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The map label for this gene is yjjN [C]

Identifier: 119870887

GI number: 119870887

Start: 5087746

End: 5088762

Strand: Direct

Name: yjjN [C]

Synonym: Mkms_4859

Alternate gene names: 119870887

Gene position: 5087746-5088762 (Clockwise)

Preceding gene: 119870886

Following gene: 119870888

Centisome position: 88.68

GC content: 70.6

Gene sequence:

>1017_bases
GTGCGCGCGTCGGTGCTGCGCGGCGGCCGCATGGTGTTGCGTGACGATGTGCCCGAACCGGTTCCCGGGCCGGGGCAGGT
GCTGGTCGCGGTGAAGGCGTGCGGCATCTGCGGATCCGATCTGCACTTCGCCGCCCACGGCGACGACGCGCTGGCCGCGG
GTGCGCAGATGGAGGGCATGCCCCAGCTGGGCGACACCGTCGACCTGTCCGCCGACGTGTTCATGGGCCACGAGATCGCC
GCGGAGGTGCTCGAAGCCGGTCCGGACACCGACGCTCCGCCACCGGGTACCGTCGTGACGTCGATCCCGGCGCTGATCTC
GCAGACCGGTGTCGCTCCGATCGTGTACTCCAACAGCGTCATCGGCGGATACGCCGAACGCATGCTGCTGTCGGCGCCGC
TCCTGCTGCCCGTGCCGAACGGGCTCGATCCCCGGCACGCCGCGCTGACCGAGCCGATGGCGGTGGGCCTGCACGCGGTG
AACAGGTCCGCGATCACCCCTGCCGAATCCGCGCTCGTGATCGGATGCGGGCCGATCGGCATGGCAATCATCGCCGCGCT
GCGGTTGCGCGGCGTCGAACATGTTGTCGCAGCGGACTTCTCGCAGACCCGACGCCGGCTTGCGCAGACCATGGGCGCGC
ACGAGACCGTCGACCCGGCGCAGCGGTCCCCGTTCGAGGTCGCCGCGCCCGCGGTGGTGTTCGAGGCCGTCGGCGCCCCG
GGCATCCTCAACGACGTCATGCGCCGCGCACCGGCCCACACCCGCGTGGTGGTGGCCGGGGTGTGCATGGAACCCGACAC
CGTGATGCCGTTCTACGGCGCCCCGAAGGAACTCAGCATCCAGTTTGTGTTCGCCTATGACGTGGGCGAGTTCGCGGAGA
CGTTGCGGGCCATCGCCGAAGGCGCGATCGACGTCGCACCGCTGATCACCGGGGAGGTCGGTCTCGACGGGGTGGGCGAC
GCCTTCGCCACGCTGTCGCGCCCCGCCGAGCAATGCAAGATCTTGGTCACGCCCTGA

Upstream 100 bases:

>100_bases
GGGCCAAGGGTATGCGCGACCAGTTGCTCGGCCGGGCCGGCGACGCGATCGTCAAGGCGATCACCGAACACACCGACGAG
TTGAAGGTGGACCCGCGGTA

Downstream 100 bases:

>100_bases
CGGTAGGGTGCCTGACATGCCGATCTCTGCGCGCGCGAAGACCCGGTTGCTCACCTTCGTCGCGGCGGGTGTGACGGTGG
CCGGGGTGGCCGGGTGTGAC

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: Xylitol dehydrogenase; XDH [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MRASVLRGGRMVLRDDVPEPVPGPGQVLVAVKACGICGSDLHFAAHGDDALAAGAQMEGMPQLGDTVDLSADVFMGHEIA
AEVLEAGPDTDAPPPGTVVTSIPALISQTGVAPIVYSNSVIGGYAERMLLSAPLLLPVPNGLDPRHAALTEPMAVGLHAV
NRSAITPAESALVIGCGPIGMAIIAALRLRGVEHVVAADFSQTRRRLAQTMGAHETVDPAQRSPFEVAAPAVVFEAVGAP
GILNDVMRRAPAHTRVVVAGVCMEPDTVMPFYGAPKELSIQFVFAYDVGEFAETLRAIAEGAIDVAPLITGEVGLDGVGD
AFATLSRPAEQCKILVTP

Sequences:

>Translated_338_residues
MRASVLRGGRMVLRDDVPEPVPGPGQVLVAVKACGICGSDLHFAAHGDDALAAGAQMEGMPQLGDTVDLSADVFMGHEIA
AEVLEAGPDTDAPPPGTVVTSIPALISQTGVAPIVYSNSVIGGYAERMLLSAPLLLPVPNGLDPRHAALTEPMAVGLHAV
NRSAITPAESALVIGCGPIGMAIIAALRLRGVEHVVAADFSQTRRRLAQTMGAHETVDPAQRSPFEVAAPAVVFEAVGAP
GILNDVMRRAPAHTRVVVAGVCMEPDTVMPFYGAPKELSIQFVFAYDVGEFAETLRAIAEGAIDVAPLITGEVGLDGVGD
AFATLSRPAEQCKILVTP
>Mature_338_residues
MRASVLRGGRMVLRDDVPEPVPGPGQVLVAVKACGICGSDLHFAAHGDDALAAGAQMEGMPQLGDTVDLSADVFMGHEIA
AEVLEAGPDTDAPPPGTVVTSIPALISQTGVAPIVYSNSVIGGYAERMLLSAPLLLPVPNGLDPRHAALTEPMAVGLHAV
NRSAITPAESALVIGCGPIGMAIIAALRLRGVEHVVAADFSQTRRRLAQTMGAHETVDPAQRSPFEVAAPAVVFEAVGAP
GILNDVMRRAPAHTRVVVAGVCMEPDTVMPFYGAPKELSIQFVFAYDVGEFAETLRAIAEGAIDVAPLITGEVGLDGVGD
AFATLSRPAEQCKILVTP

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=334, Percent_Identity=25.748502994012, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI226510992, Length=331, Percent_Identity=29.3051359516616, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1787863, Length=327, Percent_Identity=25.9938837920489, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1788073, Length=323, Percent_Identity=24.1486068111455, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790718, Length=310, Percent_Identity=25.4838709677419, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788075, Length=347, Percent_Identity=23.9193083573487, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788407, Length=349, Percent_Identity=22.0630372492837, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17562876, Length=356, Percent_Identity=25, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17562878, Length=242, Percent_Identity=27.2727272727273, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319258, Length=396, Percent_Identity=27.2727272727273, Blast_Score=106, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6319257, Length=386, Percent_Identity=27.720207253886, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6319955, Length=327, Percent_Identity=23.8532110091743, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322619, Length=334, Percent_Identity=23.6526946107784, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323099, Length=355, Percent_Identity=23.6619718309859, Blast_Score=83, Evalue=5e-17,
Organism=Drosophila melanogaster, GI17737897, Length=349, Percent_Identity=24.9283667621776, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI17137530, Length=343, Percent_Identity=26.2390670553936, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.9 [H]

Molecular weight: Translated: 34895; Mature: 34895

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRASVLRGGRMVLRDDVPEPVPGPGQVLVAVKACGICGSDLHFAAHGDDALAAGAQMEGM
CCCCCCCCCCEEEECCCCCCCCCCCCEEEEEECCCCCCCCCEEEECCCHHHHCCCCCCCC
PQLGDTVDLSADVFMGHEIAAEVLEAGPDTDAPPPGTVVTSIPALISQTGVAPIVYSNSV
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCC
IGGYAERMLLSAPLLLPVPNGLDPRHAALTEPMAVGLHAVNRSAITPAESALVIGCGPIG
HHHHHHHHHHHCCCEEECCCCCCCCHHHHCCHHHHHHHHHCCCCCCCCCCEEEEECCHHH
MAIIAALRLRGVEHVVAADFSQTRRRLAQTMGAHETVDPAQRSPFEVAAPAVVFEAVGAP
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
GILNDVMRRAPAHTRVVVAGVCMEPDTVMPFYGAPKELSIQFVFAYDVGEFAETLRAIAE
HHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCCEEEEEEEEECHHHHHHHHHHHHH
GAIDVAPLITGEVGLDGVGDAFATLSRPAEQCKILVTP
CCCEEHHEEECCCCCCCCCHHHHHHCCCHHHCEEEECC
>Mature Secondary Structure
MRASVLRGGRMVLRDDVPEPVPGPGQVLVAVKACGICGSDLHFAAHGDDALAAGAQMEGM
CCCCCCCCCCEEEECCCCCCCCCCCCEEEEEECCCCCCCCCEEEECCCHHHHCCCCCCCC
PQLGDTVDLSADVFMGHEIAAEVLEAGPDTDAPPPGTVVTSIPALISQTGVAPIVYSNSV
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCC
IGGYAERMLLSAPLLLPVPNGLDPRHAALTEPMAVGLHAVNRSAITPAESALVIGCGPIG
HHHHHHHHHHHCCCEEECCCCCCCCHHHHCCHHHHHHHHHCCCCCCCCCCEEEEECCHHH
MAIIAALRLRGVEHVVAADFSQTRRRLAQTMGAHETVDPAQRSPFEVAAPAVVFEAVGAP
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
GILNDVMRRAPAHTRVVVAGVCMEPDTVMPFYGAPKELSIQFVFAYDVGEFAETLRAIAE
HHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCCEEEEEEEEECHHHHHHHHHHHHH
GAIDVAPLITGEVGLDGVGDAFATLSRPAEQCKILVTP
CCCEEHHEEECCCCCCCCCHHHHHHCCCHHHCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]