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The map label for this gene is aroB

Identifier: 119943951

GI number: 119943951

Start: 214434

End: 215504

Strand: Direct

Name: aroB

Synonym: Ping_0164

Alternate gene names: 119943951

Gene position: 214434-215504 (Clockwise)

Preceding gene: 119943950

Following gene: 119943952

Centisome position: 4.7

GC content: 38.66

Gene sequence:

>1071_bases
ATGGAAAAAATAGTTGTAGCGCTGGGTAAGCGTAGTTATCCGATATCAATTGGTGAAGGTTTATTAACTCATGCTGAGTT
ATTCAAATCGGCAATCAAGGGCAAAAGGGTCATGATTGTCAGCAATGAAATCGTTGCGCCTTTGTATTTAGCTTGTTGTA
AAGAGACTTTAATTGATTTTCAAATTGATGAAATTATTTTACCCGATGGTGAAAAGTTCAAAAATTTACATACTTTTGAA
ATCATTTTAACTGCTTTGCTGTCTAATAAACACGCACGTGATACGACTATTATTGCGCTGGGTGGTGGGGTTATCGGTGA
TATGGCTGGTTTTGCTGCCGCTTGTTATCAGCGAGGAGTACCCTTTATCCAAGTGCCAACAACCGTTTTATCACAAGTTG
ATTCTTCCGTTGGTGGAAAAACCGCGGTTAATCATCCTCTGGGTAAGAATATGATTGGCGCGTTTTATCAACCTCAGTCA
GTTATTATTGATATAGATTGCCTTAAAACATTACCTGCACGTGAATTTTCAGCGGGAATGGCCGAAGTCATTAAATACGG
CATTCTTTATGATCAGGCATTTTTTATCTGGCTTGAAGAAAATGTTACCGCGATTAAAACCTTACAACCCGCTGCTATTA
CCTATATGATTAAACGTTGCTGCGAAATTAAAGCTGAAATTGTCTCTCTGGATGAAAAAGAGGGTGGTATTCGCGCATTG
TTGAATCTTGGACATACCTTTGGTCATGCGATAGAGGCTGAGCAAGGTTATGGTAATTGGCTGCATGGTGAAGCTGTTGC
CTCAGGTATGGTACTGGCTGCAAAAACTGCTTTAAACCTTGGCCTCATTGAATCTGCACAAATTGAGCAAATTATATTAT
TAATTAAACAGTTTGATCTGCCCGTTAATGCACCAGAAAATATGCATTACGATCAGTTTTTCGATCATATGCAACTCGAC
AAAAAAGTATTAGATGGCAAGTTACGTTTGATTTTACCAACCTCGATCGGTCGCTGTGAAATATTTGATAATGTGAGTGA
AACAGTTCTTCGCAGTGTTATAGAGTCTTAA

Upstream 100 bases:

>100_bases
GTAATGAGTTTTATGATGAAGTAGCTGATTATACGATGGAAACAGATGAGCAAAGCGCGAAGGTTGTCGCTAGTCAAATC
ATTGCATTATTGGATTTCTA

Downstream 100 bases:

>100_bases
ATTGACGATGCTGAGTCTAATATAATCAGTTGGGTGAAAAGAATAAAAATCATATTTTATGAAATGTAGCAGCGAATAGG
CTGATCTCTTTTTTTAGTAG

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MEKIVVALGKRSYPISIGEGLLTHAELFKSAIKGKRVMIVSNEIVAPLYLACCKETLIDFQIDEIILPDGEKFKNLHTFE
IILTALLSNKHARDTTIIALGGGVIGDMAGFAAACYQRGVPFIQVPTTVLSQVDSSVGGKTAVNHPLGKNMIGAFYQPQS
VIIDIDCLKTLPAREFSAGMAEVIKYGILYDQAFFIWLEENVTAIKTLQPAAITYMIKRCCEIKAEIVSLDEKEGGIRAL
LNLGHTFGHAIEAEQGYGNWLHGEAVASGMVLAAKTALNLGLIESAQIEQIILLIKQFDLPVNAPENMHYDQFFDHMQLD
KKVLDGKLRLILPTSIGRCEIFDNVSETVLRSVIES

Sequences:

>Translated_356_residues
MEKIVVALGKRSYPISIGEGLLTHAELFKSAIKGKRVMIVSNEIVAPLYLACCKETLIDFQIDEIILPDGEKFKNLHTFE
IILTALLSNKHARDTTIIALGGGVIGDMAGFAAACYQRGVPFIQVPTTVLSQVDSSVGGKTAVNHPLGKNMIGAFYQPQS
VIIDIDCLKTLPAREFSAGMAEVIKYGILYDQAFFIWLEENVTAIKTLQPAAITYMIKRCCEIKAEIVSLDEKEGGIRAL
LNLGHTFGHAIEAEQGYGNWLHGEAVASGMVLAAKTALNLGLIESAQIEQIILLIKQFDLPVNAPENMHYDQFFDHMQLD
KKVLDGKLRLILPTSIGRCEIFDNVSETVLRSVIES
>Mature_356_residues
MEKIVVALGKRSYPISIGEGLLTHAELFKSAIKGKRVMIVSNEIVAPLYLACCKETLIDFQIDEIILPDGEKFKNLHTFE
IILTALLSNKHARDTTIIALGGGVIGDMAGFAAACYQRGVPFIQVPTTVLSQVDSSVGGKTAVNHPLGKNMIGAFYQPQS
VIIDIDCLKTLPAREFSAGMAEVIKYGILYDQAFFIWLEENVTAIKTLQPAAITYMIKRCCEIKAEIVSLDEKEGGIRAL
LNLGHTFGHAIEAEQGYGNWLHGEAVASGMVLAAKTALNLGLIESAQIEQIILLIKQFDLPVNAPENMHYDQFFDHMQLD
KKVLDGKLRLILPTSIGRCEIFDNVSETVLRSVIES

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=358, Percent_Identity=60.6145251396648, Blast_Score=436, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6320332, Length=314, Percent_Identity=37.5796178343949, Blast_Score=192, Evalue=8e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_PSYIN (A1SRB7)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_941631.1
- ProteinModelPortal:   A1SRB7
- SMR:   A1SRB7
- STRING:   A1SRB7
- GeneID:   4626294
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_0164
- eggNOG:   COG0337
- HOGENOM:   HBG632303
- OMA:   CEIKAEV
- PhylomeDB:   A1SRB7
- BioCyc:   PING357804:PING_0164-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 39048; Mature: 39048

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKIVVALGKRSYPISIGEGLLTHAELFKSAIKGKRVMIVSNEIVAPLYLACCKETLIDF
CCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCE
QIDEIILPDGEKFKNLHTFEIILTALLSNKHARDTTIIALGGGVIGDMAGFAAACYQRGV
EECEEECCCCHHHCCCHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCC
PFIQVPTTVLSQVDSSVGGKTAVNHPLGKNMIGAFYQPQSVIIDIDCLKTLPAREFSAGM
CEEEECHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCEEEEEEHHHHCCCCHHHHHHH
AEVIKYGILYDQAFFIWLEENVTAIKTLQPAAITYMIKRCCEIKAEIVSLDEKEGGIRAL
HHHHHHHHHEECEEEEEEECCCEEEHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LNLGHTFGHAIEAEQGYGNWLHGEAVASGMVLAAKTALNLGLIESAQIEQIILLIKQFDL
HHHHHHHHCCEECCCCCCCCCCHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
PVNAPENMHYDQFFDHMQLDKKVLDGKLRLILPTSIGRCEIFDNVSETVLRSVIES
CCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEKIVVALGKRSYPISIGEGLLTHAELFKSAIKGKRVMIVSNEIVAPLYLACCKETLIDF
CCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCE
QIDEIILPDGEKFKNLHTFEIILTALLSNKHARDTTIIALGGGVIGDMAGFAAACYQRGV
EECEEECCCCHHHCCCHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCC
PFIQVPTTVLSQVDSSVGGKTAVNHPLGKNMIGAFYQPQSVIIDIDCLKTLPAREFSAGM
CEEEECHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCEEEEEEHHHHCCCCHHHHHHH
AEVIKYGILYDQAFFIWLEENVTAIKTLQPAAITYMIKRCCEIKAEIVSLDEKEGGIRAL
HHHHHHHHHEECEEEEEEECCCEEEHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LNLGHTFGHAIEAEQGYGNWLHGEAVASGMVLAAKTALNLGLIESAQIEQIILLIKQFDL
HHHHHHHHCCEECCCCCCCCCCHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
PVNAPENMHYDQFFDHMQLDKKVLDGKLRLILPTSIGRCEIFDNVSETVLRSVIES
CCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA