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The map label for this gene is fadE25 [H]

Identifier: 119871304

GI number: 119871304

Start: 5512026

End: 5513216

Strand: Direct

Name: fadE25 [H]

Synonym: Mkms_5277

Alternate gene names: 119871304

Gene position: 5512026-5513216 (Clockwise)

Preceding gene: 119871301

Following gene: 119871305

Centisome position: 96.07

GC content: 70.11

Gene sequence:

>1191_bases
ATGAGCACCGCCGCTGATATCGATCGGGTCACCGAACTCGCCAACCGCGTCGTGGCCGAATACGATCCCAAGACCGTGCT
GATCCCCGAGTACCTCGGCGCCTGTTACGACGCCGGCCTGTCGTGGGTGCACTTCCCGGAGGGGCTCGGCGGGCTGGGGG
TGTCGCGTGGCCTGCAGGCGGTCGCCGACGGCATACTGCAGGGCGCCGGCGGACCGGTGCCTCTGGGGCTCAACCCGATG
GGTTACGGCATGGCGGCGCCGACCATCCGCGAGCACGCCCAGAACGACGACATCAAACGGGCCTGGTTGCGGCCGCTGGC
GACCACCGAACACATCTGGTGCCAGTTGTTCTCCGAACCCGGCGCCGGCTCCGATCTGGCCGGGCTGGCCACCTCGGCGG
TGCCCGACGGTGACGACTGGGTGATCAACGGCCAGAAGGTGTGGACCAGCCTCGCGCACCGCGCCCGGTGGGGTCTGCTG
CTGGCCCGCACGAACCCCGATGTGCCCAAGCACAAGGGTCTGACGTACTTCGTCATCGACATGCACGCACCGGGTGTCGA
GACCCGGCCGCTGCGGCAGATGACCGGCCACGCCGAGTTCAACGAGGTCTACTTCAGCGACGCCCGCATCCCCGACGCGC
ACCGGCTCGGCGGCGTCGGTGACGGCTGGCGGGTCGCGATGACGACGCTGATGAACGAGCGCAGCGCGCTGGGCGCCAGC
GGCAGCCGCCGCGGTGCGGGCACGATCGCCGACGCCGTCGCGCTGTGGGCGTCGCGCCCCGAGCGCCACACACCGGTGCT
GCGCGACCGGTTGTCCGAACTGTGGTTGCGCGCCGAGGCGCAACGGCTGACTTCCGAGCGGTCCCGAGCGTCGGCGACCG
TCGGCGGCCCGGGTCCGGAGGGATCGATCGGCAAGCTGGTCGGCGCCGAACTCAATCAGCGGATCTACCAGTGGTGCATG
GACTTTCTCGGCCCGGAGGGCACGCTGTACCACAGCTACGCCATGGACAGCGGGGACAAGAGCGACTGGCGCGGCCCGAT
TCAGCAGCGTTTCCTGCGCAGCCGCGCCAACACCATCGAGGGCGGCACCTCGGACGTCATGCGGAACATCCTGGGCGAGC
GGGTGCTCGGTCTGCCGGGTGATCTGCGTGCCGATGCGGGGATGCCGTGGAAGGAGGTGCCGCGTGGCTGA

Upstream 100 bases:

>100_bases
GGCCACAGAGGACCGAACTGTAACACGTTCCAGTTTCACCGCCAGCGCGTCTTCCGCCCTGCTCGTCACCCACGAGCATC
CTTTGCTTATGGTGGCTGAG

Downstream 100 bases:

>100_bases
GGCCTTCGTGTTCACCGAGGAGCAGCGGCAGCTGCGGGATGCGGTGCGGGGCTTCTGCTCCGACCACTTCGACGAGCAGA
CCGTGCGCCGGATCATGGAG

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MSTAADIDRVTELANRVVAEYDPKTVLIPEYLGACYDAGLSWVHFPEGLGGLGVSRGLQAVADGILQGAGGPVPLGLNPM
GYGMAAPTIREHAQNDDIKRAWLRPLATTEHIWCQLFSEPGAGSDLAGLATSAVPDGDDWVINGQKVWTSLAHRARWGLL
LARTNPDVPKHKGLTYFVIDMHAPGVETRPLRQMTGHAEFNEVYFSDARIPDAHRLGGVGDGWRVAMTTLMNERSALGAS
GSRRGAGTIADAVALWASRPERHTPVLRDRLSELWLRAEAQRLTSERSRASATVGGPGPEGSIGKLVGAELNQRIYQWCM
DFLGPEGTLYHSYAMDSGDKSDWRGPIQQRFLRSRANTIEGGTSDVMRNILGERVLGLPGDLRADAGMPWKEVPRG

Sequences:

>Translated_396_residues
MSTAADIDRVTELANRVVAEYDPKTVLIPEYLGACYDAGLSWVHFPEGLGGLGVSRGLQAVADGILQGAGGPVPLGLNPM
GYGMAAPTIREHAQNDDIKRAWLRPLATTEHIWCQLFSEPGAGSDLAGLATSAVPDGDDWVINGQKVWTSLAHRARWGLL
LARTNPDVPKHKGLTYFVIDMHAPGVETRPLRQMTGHAEFNEVYFSDARIPDAHRLGGVGDGWRVAMTTLMNERSALGAS
GSRRGAGTIADAVALWASRPERHTPVLRDRLSELWLRAEAQRLTSERSRASATVGGPGPEGSIGKLVGAELNQRIYQWCM
DFLGPEGTLYHSYAMDSGDKSDWRGPIQQRFLRSRANTIEGGTSDVMRNILGERVLGLPGDLRADAGMPWKEVPRG
>Mature_395_residues
STAADIDRVTELANRVVAEYDPKTVLIPEYLGACYDAGLSWVHFPEGLGGLGVSRGLQAVADGILQGAGGPVPLGLNPMG
YGMAAPTIREHAQNDDIKRAWLRPLATTEHIWCQLFSEPGAGSDLAGLATSAVPDGDDWVINGQKVWTSLAHRARWGLLL
ARTNPDVPKHKGLTYFVIDMHAPGVETRPLRQMTGHAEFNEVYFSDARIPDAHRLGGVGDGWRVAMTTLMNERSALGASG
SRRGAGTIADAVALWASRPERHTPVLRDRLSELWLRAEAQRLTSERSRASATVGGPGPEGSIGKLVGAELNQRIYQWCMD
FLGPEGTLYHSYAMDSGDKSDWRGPIQQRFLRSRANTIEGGTSDVMRNILGERVLGLPGDLRADAGMPWKEVPRG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI187960098, Length=372, Percent_Identity=27.4193548387097, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI4557231, Length=372, Percent_Identity=27.4193548387097, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI4557233, Length=349, Percent_Identity=27.2206303724928, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4501859, Length=295, Percent_Identity=25.7627118644068, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4501857, Length=362, Percent_Identity=25.414364640884, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI76496475, Length=286, Percent_Identity=26.9230769230769, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI4557235, Length=286, Percent_Identity=26.9230769230769, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI7656849, Length=365, Percent_Identity=24.1095890410959, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI21361497, Length=269, Percent_Identity=27.5092936802974, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI226958414, Length=146, Percent_Identity=32.1917808219178, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI226958412, Length=146, Percent_Identity=32.1917808219178, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI87081958, Length=261, Percent_Identity=25.2873563218391, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17570075, Length=377, Percent_Identity=27.5862068965517, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17534899, Length=370, Percent_Identity=25.9459459459459, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17569725, Length=370, Percent_Identity=24.5945945945946, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17508101, Length=368, Percent_Identity=25, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17505929, Length=218, Percent_Identity=27.9816513761468, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17538396, Length=346, Percent_Identity=25.1445086705202, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17551932, Length=206, Percent_Identity=27.1844660194175, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17506239, Length=329, Percent_Identity=23.7082066869301, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71990804, Length=269, Percent_Identity=24.1635687732342, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32563615, Length=124, Percent_Identity=33.0645161290323, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71982178, Length=261, Percent_Identity=24.5210727969349, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21356377, Length=352, Percent_Identity=27.2727272727273, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24660351, Length=366, Percent_Identity=26.2295081967213, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24646207, Length=352, Percent_Identity=26.9886363636364, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24666513, Length=316, Percent_Identity=25, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281363737, Length=362, Percent_Identity=25.414364640884, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI21355753, Length=286, Percent_Identity=24.1258741258741, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 42934; Mature: 42803

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAADIDRVTELANRVVAEYDPKTVLIPEYLGACYDAGLSWVHFPEGLGGLGVSRGLQA
CCCHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHH
VADGILQGAGGPVPLGLNPMGYGMAAPTIREHAQNDDIKRAWLRPLATTEHIWCQLFSEP
HHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCC
GAGSDLAGLATSAVPDGDDWVINGQKVWTSLAHRARWGLLLARTNPDVPKHKGLTYFVID
CCCCCHHHHHHCCCCCCCCEEECHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCEEEEEE
MHAPGVETRPLRQMTGHAEFNEVYFSDARIPDAHRLGGVGDGWRVAMTTLMNERSALGAS
ECCCCCCCCHHHHHHCCCCHHHEEECCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCC
GSRRGAGTIADAVALWASRPERHTPVLRDRLSELWLRAEAQRLTSERSRASATVGGPGPE
CCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GSIGKLVGAELNQRIYQWCMDFLGPEGTLYHSYAMDSGDKSDWRGPIQQRFLRSRANTIE
CCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCC
GGTSDVMRNILGERVLGLPGDLRADAGMPWKEVPRG
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCC
>Mature Secondary Structure 
STAADIDRVTELANRVVAEYDPKTVLIPEYLGACYDAGLSWVHFPEGLGGLGVSRGLQA
CCHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHH
VADGILQGAGGPVPLGLNPMGYGMAAPTIREHAQNDDIKRAWLRPLATTEHIWCQLFSEP
HHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCC
GAGSDLAGLATSAVPDGDDWVINGQKVWTSLAHRARWGLLLARTNPDVPKHKGLTYFVID
CCCCCHHHHHHCCCCCCCCEEECHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCEEEEEE
MHAPGVETRPLRQMTGHAEFNEVYFSDARIPDAHRLGGVGDGWRVAMTTLMNERSALGAS
ECCCCCCCCHHHHHHCCCCHHHEEECCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCC
GSRRGAGTIADAVALWASRPERHTPVLRDRLSELWLRAEAQRLTSERSRASATVGGPGPE
CCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GSIGKLVGAELNQRIYQWCMDFLGPEGTLYHSYAMDSGDKSDWRGPIQQRFLRSRANTIE
CCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCC
GGTSDVMRNILGERVLGLPGDLRADAGMPWKEVPRG
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]