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The map label for this gene is coxS [H]

Identifier: 119870720

GI number: 119870720

Start: 4916432

End: 4916926

Strand: Direct

Name: coxS [H]

Synonym: Mkms_4691

Alternate gene names: 119870720

Gene position: 4916432-4916926 (Clockwise)

Preceding gene: 119870719

Following gene: 119870721

Centisome position: 85.69

GC content: 67.68

Gene sequence:

>495_bases
ATGCATGAGTTGCCGGTCGAGTTGACGGTCAACGGCCGCAACCATCGCGGAGTGGTGGAGCCGCGTATCACGTTGGCCGA
CTTCCTGCGCGAGACATGCGGTCTCACCGGCACGCACCTAGGCTGCGAGCACGGGGCGTGCGGTGCGTGCACGGTGCTGC
TCGACGGGCAGGCGGTCCGGTCCTGTCTGGTGTTCGCGGTGCAGGCCGACGGCCAGGAGGTCACCACCGTCGAAGGCATC
GCCGGACCCGACGGTGAGCTCTCCCCCGTGCAGGCCGCGATGAAGGAATGCCACGGACTCCAATGCGGTTTCTGCACACC
GGGCTTCGTCACCTCGATCACGGCGCTGCTGGCCGACAACCCGGATCCGAGCGACGAGGAGATCCGCGAAGGGTTGTCGG
GCAACTTCTGCCGATGCACGGGATACCAGGGCATCGTCAACGCCGTCCGCCTCGCCGCCGAGCGCACGCGCAACGGGCAG
ACCGTAAGCCCGTAG

Upstream 100 bases:

>100_bases
CTTCAAGGTTCGGCGAGCTATCGGCGCCGGGTCGGCGCCGCGATGGTCTCGCGTGCCCTGGCATCGGCGGTCGCCCAGGT
GACTTCGGAGGAGATGATCC

Downstream 100 bases:

>100_bases
GCGAGGCGACCACGGCAGGTGTTTGCCGGTGCAGCGGCAATAATCCCGCGATCCCGGGCGTTGGCGCGAAGATGAGCAAC
ATGCACATCGGTTTCATCGG

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MHELPVELTVNGRNHRGVVEPRITLADFLRETCGLTGTHLGCEHGACGACTVLLDGQAVRSCLVFAVQADGQEVTTVEGI
AGPDGELSPVQAAMKECHGLQCGFCTPGFVTSITALLADNPDPSDEEIREGLSGNFCRCTGYQGIVNAVRLAAERTRNGQ
TVSP

Sequences:

>Translated_164_residues
MHELPVELTVNGRNHRGVVEPRITLADFLRETCGLTGTHLGCEHGACGACTVLLDGQAVRSCLVFAVQADGQEVTTVEGI
AGPDGELSPVQAAMKECHGLQCGFCTPGFVTSITALLADNPDPSDEEIREGLSGNFCRCTGYQGIVNAVRLAAERTRNGQ
TVSP
>Mature_164_residues
MHELPVELTVNGRNHRGVVEPRITLADFLRETCGLTGTHLGCEHGACGACTVLLDGQAVRSCLVFAVQADGQEVTTVEGI
AGPDGELSPVQAAMKECHGLQCGFCTPGFVTSITALLADNPDPSDEEIREGLSGNFCRCTGYQGIVNAVRLAAERTRNGQ
TVSP

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=154, Percent_Identity=44.1558441558442, Blast_Score=102, Evalue=1e-22,
Organism=Homo sapiens, GI71773480, Length=90, Percent_Identity=46.6666666666667, Blast_Score=98, Evalue=3e-21,
Organism=Escherichia coli, GI1786480, Length=165, Percent_Identity=43.030303030303, Blast_Score=133, Evalue=7e-33,
Organism=Escherichia coli, GI1789232, Length=156, Percent_Identity=47.4358974358974, Blast_Score=126, Evalue=6e-31,
Organism=Escherichia coli, GI1789246, Length=116, Percent_Identity=34.4827586206897, Blast_Score=67, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17540638, Length=149, Percent_Identity=46.9798657718121, Blast_Score=136, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17539860, Length=153, Percent_Identity=43.1372549019608, Blast_Score=128, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI32566215, Length=153, Percent_Identity=43.7908496732026, Blast_Score=127, Evalue=4e-30,
Organism=Drosophila melanogaster, GI17737937, Length=152, Percent_Identity=44.7368421052632, Blast_Score=114, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24647199, Length=135, Percent_Identity=39.2592592592593, Blast_Score=103, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24647193, Length=157, Percent_Identity=35.6687898089172, Blast_Score=96, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24647201, Length=155, Percent_Identity=34.8387096774194, Blast_Score=96, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24647195, Length=161, Percent_Identity=31.6770186335404, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24647197, Length=161, Percent_Identity=31.6770186335404, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 17254; Mature: 17254

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
6.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHELPVELTVNGRNHRGVVEPRITLADFLRETCGLTGTHLGCEHGACGACTVLLDGQAVR
CCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCHHHH
SCLVFAVQADGQEVTTVEGIAGPDGELSPVQAAMKECHGLQCGFCTPGFVTSITALLADN
HHHHEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCC
PDPSDEEIREGLSGNFCRCTGYQGIVNAVRLAAERTRNGQTVSP
CCCCHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MHELPVELTVNGRNHRGVVEPRITLADFLRETCGLTGTHLGCEHGACGACTVLLDGQAVR
CCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCHHHH
SCLVFAVQADGQEVTTVEGIAGPDGELSPVQAAMKECHGLQCGFCTPGFVTSITALLADN
HHHHEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCC
PDPSDEEIREGLSGNFCRCTGYQGIVNAVRLAAERTRNGQTVSP
CCCCHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 10430865; 12475995 [H]