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The map label for this gene is yprA [H]

Identifier: 119870913

GI number: 119870913

Start: 5120534

End: 5122861

Strand: Direct

Name: yprA [H]

Synonym: Mkms_4885

Alternate gene names: 119870913

Gene position: 5120534-5122861 (Clockwise)

Preceding gene: 119870909

Following gene: 119870914

Centisome position: 89.25

GC content: 71.05

Gene sequence:

>2328_bases
GTGTCAGATTTCGGCCGGGAGCTGCTGTCTTGTGCGGTGGCGGGGGTGGTGGCCGACGAGCATCCGCTGCGTCACGTCGC
CGACCTCCCGGCGCGGCCGGGGCAACCGGAATCGTGGCCGCAGTGGGCCCACCCAGATGTGGTGCGGGCGTTCGTTGATC
GGGGCGTGCGCACGCCGTGGTCCCATCAGCGCGCGGCGGCCGACCTCGCCCACGACGGCAGGCACGTGGTGCTGTCCACC
GGGACGGCGTCGGGTAAGTCACTGGCCTACCAACTGCCGATCCTGTCGGCGATGGCGTCCGAGCCCCGTACGCGCGCACT
GTATCTGTCCCCGACGAAGGCGTTGGGCCACGATCAGCTGCGTACCGCCCAGGCCCTCACCGACGCCGTCCCCGCCCTGC
ACGACGTGGCGCCGTCGTCGTACGACGGTGACAGCCCCGTCGACGTCCGGCGGTTCGCCAGGGAGCGGTCACGCTGGATC
TTCTCCAACCCGGACATGATCCACCTGTCGCTGCTGCGCAACCACGCCCGCTGGGCGGTGTTCCTGCGCCACCTCAAGTT
CATCGTGGTCGACGAATGCCACTACTACCGAGGCATATTCGGCTCCAACGTGGCGCTGGTGCTGCGCCGGCTGCTGCGGC
TGTGCGCCCGCTACTCCGCCGATCCGGGCGGCCCCACGGTCGTCTTCGCCAGCGCGACCACCGCCGCACCCTCCGCCACC
GCCGCCGAGCTGATCGGCCAGACGGTCACCGAGGTCACCGAGGACGGCTCCCCGCAGGGCGCGCGCACGGTGGCTTTGTG
GGAGCCGGCGTTGCTCACCGATCTGGTCGGCGAGAACGGCGCTCCGGTACGACGATCCGCGGGTGCGGAGGCCGCGCGGG
TGATGGCCGATCTGATCGCCGAGGGGGCGAGGACGCTGACGTTCGTCCGGTCCCGCCGCGGGGCCGAACTCACTGCGCTC
GGTGCGCGGGCCCGCCTCGAGGAGGTCGCCCCTGAACTGGTCGAGCAGGTGGCGTCCTACCGCGCGGGTTACCTCGCCGA
GGACCGCCGGGAGCTCGAACGCGCCCTCGCCGACGGGCGGCTTCGGGGTCTGGCCACCACCAACGCACTGGAACTCGGCG
TCGACATCGCGGGACTGGATGCGGTGGTGCTGGCCGGTTTCCCGGGTACGGTCACGTCGTTCTGGCAGCAGGCGGGGCGT
TCGGGCCGGCGCGGCCAGGGGGCGCTGATCGTGCTCGTCGCCCGCGACGACCCCCTCGACACCTATCTCGTGCACCATCC
GGAGGCCCTGCTGGACCGGCCGATCGAGCGCGTGGTGATCGATCCGGCGAACCCGTATGTGCTTGCACCGCAGTTGCTCT
GTGCGGCCACCGAGTTGCCGCTCACCGATTCCGAGGTGCGGATGTGGGACGCCGAGACGGTCGCGGAGTCACTCGTCGAC
GACGGTCTGCTGCGCCGCCGGGCGCACGGGTACTTCCCCGTACCCGGCCTCGATCCCCATCCCGCCGTGGACATCCGAGG
CTCCACCGGCGGGCAGATCGCGATCCTCGAGGCCGACACCGGTCGCATGCTCGGCAGCGCGAACGCCGGCCAGGCGGCGG
CATCGGTCCACCCGGGCGCGGTGTACCTGCACCAGGGAGAGAGCTACGTCGTGGACTCGCTGTCCTTCGAGGACGGCGTG
GCGTTCGTCCACGCGGAGGACCCCGGCTACACCACTTTCGCCAGGGAGGTCACCGAGATCGCGGTGACCGGCGCCGGGGA
GCGGGAGTCCTACGGCGCGGTGACCGTCGGCCTGGTTCCGGTGTCGGTGTCCAACACCGTGGTCGGCTATCTGCGCCGCC
GGCTCGACGGCGAGGTCATCGACTTCGTCGAACTCGACATGCCCACCCGGACACTGGACACCATGGCCGCGATGTGCACG
ATCACCCCGGAGGCGTTGCTGGACAACGGGATCGACCCGTTGCGGTTTCCCGGTTCACTGCACGCCGCCGAGCACGCGGC
GATCGGACTGCTGCCCCTGGTGGCCAGTTGCGACCGCGGCGACATCGGCGGGGTGTCGACCGCGGTGGGGCCGGAGGACG
GCCTGCCGACGATCTTCGTCTACGACGGCTATCCGGGCGGGGCGGGGTTCGCGGCCCGCGGATTCGGTCAGATCCGCACC
TGGTGGACGGCCACCGCCGACGCCATCGAGGCGTGTGAGTGCCCGGGCGGTTGCCCGTCCTGTGTGCAGTCACCCAAATG
CGGGAACGGCAACGATCCCCTCGACAAGGTGGGTGCGGTGCGGGTGCTGCGTCTGGTGCTGCGGGCGCTGGACGATCGTC
GCCGTTGA

Upstream 100 bases:

>100_bases
GTGCGACAGTCTCAGCGCCGTTCCTTGGGGAACAATTCACCTGTGCACCGACACCGACGGCGCGGCGCACCGTTACGGGC
ATGTTTCGGAAGGGCGGGCA

Downstream 100 bases:

>100_bases
CAGCGTTGACAGGAGGAACCGACCGACCCCTCGACGGTCGACTCCTCGTACGCAATCCGTTTTGCCACCCGGAACCGGGC
GTGGAAGCAAAATACCTTGT

Product: DEAD/DEAH box helicase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 775; Mature: 774

Protein sequence:

>775_residues
MSDFGRELLSCAVAGVVADEHPLRHVADLPARPGQPESWPQWAHPDVVRAFVDRGVRTPWSHQRAAADLAHDGRHVVLST
GTASGKSLAYQLPILSAMASEPRTRALYLSPTKALGHDQLRTAQALTDAVPALHDVAPSSYDGDSPVDVRRFARERSRWI
FSNPDMIHLSLLRNHARWAVFLRHLKFIVVDECHYYRGIFGSNVALVLRRLLRLCARYSADPGGPTVVFASATTAAPSAT
AAELIGQTVTEVTEDGSPQGARTVALWEPALLTDLVGENGAPVRRSAGAEAARVMADLIAEGARTLTFVRSRRGAELTAL
GARARLEEVAPELVEQVASYRAGYLAEDRRELERALADGRLRGLATTNALELGVDIAGLDAVVLAGFPGTVTSFWQQAGR
SGRRGQGALIVLVARDDPLDTYLVHHPEALLDRPIERVVIDPANPYVLAPQLLCAATELPLTDSEVRMWDAETVAESLVD
DGLLRRRAHGYFPVPGLDPHPAVDIRGSTGGQIAILEADTGRMLGSANAGQAAASVHPGAVYLHQGESYVVDSLSFEDGV
AFVHAEDPGYTTFAREVTEIAVTGAGERESYGAVTVGLVPVSVSNTVVGYLRRRLDGEVIDFVELDMPTRTLDTMAAMCT
ITPEALLDNGIDPLRFPGSLHAAEHAAIGLLPLVASCDRGDIGGVSTAVGPEDGLPTIFVYDGYPGGAGFAARGFGQIRT
WWTATADAIEACECPGGCPSCVQSPKCGNGNDPLDKVGAVRVLRLVLRALDDRRR

Sequences:

>Translated_775_residues
MSDFGRELLSCAVAGVVADEHPLRHVADLPARPGQPESWPQWAHPDVVRAFVDRGVRTPWSHQRAAADLAHDGRHVVLST
GTASGKSLAYQLPILSAMASEPRTRALYLSPTKALGHDQLRTAQALTDAVPALHDVAPSSYDGDSPVDVRRFARERSRWI
FSNPDMIHLSLLRNHARWAVFLRHLKFIVVDECHYYRGIFGSNVALVLRRLLRLCARYSADPGGPTVVFASATTAAPSAT
AAELIGQTVTEVTEDGSPQGARTVALWEPALLTDLVGENGAPVRRSAGAEAARVMADLIAEGARTLTFVRSRRGAELTAL
GARARLEEVAPELVEQVASYRAGYLAEDRRELERALADGRLRGLATTNALELGVDIAGLDAVVLAGFPGTVTSFWQQAGR
SGRRGQGALIVLVARDDPLDTYLVHHPEALLDRPIERVVIDPANPYVLAPQLLCAATELPLTDSEVRMWDAETVAESLVD
DGLLRRRAHGYFPVPGLDPHPAVDIRGSTGGQIAILEADTGRMLGSANAGQAAASVHPGAVYLHQGESYVVDSLSFEDGV
AFVHAEDPGYTTFAREVTEIAVTGAGERESYGAVTVGLVPVSVSNTVVGYLRRRLDGEVIDFVELDMPTRTLDTMAAMCT
ITPEALLDNGIDPLRFPGSLHAAEHAAIGLLPLVASCDRGDIGGVSTAVGPEDGLPTIFVYDGYPGGAGFAARGFGQIRT
WWTATADAIEACECPGGCPSCVQSPKCGNGNDPLDKVGAVRVLRLVLRALDDRRR
>Mature_774_residues
SDFGRELLSCAVAGVVADEHPLRHVADLPARPGQPESWPQWAHPDVVRAFVDRGVRTPWSHQRAAADLAHDGRHVVLSTG
TASGKSLAYQLPILSAMASEPRTRALYLSPTKALGHDQLRTAQALTDAVPALHDVAPSSYDGDSPVDVRRFARERSRWIF
SNPDMIHLSLLRNHARWAVFLRHLKFIVVDECHYYRGIFGSNVALVLRRLLRLCARYSADPGGPTVVFASATTAAPSATA
AELIGQTVTEVTEDGSPQGARTVALWEPALLTDLVGENGAPVRRSAGAEAARVMADLIAEGARTLTFVRSRRGAELTALG
ARARLEEVAPELVEQVASYRAGYLAEDRRELERALADGRLRGLATTNALELGVDIAGLDAVVLAGFPGTVTSFWQQAGRS
GRRGQGALIVLVARDDPLDTYLVHHPEALLDRPIERVVIDPANPYVLAPQLLCAATELPLTDSEVRMWDAETVAESLVDD
GLLRRRAHGYFPVPGLDPHPAVDIRGSTGGQIAILEADTGRMLGSANAGQAAASVHPGAVYLHQGESYVVDSLSFEDGVA
FVHAEDPGYTTFAREVTEIAVTGAGERESYGAVTVGLVPVSVSNTVVGYLRRRLDGEVIDFVELDMPTRTLDTMAAMCTI
TPEALLDNGIDPLRFPGSLHAAEHAAIGLLPLVASCDRGDIGGVSTAVGPEDGLPTIFVYDGYPGGAGFAARGFGQIRTW
WTATADAIEACECPGGCPSCVQSPKCGNGNDPLDKVGAVRVLRLVLRALDDRRR

Specific function: Unknown

COG id: COG1205

COG function: function code R; Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787942, Length=483, Percent_Identity=26.7080745341615, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320497, Length=777, Percent_Identity=33.0759330759331, Blast_Score=416, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR018973
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF09369 DUF1998; PF00271 Helicase_C [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 82833; Mature: 82702

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDFGRELLSCAVAGVVADEHPLRHVADLPARPGQPESWPQWAHPDVVRAFVDRGVRTPW
CCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
SHQRAAADLAHDGRHVVLSTGTASGKSLAYQLPILSAMASEPRTRALYLSPTKALGHDQL
CHHHHHHHHHCCCCEEEEEECCCCCCCEEEECHHHHHHHCCCCCEEEEECCHHHCCHHHH
RTAQALTDAVPALHDVAPSSYDGDSPVDVRRFARERSRWIFSNPDMIHLSLLRNHARWAV
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEECCCCEEEHHHHHHHHHHHH
FLRHLKFIVVDECHYYRGIFGSNVALVLRRLLRLCARYSADPGGPTVVFASATTAAPSAT
HHHHHHHEEEECHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHH
AAELIGQTVTEVTEDGSPQGARTVALWEPALLTDLVGENGAPVRRSAGAEAARVMADLIA
HHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
EGARTLTFVRSRRGAELTALGARARLEEVAPELVEQVASYRAGYLAEDRRELERALADGR
CCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
LRGLATTNALELGVDIAGLDAVVLAGFPGTVTSFWQQAGRSGRRGQGALIVLVARDDPLD
CCCEECCCHHHHCCEEECCCEEEEECCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCC
TYLVHHPEALLDRPIERVVIDPANPYVLAPQLLCAATELPLTDSEVRMWDAETVAESLVD
HHEEECCHHHHCCCCCEEEECCCCCEEECHHHHHHHCCCCCCCCHHEECCHHHHHHHHHH
DGLLRRRAHGYFPVPGLDPHPAVDIRGSTGGQIAILEADTGRMLGSANAGQAAASVHPGA
HHHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCCCCCCCCCCCCCCHHCCCCCE
VYLHQGESYVVDSLSFEDGVAFVHAEDPGYTTFAREVTEIAVTGAGERESYGAVTVGLVP
EEEECCCCEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHEEECCCCCCCCCEEEEEEEE
VSVSNTVVGYLRRRLDGEVIDFVELDMPTRTLDTMAAMCTITPEALLDNGIDPLRFPGSL
EEHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCC
HAAEHAAIGLLPLVASCDRGDIGGVSTAVGPEDGLPTIFVYDGYPGGAGFAARGFGQIRT
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHCCCCHHHH
WWTATADAIEACECPGGCPSCVQSPKCGNGNDPLDKVGAVRVLRLVLRALDDRRR
HHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDFGRELLSCAVAGVVADEHPLRHVADLPARPGQPESWPQWAHPDVVRAFVDRGVRTPW
CHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
SHQRAAADLAHDGRHVVLSTGTASGKSLAYQLPILSAMASEPRTRALYLSPTKALGHDQL
CHHHHHHHHHCCCCEEEEEECCCCCCCEEEECHHHHHHHCCCCCEEEEECCHHHCCHHHH
RTAQALTDAVPALHDVAPSSYDGDSPVDVRRFARERSRWIFSNPDMIHLSLLRNHARWAV
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEECCCCEEEHHHHHHHHHHHH
FLRHLKFIVVDECHYYRGIFGSNVALVLRRLLRLCARYSADPGGPTVVFASATTAAPSAT
HHHHHHHEEEECHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHH
AAELIGQTVTEVTEDGSPQGARTVALWEPALLTDLVGENGAPVRRSAGAEAARVMADLIA
HHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
EGARTLTFVRSRRGAELTALGARARLEEVAPELVEQVASYRAGYLAEDRRELERALADGR
CCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
LRGLATTNALELGVDIAGLDAVVLAGFPGTVTSFWQQAGRSGRRGQGALIVLVARDDPLD
CCCEECCCHHHHCCEEECCCEEEEECCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCC
TYLVHHPEALLDRPIERVVIDPANPYVLAPQLLCAATELPLTDSEVRMWDAETVAESLVD
HHEEECCHHHHCCCCCEEEECCCCCEEECHHHHHHHCCCCCCCCHHEECCHHHHHHHHHH
DGLLRRRAHGYFPVPGLDPHPAVDIRGSTGGQIAILEADTGRMLGSANAGQAAASVHPGA
HHHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCCCCCCCCCCCCCCHHCCCCCE
VYLHQGESYVVDSLSFEDGVAFVHAEDPGYTTFAREVTEIAVTGAGERESYGAVTVGLVP
EEEECCCCEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHEEECCCCCCCCCEEEEEEEE
VSVSNTVVGYLRRRLDGEVIDFVELDMPTRTLDTMAAMCTITPEALLDNGIDPLRFPGSL
EEHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCC
HAAEHAAIGLLPLVASCDRGDIGGVSTAVGPEDGLPTIFVYDGYPGGAGFAARGFGQIRT
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHCCCCHHHH
WWTATADAIEACECPGGCPSCVQSPKCGNGNDPLDKVGAVRVLRLVLRALDDRRR
HHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]