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The map label for this gene is coaD

Identifier: 119943836

GI number: 119943836

Start: 61851

End: 62336

Strand: Direct

Name: coaD

Synonym: Ping_0043

Alternate gene names: 119943836

Gene position: 61851-62336 (Clockwise)

Preceding gene: 119943835

Following gene: 119943837

Centisome position: 1.36

GC content: 41.36

Gene sequence:

>486_bases
ATGAAAACAGTTGTTTTTCCCGGTTCATTTGATCCGGTCACATTAGGTCATATTGATCTGATCACCAGAGCCAGTAAACT
AGCGGAAAGAGTTGTTATTGCTGTGGCGGTGAACACCAGTAAAAGAACTTTGTTTAATTTAAATGAGCGCTGTGATTTAT
TATCCGAAGCAACGGCTCATTTAAGCGGCATTGAAGTGATTCCTTTCTCGGGTTTATTGGCAGATTTTGCTAAAGAGCAT
AATGCACAAGCGCTTATTCGCGGGATACGTGGTACGACAGACGCTGATTATGAATTACAACTGGCGCAAGTGAATAAAGC
ATTAAACTCAGAATTAGAAACCATTTTGTTACCCGCCAATGCCGCAACCGGTTTTATCTCATCAACCGTAGTTAAAGAGG
TGTTCAAGCATAATGGGGATATTGACCCGTTTGCGCCACCCTGTGTGAAACAAGCGTTATTGATAAAACACTCCGAGAAT
AGTTAA

Upstream 100 bases:

>100_bases
GTTCTGCTCGTGAAGGTTTAAATAAAATTAATGATGCTGTGGTTAAGTAAATACAACTAAGTAAATATAGTTAAGTAAAT
ATAATAATGGTTGAATCAAT

Downstream 100 bases:

>100_bases
TTCAATACACCGACCTGCCTTCGGTATTTTTTCTCCCTAGCACACTAAGCTTAGCCTGCTGATCATCCTAAGCTACCTAG
CCAGTTTAGTTTGTTTGCAG

Product: pantetheine-phosphate adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MKTVVFPGSFDPVTLGHIDLITRASKLAERVVIAVAVNTSKRTLFNLNERCDLLSEATAHLSGIEVIPFSGLLADFAKEH
NAQALIRGIRGTTDADYELQLAQVNKALNSELETILLPANAATGFISSTVVKEVFKHNGDIDPFAPPCVKQALLIKHSEN
S

Sequences:

>Translated_161_residues
MKTVVFPGSFDPVTLGHIDLITRASKLAERVVIAVAVNTSKRTLFNLNERCDLLSEATAHLSGIEVIPFSGLLADFAKEH
NAQALIRGIRGTTDADYELQLAQVNKALNSELETILLPANAATGFISSTVVKEVFKHNGDIDPFAPPCVKQALLIKHSEN
S
>Mature_161_residues
MKTVVFPGSFDPVTLGHIDLITRASKLAERVVIAVAVNTSKRTLFNLNERCDLLSEATAHLSGIEVIPFSGLLADFAKEH
NAQALIRGIRGTTDADYELQLAQVNKALNSELETILLPANAATGFISSTVVKEVFKHNGDIDPFAPPCVKQALLIKHSEN
S

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=155, Percent_Identity=47.0967741935484, Blast_Score=162, Evalue=8e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_PSYIN (A1SR02)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_941516.1
- ProteinModelPortal:   A1SR02
- SMR:   A1SR02
- STRING:   A1SR02
- GeneID:   4623535
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_0043
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- PhylomeDB:   A1SR02
- BioCyc:   PING357804:PING_0043-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17393; Mature: 17393

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVVFPGSFDPVTLGHIDLITRASKLAERVVIAVAVNTSKRTLFNLNERCDLLSEATAH
CCEEECCCCCCCEEEHHHHHHHHHHHHHHHEEEEEEECCCCHHEECCHHHHHHHHHHHHH
LSGIEVIPFSGLLADFAKEHNAQALIRGIRGTTDADYELQLAQVNKALNSELETILLPAN
HCCCEEECCHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEHHHHHHHHHHCCCCEEEEECC
AATGFISSTVVKEVFKHNGDIDPFAPPCVKQALLIKHSENS
CHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHEECCCC
>Mature Secondary Structure
MKTVVFPGSFDPVTLGHIDLITRASKLAERVVIAVAVNTSKRTLFNLNERCDLLSEATAH
CCEEECCCCCCCEEEHHHHHHHHHHHHHHHEEEEEEECCCCHHEECCHHHHHHHHHHHHH
LSGIEVIPFSGLLADFAKEHNAQALIRGIRGTTDADYELQLAQVNKALNSELETILLPAN
HCCCEEECCHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEHHHHHHHHHHCCCCEEEEECC
AATGFISSTVVKEVFKHNGDIDPFAPPCVKQALLIKHSENS
CHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA