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The map label for this gene is ribA [H]

Identifier: 119871306

GI number: 119871306

Start: 5514400

End: 5515680

Strand: Direct

Name: ribA [H]

Synonym: Mkms_5279

Alternate gene names: 119871306

Gene position: 5514400-5515680 (Clockwise)

Preceding gene: 119871305

Following gene: 119871307

Centisome position: 96.12

GC content: 68.23

Gene sequence:

>1281_bases
ATGCTGGCGCCTTTCCCCCTGAGGACGGGAGGCGCCATGTCGACTGGGAGCGGACACATCCGGTTGACGTCGCACAGCGG
TGCGGTGGGCACCCCGACGATCCACTGGGGTGCGCCCACCGCCGCCGAGCGCGGGCCGGTGATCGGGACGACCGCCAACC
GCTCGCACCGCAACGTCATCGGCACCCACAGCGGGTCCTACAGCGTCTACCGGGCACTGGCCGTCGCCGCGGGTGCGCTC
AAACGGGAGCACCGCGCCGACCTCACCGACACCTCGCCGACCGACACCATCGGCCCATACCCGCAGTGGGGTGAACCGGC
CACGATCGTCAGCATGGACCCGTGGGGCGCCAGTGTGGCCGACGTGTTCACCGCCGAACTCGCTGCGGGCCTCGACATCC
GGCCGACCATCGCGATCACCAAGGCGCATGTGATCCTGCCCGAGATCACCGACGCGATCGCCAAGGGCCGCCTGGTCCCC
GACGGGCGCGTCCTGCTCGCCAGCGGCGCCGCGCTGGTCACTAAGGCCGCCGTCGAACCCGTCTGGTGGCTGCCCGGGGT
GGCGCAGCGGTTCGGGTGCAGCGAGACTGATCTGCGCCGGGTGCTGTTCGAGGAGACCGGCGGGATGTACCCGGAACTCG
TCACCCGCTCCGACCTCGAGGTGTTCCTCCCGCCGATCGGCGGGCAGACCGTCTACATCTTCGGCAGCGCAACCGATCTC
GCCGATCCGTCGGTCGAGTTGACCGCCCGCGTACACGACGAGTGCAACGGCTCGGACGTCTTCGGGTCCGACATCTGCAC
GTGCAGGCCGTATCTCACGCATGCGATCGAGGAGTGCATCCGCGGCGCCCAGAACGGTGGCGTCGGCCTGGTCGCCTACT
CCCGCAAGGAGGGCCGCGCGCTGGGTGAGGTCACCAAGTTCCTGGTGTACAACGCCCGCAAGCGTCAGGTCGGCGGCGAC
ACCGCCGATCAGTACTTCGCGCGCACCGAATGTGTGGCCGGCGTCCAGGACATGCGCTTCCAGGAACTGATGCCCGACGT
GCTGCACTGGTTCGGTATCCGCAAGATCCACCGCCTGGTGTCGATGAGCAACATGAAGTACGACGCGATCACCGGGTCGG
GAATCGAAGTGGGAGAACGGGTCAACATCCCCGAGGAACTCATCCCTCCGGATGCGCGGGTGGAGATCGACGCCAAGATG
GCGGCCGGTTACTTCACCCCGGGCCCGGTGCCCGACGCCGAGAAACTCAAGCAGGTCAAGGGTCGCGGGTTGTCGCAGTG
A

Upstream 100 bases:

>100_bases
CGACCTGGTACTCGACACCGCGACACCCGAACGCCTCCCGCGGGTGGCCGCCGGAGTCCCCGGCTGAGTCGACACCCGGC
ACGGGTGCCGGGGAATCGCT

Downstream 100 bases:

>100_bases
GTTCGGATACGCCGGAGGGTGCGGCGGCTGCGCTGCGCACCACCGACGCCGTCCGGGACCGCGCCGGCCGACTGCTGCAG
CGGGCCAGGGCGGGTGAGTC

Product: hypothetical protein

Products: NA

Alternate protein names: GTP cyclohydrolase II [H]

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MLAPFPLRTGGAMSTGSGHIRLTSHSGAVGTPTIHWGAPTAAERGPVIGTTANRSHRNVIGTHSGSYSVYRALAVAAGAL
KREHRADLTDTSPTDTIGPYPQWGEPATIVSMDPWGASVADVFTAELAAGLDIRPTIAITKAHVILPEITDAIAKGRLVP
DGRVLLASGAALVTKAAVEPVWWLPGVAQRFGCSETDLRRVLFEETGGMYPELVTRSDLEVFLPPIGGQTVYIFGSATDL
ADPSVELTARVHDECNGSDVFGSDICTCRPYLTHAIEECIRGAQNGGVGLVAYSRKEGRALGEVTKFLVYNARKRQVGGD
TADQYFARTECVAGVQDMRFQELMPDVLHWFGIRKIHRLVSMSNMKYDAITGSGIEVGERVNIPEELIPPDARVEIDAKM
AAGYFTPGPVPDAEKLKQVKGRGLSQ

Sequences:

>Translated_426_residues
MLAPFPLRTGGAMSTGSGHIRLTSHSGAVGTPTIHWGAPTAAERGPVIGTTANRSHRNVIGTHSGSYSVYRALAVAAGAL
KREHRADLTDTSPTDTIGPYPQWGEPATIVSMDPWGASVADVFTAELAAGLDIRPTIAITKAHVILPEITDAIAKGRLVP
DGRVLLASGAALVTKAAVEPVWWLPGVAQRFGCSETDLRRVLFEETGGMYPELVTRSDLEVFLPPIGGQTVYIFGSATDL
ADPSVELTARVHDECNGSDVFGSDICTCRPYLTHAIEECIRGAQNGGVGLVAYSRKEGRALGEVTKFLVYNARKRQVGGD
TADQYFARTECVAGVQDMRFQELMPDVLHWFGIRKIHRLVSMSNMKYDAITGSGIEVGERVNIPEELIPPDARVEIDAKM
AAGYFTPGPVPDAEKLKQVKGRGLSQ
>Mature_426_residues
MLAPFPLRTGGAMSTGSGHIRLTSHSGAVGTPTIHWGAPTAAERGPVIGTTANRSHRNVIGTHSGSYSVYRALAVAAGAL
KREHRADLTDTSPTDTIGPYPQWGEPATIVSMDPWGASVADVFTAELAAGLDIRPTIAITKAHVILPEITDAIAKGRLVP
DGRVLLASGAALVTKAAVEPVWWLPGVAQRFGCSETDLRRVLFEETGGMYPELVTRSDLEVFLPPIGGQTVYIFGSATDL
ADPSVELTARVHDECNGSDVFGSDICTCRPYLTHAIEECIRGAQNGGVGLVAYSRKEGRALGEVTKFLVYNARKRQVGGD
TADQYFARTECVAGVQDMRFQELMPDVLHWFGIRKIHRLVSMSNMKYDAITGSGIEVGERVNIPEELIPPDARVEIDAKM
AAGYFTPGPVPDAEKLKQVKGRGLSQ

Specific function: Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate [H]

COG id: COG0807

COG function: function code H; GTP cyclohydrolase II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase II family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000926 [H]

Pfam domain/function: PF00925 GTP_cyclohydro2 [H]

EC number: =3.5.4.25 [H]

Molecular weight: Translated: 45645; Mature: 45645

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAPFPLRTGGAMSTGSGHIRLTSHSGAVGTPTIHWGAPTAAERGPVIGTTANRSHRNVI
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEECCCCCCCCCCCEEEECCCCCCCCEE
GTHSGSYSVYRALAVAAGALKREHRADLTDTSPTDTIGPYPQWGEPATIVSMDPWGASVA
ECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHH
DVFTAELAAGLDIRPTIAITKAHVILPEITDAIAKGRLVPDGRVLLASGAALVTKAAVEP
HHHHHHHHCCCCCCCEEEEEEEEEECHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHCCC
VWWLPGVAQRFGCSETDLRRVLFEETGGMYPELVTRSDLEVFLPPIGGQTVYIFGSATDL
CCCCCCHHHHHCCCHHHHHHHHHHHCCCCCHHHHCCCCCEEEECCCCCCEEEEEECCCCC
ADPSVELTARVHDECNGSDVFGSDICTCRPYLTHAIEECIRGAQNGGVGLVAYSRKEGRA
CCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCHH
LGEVTKFLVYNARKRQVGGDTADQYFARTECVAGVQDMRFQELMPDVLHWFGIRKIHRLV
HHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
SMSNMKYDAITGSGIEVGERVNIPEELIPPDARVEIDAKMAAGYFTPGPVPDAEKLKQVK
HHCCCEEEEECCCCCCCCCCCCCCHHHCCCCCEEEEEEEHCCCCCCCCCCCCHHHHHHHH
GRGLSQ
CCCCCC
>Mature Secondary Structure
MLAPFPLRTGGAMSTGSGHIRLTSHSGAVGTPTIHWGAPTAAERGPVIGTTANRSHRNVI
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEECCCCCCCCCCCEEEECCCCCCCCEE
GTHSGSYSVYRALAVAAGALKREHRADLTDTSPTDTIGPYPQWGEPATIVSMDPWGASVA
ECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHH
DVFTAELAAGLDIRPTIAITKAHVILPEITDAIAKGRLVPDGRVLLASGAALVTKAAVEP
HHHHHHHHCCCCCCCEEEEEEEEEECHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHCCC
VWWLPGVAQRFGCSETDLRRVLFEETGGMYPELVTRSDLEVFLPPIGGQTVYIFGSATDL
CCCCCCHHHHHCCCHHHHHHHHHHHCCCCCHHHHCCCCCEEEECCCCCCEEEEEECCCCC
ADPSVELTARVHDECNGSDVFGSDICTCRPYLTHAIEECIRGAQNGGVGLVAYSRKEGRA
CCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCHH
LGEVTKFLVYNARKRQVGGDTADQYFARTECVAGVQDMRFQELMPDVLHWFGIRKIHRLV
HHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
SMSNMKYDAITGSGIEVGERVNIPEELIPPDARVEIDAKMAAGYFTPGPVPDAEKLKQVK
HHCCCEEEEECCCCCCCCCCCCCCHHHCCCCCEEEEEEEHCCCCCCCCCCCCHHHHHHHH
GRGLSQ
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA