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The map label for this gene is yfhM [H]

Identifier: 119870885

GI number: 119870885

Start: 5085612

End: 5086559

Strand: Direct

Name: yfhM [H]

Synonym: Mkms_4857

Alternate gene names: 119870885

Gene position: 5085612-5086559 (Clockwise)

Preceding gene: 119870873

Following gene: 119870886

Centisome position: 88.64

GC content: 70.04

Gene sequence:

>948_bases
GTGTGCTTGGGTGAGACCGTGATCACCCCGACCGAACGGTTAGTCGGCACCAACGGCGTACGTCTGCGCGTCGTGGAGGC
CGGTGAGCGCGGAGCGCCCGTCGTCGTGCTCGCCCACGGCTTCCCGGAACTGGCCTACTCGTGGCGGCATCAGATCCCGG
TGCTCGCCGAGGCCGGTTACCACGTCATCGCCCCGGATCAGCGCGGCTACGGCGGGTCGACCCGCCCCGACGCCGTCGAG
GACTACGACATCGTCGCGCTGACCGGCGACCTCGCCGGCCTGCTCGACGACGTCGGCGCACAGCGCGCGGTGGTGGTCGG
ACACGACTGGGGCTCCCCGGTCGTCACCAACTTCGCGCTGCTGTACCCCGACCGGGTGGCGGGGATGGTCAACCTGAGCG
TGCCGCCGGTGCCCCGGGCCTCCGACCCGCCGACCCAGATCTGGCGCAAGACCTTCGGCGACCACTTCTTCTACATCCTC
TACTTCCAGGAACCCGGCGTCGCCGACGCCGACCTCGGCCGCGACCCCCGGCAGTCCCTGCAGCGCATGTTGGCGCTCGA
GGGGTTCAGCGCCCCGGCGCCCGACCTGGCCGACAATCCGCTGCCGCCGCTGCCGGAGTGGATGAGCCAGGAGGAGTTCG
ACCACTACGCCGACGTCTTCACCCGCACCGGCTTCACCGGCGGGCTGAACTGGTACCGCAACTTCGACCGGAACTGGGAG
CTGACCGCCACCACACCCGCCGCCACCATCACGGTGCCGACGCTGTTCATCGCCGGCAGCGCCGACCCGGTGCTGAGCTT
CACCCCACGCCACCGGGTGACCGACCTGGTCACCGGCGAGTACCGCGAGGTGCTGCTCGACGGTGCAGGCCACTGGCTCC
AGCAGGAACGGCCCGACGAGGTCAACGCACTGTTGCTGGAGCATCTGGCCGGATTGGAGCTGACATGA

Upstream 100 bases:

>100_bases
TCCTCCCGTACCGCCTACCGGCGTGGCCGTCGTGCCCGGCGAACCGGCCGCCACAGAACTGGACACGGCCGTCTCCAAAC
GACTTCCGCAGCGGGGACCC

Downstream 100 bases:

>100_bases
GCCGCAAACCGCTGAACTTCGGCGTCTTCATCACACCGTTCCACCCGGTGGGCCAATCCCCCACCGTCGCATTGGAATAC
GACCTCGAGCGGGTGGTGCG

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MCLGETVITPTERLVGTNGVRLRVVEAGERGAPVVVLAHGFPELAYSWRHQIPVLAEAGYHVIAPDQRGYGGSTRPDAVE
DYDIVALTGDLAGLLDDVGAQRAVVVGHDWGSPVVTNFALLYPDRVAGMVNLSVPPVPRASDPPTQIWRKTFGDHFFYIL
YFQEPGVADADLGRDPRQSLQRMLALEGFSAPAPDLADNPLPPLPEWMSQEEFDHYADVFTRTGFTGGLNWYRNFDRNWE
LTATTPAATITVPTLFIAGSADPVLSFTPRHRVTDLVTGEYREVLLDGAGHWLQQERPDEVNALLLEHLAGLELT

Sequences:

>Translated_315_residues
MCLGETVITPTERLVGTNGVRLRVVEAGERGAPVVVLAHGFPELAYSWRHQIPVLAEAGYHVIAPDQRGYGGSTRPDAVE
DYDIVALTGDLAGLLDDVGAQRAVVVGHDWGSPVVTNFALLYPDRVAGMVNLSVPPVPRASDPPTQIWRKTFGDHFFYIL
YFQEPGVADADLGRDPRQSLQRMLALEGFSAPAPDLADNPLPPLPEWMSQEEFDHYADVFTRTGFTGGLNWYRNFDRNWE
LTATTPAATITVPTLFIAGSADPVLSFTPRHRVTDLVTGEYREVLLDGAGHWLQQERPDEVNALLLEHLAGLELT
>Mature_315_residues
MCLGETVITPTERLVGTNGVRLRVVEAGERGAPVVVLAHGFPELAYSWRHQIPVLAEAGYHVIAPDQRGYGGSTRPDAVE
DYDIVALTGDLAGLLDDVGAQRAVVVGHDWGSPVVTNFALLYPDRVAGMVNLSVPPVPRASDPPTQIWRKTFGDHFFYIL
YFQEPGVADADLGRDPRQSLQRMLALEGFSAPAPDLADNPLPPLPEWMSQEEFDHYADVFTRTGFTGGLNWYRNFDRNWE
LTATTPAATITVPTLFIAGSADPVLSFTPRHRVTDLVTGEYREVLLDGAGHWLQQERPDEVNALLLEHLAGLELT

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=300, Percent_Identity=37.3333333333333, Blast_Score=201, Evalue=7e-52,
Organism=Homo sapiens, GI218777837, Length=298, Percent_Identity=28.5234899328859, Blast_Score=138, Evalue=6e-33,
Organism=Homo sapiens, GI218777840, Length=300, Percent_Identity=29.3333333333333, Blast_Score=131, Evalue=6e-31,
Organism=Homo sapiens, GI13376164, Length=300, Percent_Identity=29.3333333333333, Blast_Score=131, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17554012, Length=308, Percent_Identity=29.5454545454545, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17562298, Length=302, Percent_Identity=24.8344370860927, Blast_Score=104, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6324392, Length=126, Percent_Identity=32.5396825396825, Blast_Score=76, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 34621; Mature: 34621

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS00888 CNMP_BINDING_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCLGETVITPTERLVGTNGVRLRVVEAGERGAPVVVLAHGFPELAYSWRHQIPVLAEAGY
CCCCCCCCCCHHHHHCCCCCEEEEEECCCCCCCEEEEECCCHHHHHHHHCCCCEEECCCE
HVIAPDQRGYGGSTRPDAVEDYDIVALTGDLAGLLDDVGAQRAVVVGHDWGSPVVTNFAL
EEECCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHCCCCEEEEEECCCCCHHHHHEEE
LYPDRVAGMVNLSVPPVPRASDPPTQIWRKTFGDHFFYILYFQEPGVADADLGRDPRQSL
ECCHHHCEEEEECCCCCCCCCCCHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCHHHHH
QRMLALEGFSAPAPDLADNPLPPLPEWMSQEEFDHYADVFTRTGFTGGLNWYRNFDRNWE
HHHHHHCCCCCCCCCCCCCCCCCCHHHHCHHHHHHHHHHHHHCCCCCCCHHHHCCCCCEE
LTATTPAATITVPTLFIAGSADPVLSFTPRHRVTDLVTGEYREVLLDGAGHWLQQERPDE
EEEECCCEEEEEEEEEEECCCCCCEEECCCHHHHHHHCCHHHHHHHHCCCHHHHCCCCHH
VNALLLEHLAGLELT
HHHHHHHHHCCCCCC
>Mature Secondary Structure
MCLGETVITPTERLVGTNGVRLRVVEAGERGAPVVVLAHGFPELAYSWRHQIPVLAEAGY
CCCCCCCCCCHHHHHCCCCCEEEEEECCCCCCCEEEEECCCHHHHHHHHCCCCEEECCCE
HVIAPDQRGYGGSTRPDAVEDYDIVALTGDLAGLLDDVGAQRAVVVGHDWGSPVVTNFAL
EEECCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHCCCCEEEEEECCCCCHHHHHEEE
LYPDRVAGMVNLSVPPVPRASDPPTQIWRKTFGDHFFYILYFQEPGVADADLGRDPRQSL
ECCHHHCEEEEECCCCCCCCCCCHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCHHHHH
QRMLALEGFSAPAPDLADNPLPPLPEWMSQEEFDHYADVFTRTGFTGGLNWYRNFDRNWE
HHHHHHCCCCCCCCCCCCCCCCCCHHHHCHHHHHHHHHHHHHCCCCCCCHHHHCCCCCEE
LTATTPAATITVPTLFIAGSADPVLSFTPRHRVTDLVTGEYREVLLDGAGHWLQQERPDE
EEEECCCEEEEEEEEEEECCCCCCEEECCCHHHHHHHCCHHHHHHHHCCCHHHHCCCCHH
VNALLLEHLAGLELT
HHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]