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The map label for this gene is norD [H]

Identifier: 119869831

GI number: 119869831

Start: 4014151

End: 4015863

Strand: Direct

Name: norD [H]

Synonym: Mkms_3800

Alternate gene names: 119869831

Gene position: 4014151-4015863 (Clockwise)

Preceding gene: 119869830

Following gene: 119869833

Centisome position: 69.97

GC content: 67.66

Gene sequence:

>1713_bases
GTGACCGACGCCTCCACCCCGGGGAACCCAGACCGGTTCCGGTTCCTCGCCACCTACATCGCCGGCAGGTCGGTCGATGT
CACCGAGGCAGCGGACGGCCAACCCGTGCACACCGACGGCCAGTTCATCTTCGTCTCGGCCGGAGGTTCGATCGAGCAGC
AACGCCGCGAGATGATGGTCCAGGCCGCACTTCTCGGTGCGGGCAGCCTCGATCCGCGATTGGTGAAGGGACTCCGGGCT
CGGGCCACGACGGCGCGCCGTTACCTGACGCTCGAAGGACAGCGCGCTCTCGCCCAACTCGCGCAACGGATTCCGCTCGA
TGCCGCGCTGCTGGCCGACGGCCGACCCGCCACTGCGACCGCCGAAGAGTCGCTCGAGGTGGCCAAGAGCCGAGCCAAGG
TCGCCGACCCCCCGGAATGGTTCGGCGTCATCAAACCCTCCCGGCTGATGGCGGCTCCCGCCGGACCGGGTGGACAGGCC
ACCAACAAAGACCTCAAACTGCAGTTCGACCCCATCGACATGCCCGAGTCGGATGACGACGACGAGGACCAGGACGATGA
CGGCGGGAAGTCCGGGGACAGCAAGATCCTCAAGCTGTTCGAGAGTCCGATCTTCAACAACCAGTCGATGTCGGACTACA
TGCGAAAGATGTTCGGCGGTAAGCGTTCCGAAGGGGAGGGTGCCGCGGGCGCGGAGATGACAGTTCGCTCCACACGGCGA
GTACAGGAGATCGGCGCGAATGCCCGTCCCCTGCCCACCCGGATCCAGTTCACCGACGACGGCAAACCCGGTGCGGCGTT
GGGCGTGGGAGGCGCCCTCTATCCGGAATGGGACGTCTTCAACGACCGGTACAAGCCGGACTGGTGCCGGGTGATCAACT
TCCCATTGACGGTCGCCGCCGACGTCTCGGATGCCGGTGTCGCGCACGACGACGTGTTGCGGCGCCGCCTGGCTCGCGTC
GGGCTCGGCCCAAAGGTGCTGCGCGGCCGCGCCGACGGCGACGACCTCGACATCGAGGCGCTCATCGACCTGTTCGTCGA
CCTGCAGTCCGGCTTCTCCGGTGCCGAACACGTTTATCTGGAGCGCCGTAAACTCGCCCGCAATCTCGGCGTGCTGATCC
TCATCGACGCGTCCGGGTCGGCCGTCGACGCCGATACGGACGGCCTCGCGGTGCACGACCACCAGCGACGGGCGGCCGCC
ACCTTGGCCGTCACCCTCGAGGAGCTCGGTGACCGCGTCGCCGTCTACGCATTCCGGTCACAGGGCCGGCACGCTGTGCA
TCTGCCGGCCATCAAGACGTTCGACCAGAGTTTCGGCGCCGTCGGGCGGGCCCGGCTCAACCAGCTCGAGCCGGCGAGCT
ACACCCGCCTCGGGGCCGGAATCCGGGGTGCGGGCGAGGTTCTCAAGAACGAGGCCGGCACACCGAACCGACTGCTGCTG
GTCCTCTCGGACGGATTTCCCTACGACGACGGCTACGAGGGCCGCTACGCGGAAGCCGACGCGCACAAGGCTCTCGAAGA
GCTCCGCACCGAGGGCGTCGCCTGCCTGTGCCTGTCCATCGGCGCCGCCACGGAAACCGATGTGCTCGAACGCGTCTTCG
GTTCCGCCAGCTTCGCCAGCGCCGCAGATCTCTCCGAGTTGAGCCCCCAGATGGACGAGTTGTTCATGTCCGCGCTCGCC
GAACTCGCCGCGCCGAAACCCGCGCGGGTGTGA

Upstream 100 bases:

>100_bases
AGGTGCTCTCCGACGATGAGGACGTCATCCGCGCCCTCGACGAACTCGTCGACACGGTCCTGCCCCGGAGCCGCGGCGGC
GGCGACATTCGACCCGAGAC

Downstream 100 bases:

>100_bases
CCGGTCGGCCCGTCATCCGTCGAGCGATTCCCAGAACCGGGTGAGGGCCGCGGCACCGGCGGTGGGGTCCTCCACCATCC
ACCAGTGTCCCAGCCCGTCG

Product: von Willebrand factor, type A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 570; Mature: 569

Protein sequence:

>570_residues
MTDASTPGNPDRFRFLATYIAGRSVDVTEAADGQPVHTDGQFIFVSAGGSIEQQRREMMVQAALLGAGSLDPRLVKGLRA
RATTARRYLTLEGQRALAQLAQRIPLDAALLADGRPATATAEESLEVAKSRAKVADPPEWFGVIKPSRLMAAPAGPGGQA
TNKDLKLQFDPIDMPESDDDDEDQDDDGGKSGDSKILKLFESPIFNNQSMSDYMRKMFGGKRSEGEGAAGAEMTVRSTRR
VQEIGANARPLPTRIQFTDDGKPGAALGVGGALYPEWDVFNDRYKPDWCRVINFPLTVAADVSDAGVAHDDVLRRRLARV
GLGPKVLRGRADGDDLDIEALIDLFVDLQSGFSGAEHVYLERRKLARNLGVLILIDASGSAVDADTDGLAVHDHQRRAAA
TLAVTLEELGDRVAVYAFRSQGRHAVHLPAIKTFDQSFGAVGRARLNQLEPASYTRLGAGIRGAGEVLKNEAGTPNRLLL
VLSDGFPYDDGYEGRYAEADAHKALEELRTEGVACLCLSIGAATETDVLERVFGSASFASAADLSELSPQMDELFMSALA
ELAAPKPARV

Sequences:

>Translated_570_residues
MTDASTPGNPDRFRFLATYIAGRSVDVTEAADGQPVHTDGQFIFVSAGGSIEQQRREMMVQAALLGAGSLDPRLVKGLRA
RATTARRYLTLEGQRALAQLAQRIPLDAALLADGRPATATAEESLEVAKSRAKVADPPEWFGVIKPSRLMAAPAGPGGQA
TNKDLKLQFDPIDMPESDDDDEDQDDDGGKSGDSKILKLFESPIFNNQSMSDYMRKMFGGKRSEGEGAAGAEMTVRSTRR
VQEIGANARPLPTRIQFTDDGKPGAALGVGGALYPEWDVFNDRYKPDWCRVINFPLTVAADVSDAGVAHDDVLRRRLARV
GLGPKVLRGRADGDDLDIEALIDLFVDLQSGFSGAEHVYLERRKLARNLGVLILIDASGSAVDADTDGLAVHDHQRRAAA
TLAVTLEELGDRVAVYAFRSQGRHAVHLPAIKTFDQSFGAVGRARLNQLEPASYTRLGAGIRGAGEVLKNEAGTPNRLLL
VLSDGFPYDDGYEGRYAEADAHKALEELRTEGVACLCLSIGAATETDVLERVFGSASFASAADLSELSPQMDELFMSALA
ELAAPKPARV
>Mature_569_residues
TDASTPGNPDRFRFLATYIAGRSVDVTEAADGQPVHTDGQFIFVSAGGSIEQQRREMMVQAALLGAGSLDPRLVKGLRAR
ATTARRYLTLEGQRALAQLAQRIPLDAALLADGRPATATAEESLEVAKSRAKVADPPEWFGVIKPSRLMAAPAGPGGQAT
NKDLKLQFDPIDMPESDDDDEDQDDDGGKSGDSKILKLFESPIFNNQSMSDYMRKMFGGKRSEGEGAAGAEMTVRSTRRV
QEIGANARPLPTRIQFTDDGKPGAALGVGGALYPEWDVFNDRYKPDWCRVINFPLTVAADVSDAGVAHDDVLRRRLARVG
LGPKVLRGRADGDDLDIEALIDLFVDLQSGFSGAEHVYLERRKLARNLGVLILIDASGSAVDADTDGLAVHDHQRRAAAT
LAVTLEELGDRVAVYAFRSQGRHAVHLPAIKTFDQSFGAVGRARLNQLEPASYTRLGAGIRGAGEVLKNEAGTPNRLLLV
LSDGFPYDDGYEGRYAEADAHKALEELRTEGVACLCLSIGAATETDVLERVFGSASFASAADLSELSPQMDELFMSALAE
LAAPKPARV

Specific function: Part of the operon norEFCBQD encoding nitric oxide reductase. Essential virulence factor, probably involved in the detoxification of nitric oxide (NO) produced in the macrophages during the innate response against infection [H]

COG id: COG4548

COG function: function code P; Nitric oxide reductase activation protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 VWFA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002035 [H]

Pfam domain/function: PF00092 VWA [H]

EC number: NA

Molecular weight: Translated: 61177; Mature: 61046

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50234 VWFA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDASTPGNPDRFRFLATYIAGRSVDVTEAADGQPVHTDGQFIFVSAGGSIEQQRREMMV
CCCCCCCCCHHHHHHHHHHHCCCCCEECCCCCCCEEECCCCEEEEECCCCHHHHHHHHHH
QAALLGAGSLDPRLVKGLRARATTARRYLTLEGQRALAQLAQRIPLDAALLADGRPATAT
HHHHHCCCCCCHHHHHHHHHHHHHHHHEEEECHHHHHHHHHHHCCCCEEEECCCCCCCCC
AEESLEVAKSRAKVADPPEWFGVIKPSRLMAAPAGPGGQATNKDLKLQFDPIDMPESDDD
HHHHHHHHHHHCCCCCCHHHHCCCCCCCEEECCCCCCCCCCCCCEEEEECCCCCCCCCCC
DEDQDDDGGKSGDSKILKLFESPIFNNQSMSDYMRKMFGGKRSEGEGAAGAEMTVRSTRR
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
VQEIGANARPLPTRIQFTDDGKPGAALGVGGALYPEWDVFNDRYKPDWCRVINFPLTVAA
HHHHCCCCCCCCCEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCHHEEEECCEEEEE
DVSDAGVAHDDVLRRRLARVGLGPKVLRGRADGDDLDIEALIDLFVDLQSGFSGAEHVYL
CCCCCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHH
ERRKLARNLGVLILIDASGSAVDADTDGLAVHDHQRRAAATLAVTLEELGDRVAVYAFRS
HHHHHHHCCCEEEEEECCCCEECCCCCCCEECCHHHHHHHHHHHHHHHHCCEEEEEEECC
QGRHAVHLPAIKTFDQSFGAVGRARLNQLEPASYTRLGAGIRGAGEVLKNEAGTPNRLLL
CCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHCCCCCCCEEEE
VLSDGFPYDDGYEGRYAEADAHKALEELRTEGVACLCLSIGAATETDVLERVFGSASFAS
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHCCCCHHH
AADLSELSPQMDELFMSALAELAAPKPARV
HHHHHHCCHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TDASTPGNPDRFRFLATYIAGRSVDVTEAADGQPVHTDGQFIFVSAGGSIEQQRREMMV
CCCCCCCCHHHHHHHHHHHCCCCCEECCCCCCCEEECCCCEEEEECCCCHHHHHHHHHH
QAALLGAGSLDPRLVKGLRARATTARRYLTLEGQRALAQLAQRIPLDAALLADGRPATAT
HHHHHCCCCCCHHHHHHHHHHHHHHHHEEEECHHHHHHHHHHHCCCCEEEECCCCCCCCC
AEESLEVAKSRAKVADPPEWFGVIKPSRLMAAPAGPGGQATNKDLKLQFDPIDMPESDDD
HHHHHHHHHHHCCCCCCHHHHCCCCCCCEEECCCCCCCCCCCCCEEEEECCCCCCCCCCC
DEDQDDDGGKSGDSKILKLFESPIFNNQSMSDYMRKMFGGKRSEGEGAAGAEMTVRSTRR
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
VQEIGANARPLPTRIQFTDDGKPGAALGVGGALYPEWDVFNDRYKPDWCRVINFPLTVAA
HHHHCCCCCCCCCEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCHHEEEECCEEEEE
DVSDAGVAHDDVLRRRLARVGLGPKVLRGRADGDDLDIEALIDLFVDLQSGFSGAEHVYL
CCCCCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHH
ERRKLARNLGVLILIDASGSAVDADTDGLAVHDHQRRAAATLAVTLEELGDRVAVYAFRS
HHHHHHHCCCEEEEEECCCCEECCCCCCCEECCHHHHHHHHHHHHHHHHCCEEEEEEECC
QGRHAVHLPAIKTFDQSFGAVGRARLNQLEPASYTRLGAGIRGAGEVLKNEAGTPNRLLL
CCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHCCCCCCCEEEE
VLSDGFPYDDGYEGRYAEADAHKALEELRTEGVACLCLSIGAATETDVLERVFGSASFAS
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHCCCCHHH
AADLSELSPQMDELFMSALAELAAPKPARV
HHHHHHCCHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA