMTKKITNNPHVKPEELPQLLMAIATANIKKITRNLILW
HHHHHHCCCEECCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHE
QLHTMTRPAETALAQWNEIDYENNLWIIPGERIKTGMTHQIPLTVQTLAILEACKVISGN
EHHHCCCCHHHHHHHHHCCCCCCCEEEECCHHHCCCCCEECCHHHHHHHHHHHHHHHCCC
SDYIFPADRNPNAHANKASANMAFKRMGYQGRQTAHGLRGLARTTLSDKGVAYEPSEACL
CCEEEECCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHH
SHKVGNSVSQSYNHSTYLNQRIKIMAWWSNYIEEASYGNISMAGSKGVKVVGTDQT
HHHHCCHHHHHCCCHHHHCCCEEEEEEHHHHHHHCCCCCEEECCCCCEEEEECCCC
>Mature Secondary Structure 
AKTTPLSDTQIRLTKASDKVITLSDGGGLQLRIKPNGSKLWQLRFNKPIEKKPALMGFG
CCCCCCCCCEEEEEECCCCEEEEECCCCEEEEEECCCCEEEEEECCCCCCCCCCEEECC
AYPAISLANARKLREAANELLAQGINPKAQRDSEIKEKELILNNTFEMVTAAWIKLKASE
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHEEECCC
VKPDSLKTISTTLTNHILPRIGKCPITEITAPMAIEALRPIEAKGNHEVIARACQYLNQI
CCCCHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
MRYATNLGMIHSNPLTGIKGVFMTKKITNNPHVKPEELPQLLMAIATANIKKITRNLILW
HHHHHHCCCEECCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHE
QLHTMTRPAETALAQWNEIDYENNLWIIPGERIKTGMTHQIPLTVQTLAILEACKVISGN
EHHHCCCCHHHHHHHHHCCCCCCCEEEECCHHHCCCCCEECCHHHHHHHHHHHHHHHCCC
SDYIFPADRNPNAHANKASANMAFKRMGYQGRQTAHGLRGLARTTLSDKGVAYEPSEACL
CCEEEECCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHH
SHKVGNSVSQSYNHSTYLNQRIKIMAWWSNYIEEASYGNISMAGSKGVKVVGTDQT
HHHHCCHHHHHCCCHHHHCCCEEEEEEHHHHHHHCCCCCEEECCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7511583; 9278503; 9205837; 7524073 [H]