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The map label for this gene is 119870909

Identifier: 119870909

GI number: 119870909

Start: 5114734

End: 5116320

Strand: Direct

Name: 119870909

Synonym: Mkms_4881

Alternate gene names: NA

Gene position: 5114734-5116320 (Clockwise)

Preceding gene: 119870907

Following gene: 119870913

Centisome position: 89.15

GC content: 69.38

Gene sequence:

>1587_bases
GTGGCTTCGGAGGCGATACCGATCGGGCGAATCAGCGCATTCGTCCGGTGGGTCGCGCGCACGCCGTGGCCGGTCTTCAC
GCTGGGCATGTTGCAGGCCGACATCATCGGCGCATTGTTCGTGCTCGGCTTCCTGCGGTTCGGCCTGCCGCCCGAGGACC
GCGTCCAACTCCAGGACCTGCCCGCGTTCAACCTCGCGATCTTCCTGGGCTACCTGTTCGTCTCGTTCACCGTCGGCGCC
TATCTGAGCCTGCGGTTGCTCATCCCCGTCATCCGGTGGCAGCGGCGGGACACGCTGCTGGCCGACGGTGACACCAGCAC
GACCGACCTCGCCCGGGCGCGCGCCCTGCGTATGCCCTTCTATCGGACCGTCATCAGCGTCGCGAACTGGTGCCTGGGCT
CGATCGTGTTCATCGTCGCGAGTTGGCCGGTGGCCAGTAAGTCCGCGCCGGTCGTCGCCGTCGCCACCGCACTGGGCGCG
ACGGCCACCGCGATCATCGGCTACCTGCAGTCCGAGCGGGTCCTGCGACCGGTCGCCGTGGCCGCCCTGCGCGGCGGCGT
CCCGGAGAACTTCCGCGCCCCCGGCGTCGTTCTGCGCCAGGTTCTCACCTGGGTGTTGTCCACGGGTGTGCCGGTGCTGG
CCATCGTGCTCGCACTGGTGGCCAGCCAGTTCGACATCCTCGAGGCGCCCGCGGACCGGCTGACCATGCCGATTCTGCTG
CTGGCCATCGCCGCGCTGGTGATCGGGCTGGCCGGCACCGTCCTGGTGGCCATGTCGATCGCCGATCCGCTGCGCCAGTT
GCGCTGGGCGCTCGGTGAGGTGCAGCGCGGCAACTACAACGCCCACATGCAGATCTACGACGCCAGCGAGCTGGGCCTGC
TGCAGGCCGGGTTCAACGACATGGTCCGCGACCTGTCCGAACGGCAGCGGTTGCGCGACCTGTTCGGCCGTTACGTCGGC
GAGGACGTCGCGCGCCGGGCACTGGAACGCGGCACCGAACTCGGCGGCCAGGAGCGCGACGTGGCCGTCCTGTTCGTCGA
TCTGGTCGGTTCCACCCAGCTCGCCTCGACGATCCCGGCGGCCGACGTGGTCAACCTGCTCAACGACTTCTTCCGGGTGG
TCGTCGACACCGTCAACCGCCACGGCGGGTTCGTCAACAAGTTCCAGGGCGACGCGGCGCTGGCCATCTTCGGCGCCCCG
ATCGAGCATCCGGACGCGTGCGGTGCGGCGTTGGCGGCCTCTCGTGAACTGCACGACGAGCTCATCAAGGTCCTCGGCCA
GACCGAATTCGGCATCGGGGTGTCGGCGGGACGCGCGATCGCCGGCCACATCGGCGCCCAGGCCCGTTTCGAGTACACCG
TGATCGGCGACCCGGTCAACGAGGCCGCACGGCTGACCGAACTCGCCAAACTCGAACCCGGCCACGTCCTGGCGTCGGCG
ATCGCGGTCAGCGGCGCACTCGACGCCGAGGCGCTGTGCTGGAACGTCGGTGAGACAGTCGAACTGCGCGGCCGCATCGC
GCCGACCCAGTTGGCCCGCCCGGTGAACCTGATGTCGCCGCGCGAGATCAGCGATCTGTCGCGCTGA

Upstream 100 bases:

>100_bases
GGGAAAAAACTCCGGCCATCACCGCCAACAGTAGTGGTCAGACCGACACAACTGGCTGACAGCGGCGCTCAAGGTCACCT
TCGCCCGATACGGTAAACGG

Downstream 100 bases:

>100_bases
GAACTACGCCTTCTTGGCGGACGCCTTCTTCGCCGCGGTCTTCTTGGCCGCGGTCTTCTTCGCCGGCGCCTTCTTGGCCG
CGGCCTTCTTCTTGACCGGT

Product: putative adenylate/guanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 528; Mature: 527

Protein sequence:

>528_residues
MASEAIPIGRISAFVRWVARTPWPVFTLGMLQADIIGALFVLGFLRFGLPPEDRVQLQDLPAFNLAIFLGYLFVSFTVGA
YLSLRLLIPVIRWQRRDTLLADGDTSTTDLARARALRMPFYRTVISVANWCLGSIVFIVASWPVASKSAPVVAVATALGA
TATAIIGYLQSERVLRPVAVAALRGGVPENFRAPGVVLRQVLTWVLSTGVPVLAIVLALVASQFDILEAPADRLTMPILL
LAIAALVIGLAGTVLVAMSIADPLRQLRWALGEVQRGNYNAHMQIYDASELGLLQAGFNDMVRDLSERQRLRDLFGRYVG
EDVARRALERGTELGGQERDVAVLFVDLVGSTQLASTIPAADVVNLLNDFFRVVVDTVNRHGGFVNKFQGDAALAIFGAP
IEHPDACGAALAASRELHDELIKVLGQTEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEPGHVLASA
IAVSGALDAEALCWNVGETVELRGRIAPTQLARPVNLMSPREISDLSR

Sequences:

>Translated_528_residues
MASEAIPIGRISAFVRWVARTPWPVFTLGMLQADIIGALFVLGFLRFGLPPEDRVQLQDLPAFNLAIFLGYLFVSFTVGA
YLSLRLLIPVIRWQRRDTLLADGDTSTTDLARARALRMPFYRTVISVANWCLGSIVFIVASWPVASKSAPVVAVATALGA
TATAIIGYLQSERVLRPVAVAALRGGVPENFRAPGVVLRQVLTWVLSTGVPVLAIVLALVASQFDILEAPADRLTMPILL
LAIAALVIGLAGTVLVAMSIADPLRQLRWALGEVQRGNYNAHMQIYDASELGLLQAGFNDMVRDLSERQRLRDLFGRYVG
EDVARRALERGTELGGQERDVAVLFVDLVGSTQLASTIPAADVVNLLNDFFRVVVDTVNRHGGFVNKFQGDAALAIFGAP
IEHPDACGAALAASRELHDELIKVLGQTEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEPGHVLASA
IAVSGALDAEALCWNVGETVELRGRIAPTQLARPVNLMSPREISDLSR
>Mature_527_residues
ASEAIPIGRISAFVRWVARTPWPVFTLGMLQADIIGALFVLGFLRFGLPPEDRVQLQDLPAFNLAIFLGYLFVSFTVGAY
LSLRLLIPVIRWQRRDTLLADGDTSTTDLARARALRMPFYRTVISVANWCLGSIVFIVASWPVASKSAPVVAVATALGAT
ATAIIGYLQSERVLRPVAVAALRGGVPENFRAPGVVLRQVLTWVLSTGVPVLAIVLALVASQFDILEAPADRLTMPILLL
AIAALVIGLAGTVLVAMSIADPLRQLRWALGEVQRGNYNAHMQIYDASELGLLQAGFNDMVRDLSERQRLRDLFGRYVGE
DVARRALERGTELGGQERDVAVLFVDLVGSTQLASTIPAADVVNLLNDFFRVVVDTVNRHGGFVNKFQGDAALAIFGAPI
EHPDACGAALAASRELHDELIKVLGQTEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEPGHVLASAI
AVSGALDAEALCWNVGETVELRGRIAPTQLARPVNLMSPREISDLSR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI17534657, Length=222, Percent_Identity=27.027027027027, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00672 HAMP [H]

EC number: NA

Molecular weight: Translated: 56776; Mature: 56644

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS50885 HAMP ; PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASEAIPIGRISAFVRWVARTPWPVFTLGMLQADIIGALFVLGFLRFGLPPEDRVQLQDL
CCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCC
PAFNLAIFLGYLFVSFTVGAYLSLRLLIPVIRWQRRDTLLADGDTSTTDLARARALRMPF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHCHH
YRTVISVANWCLGSIVFIVASWPVASKSAPVVAVATALGATATAIIGYLQSERVLRPVAV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALRGGVPENFRAPGVVLRQVLTWVLSTGVPVLAIVLALVASQFDILEAPADRLTMPILL
HHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LAIAALVIGLAGTVLVAMSIADPLRQLRWALGEVQRGNYNAHMQIYDASELGLLQAGFND
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHCHHH
MVRDLSERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLASTIPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHCCHHHHHHCCH
ADVVNLLNDFFRVVVDTVNRHGGFVNKFQGDAALAIFGAPIEHPDACGAALAASRELHDE
HHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHH
LIKVLGQTEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEPGHVLASA
HHHHHCCCCCCCCCCCCCHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHH
IAVSGALDAEALCWNVGETVELRGRIAPTQLARPVNLMSPREISDLSR
HHHHCCCCHHHHHHCCCCCEEECCCCCHHHHCCCCCCCCCCCHHHCCC
>Mature Secondary Structure 
ASEAIPIGRISAFVRWVARTPWPVFTLGMLQADIIGALFVLGFLRFGLPPEDRVQLQDL
CCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCC
PAFNLAIFLGYLFVSFTVGAYLSLRLLIPVIRWQRRDTLLADGDTSTTDLARARALRMPF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHCHH
YRTVISVANWCLGSIVFIVASWPVASKSAPVVAVATALGATATAIIGYLQSERVLRPVAV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALRGGVPENFRAPGVVLRQVLTWVLSTGVPVLAIVLALVASQFDILEAPADRLTMPILL
HHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LAIAALVIGLAGTVLVAMSIADPLRQLRWALGEVQRGNYNAHMQIYDASELGLLQAGFND
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHCHHH
MVRDLSERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLASTIPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHCCHHHHHHCCH
ADVVNLLNDFFRVVVDTVNRHGGFVNKFQGDAALAIFGAPIEHPDACGAALAASRELHDE
HHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHH
LIKVLGQTEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEPGHVLASA
HHHHHCCCCCCCCCCCCCHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHH
IAVSGALDAEALCWNVGETVELRGRIAPTQLARPVNLMSPREISDLSR
HHHHCCCCHHHHHHCCCCCEEECCCCCHHHHCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]