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The map label for this gene is cutL [H]

Identifier: 119870717

GI number: 119870717

Start: 4912500

End: 4914827

Strand: Direct

Name: cutL [H]

Synonym: Mkms_4688

Alternate gene names: 119870717

Gene position: 4912500-4914827 (Clockwise)

Preceding gene: 119870716

Following gene: 119870718

Centisome position: 85.62

GC content: 68.94

Gene sequence:

>2328_bases
ATGACCGACACCGTCGCCACCCGCTACTCGGGAACCCGGGTCGCGAGGGTCGAGGACAACCGCCTGCTGACCGGGCGCGG
GACCTTCGTCGACGACATCCAGCGCCCCGGCATGCTGCACGCGTGCTTCGTCCGCAGCCCGTTCGCCCGGGCCAAGGTCA
ACGGGATCGATGCCTCCGCCGCGCTGGCGATGCCCGGCGTGTACGCGGTGTTCACCGCCGAGGACCTCAACGGCGACGCC
GTCGAGTCGTGGCACGCCGTCGCCGGTAAGGACGTCCCCGACACCCCGCGCCCGCCGTTGGCCGAGGGCGAGGTGAAGTT
CGTCGGCGATCCCGTCGCGCTCGTCGTGGCCGAATCCCGTTACCTGGCCGAGGACGCCGCCGACGCCGTCCAGGTCGACT
ACGAGCCCCTGCCCGCGGTGGCCGACTTCCGCACCGCGGTGAACGCCGAAACCGTCGTCCACGAGCAGTACCCCGACAAC
GTCGCGGGCGGGATGGGTGGCGCGCCTCCGGACGAGGAGACGTTCTCGTCGGCCCCATGCGTGGTGAGCGAGAACATCTA
CCAGCAGATGTACGTGCCCGTCCCGATCGAGACCCGGGGCATGGTCGTCGAATGGGAGCCCACCACAGGCGAATTGACGC
TGTGGGCGTCCACGCAGACACCTCACGAGCTCCGCGCGTTCACCGCTCGGCTGCTCGGCATCCCCGCCCAGAAGGTCCGG
GTCATCATGCGCGACACCGGCGGCGGGTTCGGGCAGAAGGTCGTGCCGATGCGCGAGGACATGGTCATCATGCTGGCCGC
GCGCAAGGTCCCCGGTGCGCTGAAGTGGATCGAGGACCGGCGCGAGAACCTCATGTCGGCCGGCCAGTCCCGCCACGTCG
ACGGCACCGCCCGGATGGCGTTCGACGAGGACGGCACGATCCTCGCCGTCGACATCGACTTCAACCAGGACGTCGGCGCG
TATCCCACCCCGTACCCGGTGCTCACCACCGCGGCGATCGGCATGTTCTTCCCCGGGCCGTACCGCGTCCCGAAGGCCAG
CTTCAACTACAAGACGGTGTTCTCCAACACCGCCGGCCTGCACGCCTACCGCGGCCCGTGGCAGTACGAGACTCTGGCCC
GAGAGATCATGTTCGACATCGCCGCCCGCAAGCTGGGCATCGATCCGGTCGAGTTGCGCCGCAAGAACATCCTGCGCGGC
GACGAGATGCCGTACTTCAACCCCAACGGCATGCCGTATGACCACGTCGCCCCCGCCGACACCTTCGAACAGGCCGTCAA
GATCCTCGACCACGAGGGTTTCCGCAAGGAGCAGGCCGAGGCGCTCGCCCAGGGCCGCTACATCGGGCTCGGGTTCTCCG
CGTACATCGAGCCGACCGGCGCCGCGACCGGCCATCTGGGCACCGAAGGCTGCACCATCCGGATGGAGCCGACCGGCAAG
ATCAACGTCTACGTCAACGGCGGGTCGACCGGCAACAGCCTGGAGACGACGGTCATTCAGCTCACCGCCGACGCGCTCGG
CGCCGACATCGACGACGTCGCCACCATCCAGGGCGACACCGCGATCACCCCTTACGGGGCGGGCACGCAAGGCAGTAGGA
GTGCCCCGATGACCGCGGGCGCGGTCAACGAGGCCGGCGGCATCCTGCGCGCACAACTGATCCGCATGGCCGCCCACCAC
CTGGGCGTGGAAGTCGACGACATCGAACTCGGCGGGTCGAAGGCCTACGTACGCGAAGACCCCACCAAGAGTGTGAGTTT
CGCCGACATCGCCTACCGCGCGCACTACCAGCCCGAGCACCTGCCACCGGGCGGAACGGCGACGCTGGAGGCCACCGCGC
GCTTCACCTCGATGGCGATGATCCACTGGGCCAACGCCACTCACGCCTGCACGTGTGAGGTCGACGTGGAGACCGGACAG
GTGACGCTGACCCGTTACATCGTCAGCGAGGACGTCGGCCCGATGATCAACCCCAACGTGGTCGAGGGGCAGGTGGCCGG
CGGCACGGTGCAGGGCATCGGCGGCGCGCTGCTGGAGAGCCTGGTCTACGACGCCGACGGCAACCCGCTGTCGTCGACGT
TCGTCGACTATCTGCTGCCAACGGCGACCGAGGTGCCGCCGATCGAGTTCGGCCACGTCGAGATCCCCGGCCCGGGCGTC
GGCGGCTACAAGGGCGCCGGCGAAGGTGGCGCGATCGGCTCGACACCCGCCGTGATCAACGCGATCAACGACGCGCTCGC
CCCGCTGGGTGTGACCGTCACCCGGTTGCCCGCCACCCCCGCGACCATCGTCGAACTGCTCGAACAAGCGAACCGAGAGG
ACCACTAG

Upstream 100 bases:

>100_bases
GGGCCGCTTCCTTACCAATGTACGATAACGACACTCTTGCCGCGCGCTGGTCGGTACCACTTACGCGCAGAAGCAATCCG
ACGGAATGGAGCGTTCACCG

Downstream 100 bases:

>100_bases
CCGTGGAACTGAACAACGAATTCCGGGTCGCGGTGCCGGCCGCCAAGACCTGGGAGGTGCTCACCGACGTCGAGCGGGTG
GCGCCGTGCCTGCCCGGTGC

Product: xanthine dehydrogenase, molybdenum binding subunit apoprotein

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 775; Mature: 774

Protein sequence:

>775_residues
MTDTVATRYSGTRVARVEDNRLLTGRGTFVDDIQRPGMLHACFVRSPFARAKVNGIDASAALAMPGVYAVFTAEDLNGDA
VESWHAVAGKDVPDTPRPPLAEGEVKFVGDPVALVVAESRYLAEDAADAVQVDYEPLPAVADFRTAVNAETVVHEQYPDN
VAGGMGGAPPDEETFSSAPCVVSENIYQQMYVPVPIETRGMVVEWEPTTGELTLWASTQTPHELRAFTARLLGIPAQKVR
VIMRDTGGGFGQKVVPMREDMVIMLAARKVPGALKWIEDRRENLMSAGQSRHVDGTARMAFDEDGTILAVDIDFNQDVGA
YPTPYPVLTTAAIGMFFPGPYRVPKASFNYKTVFSNTAGLHAYRGPWQYETLAREIMFDIAARKLGIDPVELRRKNILRG
DEMPYFNPNGMPYDHVAPADTFEQAVKILDHEGFRKEQAEALAQGRYIGLGFSAYIEPTGAATGHLGTEGCTIRMEPTGK
INVYVNGGSTGNSLETTVIQLTADALGADIDDVATIQGDTAITPYGAGTQGSRSAPMTAGAVNEAGGILRAQLIRMAAHH
LGVEVDDIELGGSKAYVREDPTKSVSFADIAYRAHYQPEHLPPGGTATLEATARFTSMAMIHWANATHACTCEVDVETGQ
VTLTRYIVSEDVGPMINPNVVEGQVAGGTVQGIGGALLESLVYDADGNPLSSTFVDYLLPTATEVPPIEFGHVEIPGPGV
GGYKGAGEGGAIGSTPAVINAINDALAPLGVTVTRLPATPATIVELLEQANREDH

Sequences:

>Translated_775_residues
MTDTVATRYSGTRVARVEDNRLLTGRGTFVDDIQRPGMLHACFVRSPFARAKVNGIDASAALAMPGVYAVFTAEDLNGDA
VESWHAVAGKDVPDTPRPPLAEGEVKFVGDPVALVVAESRYLAEDAADAVQVDYEPLPAVADFRTAVNAETVVHEQYPDN
VAGGMGGAPPDEETFSSAPCVVSENIYQQMYVPVPIETRGMVVEWEPTTGELTLWASTQTPHELRAFTARLLGIPAQKVR
VIMRDTGGGFGQKVVPMREDMVIMLAARKVPGALKWIEDRRENLMSAGQSRHVDGTARMAFDEDGTILAVDIDFNQDVGA
YPTPYPVLTTAAIGMFFPGPYRVPKASFNYKTVFSNTAGLHAYRGPWQYETLAREIMFDIAARKLGIDPVELRRKNILRG
DEMPYFNPNGMPYDHVAPADTFEQAVKILDHEGFRKEQAEALAQGRYIGLGFSAYIEPTGAATGHLGTEGCTIRMEPTGK
INVYVNGGSTGNSLETTVIQLTADALGADIDDVATIQGDTAITPYGAGTQGSRSAPMTAGAVNEAGGILRAQLIRMAAHH
LGVEVDDIELGGSKAYVREDPTKSVSFADIAYRAHYQPEHLPPGGTATLEATARFTSMAMIHWANATHACTCEVDVETGQ
VTLTRYIVSEDVGPMINPNVVEGQVAGGTVQGIGGALLESLVYDADGNPLSSTFVDYLLPTATEVPPIEFGHVEIPGPGV
GGYKGAGEGGAIGSTPAVINAINDALAPLGVTVTRLPATPATIVELLEQANREDH
>Mature_774_residues
TDTVATRYSGTRVARVEDNRLLTGRGTFVDDIQRPGMLHACFVRSPFARAKVNGIDASAALAMPGVYAVFTAEDLNGDAV
ESWHAVAGKDVPDTPRPPLAEGEVKFVGDPVALVVAESRYLAEDAADAVQVDYEPLPAVADFRTAVNAETVVHEQYPDNV
AGGMGGAPPDEETFSSAPCVVSENIYQQMYVPVPIETRGMVVEWEPTTGELTLWASTQTPHELRAFTARLLGIPAQKVRV
IMRDTGGGFGQKVVPMREDMVIMLAARKVPGALKWIEDRRENLMSAGQSRHVDGTARMAFDEDGTILAVDIDFNQDVGAY
PTPYPVLTTAAIGMFFPGPYRVPKASFNYKTVFSNTAGLHAYRGPWQYETLAREIMFDIAARKLGIDPVELRRKNILRGD
EMPYFNPNGMPYDHVAPADTFEQAVKILDHEGFRKEQAEALAQGRYIGLGFSAYIEPTGAATGHLGTEGCTIRMEPTGKI
NVYVNGGSTGNSLETTVIQLTADALGADIDDVATIQGDTAITPYGAGTQGSRSAPMTAGAVNEAGGILRAQLIRMAAHHL
GVEVDDIELGGSKAYVREDPTKSVSFADIAYRAHYQPEHLPPGGTATLEATARFTSMAMIHWANATHACTCEVDVETGQV
TLTRYIVSEDVGPMINPNVVEGQVAGGTVQGIGGALLESLVYDADGNPLSSTFVDYLLPTATEVPPIEFGHVEIPGPGVG
GYKGAGEGGAIGSTPAVINAINDALAPLGVTVTRLPATPATIVELLEQANREDH

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI91823271, Length=707, Percent_Identity=24.6110325318246, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI71773480, Length=741, Percent_Identity=24.4264507422402, Blast_Score=125, Evalue=1e-28,
Organism=Escherichia coli, GI1789230, Length=786, Percent_Identity=30.1526717557252, Blast_Score=245, Evalue=9e-66,
Organism=Escherichia coli, GI1789246, Length=822, Percent_Identity=26.6423357664234, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1786478, Length=765, Percent_Identity=24.7058823529412, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17540638, Length=786, Percent_Identity=24.8091603053435, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17539860, Length=760, Percent_Identity=23.2894736842105, Blast_Score=116, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI32566215, Length=754, Percent_Identity=23.8726790450928, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17737937, Length=700, Percent_Identity=25.4285714285714, Blast_Score=155, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24647199, Length=782, Percent_Identity=23.6572890025575, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24647193, Length=783, Percent_Identity=23.7547892720307, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24647201, Length=791, Percent_Identity=22.75600505689, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 82716; Mature: 82585

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTVATRYSGTRVARVEDNRLLTGRGTFVDDIQRPGMLHACFVRSPFARAKVNGIDASA
CCCCCEECCCCCEEEEEECCEEEEECCCHHHHHCCCCCEEEEECCCCHHHHEECCCCCHH
ALAMPGVYAVFTAEDLNGDAVESWHAVAGKDVPDTPRPPLAEGEVKFVGDPVALVVAESR
HHHCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCEEEEEECCH
YLAEDAADAVQVDYEPLPAVADFRTAVNAETVVHEQYPDNVAGGMGGAPPDEETFSSAPC
HHHHHCCCCEEECCCCCCCHHHHHHHCCHHHEEECCCCCCCCCCCCCCCCCHHHCCCCCE
VVSENIYQQMYVPVPIETRGMVVEWEPTTGELTLWASTQTPHELRAFTARLLGIPAQKVR
EEECCHHHHEEECCCCCCCCEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHEE
VIMRDTGGGFGQKVVPMREDMVIMLAARKVPGALKWIEDRRENLMSAGQSRHVDGTARMA
EEEEECCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
FDEDGTILAVDIDFNQDVGAYPTPYPVLTTAAIGMFFPGPYRVPKASFNYKTVFSNTAGL
ECCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCC
HAYRGPWQYETLAREIMFDIAARKLGIDPVELRRKNILRGDEMPYFNPNGMPYDHVAPAD
CCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHH
TFEQAVKILDHEGFRKEQAEALAQGRYIGLGFSAYIEPTGAATGHLGTEGCTIRMEPTGK
HHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCCCCCEEEECCCCE
INVYVNGGSTGNSLETTVIQLTADALGADIDDVATIQGDTAITPYGAGTQGSRSAPMTAG
EEEEEECCCCCCCCEEEEEEEEHHHHCCCCCHHEEECCCCEECCCCCCCCCCCCCCCCCC
AVNEAGGILRAQLIRMAAHHLGVEVDDIELGGSKAYVREDPTKSVSFADIAYRAHYQPEH
CCHHCCHHHHHHHHHHHHHHHCCEEEEEEECCCEEEEECCCCCCCCHHHEEEEECCCCCC
LPPGGTATLEATARFTSMAMIHWANATHACTCEVDVETGQVTLTRYIVSEDVGPMINPNV
CCCCCCEEEEEHHHHHEEEEEEECCCCEEEEEEEECCCCCEEEEEEEEHHCCCCCCCCCE
VEGQVAGGTVQGIGGALLESLVYDADGNPLSSTFVDYLLPTATEVPPIEFGHVEIPGPGV
EECEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEECCCCCC
GGYKGAGEGGAIGSTPAVINAINDALAPLGVTVTRLPATPATIVELLEQANREDH
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TDTVATRYSGTRVARVEDNRLLTGRGTFVDDIQRPGMLHACFVRSPFARAKVNGIDASA
CCCCEECCCCCEEEEEECCEEEEECCCHHHHHCCCCCEEEEECCCCHHHHEECCCCCHH
ALAMPGVYAVFTAEDLNGDAVESWHAVAGKDVPDTPRPPLAEGEVKFVGDPVALVVAESR
HHHCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCEEEEEECCH
YLAEDAADAVQVDYEPLPAVADFRTAVNAETVVHEQYPDNVAGGMGGAPPDEETFSSAPC
HHHHHCCCCEEECCCCCCCHHHHHHHCCHHHEEECCCCCCCCCCCCCCCCCHHHCCCCCE
VVSENIYQQMYVPVPIETRGMVVEWEPTTGELTLWASTQTPHELRAFTARLLGIPAQKVR
EEECCHHHHEEECCCCCCCCEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHEE
VIMRDTGGGFGQKVVPMREDMVIMLAARKVPGALKWIEDRRENLMSAGQSRHVDGTARMA
EEEEECCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
FDEDGTILAVDIDFNQDVGAYPTPYPVLTTAAIGMFFPGPYRVPKASFNYKTVFSNTAGL
ECCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCC
HAYRGPWQYETLAREIMFDIAARKLGIDPVELRRKNILRGDEMPYFNPNGMPYDHVAPAD
CCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHH
TFEQAVKILDHEGFRKEQAEALAQGRYIGLGFSAYIEPTGAATGHLGTEGCTIRMEPTGK
HHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCCCCCEEEECCCCE
INVYVNGGSTGNSLETTVIQLTADALGADIDDVATIQGDTAITPYGAGTQGSRSAPMTAG
EEEEEECCCCCCCCEEEEEEEEHHHHCCCCCHHEEECCCCEECCCCCCCCCCCCCCCCCC
AVNEAGGILRAQLIRMAAHHLGVEVDDIELGGSKAYVREDPTKSVSFADIAYRAHYQPEH
CCHHCCHHHHHHHHHHHHHHHCCEEEEEEECCCEEEEECCCCCCCCHHHEEEEECCCCCC
LPPGGTATLEATARFTSMAMIHWANATHACTCEVDVETGQVTLTRYIVSEDVGPMINPNV
CCCCCCEEEEEHHHHHEEEEEEECCCCEEEEEEEECCCCCEEEEEEEEHHCCCCCCCCCE
VEGQVAGGTVQGIGGALLESLVYDADGNPLSSTFVDYLLPTATEVPPIEFGHVEIPGPGV
EECEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEECCCCCC
GGYKGAGEGGAIGSTPAVINAINDALAPLGVTVTRLPATPATIVELLEQANREDH
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]