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The map label for this gene is ygfA [H]

Identifier: 119870406

GI number: 119870406

Start: 4598231

End: 4598824

Strand: Direct

Name: ygfA [H]

Synonym: Mkms_4377

Alternate gene names: 119870406

Gene position: 4598231-4598824 (Clockwise)

Preceding gene: 119870397

Following gene: 119870407

Centisome position: 80.15

GC content: 73.23

Gene sequence:

>594_bases
GTGACGTCGCCGACGAAGTCCGAGATGCGCGCGCAGGTGTTGCAGGCACGCCGCAAAGTGACGCCGGAGACGCAGGAGCG
CGAGGCCGCCGCGCTCGCCGCGCACCTTGCTGAAATCGCCGCGCCCGGTCGAACCGTGTGCGCCTACGTGCCGATCGGTT
CCGAGCCGGGGTCGCTCGCGATGCTGGACGAGCTGCTGGCACGCGGCGCGCGGGTCCTGCTGCCGGTGGCTCGGCACGAC
GAGGCCGGCGTCCCGGCGCCGCTGCGGTGGGGTGAGTATCGTCCGGGGCGGTTGGCCGACGCGCAGTTCGGACTGCGCGA
ACCGGCGCCACCGTGGCTGACGGCCGATGCGGTGGCCGAGGCCGACGTCGTACTCGTCCCGGCGTTGGCGGTGGACCGCT
GCGGGGTGCGACTGGGGCGCGGCGCGGGGTTCTACGACCGCTCGCTGGGGCGGGCTGATTCGGCGGCGTTGCTGGTGGCG
GTGGTGCGCGACGAGGAAGTCGTCGACCGGGTACCGGGGGAAGCCCACGACGTGCGGATGACGCATGCGCTGACGCCGGG
GTGTGGACTGGTCGCTCTGCGGGAATCACAGTGA

Upstream 100 bases:

>100_bases
ACTTCTGGCCGACTCATCGCAGACAGATTAACCGTTGGGCGCAGGTTGAACCCGTTATGGCGGCACCTCGATTTCGCGGA
CGGGATGACATCGTGGAGGT

Downstream 100 bases:

>100_bases
CCGCGTAGCGGTTCTAGCACTTGAGCCGGTAGAGTGCTAACAAGTTTGACGACCTCGGAGGTTTTCGTGCCTACCTATTC
CTATGCGTGCACCGAATGCG

Product: 5-formyltetrahydrofolate cyclo-ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MTSPTKSEMRAQVLQARRKVTPETQEREAAALAAHLAEIAAPGRTVCAYVPIGSEPGSLAMLDELLARGARVLLPVARHD
EAGVPAPLRWGEYRPGRLADAQFGLREPAPPWLTADAVAEADVVLVPALAVDRCGVRLGRGAGFYDRSLGRADSAALLVA
VVRDEEVVDRVPGEAHDVRMTHALTPGCGLVALRESQ

Sequences:

>Translated_197_residues
MTSPTKSEMRAQVLQARRKVTPETQEREAAALAAHLAEIAAPGRTVCAYVPIGSEPGSLAMLDELLARGARVLLPVARHD
EAGVPAPLRWGEYRPGRLADAQFGLREPAPPWLTADAVAEADVVLVPALAVDRCGVRLGRGAGFYDRSLGRADSAALLVA
VVRDEEVVDRVPGEAHDVRMTHALTPGCGLVALRESQ
>Mature_196_residues
TSPTKSEMRAQVLQARRKVTPETQEREAAALAAHLAEIAAPGRTVCAYVPIGSEPGSLAMLDELLARGARVLLPVARHDE
AGVPAPLRWGEYRPGRLADAQFGLREPAPPWLTADAVAEADVVLVPALAVDRCGVRLGRGAGFYDRSLGRADSAALLVAV
VRDEEVVDRVPGEAHDVRMTHALTPGCGLVALRESQ

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Escherichia coli, GI1789278, Length=177, Percent_Identity=28.2485875706215, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: NA

Molecular weight: Translated: 20939; Mature: 20808

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPTKSEMRAQVLQARRKVTPETQEREAAALAAHLAEIAAPGRTVCAYVPIGSEPGSLA
CCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHH
MLDELLARGARVLLPVARHDEAGVPAPLRWGEYRPGRLADAQFGLREPAPPWLTADAVAE
HHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHCC
ADVVLVPALAVDRCGVRLGRGAGFYDRSLGRADSAALLVAVVRDEEVVDRVPGEAHDVRM
CCEEEECHHHHHHCCCEECCCCCCHHHHCCCCCCCEEEEEEECCHHHHHHCCCCHHHEEE
THALTPGCGLVALRESQ
EEECCCCCCEEEEECCC
>Mature Secondary Structure 
TSPTKSEMRAQVLQARRKVTPETQEREAAALAAHLAEIAAPGRTVCAYVPIGSEPGSLA
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHH
MLDELLARGARVLLPVARHDEAGVPAPLRWGEYRPGRLADAQFGLREPAPPWLTADAVAE
HHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHCC
ADVVLVPALAVDRCGVRLGRGAGFYDRSLGRADSAALLVAVVRDEEVVDRVPGEAHDVRM
CCEEEECHHHHHHCCCEECCCCCCHHHHCCCCCCCEEEEEEECCHHHHHHCCCCHHHEEE
THALTPGCGLVALRESQ
EEECCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]