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The map label for this gene is arsC [H]

Identifier: 119870637

GI number: 119870637

Start: 4838015

End: 4838668

Strand: Direct

Name: arsC [H]

Synonym: Mkms_4608

Alternate gene names: 119870637

Gene position: 4838015-4838668 (Clockwise)

Preceding gene: 119870636

Following gene: 119870642

Centisome position: 84.33

GC content: 68.2

Gene sequence:

>654_bases
ATGTCCGACCACATGCGACCCAACCCGTCCCTCGACCAGGAGCTGGCCCTCCGGGTCGCGGGCACCCGACTCGAGGAGGA
GTTCGCCGGCGTGTTCGACGCCGAGACCGTCGAGCGTTTCCTGCACTCCGCCTACCACCGGTTCGCCGGTCACGCGTCGG
TCCCGAACTTCCTGCCGCTGCTCGCCGAGCGGTTCGCGCACCAACAGTTGCGAGCGCTCGCCAAGGTCGAGGGCAAGGGC
CACGACGGCAAGCCCGTCGTGCTGTTCCTCTGCACGCACAATGCAGGGCGATCACAGATGGCACTGGGATTCTTCACCCA
CCTCGCCGGCGACGCCGCGGTCGCGTGGTCAGGGGGTTCCGAGCCGGGCGACGAGATCAATCCGGCCGCGGTCGAGGCGA
TGGCCGAACGTGGTGTCGACATCTCCGGCGAATACCCGAAGCCGTGGACCGACGAGATCGTCCGAGCCGCCGACGTGGTG
ATCTCCATGGGCTGCGGTGACGCGTGCCCGGTCTTTCCGGGACGGCGCTACGAAGAATGGAAGCTCGACGATCCGGCCGG
TATGGGAGTCGACGCGGTACGCCCCATCCGCGACGACATCGAACGCCGGGTTCGCGGACTGCTGGCCGAACTCGGGGTCA
CCGTCGAGGCGTGA

Upstream 100 bases:

>100_bases
CGCCGCAGCGGGATGCCTTCGACACCGCGCTGCGGGAACTGACTGACCGCGTCCAGCACTTCCTGGCCGCCCTGACACCG
ACCTGACAGGAAAGAGCCCG

Downstream 100 bases:

>100_bases
ACCTCGCGGTCACTCCGGCGGTCGAACAACACCGACCGGCCGGGAGAAGCGGCGGCGCAGGGCGAGTGAGACGTACACCA
GGGCGACCAGGACGGGCACC

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MSDHMRPNPSLDQELALRVAGTRLEEEFAGVFDAETVERFLHSAYHRFAGHASVPNFLPLLAERFAHQQLRALAKVEGKG
HDGKPVVLFLCTHNAGRSQMALGFFTHLAGDAAVAWSGGSEPGDEINPAAVEAMAERGVDISGEYPKPWTDEIVRAADVV
ISMGCGDACPVFPGRRYEEWKLDDPAGMGVDAVRPIRDDIERRVRGLLAELGVTVEA

Sequences:

>Translated_217_residues
MSDHMRPNPSLDQELALRVAGTRLEEEFAGVFDAETVERFLHSAYHRFAGHASVPNFLPLLAERFAHQQLRALAKVEGKG
HDGKPVVLFLCTHNAGRSQMALGFFTHLAGDAAVAWSGGSEPGDEINPAAVEAMAERGVDISGEYPKPWTDEIVRAADVV
ISMGCGDACPVFPGRRYEEWKLDDPAGMGVDAVRPIRDDIERRVRGLLAELGVTVEA
>Mature_216_residues
SDHMRPNPSLDQELALRVAGTRLEEEFAGVFDAETVERFLHSAYHRFAGHASVPNFLPLLAERFAHQQLRALAKVEGKGH
DGKPVVLFLCTHNAGRSQMALGFFTHLAGDAAVAWSGGSEPGDEINPAAVEAMAERGVDISGEYPKPWTDEIVRAADVVI
SMGCGDACPVFPGRRYEEWKLDDPAGMGVDAVRPIRDDIERRVRGLLAELGVTVEA

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 23617; Mature: 23486

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDHMRPNPSLDQELALRVAGTRLEEEFAGVFDAETVERFLHSAYHRFAGHASVPNFLPL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHH
LAERFAHQQLRALAKVEGKGHDGKPVVLFLCTHNAGRSQMALGFFTHLAGDAAVAWSGGS
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCC
EPGDEINPAAVEAMAERGVDISGEYPKPWTDEIVRAADVVISMGCGDACPVFPGRRYEEW
CCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
KLDDPAGMGVDAVRPIRDDIERRVRGLLAELGVTVEA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SDHMRPNPSLDQELALRVAGTRLEEEFAGVFDAETVERFLHSAYHRFAGHASVPNFLPL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHH
LAERFAHQQLRALAKVEGKGHDGKPVVLFLCTHNAGRSQMALGFFTHLAGDAAVAWSGGS
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCC
EPGDEINPAAVEAMAERGVDISGEYPKPWTDEIVRAADVVISMGCGDACPVFPGRRYEEW
CCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
KLDDPAGMGVDAVRPIRDDIERRVRGLLAELGVTVEA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA