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The map label for this gene is qor [H]

Identifier: 119871444

GI number: 119871444

Start: 5652432

End: 5653406

Strand: Direct

Name: qor [H]

Synonym: Mkms_5420

Alternate gene names: 119871444

Gene position: 5652432-5653406 (Clockwise)

Preceding gene: 119871443

Following gene: 119871449

Centisome position: 98.52

GC content: 69.64

Gene sequence:

>975_bases
ATGCGCCGCCTGCCGTGGTTGCACCGCATGGACCACCTCAACCGATGGGAGACAGGCATGGCACGCGCCGCGCAGTTCGC
CGAGTACGGCGACCCCGACGTCCTGAAACTGGTCGACGCACCGCCCCCGACGCCCGGGCCGGGGCAGGTACGCATCTCGG
TGCGAGCCGCCGGCGTCAACCCCATCGACTGGAAGATCGTCGCGGGTTTCATGCGAGAGCAGATCCCCCTGCAGCTGCCC
GCCGGAACGGGGTCGGACGTTGCCGGGGTCGTCGACGAAATCGGCTCTGGCGTAACGGAATGGACTATCGGAGACGAGGT
GCTGGGTGTCTCGGCGACACCGTCGTTCGCCGAGTACGCCGTGGCCGGCGCGGGTGACCTCGTCCGCAAACCCGACGGTA
TGAGCTGGGAGGTGGCCGGTTCTCTTGCAGGTGCGGGCGGCACCGCCTACACCGTGCTGCAGAAACTCGGGGTGCGAGCC
GGTGACACGCTGCTCGTCCACGCGGCGGCGGGTGGTGTCGGGACGTTCGCCGTCCAACTCGCCACAGCCCGGGGCGCCCG
CGTCGTCGGCACGGCGAGCGAACGCAACCACGAGTACCTGCGGTCGATCGGTGCGACACCGGTCGACTACGGCGACGGGC
TGATCGACCGGGTGCGCGCGGCCGCCCCGCAGGGAGTCGACGCCGTACTCGACGCCTCCGGTCGCGGCGAGATACCGATG
TCGATCGAGCTCACCGGAGACCCCGCCCGTGTCCTCTCACTGGTGGCGTTCGACGCCGCCGATACGGGCATCCAACTGCA
TGTCGGCGGTGCGGGAAGCGTTCTCGGAGAGGCCCTTCGCGAACTCGTCACGCTCATCGACCGGGGCCGCCTCACCGTCG
CCGTCAGCCGCACCTATCCGCTCGAGGAGGTCGTCGCCGCCCTGGACGAGAGTCGCGCGGGGCATCTCAACGGGAAGATC
GTCATCGTGCCGTGA

Upstream 100 bases:

>100_bases
ACCCGACGTGGGTCCTGCGGTTCGTCGCTGCGCGGGAGGACCGGCTCAGCGGGCTCTCCAAACGGGAGGCGCGCAAGCAC
CTGCTACCTGCCGCGGAGTA

Downstream 100 bases:

>100_bases
GCGTCGGAGCCCACGGTGCGCTCCGCTACGTGTGCTCGCGCAGGTCGGCGACCTGGTATGCGTTGTCCGCGTAGCGCGCC
CGGATCACCTTCTTGTCGTA

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MRRLPWLHRMDHLNRWETGMARAAQFAEYGDPDVLKLVDAPPPTPGPGQVRISVRAAGVNPIDWKIVAGFMREQIPLQLP
AGTGSDVAGVVDEIGSGVTEWTIGDEVLGVSATPSFAEYAVAGAGDLVRKPDGMSWEVAGSLAGAGGTAYTVLQKLGVRA
GDTLLVHAAAGGVGTFAVQLATARGARVVGTASERNHEYLRSIGATPVDYGDGLIDRVRAAAPQGVDAVLDASGRGEIPM
SIELTGDPARVLSLVAFDAADTGIQLHVGGAGSVLGEALRELVTLIDRGRLTVAVSRTYPLEEVVAALDESRAGHLNGKI
VIVP

Sequences:

>Translated_324_residues
MRRLPWLHRMDHLNRWETGMARAAQFAEYGDPDVLKLVDAPPPTPGPGQVRISVRAAGVNPIDWKIVAGFMREQIPLQLP
AGTGSDVAGVVDEIGSGVTEWTIGDEVLGVSATPSFAEYAVAGAGDLVRKPDGMSWEVAGSLAGAGGTAYTVLQKLGVRA
GDTLLVHAAAGGVGTFAVQLATARGARVVGTASERNHEYLRSIGATPVDYGDGLIDRVRAAAPQGVDAVLDASGRGEIPM
SIELTGDPARVLSLVAFDAADTGIQLHVGGAGSVLGEALRELVTLIDRGRLTVAVSRTYPLEEVVAALDESRAGHLNGKI
VIVP
>Mature_324_residues
MRRLPWLHRMDHLNRWETGMARAAQFAEYGDPDVLKLVDAPPPTPGPGQVRISVRAAGVNPIDWKIVAGFMREQIPLQLP
AGTGSDVAGVVDEIGSGVTEWTIGDEVLGVSATPSFAEYAVAGAGDLVRKPDGMSWEVAGSLAGAGGTAYTVLQKLGVRA
GDTLLVHAAAGGVGTFAVQLATARGARVVGTASERNHEYLRSIGATPVDYGDGLIDRVRAAAPQGVDAVLDASGRGEIPM
SIELTGDPARVLSLVAFDAADTGIQLHVGGAGSVLGEALRELVTLIDRGRLTVAVSRTYPLEEVVAALDESRAGHLNGKI
VIVP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=241, Percent_Identity=33.195020746888, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI13236495, Length=241, Percent_Identity=33.195020746888, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI194239676, Length=213, Percent_Identity=35.6807511737089, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI18379349, Length=313, Percent_Identity=29.3929712460064, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI24308257, Length=213, Percent_Identity=31.4553990610329, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI47519420, Length=348, Percent_Identity=27.2988505747126, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI28557745, Length=252, Percent_Identity=30.1587301587302, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI90669511, Length=208, Percent_Identity=31.7307692307692, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI22538446, Length=225, Percent_Identity=30.2222222222222, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI22538444, Length=225, Percent_Identity=30.2222222222222, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI1790485, Length=332, Percent_Identity=29.5180722891566, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI226510941, Length=230, Percent_Identity=27.8260869565217, Blast_Score=61, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17507255, Length=309, Percent_Identity=32.6860841423948, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71987554, Length=212, Percent_Identity=30.188679245283, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17556000, Length=191, Percent_Identity=28.7958115183246, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=230, Percent_Identity=30.8695652173913, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323729, Length=336, Percent_Identity=25.297619047619, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324486, Length=199, Percent_Identity=30.6532663316583, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323961, Length=184, Percent_Identity=31.5217391304348, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6319621, Length=184, Percent_Identity=29.3478260869565, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24581341, Length=358, Percent_Identity=26.8156424581006, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24581339, Length=358, Percent_Identity=26.8156424581006, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 33646; Mature: 33646

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLPWLHRMDHLNRWETGMARAAQFAEYGDPDVLKLVDAPPPTPGPGQVRISVRAAGVN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEEEEECCCC
PIDWKIVAGFMREQIPLQLPAGTGSDVAGVVDEIGSGVTEWTIGDEVLGVSATPSFAEYA
CCHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHCCCCEEEECCCCEEECCCCCCHHHHH
VAGAGDLVRKPDGMSWEVAGSLAGAGGTAYTVLQKLGVRAGDTLLVHAAAGGVGTFAVQL
HCCCCHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEE
ATARGARVVGTASERNHEYLRSIGATPVDYGDGLIDRVRAAAPQGVDAVLDASGRGEIPM
ECCCCCEEEECCCCCCHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCHHEEECCCCCCCCE
SIELTGDPARVLSLVAFDAADTGIQLHVGGAGSVLGEALRELVTLIDRGRLTVAVSRTYP
EEEECCCHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEECCCC
LEEVVAALDESRAGHLNGKIVIVP
HHHHHHHHHCCCCCCCCCEEEEEC
>Mature Secondary Structure
MRRLPWLHRMDHLNRWETGMARAAQFAEYGDPDVLKLVDAPPPTPGPGQVRISVRAAGVN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEEEEECCCC
PIDWKIVAGFMREQIPLQLPAGTGSDVAGVVDEIGSGVTEWTIGDEVLGVSATPSFAEYA
CCHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHCCCCEEEECCCCEEECCCCCCHHHHH
VAGAGDLVRKPDGMSWEVAGSLAGAGGTAYTVLQKLGVRAGDTLLVHAAAGGVGTFAVQL
HCCCCHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEE
ATARGARVVGTASERNHEYLRSIGATPVDYGDGLIDRVRAAAPQGVDAVLDASGRGEIPM
ECCCCCEEEECCCCCCHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCHHEEECCCCCCCCE
SIELTGDPARVLSLVAFDAADTGIQLHVGGAGSVLGEALRELVTLIDRGRLTVAVSRTYP
EEEECCCHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEECCCC
LEEVVAALDESRAGHLNGKIVIVP
HHHHHHHHHCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]