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The map label for this gene is uspA [H]

Identifier: 119943916

GI number: 119943916

Start: 167753

End: 168175

Strand: Direct

Name: uspA [H]

Synonym: Ping_0125

Alternate gene names: 119943916

Gene position: 167753-168175 (Clockwise)

Preceding gene: 119943915

Following gene: 119943925

Centisome position: 3.68

GC content: 35.22

Gene sequence:

>423_bases
ATGAGCTATAAGCATATATTAGTCGCTGTTGATTTATCTGAATCCAGCGAAAAAGTAATCAATAAAGCTGTCTCGTTAGC
TAAAGATGCAAAGGCTAACCTTTCATTAATTTTTGTTGATGATATTGCTAACATAGGGGTTGTAACTATAGAAGTTGCAC
CTCTACCTTCGGTTGAGGAGAGAGAAAAAAAATTAAAAGGTGAATTGCAGGAATTAGCTGATAAGGCTGATTATCAGTTT
GACAATATCATAGTTGTGACGGAGGATTTGAAGAATAAACTTGTAGCAACAGTTAAAAAAATGAATATTGATTTATTGGT
TTGCGGCCATCACCGTGATTTCTGGAGTCGACTATTATCTTCTGTGCGTAAGCTGATCAATTCTGTGGCTGCTGATCTAT
TGATTGTTAATCTCGATGAATAA

Upstream 100 bases:

>100_bases
GGGGGTAAATGCCAAACTGATCCGGTGTTGTTATAGAGAGTGATTAAGCCGTCGGATTAAAAGATGTTTTTTTATTAATA
GGGTTAATTGTGAGGACGCT

Downstream 100 bases:

>100_bases
GTAGCAGATCTTGTTCTATTTTGATGTGTGGCGGCTGCGTTTCACTGTGAGTCATGAAATCAATAAAAACGGATATTGTT
TTTTTTTCCTAAGAAAGCAC

Product: universal stress protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 140; Mature: 139

Protein sequence:

>140_residues
MSYKHILVAVDLSESSEKVINKAVSLAKDAKANLSLIFVDDIANIGVVTIEVAPLPSVEEREKKLKGELQELADKADYQF
DNIIVVTEDLKNKLVATVKKMNIDLLVCGHHRDFWSRLLSSVRKLINSVAADLLIVNLDE

Sequences:

>Translated_140_residues
MSYKHILVAVDLSESSEKVINKAVSLAKDAKANLSLIFVDDIANIGVVTIEVAPLPSVEEREKKLKGELQELADKADYQF
DNIIVVTEDLKNKLVATVKKMNIDLLVCGHHRDFWSRLLSSVRKLINSVAADLLIVNLDE
>Mature_139_residues
SYKHILVAVDLSESSEKVINKAVSLAKDAKANLSLIFVDDIANIGVVTIEVAPLPSVEEREKKLKGELQELADKADYQFD
NIIVVTEDLKNKLVATVKKMNIDLLVCGHHRDFWSRLLSSVRKLINSVAADLLIVNLDE

Specific function: Required for resistance to DNA-damaging agents [H]

COG id: COG0589

COG function: function code T; Universal stress protein UspA and related nucleotide-binding proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the universal stress protein A family [H]

Homologues:

Organism=Escherichia coli, GI1789909, Length=143, Percent_Identity=43.3566433566434, Blast_Score=109, Evalue=6e-26,
Organism=Escherichia coli, GI1790358, Length=143, Percent_Identity=34.965034965035, Blast_Score=78, Evalue=2e-16,
Organism=Escherichia coli, GI1788205, Length=143, Percent_Identity=32.1678321678322, Blast_Score=69, Evalue=9e-14,

Paralogues:

None

Copy number: 1660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 290 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 4003 Molecules/Cell In: Growth Phase, G

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014729
- InterPro:   IPR006016 [H]

Pfam domain/function: PF00582 Usp [H]

EC number: NA

Molecular weight: Translated: 15569; Mature: 15438

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYKHILVAVDLSESSEKVINKAVSLAKDAKANLSLIFVDDIANIGVVTIEVAPLPSVEE
CCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEECCCCCHHH
REKKLKGELQELADKADYQFDNIIVVTEDLKNKLVATVKKMNIDLLVCGHHRDFWSRLLS
HHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHH
SVRKLINSVAADLLIVNLDE
HHHHHHHHHHHHEEEEEECC
>Mature Secondary Structure 
SYKHILVAVDLSESSEKVINKAVSLAKDAKANLSLIFVDDIANIGVVTIEVAPLPSVEE
CCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEECCCCCHHH
REKKLKGELQELADKADYQFDNIIVVTEDLKNKLVATVKKMNIDLLVCGHHRDFWSRLLS
HHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHH
SVRKLINSVAADLLIVNLDE
HHHHHHHHHHHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]