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The map label for this gene is desA1 [H]

Identifier: 119870627

GI number: 119870627

Start: 4827195

End: 4828190

Strand: Direct

Name: desA1 [H]

Synonym: Mkms_4598

Alternate gene names: 119870627

Gene position: 4827195-4828190 (Clockwise)

Preceding gene: 119870626

Following gene: 119870628

Centisome position: 84.14

GC content: 65.26

Gene sequence:

>996_bases
ATGCACGAAAACCTGACCGACCTGCACCTGCTTCACGAGCTGGAGCCGGTCGTCGAGAAGCTGCTCAACCGGCACCTGAC
CATGCACAAGGACTGGAACCCGCACGACTTCATCCCGTGGTCGGACGGCAAGAACTACTACGCCCTCGGCGGCCAGGACT
GGGATCCCGAGCAGTCGAAGCTGTCCGAGGTCGCCCAGACCGCGATGGTGCAGAACCTGCTCACCGAGGACAACCTGCCC
TCGTATCACCGCGAGATCGCGATGAACATGAGCATGGACGGCGCGTGGGGCCAGTGGGTCAACCGCTGGACCGCCGAGGA
GAACCGGCACGGCATCGCGCTGCGCGACTACCTCGTCGTCACCCGCGCGGTCGACCCCGTCCAGCTCGAGGAACTGCGCG
TCGAGCAGATGACCCGTGGCTTCTCTCCCGGCCAGAACCAGCAGGGCGACCTCTTCGCCGAGAGCCTGTTCGACTCGGTC
ATCTACGTGACCTTCCAGGAACTCGCCACCCGCGTCTCGCACCGCAACACCGGCAAGGCCTGTCAGGATCCGGTCGCCGA
CCAGCTCCTGCAGCGGGTGTCGGCCGACGAGAACCTGCACATGATCTTCTACCGCGACGTGTCCGAGGCCGGCTTCGACA
TCGCGCCCGACCAGGCCATGCACTCGCTGCACCGGGTGCTGCGCAACTTCAAGATGCCCGGCTACACCGTGCCGGAGTTC
CGCCGCAAGGCCGTGATCATCGCCGTCGGCGGTGTCTACGATCCGCGGATCCACCTCGACGACGTGGTGATGCCGGTGCT
CAAGAAGTGGCGCATCTTCGAGCGCGAGGACTTCACCGGTGAGGCCGCCCGCATGCGCGACGACCTCGGCGTGCTGGTCG
AGGAACTCAAGGAGGCCTGCGAGAAGTTCGAGACGGCCAAGCAGAAGCGTCTCGAACGCGAAGCCAAGATGGCCGAGAAG
AAGGCCGGAAAGGTCCTCGCGTCATCAGCGTCGTAG

Upstream 100 bases:

>100_bases
ACCCAAACTTGATGTCACCGACGTACACAGATACTCTGACTGCAACCAACGGGCACAGATAACGCCGACGGGCTCCCGCA
CGCGAGGAGGACAACGGGAC

Downstream 100 bases:

>100_bases
CACCTCCCGCCGATACGGCCCGGTCTGCAGCCCTGCGGATCGGGCCGCTGGCATTGCCGAGCCCCGTGGTGCTGGCCCCG
ATGGCCGGGGTGACCAACGT

Product: fatty acid desaturase, type 2

Products: NA

Alternate protein names: DES; Putative acyl-ACP desaturase desA1 [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MHENLTDLHLLHELEPVVEKLLNRHLTMHKDWNPHDFIPWSDGKNYYALGGQDWDPEQSKLSEVAQTAMVQNLLTEDNLP
SYHREIAMNMSMDGAWGQWVNRWTAEENRHGIALRDYLVVTRAVDPVQLEELRVEQMTRGFSPGQNQQGDLFAESLFDSV
IYVTFQELATRVSHRNTGKACQDPVADQLLQRVSADENLHMIFYRDVSEAGFDIAPDQAMHSLHRVLRNFKMPGYTVPEF
RRKAVIIAVGGVYDPRIHLDDVVMPVLKKWRIFEREDFTGEAARMRDDLGVLVEELKEACEKFETAKQKRLEREAKMAEK
KAGKVLASSAS

Sequences:

>Translated_331_residues
MHENLTDLHLLHELEPVVEKLLNRHLTMHKDWNPHDFIPWSDGKNYYALGGQDWDPEQSKLSEVAQTAMVQNLLTEDNLP
SYHREIAMNMSMDGAWGQWVNRWTAEENRHGIALRDYLVVTRAVDPVQLEELRVEQMTRGFSPGQNQQGDLFAESLFDSV
IYVTFQELATRVSHRNTGKACQDPVADQLLQRVSADENLHMIFYRDVSEAGFDIAPDQAMHSLHRVLRNFKMPGYTVPEF
RRKAVIIAVGGVYDPRIHLDDVVMPVLKKWRIFEREDFTGEAARMRDDLGVLVEELKEACEKFETAKQKRLEREAKMAEK
KAGKVLASSAS
>Mature_331_residues
MHENLTDLHLLHELEPVVEKLLNRHLTMHKDWNPHDFIPWSDGKNYYALGGQDWDPEQSKLSEVAQTAMVQNLLTEDNLP
SYHREIAMNMSMDGAWGQWVNRWTAEENRHGIALRDYLVVTRAVDPVQLEELRVEQMTRGFSPGQNQQGDLFAESLFDSV
IYVTFQELATRVSHRNTGKACQDPVADQLLQRVSADENLHMIFYRDVSEAGFDIAPDQAMHSLHRVLRNFKMPGYTVPEF
RRKAVIIAVGGVYDPRIHLDDVVMPVLKKWRIFEREDFTGEAARMRDDLGVLVEELKEACEKFETAKQKRLEREAKMAEK
KAGKVLASSAS

Specific function: Could be involved in mycobacterial fatty acid biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005067
- InterPro:   IPR009078
- InterPro:   IPR012348 [H]

Pfam domain/function: PF03405 FA_desaturase_2 [H]

EC number: NA

Molecular weight: Translated: 38101; Mature: 38101

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHENLTDLHLLHELEPVVEKLLNRHLTMHKDWNPHDFIPWSDGKNYYALGGQDWDPEQSK
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHH
LSEVAQTAMVQNLLTEDNLPSYHREIAMNMSMDGAWGQWVNRWTAEENRHGIALRDYLVV
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHH
TRAVDPVQLEELRVEQMTRGFSPGQNQQGDLFAESLFDSVIYVTFQELATRVSHRNTGKA
HHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
CQDPVADQLLQRVSADENLHMIFYRDVSEAGFDIAPDQAMHSLHRVLRNFKMPGYTVPEF
HCCHHHHHHHHHHCCCCCEEEEEEECHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHH
RRKAVIIAVGGVYDPRIHLDDVVMPVLKKWRIFEREDFTGEAARMRDDLGVLVEELKEAC
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
EKFETAKQKRLEREAKMAEKKAGKVLASSAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHENLTDLHLLHELEPVVEKLLNRHLTMHKDWNPHDFIPWSDGKNYYALGGQDWDPEQSK
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHH
LSEVAQTAMVQNLLTEDNLPSYHREIAMNMSMDGAWGQWVNRWTAEENRHGIALRDYLVV
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHH
TRAVDPVQLEELRVEQMTRGFSPGQNQQGDLFAESLFDSVIYVTFQELATRVSHRNTGKA
HHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
CQDPVADQLLQRVSADENLHMIFYRDVSEAGFDIAPDQAMHSLHRVLRNFKMPGYTVPEF
HCCHHHHHHHHHHCCCCCEEEEEEECHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHH
RRKAVIIAVGGVYDPRIHLDDVVMPVLKKWRIFEREDFTGEAARMRDDLGVLVEELKEAC
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
EKFETAKQKRLEREAKMAEKKAGKVLASSAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036 [H]