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The map label for this gene is IS1086 [H]

Identifier: 119870142

GI number: 119870142

Start: 4344043

End: 4345602

Strand: Direct

Name: IS1086 [H]

Synonym: Mkms_4112

Alternate gene names: 119870142

Gene position: 4344043-4345602 (Clockwise)

Preceding gene: 119870141

Following gene: 119870143

Centisome position: 75.72

GC content: 64.62

Gene sequence:

>1560_bases
GTGTCGTTTTCGGAGGACTGTGTCCGGTTTGGGGATCGGCTAGCGCGGTTGGTTGATGCCGGGGTGCCGGTGAAGGAGGC
GGCGGTCGCTACTGGGGTTTCGCGTGACCGGTGTTATGCGATTCTGCGGGCGATCGGCCGGCCTGTCGGGCAGGCCCGTG
GTCGGGGTGAGCGCGCTGATCAGCGTGGGGTGGCCGACCTGGGTGTGGTCGTGGCCGTATTCAAGGACACCGGTTCGATC
CTGCAGGCGGCCACAGCGTGTGGGGTGTCGCATTCGACGGCACGCAAACTGTTGGTCGCCGAGGGGCTGGTGACCAGCGG
GAAGATCCCGTGGGGCAAGCCCGAGGCGAAACGTCGGTGCTTGGAGCTGTTCGAGCAGGGTTGGTCCACCGGGGCAGCGG
CGCGGGAGGTCGGTGTCAACGTGCGGACCGCGCGGGACTGGCGCAAGGGGATCCGGCACACCAACAACACGCGGGTTCAC
CCCGATGGTCGGGTCGTGGACTACACCGACCGGACCGTCTACAAACAGTCGGTGAGCAACCTGATCTGCGATGACACCGG
ACGGCCGGCCATCGATGACCGGTATCTGTCGGTCCAGGACCGAGTGGCGATCGCCGATGGCCTCCTCGGGAAGGAGTCGT
TACGGACGATCGCCGGGCGGATCGGCAAAAACGTTTCCACGGTGTCGCGGGAGATTCGTGCGCGCAGCATTGATGGCCGC
TATCTGCCGTATCACGCCGATCGGGCGGCGGCCTCGGCCCGGGCTCGGCCCAAGCAGTCCAAACTGGTGGTCAACGTGGT
CCTGCGGGGAGCGGTTGAAGAAGGCCTGTCGCGCAAGCTGTCACCGGAGCAGATCTCCAATCGCCTCCGTCGGGATCATC
CCGACGACGAGAGCATGCAGGTGAGCCACGAAACGATCTACCAAGCCCTCTACTTCCAGGCGCGCGGTGGCCTCAAAAAG
GAAGTGCAGCAAGCACTTCGAACCGGGCGCACCCGACGCAAACCACACCGCAAAGAAGGCGAGCGCTATCAGCGCTTCAC
CGACCCGATGGTGATGATCAGCGACCGCCCAGCCGAGGTGGACGACCGTGCGGTTCCCGGGCATTGGGAAGGGGATTTGA
TCACCGGGGAGAAGAACCAGACCGCGATCGGCACTCTGGTCGAGCGATCGACGCGCTACACCATGCTGGTGCACCTGCCA
GGCGGGCACGACGCCGAATCGGTACGGGATGCGCTAATTGCGACTATCAGCACTCTTCCGGCGCATCTGCGTGGCTCACT
GACTTGGGACCAAGGCTGCGAGATGGCAGGGCACAAGCAGTTCACGATGGCCACCGATATGGCCGTGTACTTCTGCGATC
CGGCCAGTCCCTGGCAGCGCGGCAGCAACGAGAACACCAACGGCCTGCTGCGCCAGTACTTCCCCAAAGGCACCGACCTG
AGCATCTACGGCCCCGAGGACCTCGAACACGTCGCCCAGGAACTCAACGGCCGCCCACGCAAAACGCTCGGCTGGGATAC
CCCAGCCGAGCGCCTGCGTGATCTACTACTGACCAATTAA

Upstream 100 bases:

>100_bases
CCGCCTCGGAGTAATCAGTAGCACCGACGCAGACGGCCCCGGACATCAAGCGGGTTCACACGGTCGTCGCAACGCTCTCA
TTTGAGAGGTTGCGGCGACC

Downstream 100 bases:

>100_bases
CCAGCAGTGTTGCGACGACCCCTCGAAACCGCCATCAGTCCGGGGCCGCTCTGCGTTGTCACCGGTCGGTGTCTTTGCCG
GTCGACGCGGAGATTGTCGT

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 519; Mature: 518

Protein sequence:

>519_residues
MSFSEDCVRFGDRLARLVDAGVPVKEAAVATGVSRDRCYAILRAIGRPVGQARGRGERADQRGVADLGVVVAVFKDTGSI
LQAATACGVSHSTARKLLVAEGLVTSGKIPWGKPEAKRRCLELFEQGWSTGAAAREVGVNVRTARDWRKGIRHTNNTRVH
PDGRVVDYTDRTVYKQSVSNLICDDTGRPAIDDRYLSVQDRVAIADGLLGKESLRTIAGRIGKNVSTVSREIRARSIDGR
YLPYHADRAAASARARPKQSKLVVNVVLRGAVEEGLSRKLSPEQISNRLRRDHPDDESMQVSHETIYQALYFQARGGLKK
EVQQALRTGRTRRKPHRKEGERYQRFTDPMVMISDRPAEVDDRAVPGHWEGDLITGEKNQTAIGTLVERSTRYTMLVHLP
GGHDAESVRDALIATISTLPAHLRGSLTWDQGCEMAGHKQFTMATDMAVYFCDPASPWQRGSNENTNGLLRQYFPKGTDL
SIYGPEDLEHVAQELNGRPRKTLGWDTPAERLRDLLLTN

Sequences:

>Translated_519_residues
MSFSEDCVRFGDRLARLVDAGVPVKEAAVATGVSRDRCYAILRAIGRPVGQARGRGERADQRGVADLGVVVAVFKDTGSI
LQAATACGVSHSTARKLLVAEGLVTSGKIPWGKPEAKRRCLELFEQGWSTGAAAREVGVNVRTARDWRKGIRHTNNTRVH
PDGRVVDYTDRTVYKQSVSNLICDDTGRPAIDDRYLSVQDRVAIADGLLGKESLRTIAGRIGKNVSTVSREIRARSIDGR
YLPYHADRAAASARARPKQSKLVVNVVLRGAVEEGLSRKLSPEQISNRLRRDHPDDESMQVSHETIYQALYFQARGGLKK
EVQQALRTGRTRRKPHRKEGERYQRFTDPMVMISDRPAEVDDRAVPGHWEGDLITGEKNQTAIGTLVERSTRYTMLVHLP
GGHDAESVRDALIATISTLPAHLRGSLTWDQGCEMAGHKQFTMATDMAVYFCDPASPWQRGSNENTNGLLRQYFPKGTDL
SIYGPEDLEHVAQELNGRPRKTLGWDTPAERLRDLLLTN
>Mature_518_residues
SFSEDCVRFGDRLARLVDAGVPVKEAAVATGVSRDRCYAILRAIGRPVGQARGRGERADQRGVADLGVVVAVFKDTGSIL
QAATACGVSHSTARKLLVAEGLVTSGKIPWGKPEAKRRCLELFEQGWSTGAAAREVGVNVRTARDWRKGIRHTNNTRVHP
DGRVVDYTDRTVYKQSVSNLICDDTGRPAIDDRYLSVQDRVAIADGLLGKESLRTIAGRIGKNVSTVSREIRARSIDGRY
LPYHADRAAASARARPKQSKLVVNVVLRGAVEEGLSRKLSPEQISNRLRRDHPDDESMQVSHETIYQALYFQARGGLKKE
VQQALRTGRTRRKPHRKEGERYQRFTDPMVMISDRPAEVDDRAVPGHWEGDLITGEKNQTAIGTLVERSTRYTMLVHLPG
GHDAESVRDALIATISTLPAHLRGSLTWDQGCEMAGHKQFTMATDMAVYFCDPASPWQRGSNENTNGLLRQYFPKGTDLS
IYGPEDLEHVAQELNGRPRKTLGWDTPAERLRDLLLTN

Specific function: Required for the transposition of the insertion element (Potential) [H]

COG id: COG2826

COG function: function code L; Transposase and inactivated derivatives, IS30 family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Escherichia coli, GI1786450, Length=318, Percent_Identity=45.5974842767296, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1790736, Length=318, Percent_Identity=45.2830188679245, Blast_Score=255, Evalue=4e-69,
Organism=Escherichia coli, GI1787671, Length=318, Percent_Identity=45.2830188679245, Blast_Score=255, Evalue=4e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337
- InterPro:   IPR001598 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 57535; Mature: 57404

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS50994 INTEGRASE ; PS01043 TRANSPOSASE_IS30

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFSEDCVRFGDRLARLVDAGVPVKEAAVATGVSRDRCYAILRAIGRPVGQARGRGERAD
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHCCCHHHHCCCCCCHH
QRGVADLGVVVAVFKDTGSILQAATACGVSHSTARKLLVAEGLVTSGKIPWGKPEAKRRC
HCCHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHCCCCCCCCCHHHHHH
LELFEQGWSTGAAAREVGVNVRTARDWRKGIRHTNNTRVHPDGRVVDYTDRTVYKQSVSN
HHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHCCCCCCEECCCCCEEECCHHHHHHHHHHH
LICDDTGRPAIDDRYLSVQDRVAIADGLLGKESLRTIAGRIGKNVSTVSREIRARSIDGR
HHCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
YLPYHADRAAASARARPKQSKLVVNVVLRGAVEEGLSRKLSPEQISNRLRRDHPDDESMQ
CCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHH
VSHETIYQALYFQARGGLKKEVQQALRTGRTRRKPHRKEGERYQRFTDPMVMISDRPAEV
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCC
DDRAVPGHWEGDLITGEKNQTAIGTLVERSTRYTMLVHLPGGHDAESVRDALIATISTLP
CCCCCCCCCCCCEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHH
AHLRGSLTWDQGCEMAGHKQFTMATDMAVYFCDPASPWQRGSNENTNGLLRQYFPKGTDL
HHHCCCCCHHHCCCCCCCCCEEEEECEEEEEECCCCHHHCCCCCCCHHHHHHHCCCCCCE
SIYGPEDLEHVAQELNGRPRKTLGWDTPAERLRDLLLTN
EEECCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
SFSEDCVRFGDRLARLVDAGVPVKEAAVATGVSRDRCYAILRAIGRPVGQARGRGERAD
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHCCCHHHHCCCCCCHH
QRGVADLGVVVAVFKDTGSILQAATACGVSHSTARKLLVAEGLVTSGKIPWGKPEAKRRC
HCCHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHCCCCCCCCCHHHHHH
LELFEQGWSTGAAAREVGVNVRTARDWRKGIRHTNNTRVHPDGRVVDYTDRTVYKQSVSN
HHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHCCCCCCEECCCCCEEECCHHHHHHHHHHH
LICDDTGRPAIDDRYLSVQDRVAIADGLLGKESLRTIAGRIGKNVSTVSREIRARSIDGR
HHCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
YLPYHADRAAASARARPKQSKLVVNVVLRGAVEEGLSRKLSPEQISNRLRRDHPDDESMQ
CCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHH
VSHETIYQALYFQARGGLKKEVQQALRTGRTRRKPHRKEGERYQRFTDPMVMISDRPAEV
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCC
DDRAVPGHWEGDLITGEKNQTAIGTLVERSTRYTMLVHLPGGHDAESVRDALIATISTLP
CCCCCCCCCCCCEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHH
AHLRGSLTWDQGCEMAGHKQFTMATDMAVYFCDPASPWQRGSNENTNGLLRQYFPKGTDL
HHHCCCCCHHHCCCCCCCCCEEEEECEEEEEECCCCHHHCCCCCCCHHHHHHHCCCCCCE
SIYGPEDLEHVAQELNGRPRKTLGWDTPAERLRDLLLTN
EEECCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1334071 [H]