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The map label for this gene is qor [C]

Identifier: 119869841

GI number: 119869841

Start: 4024400

End: 4025377

Strand: Direct

Name: qor [C]

Synonym: Mkms_3810

Alternate gene names: 119869841

Gene position: 4024400-4025377 (Clockwise)

Preceding gene: 119869840

Following gene: 119869850

Centisome position: 70.15

GC content: 72.6

Gene sequence:

>978_bases
GTGAGAGCCGCGGTCTGCGCGGCCCCCGGACCGCCGGAGGGGGTGCGGATCGAGGAGCTGCCGTCCCCCGTGCCCGGACC
CGGTGAGGTACTGGTGCGGGTCGGCGCGGCGGCGGTGAACTTCCCCGACGTCCTGTTGATCGCGGGCCGCTATCAGGTCA
GCGTGCCCACACCATTCGTCCCGGGCAGCGAGTTCGCCGGCACCGTGATCGGGATCGGTCCGGGGACAGCGGGATTCGCG
GTGGGCGATCGGGTGACCGGAACCGGCATGCACGGTGCGTTCGCCGAGGAGGTGGCGGTCGCGGCCGACGCGCTGAACCC
GATCGCTGACGGTGTCGACGACCGGACGGCCGCCGCTTCCGGGGTGGCGCACCGCACGGCGTACCACACGCTGCGCTCGG
TGGCGCGGACCCAACCCGGCGACGAGGTGGTCGTCCTCGGCGCCGGCGGCGGGGTGGGCCTGGCGGCCGTGCAGCTCGCG
GCGCACCTCGGCGCCCGGGTCACCGCGGTGGCCTCGTCGGCCGAGAAGCTGGCCGCGGCAACGCAACACGGCGCGAACCG
GGTGATCAACCACCGTTCCGGCCCCCTGCGGGACGCCCTGCGCGACGCGGTGCCCGGCGGTGCGGCGGCGGTGGTCGACC
CGGTCGGGGGCGAACTGTCCGAACCTGCCCTGCGTTCACTGCGCCGGGGTGGGCGCTTCGTCACCGTCGGCTTCGCCTCC
GGCGTCATCCCCCGGATTCCGCTGAACCTGGTGCTGATCAAGGGCGTGACGGTGCAGGGCTTCCAGTTCGGCGACATCCC
CGCCGACGAATTCGAACGTAACGAGCGGGAACTACGGAAGTTGCTCGCCGACAGCATGATTCGTCCGCACATCGGTGAGG
TCTACGCACTCGAAGACGTCACCGCCGCGCTGCGGCAGGTGGCCGACGGACGTGCCGTCGGCAAAGTGGTGATCGACCTC
TCCGGGCGCGGAGGCTAG

Upstream 100 bases:

>100_bases
TCCAGCGCGCCGGCGACGACGAGAAGCTGCTGGCCTTCGGCCCGGTGGTGACCGATCTGATGGCCTCGGCCGCCGAACTC
GCCGAATCCAGCGACTACCG

Downstream 100 bases:

>100_bases
CTCGCCGGGATGAGGTCCGCGGCCACCGACGGGCGGGCCATCATGCCGCAGCGGAAGGTCTCGATCTGACCGACGAACGC
GGCCTCGATGTCGTTGACCG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: Acryloyl-CoA reductase [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MRAAVCAAPGPPEGVRIEELPSPVPGPGEVLVRVGAAAVNFPDVLLIAGRYQVSVPTPFVPGSEFAGTVIGIGPGTAGFA
VGDRVTGTGMHGAFAEEVAVAADALNPIADGVDDRTAAASGVAHRTAYHTLRSVARTQPGDEVVVLGAGGGVGLAAVQLA
AHLGARVTAVASSAEKLAAATQHGANRVINHRSGPLRDALRDAVPGGAAAVVDPVGGELSEPALRSLRRGGRFVTVGFAS
GVIPRIPLNLVLIKGVTVQGFQFGDIPADEFERNERELRKLLADSMIRPHIGEVYALEDVTAALRQVADGRAVGKVVIDL
SGRGG

Sequences:

>Translated_325_residues
MRAAVCAAPGPPEGVRIEELPSPVPGPGEVLVRVGAAAVNFPDVLLIAGRYQVSVPTPFVPGSEFAGTVIGIGPGTAGFA
VGDRVTGTGMHGAFAEEVAVAADALNPIADGVDDRTAAASGVAHRTAYHTLRSVARTQPGDEVVVLGAGGGVGLAAVQLA
AHLGARVTAVASSAEKLAAATQHGANRVINHRSGPLRDALRDAVPGGAAAVVDPVGGELSEPALRSLRRGGRFVTVGFAS
GVIPRIPLNLVLIKGVTVQGFQFGDIPADEFERNERELRKLLADSMIRPHIGEVYALEDVTAALRQVADGRAVGKVVIDL
SGRGG
>Mature_325_residues
MRAAVCAAPGPPEGVRIEELPSPVPGPGEVLVRVGAAAVNFPDVLLIAGRYQVSVPTPFVPGSEFAGTVIGIGPGTAGFA
VGDRVTGTGMHGAFAEEVAVAADALNPIADGVDDRTAAASGVAHRTAYHTLRSVARTQPGDEVVVLGAGGGVGLAAVQLA
AHLGARVTAVASSAEKLAAATQHGANRVINHRSGPLRDALRDAVPGGAAAVVDPVGGELSEPALRSLRRGGRFVTVGFAS
GVIPRIPLNLVLIKGVTVQGFQFGDIPADEFERNERELRKLLADSMIRPHIGEVYALEDVTAALRQVADGRAVGKVVIDL
SGRGG

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the acryloyl- CoA dependent NADPH oxidation and formation of propionyl-CoA. Inactive towards 3-hydroxypropionyl-CoA, NADH and crotonyl-CoA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=324, Percent_Identity=29.9382716049383, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI13236495, Length=324, Percent_Identity=29.9382716049383, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI18379349, Length=309, Percent_Identity=30.7443365695793, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI22538446, Length=337, Percent_Identity=28.486646884273, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI22538444, Length=337, Percent_Identity=28.486646884273, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI28557745, Length=335, Percent_Identity=30.1492537313433, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI194239676, Length=323, Percent_Identity=27.8637770897833, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI24308257, Length=353, Percent_Identity=25.7790368271955, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI67078404, Length=291, Percent_Identity=29.8969072164948, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI67078406, Length=284, Percent_Identity=29.9295774647887, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI41872631, Length=310, Percent_Identity=28.0645161290323, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI47519420, Length=363, Percent_Identity=26.7217630853994, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI197927207, Length=192, Percent_Identity=30.2083333333333, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1790485, Length=313, Percent_Identity=30.9904153354633, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1790045, Length=346, Percent_Identity=26.5895953757225, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789651, Length=266, Percent_Identity=30.8270676691729, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI226510941, Length=330, Percent_Identity=25.1515151515152, Blast_Score=75, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17507255, Length=321, Percent_Identity=29.9065420560748, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17536829, Length=307, Percent_Identity=28.6644951140065, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562584, Length=347, Percent_Identity=27.6657060518732, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17556000, Length=321, Percent_Identity=25.2336448598131, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319520, Length=313, Percent_Identity=30.0319488817891, Blast_Score=122, Evalue=9e-29,
Organism=Saccharomyces cerevisiae, GI6323729, Length=340, Percent_Identity=24.4117647058824, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323961, Length=334, Percent_Identity=24.5508982035928, Blast_Score=76, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6319621, Length=340, Percent_Identity=25, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324486, Length=337, Percent_Identity=25.2225519287834, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45550423, Length=276, Percent_Identity=27.536231884058, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.3.1.84 [H]

Molecular weight: Translated: 33010; Mature: 33010

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAAVCAAPGPPEGVRIEELPSPVPGPGEVLVRVGAAAVNFPDVLLIAGRYQVSVPTPFV
CCCEEECCCCCCCCCCHHHCCCCCCCCHHHHEEECHHHCCCCCEEEEECEEEEECCCCCC
PGSEFAGTVIGIGPGTAGFAVGDRVTGTGMHGAFAEEVAVAADALNPIADGVDDRTAAAS
CCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHH
GVAHRTAYHTLRSVARTQPGDEVVVLGAGGGVGLAAVQLAAHLGARVTAVASSAEKLAAA
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
TQHGANRVINHRSGPLRDALRDAVPGGAAAVVDPVGGELSEPALRSLRRGGRFVTVGFAS
HHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHCCCEEEEECCC
GVIPRIPLNLVLIKGVTVQGFQFGDIPADEFERNERELRKLLADSMIRPHIGEVYALEDV
CCCCCCCEEEEEEECCEEECEEECCCCHHHHHCCHHHHHHHHHHHHCCCCCCCEEEHHHH
TAALRQVADGRAVGKVVIDLSGRGG
HHHHHHHHCCCEEEEEEEEECCCCC
>Mature Secondary Structure
MRAAVCAAPGPPEGVRIEELPSPVPGPGEVLVRVGAAAVNFPDVLLIAGRYQVSVPTPFV
CCCEEECCCCCCCCCCHHHCCCCCCCCHHHHEEECHHHCCCCCEEEEECEEEEECCCCCC
PGSEFAGTVIGIGPGTAGFAVGDRVTGTGMHGAFAEEVAVAADALNPIADGVDDRTAAAS
CCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHH
GVAHRTAYHTLRSVARTQPGDEVVVLGAGGGVGLAAVQLAAHLGARVTAVASSAEKLAAA
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
TQHGANRVINHRSGPLRDALRDAVPGGAAAVVDPVGGELSEPALRSLRRGGRFVTVGFAS
HHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHCCCEEEEECCC
GVIPRIPLNLVLIKGVTVQGFQFGDIPADEFERNERELRKLLADSMIRPHIGEVYALEDV
CCCCCCCEEEEEEECCEEECEEECCCCHHHHHCCHHHHHHHHHHHHCCCCCCCEEEHHHH
TAALRQVADGRAVGKVVIDLSGRGG
HHHHHHHHCCCEEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]