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The map label for this gene is metA

Identifier: 119943905

GI number: 119943905

Start: 143670

End: 144587

Strand: Direct

Name: metA

Synonym: Ping_0112

Alternate gene names: 119943905

Gene position: 143670-144587 (Clockwise)

Preceding gene: 119943903

Following gene: 119943906

Centisome position: 3.15

GC content: 40.09

Gene sequence:

>918_bases
ATGCCAATTCGTATTTCTGATGATCTGCCAGCTGCTGATATTTTAAGGTCAGAAAATATTTTTACTATGTCTGAATCGCG
CGCTAGCCTTCAGAATATCCGTCCTTTACGTGTTTTGATTCTTAATTTGATGCCGAAAAAAATTGAAACAGAAACACAAA
TAATGCGTTTGTTATCTAATACACCATTACAAGTAAATGTTGAATTAATACGAGTAGATGCCCGCGCATCACGCAACACC
CCGAAAGAGCACTTAGACAAATTTTACAGTGATTTTGACCGAGTCAAAAATCAAAAGTGGGATGGTTTTGTGATTACCGG
GGCACCACTAGGACAGCTTCCCTTTGAAGATGTTTACTATTGGGAAAAGTTTGTCGAAATTGTTGAATGGTCACGCCATA
ATGTAACCTCAACACTCTTTTTGTGTTGGGCTGCGCAGGCTGCTTTAACCTATTTATATGGCTTAAAGAAAGAAACACGG
GGAGATAAACTGTCTGGTATTTATTTACACCGTACCCATCACCATCATCACCCTCTAGTACGCGGATTTGATGATGAATT
TTGGGCTCCATTATCTCGTTTTGCTGAATTTAATTCAGAGGTGGTCTCTGAAAATAGTGATTTAACTATTTTTGCAGATG
CACCCAATGCGGGTATTTATTTGGCCGCCAGCCCGGATTGTCGTCAGGTTTATGTTACCGGGCACCCGGAATATGATGCG
AGTACATTACATAATGAGTATTTACGCGATCTCGAAGAGGGGTTGGAGCCCAAACAGCCAGTGAATTATTATCCCGATAA
TGATCAGAATAAAACACCGCGGGCAATTTGGCGAAGTCATGGAAACTTATTATACAGCAACTGGTTAAACTATTGTGTTT
ATCAAGTGACACCCTATGACTTAGCCGATTTGATATAA

Upstream 100 bases:

>100_bases
TAATATCATTTAGAAGGATTTTTTAGCAGTATTAATAAAATTAGTGTTAGACTTCTGGATGTCCAAATAAAAATATATTC
TAATATGGGGTTTTAAAATT

Downstream 100 bases:

>100_bases
CAAGCCAATAAAAAATTGCCTTGGTAAATTTTTGATTATTTCAGTGGTGGTTTAATAGCACTACCAATAATAACTTCTAC
ACTTTAAATGTTAGCGGTAG

Product: homoserine O-succinyltransferase

Products: NA

Alternate protein names: Homoserine O-transsuccinylase; HTS

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MPIRISDDLPAADILRSENIFTMSESRASLQNIRPLRVLILNLMPKKIETETQIMRLLSNTPLQVNVELIRVDARASRNT
PKEHLDKFYSDFDRVKNQKWDGFVITGAPLGQLPFEDVYYWEKFVEIVEWSRHNVTSTLFLCWAAQAALTYLYGLKKETR
GDKLSGIYLHRTHHHHHPLVRGFDDEFWAPLSRFAEFNSEVVSENSDLTIFADAPNAGIYLAASPDCRQVYVTGHPEYDA
STLHNEYLRDLEEGLEPKQPVNYYPDNDQNKTPRAIWRSHGNLLYSNWLNYCVYQVTPYDLADLI

Sequences:

>Translated_305_residues
MPIRISDDLPAADILRSENIFTMSESRASLQNIRPLRVLILNLMPKKIETETQIMRLLSNTPLQVNVELIRVDARASRNT
PKEHLDKFYSDFDRVKNQKWDGFVITGAPLGQLPFEDVYYWEKFVEIVEWSRHNVTSTLFLCWAAQAALTYLYGLKKETR
GDKLSGIYLHRTHHHHHPLVRGFDDEFWAPLSRFAEFNSEVVSENSDLTIFADAPNAGIYLAASPDCRQVYVTGHPEYDA
STLHNEYLRDLEEGLEPKQPVNYYPDNDQNKTPRAIWRSHGNLLYSNWLNYCVYQVTPYDLADLI
>Mature_304_residues
PIRISDDLPAADILRSENIFTMSESRASLQNIRPLRVLILNLMPKKIETETQIMRLLSNTPLQVNVELIRVDARASRNTP
KEHLDKFYSDFDRVKNQKWDGFVITGAPLGQLPFEDVYYWEKFVEIVEWSRHNVTSTLFLCWAAQAALTYLYGLKKETRG
DKLSGIYLHRTHHHHHPLVRGFDDEFWAPLSRFAEFNSEVVSENSDLTIFADAPNAGIYLAASPDCRQVYVTGHPEYDAS
TLHNEYLRDLEEGLEPKQPVNYYPDNDQNKTPRAIWRSHGNLLYSNWLNYCVYQVTPYDLADLI

Specific function: Methionine biosynthesis; HTS variant; first step. [C]

COG id: COG1897

COG function: function code E; Homoserine trans-succinylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTS family

Homologues:

Organism=Escherichia coli, GI1790443, Length=301, Percent_Identity=59.1362126245847, Blast_Score=389, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): META_PSYIN (A1SR71)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_941585.1
- ProteinModelPortal:   A1SR71
- SMR:   A1SR71
- STRING:   A1SR71
- GeneID:   4626181
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_0112
- eggNOG:   COG1897
- HOGENOM:   HBG362506
- OMA:   QAGLYYH
- PhylomeDB:   A1SR71
- BioCyc:   PING357804:PING_0112-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00295
- InterPro:   IPR005697
- PANTHER:   PTHR20919
- PIRSF:   PIRSF000450
- ProDom:   PD037892
- TIGRFAMs:   TIGR01001

Pfam domain/function: PF04204 HTS

EC number: =2.3.1.46

Molecular weight: Translated: 35393; Mature: 35262

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: ACT_SITE 142-142

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIRISDDLPAADILRSENIFTMSESRASLQNIRPLRVLILNLMPKKIETETQIMRLLSN
CCEEECCCCCHHHHHCCCCEEEECHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHCC
TPLQVNVELIRVDARASRNTPKEHLDKFYSDFDRVKNQKWDGFVITGAPLGQLPFEDVYY
CCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHH
WEKFVEIVEWSRHNVTSTLFLCWAAQAALTYLYGLKKETRGDKLSGIYLHRTHHHHHPLV
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCC
RGFDDEFWAPLSRFAEFNSEVVSENSDLTIFADAPNAGIYLAASPDCRQVYVTGHPEYDA
CCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCCCEEEEECCCCCCH
STLHNEYLRDLEEGLEPKQPVNYYPDNDQNKTPRAIWRSHGNLLYSNWLNYCVYQVTPYD
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCEEHHHHHHHEEEECCCHH
LADLI
HHHCC
>Mature Secondary Structure 
PIRISDDLPAADILRSENIFTMSESRASLQNIRPLRVLILNLMPKKIETETQIMRLLSN
CEEECCCCCHHHHHCCCCEEEECHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHCC
TPLQVNVELIRVDARASRNTPKEHLDKFYSDFDRVKNQKWDGFVITGAPLGQLPFEDVYY
CCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHH
WEKFVEIVEWSRHNVTSTLFLCWAAQAALTYLYGLKKETRGDKLSGIYLHRTHHHHHPLV
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCC
RGFDDEFWAPLSRFAEFNSEVVSENSDLTIFADAPNAGIYLAASPDCRQVYVTGHPEYDA
CCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCCCEEEEECCCCCCH
STLHNEYLRDLEEGLEPKQPVNYYPDNDQNKTPRAIWRSHGNLLYSNWLNYCVYQVTPYD
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCEEHHHHHHHEEEECCCHH
LADLI
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA