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The map label for this gene is aroK

Identifier: 119943950

GI number: 119943950

Start: 213919

End: 214434

Strand: Direct

Name: aroK

Synonym: Ping_0163

Alternate gene names: 119943950

Gene position: 213919-214434 (Clockwise)

Preceding gene: 119943949

Following gene: 119943951

Centisome position: 4.69

GC content: 40.7

Gene sequence:

>516_bases
ATGGCAGAACAACGTAATATTTTCTTAATTGGCCCAATGGGCGCCGGCAAAAGCACAATTGGTCGTCATTTAGCACAAAT
GTTACACCTTGATTTTCTTGATTCTGATGCAGAGATTGAGAAAAAAACGGGTGCAGACATTGCGTGGGTTTTTGATGTAG
AGGGCGAAGAGGGTTTCCGTAATCGCGAACAAAGCATGATTGATGAGCTGACACAAAAGCATGGTATCGTTTTAGCAACA
GGTGGCGGAGCACTTATTCGCCCTGAAAATAGGATACATTTGTCGGCACGAGGTATTGTTGTTTACTTAAAAACCAGTGT
AAATAAACAGTTAGCCCGGACATTAAAAGATAAACGCCGTCCCTTATTACAAACAGATGATCCACGAACGGTATTAGAAG
CATTAGCTGAAAAACGTAATGAGTTTTATGATGAAGTAGCTGATTATACGATGGAAACAGATGAGCAAAGCGCGAAGGTT
GTCGCTAGTCAAATCATTGCATTATTGGATTTCTAA

Upstream 100 bases:

>100_bases
ATGGGCTTGCAATGGCTTATTAACAATTGCGATAATATACAACACTTCTCTTTTTCTAAAGGGTGTTCCCAGTAATTAAT
CACTTGAGTAATAATTCAAC

Downstream 100 bases:

>100_bases
TGGAAAAAATAGTTGTAGCGCTGGGTAAGCGTAGTTATCCGATATCAATTGGTGAAGGTTTATTAACTCATGCTGAGTTA
TTCAAATCGGCAATCAAGGG

Product: shikimate kinase

Products: NA

Alternate protein names: SK

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MAEQRNIFLIGPMGAGKSTIGRHLAQMLHLDFLDSDAEIEKKTGADIAWVFDVEGEEGFRNREQSMIDELTQKHGIVLAT
GGGALIRPENRIHLSARGIVVYLKTSVNKQLARTLKDKRRPLLQTDDPRTVLEALAEKRNEFYDEVADYTMETDEQSAKV
VASQIIALLDF

Sequences:

>Translated_171_residues
MAEQRNIFLIGPMGAGKSTIGRHLAQMLHLDFLDSDAEIEKKTGADIAWVFDVEGEEGFRNREQSMIDELTQKHGIVLAT
GGGALIRPENRIHLSARGIVVYLKTSVNKQLARTLKDKRRPLLQTDDPRTVLEALAEKRNEFYDEVADYTMETDEQSAKV
VASQIIALLDF
>Mature_170_residues
AEQRNIFLIGPMGAGKSTIGRHLAQMLHLDFLDSDAEIEKKTGADIAWVFDVEGEEGFRNREQSMIDELTQKHGIVLATG
GGALIRPENRIHLSARGIVVYLKTSVNKQLARTLKDKRRPLLQTDDPRTVLEALAEKRNEFYDEVADYTMETDEQSAKVV
ASQIIALLDF

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family

Homologues:

Organism=Escherichia coli, GI87082255, Length=171, Percent_Identity=67.2514619883041, Blast_Score=241, Evalue=2e-65,
Organism=Escherichia coli, GI1786587, Length=159, Percent_Identity=31.4465408805031, Blast_Score=84, Evalue=7e-18,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): AROK_PSYIN (A1SRB6)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_941630.1
- ProteinModelPortal:   A1SRB6
- SMR:   A1SRB6
- STRING:   A1SRB6
- GeneID:   4626293
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_0163
- eggNOG:   COG0703
- HOGENOM:   HBG335815
- OMA:   VIYLRAN
- PhylomeDB:   A1SRB6
- BioCyc:   PING357804:PING_0163-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00109
- InterPro:   IPR000623
- InterPro:   IPR023000
- PRINTS:   PR01100

Pfam domain/function: PF01202 SKI

EC number: =2.7.1.71

Molecular weight: Translated: 19183; Mature: 19052

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: BINDING 36-36 BINDING 60-60 BINDING 82-82 BINDING 120-120 BINDING 139-139 BINDING 156-156

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEQRNIFLIGPMGAGKSTIGRHLAQMLHLDFLDSDAEIEKKTGADIAWVFDVEGEEGFR
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEEEEECCCCCCHH
NREQSMIDELTQKHGIVLATGGGALIRPENRIHLSARGIVVYLKTSVNKQLARTLKDKRR
HHHHHHHHHHHHHCCEEEEECCCEEECCCCEEEEEECEEEEEEECHHHHHHHHHHHHHCC
PLLQTDDPRTVLEALAEKRNEFYDEVADYTMETDEQSAKVVASQIIALLDF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AEQRNIFLIGPMGAGKSTIGRHLAQMLHLDFLDSDAEIEKKTGADIAWVFDVEGEEGFR
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEEEEECCCCCCHH
NREQSMIDELTQKHGIVLATGGGALIRPENRIHLSARGIVVYLKTSVNKQLARTLKDKRR
HHHHHHHHHHHHHCCEEEEECCCEEECCCCEEEEEECEEEEEEECHHHHHHHHHHHHHCC
PLLQTDDPRTVLEALAEKRNEFYDEVADYTMETDEQSAKVVASQIIALLDF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA