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The map label for this gene is norD [H]

Identifier: 119870533

GI number: 119870533

Start: 4737124

End: 4738656

Strand: Direct

Name: norD [H]

Synonym: Mkms_4504

Alternate gene names: 119870533

Gene position: 4737124-4738656 (Clockwise)

Preceding gene: 119870532

Following gene: 119870534

Centisome position: 82.57

GC content: 68.95

Gene sequence:

>1533_bases
ATGTCCGAACTGTCCGACGCACACGCCATGGCGGTCGAGCGCAGCTGCGCGCTGACCGCGGTGGCGCTGAGCGGACGCCG
CCGCTCGGGCGCCCAGCTGGTGACCGGCCAACATCGTGGATTCGGCCTCGATGCCGCACTCGAGATCATCCGGGTCCCCT
ACCCCTCGACGCGTCGTGACTGGACCCGACGGTCCCTGACATGCGGTGTGGCGCTGCAGTGTTCACCGTCCAAGGAAGCG
CTTGCCGACTATCGTCTGAACGAGTTGACCACCCGCGAACTCCTGGCGCTCACCCTCGTGGAGGCCGGTGTCGCGACGCG
CTGGATCGCCTCGAACTGGCCCGGCCTGATCAGCGAACTGCATCGGTTGGTGCCCGACCTCGTCGCGACCTCGACGGACC
TGGACGCCGCGCAGATGCTCGAACGTGCGGTGACGCTGGCGCGTACGGGCCGACCGCTGACCGTCGACCCGTTGCTGGGG
AACTTGCCACGCGCTCACACCGACCCGCAGGGGCTGGCCGACACGCTGCGGCGCACGCTCGGCAGGTTGCCGTGGACAAC
CACCCAGAAGCGGCTCCCCCGTGCCCATTCCGTGCCGGTGGGCGGTGACGGCGGCATCCGCAATCCGAATCTGCCGCCAC
CGAGCCGACCGCAGGACAACGATCTCGACATCACCCCGGACCACCGGCCGGGCATCCCGTATCCGGAGTGGAATGCCTGG
ACGAAGAGCTTCATGCCCGATCACGTCGCGGTGGTGGAACGCAAGTACGCCAGCCGAACCCGCCAACCCGCGTCGGGCTC
GCCCGAGTTGCGCAGGTGGTTTGAGGAGCACACCCACAGAACCATCCGGAACCGGCAGGAGGACGGGTCGGATCTCGATG
TCGCACAATACGTCGACCACTTCATCGACGTACGGACGGGGGAGGCCGTCGAACCCCGGATCTTTCGGGAGCTGCTCCCC
GGCAGCCGCGACGTGACCACCGCGCTGTTGCTGGACGGCAGCTCGTCGCTGGGCGTCCACGGCGGCACGATCTTCCGGCT
GGAGTTGGCCTGCGCCGATGCGTTGTCGCGGGCGATGACGGCAGCCCGGGAACGCCACGGCATCTTCGTCTTCACCGGCA
ACACCCGGCATCGCGTCGAGGTGAACTGCCTCAAGGACTTCGAGGAGCGCCGTTTCGTCCCACCGGGCAGCCTCGGGCTG
TCCACCGGCGGATACACCCGCCTCGGTGCGCCGTTGCGGCACCTCACCAGCCGCCTGCTCGTGCAGCCGTCCGAGCGGCG
GCTGATCATCGTCATCGGTGACGGGCTGATCTCCGACGAGGGCTACGAGGGCCGCTACGCCTGGGCGGATGCCGCGCACG
CGGTCGAGGAGGCCGAAGACGCCGGGGTGTCGATGTACTACGTCGGCGTCGGCCCCACCCGGGTCGACCCGCTCCCGGAA
GTGTTCGGCCCGAGGCGTTCCCAACGCATCCGGCGCGTCGAAGAACTTCCCCGCGTCCTCGCCCACGTCCATCGGGAGCT
GGTGTCCGCATGA

Upstream 100 bases:

>100_bases
TGGGAAATCCTCCGCTACGTCGCCGCCTGGGGCGGAACCGGTTTGATCATCTGGTTCTGGTACTGGATGTTCTCCAACAT
CGGCACATTCTGAACTCGCG

Downstream 100 bases:

>100_bases
CAATCGACGAGCGCTTGCGCGAGGAGCCATGACCACAGACACCTACTACGCCAACGGCACCGAGGTCCAGCTCTTCGAGC
AGGCGTTCCACCAGCGGCTG

Product: MorD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 510; Mature: 509

Protein sequence:

>510_residues
MSELSDAHAMAVERSCALTAVALSGRRRSGAQLVTGQHRGFGLDAALEIIRVPYPSTRRDWTRRSLTCGVALQCSPSKEA
LADYRLNELTTRELLALTLVEAGVATRWIASNWPGLISELHRLVPDLVATSTDLDAAQMLERAVTLARTGRPLTVDPLLG
NLPRAHTDPQGLADTLRRTLGRLPWTTTQKRLPRAHSVPVGGDGGIRNPNLPPPSRPQDNDLDITPDHRPGIPYPEWNAW
TKSFMPDHVAVVERKYASRTRQPASGSPELRRWFEEHTHRTIRNRQEDGSDLDVAQYVDHFIDVRTGEAVEPRIFRELLP
GSRDVTTALLLDGSSSLGVHGGTIFRLELACADALSRAMTAARERHGIFVFTGNTRHRVEVNCLKDFEERRFVPPGSLGL
STGGYTRLGAPLRHLTSRLLVQPSERRLIIVIGDGLISDEGYEGRYAWADAAHAVEEAEDAGVSMYYVGVGPTRVDPLPE
VFGPRRSQRIRRVEELPRVLAHVHRELVSA

Sequences:

>Translated_510_residues
MSELSDAHAMAVERSCALTAVALSGRRRSGAQLVTGQHRGFGLDAALEIIRVPYPSTRRDWTRRSLTCGVALQCSPSKEA
LADYRLNELTTRELLALTLVEAGVATRWIASNWPGLISELHRLVPDLVATSTDLDAAQMLERAVTLARTGRPLTVDPLLG
NLPRAHTDPQGLADTLRRTLGRLPWTTTQKRLPRAHSVPVGGDGGIRNPNLPPPSRPQDNDLDITPDHRPGIPYPEWNAW
TKSFMPDHVAVVERKYASRTRQPASGSPELRRWFEEHTHRTIRNRQEDGSDLDVAQYVDHFIDVRTGEAVEPRIFRELLP
GSRDVTTALLLDGSSSLGVHGGTIFRLELACADALSRAMTAARERHGIFVFTGNTRHRVEVNCLKDFEERRFVPPGSLGL
STGGYTRLGAPLRHLTSRLLVQPSERRLIIVIGDGLISDEGYEGRYAWADAAHAVEEAEDAGVSMYYVGVGPTRVDPLPE
VFGPRRSQRIRRVEELPRVLAHVHRELVSA
>Mature_509_residues
SELSDAHAMAVERSCALTAVALSGRRRSGAQLVTGQHRGFGLDAALEIIRVPYPSTRRDWTRRSLTCGVALQCSPSKEAL
ADYRLNELTTRELLALTLVEAGVATRWIASNWPGLISELHRLVPDLVATSTDLDAAQMLERAVTLARTGRPLTVDPLLGN
LPRAHTDPQGLADTLRRTLGRLPWTTTQKRLPRAHSVPVGGDGGIRNPNLPPPSRPQDNDLDITPDHRPGIPYPEWNAWT
KSFMPDHVAVVERKYASRTRQPASGSPELRRWFEEHTHRTIRNRQEDGSDLDVAQYVDHFIDVRTGEAVEPRIFRELLPG
SRDVTTALLLDGSSSLGVHGGTIFRLELACADALSRAMTAARERHGIFVFTGNTRHRVEVNCLKDFEERRFVPPGSLGLS
TGGYTRLGAPLRHLTSRLLVQPSERRLIIVIGDGLISDEGYEGRYAWADAAHAVEEAEDAGVSMYYVGVGPTRVDPLPEV
FGPRRSQRIRRVEELPRVLAHVHRELVSA

Specific function: Part of the operon norEFCBQD encoding nitric oxide reductase. Essential virulence factor, probably involved in the detoxification of nitric oxide (NO) produced in the macrophages during the innate response against infection [H]

COG id: COG4548

COG function: function code P; Nitric oxide reductase activation protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 VWFA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002035 [H]

Pfam domain/function: PF00092 VWA [H]

EC number: NA

Molecular weight: Translated: 56500; Mature: 56369

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: PS50234 VWFA ; PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELSDAHAMAVERSCALTAVALSGRRRSGAQLVTGQHRGFGLDAALEIIRVPYPSTRRD
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHCCCCCCCCHH
WTRRSLTCGVALQCSPSKEALADYRLNELTTRELLALTLVEAGVATRWIASNWPGLISEL
HHHHHEEECEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
HRLVPDLVATSTDLDAAQMLERAVTLARTGRPLTVDPLLGNLPRAHTDPQGLADTLRRTL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEECHHHCCCCCCCCCHHHHHHHHHHHH
GRLPWTTTQKRLPRAHSVPVGGDGGIRNPNLPPPSRPQDNDLDITPDHRPGIPYPEWNAW
HCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
TKSFMPDHVAVVERKYASRTRQPASGSPELRRWFEEHTHRTIRNRQEDGSDLDVAQYVDH
HHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
FIDVRTGEAVEPRIFRELLPGSRDVTTALLLDGSSSLGVHGGTIFRLELACADALSRAMT
HHCCCCCCCCCHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHH
AARERHGIFVFTGNTRHRVEVNCLKDFEERRFVPPGSLGLSTGGYTRLGAPLRHLTSRLL
HHHHHCCEEEEECCCCEEEEHHHHHHHHHCCCCCCCCCCCCCCCCHHHCHHHHHHHHHHH
VQPSERRLIIVIGDGLISDEGYEGRYAWADAAHAVEEAEDAGVSMYYVGVGPTRVDPLPE
CCCCCCEEEEEECCCEECCCCCCCCEEHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHH
VFGPRRSQRIRRVEELPRVLAHVHRELVSA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SELSDAHAMAVERSCALTAVALSGRRRSGAQLVTGQHRGFGLDAALEIIRVPYPSTRRD
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHCCCCCCCCHH
WTRRSLTCGVALQCSPSKEALADYRLNELTTRELLALTLVEAGVATRWIASNWPGLISEL
HHHHHEEECEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
HRLVPDLVATSTDLDAAQMLERAVTLARTGRPLTVDPLLGNLPRAHTDPQGLADTLRRTL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEECHHHCCCCCCCCCHHHHHHHHHHHH
GRLPWTTTQKRLPRAHSVPVGGDGGIRNPNLPPPSRPQDNDLDITPDHRPGIPYPEWNAW
HCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
TKSFMPDHVAVVERKYASRTRQPASGSPELRRWFEEHTHRTIRNRQEDGSDLDVAQYVDH
HHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
FIDVRTGEAVEPRIFRELLPGSRDVTTALLLDGSSSLGVHGGTIFRLELACADALSRAMT
HHCCCCCCCCCHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHH
AARERHGIFVFTGNTRHRVEVNCLKDFEERRFVPPGSLGLSTGGYTRLGAPLRHLTSRLL
HHHHHCCEEEEECCCCEEEEHHHHHHHHHCCCCCCCCCCCCCCCCHHHCHHHHHHHHHHH
VQPSERRLIIVIGDGLISDEGYEGRYAWADAAHAVEEAEDAGVSMYYVGVGPTRVDPLPE
CCCCCCEEEEEECCCEECCCCCCCCEEHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHH
VFGPRRSQRIRRVEELPRVLAHVHRELVSA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA