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The map label for this gene is uxaC [H]

Identifier: 119943921

GI number: 119943921

Start: 171998

End: 173431

Strand: Reverse

Name: uxaC [H]

Synonym: Ping_0131

Alternate gene names: 119943921

Gene position: 173431-171998 (Counterclockwise)

Preceding gene: 119943922

Following gene: 119943920

Centisome position: 3.8

GC content: 43.58

Gene sequence:

>1434_bases
ATGGAGTCATCTATGAAAGCTTTTCTATGTGAAGATTTTCTTCTCAACAATAATGTAGCACGTCGTTTATACCATGACTT
CGCGAAAGACATGCCTATCTATGATTATCACTGTCATTTAAATGCGCAGGAAGTTGCCGATAACCGTCAATTTGATAACC
TTGGACAAATGTGGCTCGAAGGCGATCACTACAAATGGCGAGGCATGCGTACAGCAGGCATCAGCGAATCATTAATCACA
GGCAAAGATACCTCTGATTTTGAAAAATACATGGCATGGGCAAAAACAGTACCGCAAACACTTGGTAATCCTCTATACCA
TTGGACACACCTAGAATTACGCCGTCCCTTTGGCATAACGGGAAAATTATTTAATCCCGACACCGCTGAAGTTATCTGGC
ATGAGTGTAACGAAATGCTTGCCACGCCAGAATTTTCAGCTCGCGGCATAATGAAAAAAATGAACGTGGTAATGGCTGGC
ACAACTGATGATCCTATTCACTCCCTAGAGCACCACAAAGCTATTGCCGAAGATCCAGCCTGTGATATTGAAGTGGCACC
AAGCTGGCGTCCGGATCGCGCTTTTAAAATTGAGATCGAAGGCTTTAGTGAATATATGCGCCTGTTAGGCGAAGTAACTG
ACATTGAAATCGGCAGATTTTCTGATCTCCTCAGTGCATTAGAGCAGCGTATTGAGCACTTTTCGGCTCATGGTTGCCGT
GCAGCAGATCACGGTATTGAAGTGGTTCGTTACGCTACAGTACCAGTAGAATCAACGCTTGATTCTATTTTAACTCGCCG
TCTAAGTCAGCAAACACTGACCGAACAAGAGATAGATCAATTTACAACTGCTGTTCAGATTTGGTTGGGCACTCAATATG
CTAAACGTGGCTGGGTAATGCAATTGCACATTGGTGCACAACGTAATAATAATACCCGCATGTTTAAGCTGTTAGGGCCA
GATAGTGGTTTTGACTCAATTGGGGATCGACCCTTTGCATTACAATTAGGCGCTTTACTTGATGCCATGGATATCACTAA
TGAGTTGCCAAAAACTATTCTTTACTGCTTAAACCCTCGTGATAACGAAATGCTGGCTACCATGATGGGTAACTACCAAG
GTGGCGGTATTGCCGGAAAAATTCAATTCGGCTCAGGTTGGTGGTTCAACGATCAAAAGGACGGTATGCAGCGCCAAATG
CAGCAGCTATCGCAATTAGGGTTACTCAGCAAGTTTGTGGGTATGTTAACCGATTCCCGCAGCTTCTTATCTTATACTCG
CCATGAATATTTCCGTCGTATTTTATGTAATATGGTTGGTCAGTGGGTAGAGGACGGTGAAGCGCCAAATGATATAGCAA
TGCTTGGTAAGCTGATACAAGATGTTGCTTTTAACAACGCTAAAACCTACTTCAAGTTACCTGGGGAGCAGTGA

Upstream 100 bases:

>100_bases
GCTTACCAGCTTATTGTAACAAAAGGCGCGCGCGCTGCCGTCGCATCACTTTAAATATTTGATATCCCCACGCTGCTGAT
TGGCGTTGGGGATATTTTTT

Downstream 100 bases:

>100_bases
TGAAACGTCTCGCAATTATTGGCGAATGCATGATTGAGCTAAGTGGCAGTCCATTCGGCGCAATGCAGCAGACCTATGGT
GGTGATTCTCTCAATACGGC

Product: glucuronate isomerase

Products: NA

Alternate protein names: Glucuronate isomerase; Uronic isomerase [H]

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MESSMKAFLCEDFLLNNNVARRLYHDFAKDMPIYDYHCHLNAQEVADNRQFDNLGQMWLEGDHYKWRGMRTAGISESLIT
GKDTSDFEKYMAWAKTVPQTLGNPLYHWTHLELRRPFGITGKLFNPDTAEVIWHECNEMLATPEFSARGIMKKMNVVMAG
TTDDPIHSLEHHKAIAEDPACDIEVAPSWRPDRAFKIEIEGFSEYMRLLGEVTDIEIGRFSDLLSALEQRIEHFSAHGCR
AADHGIEVVRYATVPVESTLDSILTRRLSQQTLTEQEIDQFTTAVQIWLGTQYAKRGWVMQLHIGAQRNNNTRMFKLLGP
DSGFDSIGDRPFALQLGALLDAMDITNELPKTILYCLNPRDNEMLATMMGNYQGGGIAGKIQFGSGWWFNDQKDGMQRQM
QQLSQLGLLSKFVGMLTDSRSFLSYTRHEYFRRILCNMVGQWVEDGEAPNDIAMLGKLIQDVAFNNAKTYFKLPGEQ

Sequences:

>Translated_477_residues
MESSMKAFLCEDFLLNNNVARRLYHDFAKDMPIYDYHCHLNAQEVADNRQFDNLGQMWLEGDHYKWRGMRTAGISESLIT
GKDTSDFEKYMAWAKTVPQTLGNPLYHWTHLELRRPFGITGKLFNPDTAEVIWHECNEMLATPEFSARGIMKKMNVVMAG
TTDDPIHSLEHHKAIAEDPACDIEVAPSWRPDRAFKIEIEGFSEYMRLLGEVTDIEIGRFSDLLSALEQRIEHFSAHGCR
AADHGIEVVRYATVPVESTLDSILTRRLSQQTLTEQEIDQFTTAVQIWLGTQYAKRGWVMQLHIGAQRNNNTRMFKLLGP
DSGFDSIGDRPFALQLGALLDAMDITNELPKTILYCLNPRDNEMLATMMGNYQGGGIAGKIQFGSGWWFNDQKDGMQRQM
QQLSQLGLLSKFVGMLTDSRSFLSYTRHEYFRRILCNMVGQWVEDGEAPNDIAMLGKLIQDVAFNNAKTYFKLPGEQ
>Mature_477_residues
MESSMKAFLCEDFLLNNNVARRLYHDFAKDMPIYDYHCHLNAQEVADNRQFDNLGQMWLEGDHYKWRGMRTAGISESLIT
GKDTSDFEKYMAWAKTVPQTLGNPLYHWTHLELRRPFGITGKLFNPDTAEVIWHECNEMLATPEFSARGIMKKMNVVMAG
TTDDPIHSLEHHKAIAEDPACDIEVAPSWRPDRAFKIEIEGFSEYMRLLGEVTDIEIGRFSDLLSALEQRIEHFSAHGCR
AADHGIEVVRYATVPVESTLDSILTRRLSQQTLTEQEIDQFTTAVQIWLGTQYAKRGWVMQLHIGAQRNNNTRMFKLLGP
DSGFDSIGDRPFALQLGALLDAMDITNELPKTILYCLNPRDNEMLATMMGNYQGGGIAGKIQFGSGWWFNDQKDGMQRQM
QQLSQLGLLSKFVGMLTDSRSFLSYTRHEYFRRILCNMVGQWVEDGEAPNDIAMLGKLIQDVAFNNAKTYFKLPGEQ

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1904

COG function: function code G; Glucuronate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uronate isomerase family [H]

Homologues:

Organism=Escherichia coli, GI2367192, Length=469, Percent_Identity=65.6716417910448, Blast_Score=669, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003766
- InterPro:   IPR023177 [H]

Pfam domain/function: PF02614 UxaC [H]

EC number: =5.3.1.12 [H]

Molecular weight: Translated: 54481; Mature: 54481

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESSMKAFLCEDFLLNNNVARRLYHDFAKDMPIYDYHCHLNAQEVADNRQFDNLGQMWLE
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCHHHHHHHHCC
GDHYKWRGMRTAGISESLITGKDTSDFEKYMAWAKTVPQTLGNPLYHWTHLELRRPFGIT
CCCEEECCEEECCCCCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCC
GKLFNPDTAEVIWHECNEMLATPEFSARGIMKKMNVVMAGTTDDPIHSLEHHKAIAEDPA
CCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHCCCCC
CDIEVAPSWRPDRAFKIEIEGFSEYMRLLGEVTDIEIGRFSDLLSALEQRIEHFSAHGCR
CCEEECCCCCCCCEEEEEECCHHHHHHHHHCHHCCCHHHHHHHHHHHHHHHHHHHCCCCC
AADHGIEVVRYATVPVESTLDSILTRRLSQQTLTEQEIDQFTTAVQIWLGTQYAKRGWVM
CHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEE
QLHIGAQRNNNTRMFKLLGPDSGFDSIGDRPFALQLGALLDAMDITNELPKTILYCLNPR
EEEECCCCCCCCEEEEEECCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCC
DNEMLATMMGNYQGGGIAGKIQFGSGWWFNDQKDGMQRQMQQLSQLGLLSKFVGMLTDSR
CCHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCH
SFLSYTRHEYFRRILCNMVGQWVEDGEAPNDIAMLGKLIQDVAFNNAKTYFKLPGEQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCC
>Mature Secondary Structure
MESSMKAFLCEDFLLNNNVARRLYHDFAKDMPIYDYHCHLNAQEVADNRQFDNLGQMWLE
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCHHHHHHHHCC
GDHYKWRGMRTAGISESLITGKDTSDFEKYMAWAKTVPQTLGNPLYHWTHLELRRPFGIT
CCCEEECCEEECCCCCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCC
GKLFNPDTAEVIWHECNEMLATPEFSARGIMKKMNVVMAGTTDDPIHSLEHHKAIAEDPA
CCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHCCCCC
CDIEVAPSWRPDRAFKIEIEGFSEYMRLLGEVTDIEIGRFSDLLSALEQRIEHFSAHGCR
CCEEECCCCCCCCEEEEEECCHHHHHHHHHCHHCCCHHHHHHHHHHHHHHHHHHHCCCCC
AADHGIEVVRYATVPVESTLDSILTRRLSQQTLTEQEIDQFTTAVQIWLGTQYAKRGWVM
CHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEE
QLHIGAQRNNNTRMFKLLGPDSGFDSIGDRPFALQLGALLDAMDITNELPKTILYCLNPR
EEEECCCCCCCCEEEEEECCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCC
DNEMLATMMGNYQGGGIAGKIQFGSGWWFNDQKDGMQRQMQQLSQLGLLSKFVGMLTDSR
CCHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCH
SFLSYTRHEYFRRILCNMVGQWVEDGEAPNDIAMLGKLIQDVAFNNAKTYFKLPGEQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]