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The map label for this gene is 119869765

Identifier: 119869765

GI number: 119869765

Start: 3951953

End: 3953095

Strand: Direct

Name: 119869765

Synonym: Mkms_3733

Alternate gene names: NA

Gene position: 3951953-3953095 (Clockwise)

Preceding gene: 119869764

Following gene: 119869766

Centisome position: 68.88

GC content: 66.58

Gene sequence:

>1143_bases
ATGAACGACGTAGCCATCATCGGCGTCGGCCTGCATCCCTTCGGCCGGTTCGACAAGACCGCGATGGAGATGGGCGCCGA
GGCGATCCAGTTCGCGCTGGCCGACGCGAAACTGGAGTGGAAGGACATTCAGTTCGGCTTCGGCGGCAGCTACGAGGTGT
CCAACCCCGATGCCGTCACCCGGCTGGTCGGCCTCACCGGAATCACGTTCACCAACGTGTTCAACGCCTGCGCCACGGCG
GCCAGCGCGATCCAGCAGACCGCTGACACGATCCGCCTGGGCAAGTACGACATCGGCATCGCCATCGGACTCGACAAACA
CCCCCGCGGTGCGTTCACCGACGATCCGGCCAAACTCGCCCTGCCACAGTGGTATGCCGAGAACGGTCAGTTCGTCACCA
CGAAGTTCTTCGGCATGAAGGCCAATCACTACCTCCACAAGCACGGCATCTCCGAGGAGACGCTGGCGCGGGTGGCCAAC
AAGAACTTCCGCAACGGCGAACGGAATCCGAATGCGTTCCGCCGCAAGGAGATCTCGGTCGACGAGATCATGGCGTCACC
GGTTCTGAACTACCCGTTGCGGCAGTACATGTTCTGCGCACCCGACGAGGGCGCCGCCGCGGTGATCATGTGCCGCGGTG
ACATCGCCCACCGCTACACCGACAAGCCGGTATTCCTGCGCGCCAGCGAGATCCGCACACGGACGTTCGGCGCCTACGAG
GTGCACGCCACCTCGGCGCCGCTGGACGAGGACGCCTCCCCCACCGTCTACGCCGCGCGCGCCGCCTACGAGATCGCCGG
AATCGGACCCGAGGATGTCGACATCGCCCAGCTGCAGGACACCGACGCCGGCGCGGAGGTCATCCACATGGCCGAGACCG
GATTGTGCGCCGACGGTGAGCAGGAGAAGTTGCTCGCCGACGGGGCCACCGAGATCGGTGGCAGCATCCCGGTCAACACC
GACGGCGGCCTGATCGCCAACGGGGAGCCCATCGGCGCATCCGGTCTGCGCCAGGTGCACGAACTCGTCCGCCAACTGCG
CGGGGAGGCCGGCGACCGCCAGGTACCCGGCGAGCCGAAAGTCGGTCTGGCACAGGTGTACGGCGCGCCCGGCACCGCCT
CGGCGACCATCCTGACGGTCTGA

Upstream 100 bases:

>100_bases
GAGCTGACCATGATTCCGTTCACCAAGGACGAGGACGGCGAGGACATCGTCACATTCGCCTTCCAACCGGTCTGAGGCCG
ACGAGAGGAACAGTCGAGAT

Downstream 100 bases:

>100_bases
CGTCGGTGACGAATCGGAACCCGGCGCGAGACTATCGTTCTAGGATTCGCAAATGAAGCTTTCGCAGACGAACGGGCGGA
CGCGGCGGTCCGTTTTGCCG

Product: thiolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MNDVAIIGVGLHPFGRFDKTAMEMGAEAIQFALADAKLEWKDIQFGFGGSYEVSNPDAVTRLVGLTGITFTNVFNACATA
ASAIQQTADTIRLGKYDIGIAIGLDKHPRGAFTDDPAKLALPQWYAENGQFVTTKFFGMKANHYLHKHGISEETLARVAN
KNFRNGERNPNAFRRKEISVDEIMASPVLNYPLRQYMFCAPDEGAAAVIMCRGDIAHRYTDKPVFLRASEIRTRTFGAYE
VHATSAPLDEDASPTVYAARAAYEIAGIGPEDVDIAQLQDTDAGAEVIHMAETGLCADGEQEKLLADGATEIGGSIPVNT
DGGLIANGEPIGASGLRQVHELVRQLRGEAGDRQVPGEPKVGLAQVYGAPGTASATILTV

Sequences:

>Translated_380_residues
MNDVAIIGVGLHPFGRFDKTAMEMGAEAIQFALADAKLEWKDIQFGFGGSYEVSNPDAVTRLVGLTGITFTNVFNACATA
ASAIQQTADTIRLGKYDIGIAIGLDKHPRGAFTDDPAKLALPQWYAENGQFVTTKFFGMKANHYLHKHGISEETLARVAN
KNFRNGERNPNAFRRKEISVDEIMASPVLNYPLRQYMFCAPDEGAAAVIMCRGDIAHRYTDKPVFLRASEIRTRTFGAYE
VHATSAPLDEDASPTVYAARAAYEIAGIGPEDVDIAQLQDTDAGAEVIHMAETGLCADGEQEKLLADGATEIGGSIPVNT
DGGLIANGEPIGASGLRQVHELVRQLRGEAGDRQVPGEPKVGLAQVYGAPGTASATILTV
>Mature_380_residues
MNDVAIIGVGLHPFGRFDKTAMEMGAEAIQFALADAKLEWKDIQFGFGGSYEVSNPDAVTRLVGLTGITFTNVFNACATA
ASAIQQTADTIRLGKYDIGIAIGLDKHPRGAFTDDPAKLALPQWYAENGQFVTTKFFGMKANHYLHKHGISEETLARVAN
KNFRNGERNPNAFRRKEISVDEIMASPVLNYPLRQYMFCAPDEGAAAVIMCRGDIAHRYTDKPVFLRASEIRTRTFGAYE
VHATSAPLDEDASPTVYAARAAYEIAGIGPEDVDIAQLQDTDAGAEVIHMAETGLCADGEQEKLLADGATEIGGSIPVNT
DGGLIANGEPIGASGLRQVHELVRQLRGEAGDRQVPGEPKVGLAQVYGAPGTASATILTV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=398, Percent_Identity=30.9045226130653, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI302344760, Length=332, Percent_Identity=32.5301204819277, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI302344767, Length=325, Percent_Identity=32.6153846153846, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI302344762, Length=308, Percent_Identity=31.8181818181818, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI55956775, Length=266, Percent_Identity=28.5714285714286, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17537653, Length=391, Percent_Identity=28.6445012787724, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24585051, Length=372, Percent_Identity=29.3010752688172, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI19921506, Length=372, Percent_Identity=28.7634408602151, Blast_Score=140, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: NA

Molecular weight: Translated: 40686; Mature: 40686

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDVAIIGVGLHPFGRFDKTAMEMGAEAIQFALADAKLEWKDIQFGFGGSYEVSNPDAVT
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCCHHHHH
RLVGLTGITFTNVFNACATAASAIQQTADTIRLGKYDIGIAIGLDKHPRGAFTDDPAKLA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEECCEEEEEEEECCCCCCCCCCCCCHHHC
LPQWYAENGQFVTTKFFGMKANHYLHKHGISEETLARVANKNFRNGERNPNAFRRKEISV
CCHHHCCCCCEEEEEEECCCCCCHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHCCCH
DEIMASPVLNYPLRQYMFCAPDEGAAAVIMCRGDIAHRYTDKPVFLRASEIRTRTFGAYE
HHHHHHHHHCCCHHHCEEECCCCCCEEEEEECCCHHHHCCCCCEEEEHHHHHHEECCEEE
VHATSAPLDEDASPTVYAARAAYEIAGIGPEDVDIAQLQDTDAGAEVIHMAETGLCADGE
EEECCCCCCCCCCCCEEEEEHEEEEECCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCC
QEKLLADGATEIGGSIPVNTDGGLIANGEPIGASGLRQVHELVRQLRGEAGDRQVPGEPK
HHHHHHCCHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
VGLAQVYGAPGTASATILTV
CCCEEEECCCCCCCEEEEEC
>Mature Secondary Structure
MNDVAIIGVGLHPFGRFDKTAMEMGAEAIQFALADAKLEWKDIQFGFGGSYEVSNPDAVT
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCCHHHHH
RLVGLTGITFTNVFNACATAASAIQQTADTIRLGKYDIGIAIGLDKHPRGAFTDDPAKLA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEECCEEEEEEEECCCCCCCCCCCCCHHHC
LPQWYAENGQFVTTKFFGMKANHYLHKHGISEETLARVANKNFRNGERNPNAFRRKEISV
CCHHHCCCCCEEEEEEECCCCCCHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHCCCH
DEIMASPVLNYPLRQYMFCAPDEGAAAVIMCRGDIAHRYTDKPVFLRASEIRTRTFGAYE
HHHHHHHHHCCCHHHCEEECCCCCCEEEEEECCCHHHHCCCCCEEEEHHHHHHEECCEEE
VHATSAPLDEDASPTVYAARAAYEIAGIGPEDVDIAQLQDTDAGAEVIHMAETGLCADGE
EEECCCCCCCCCCCCEEEEEHEEEEECCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCC
QEKLLADGATEIGGSIPVNTDGGLIANGEPIGASGLRQVHELVRQLRGEAGDRQVPGEPK
HHHHHHCCHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
VGLAQVYGAPGTASATILTV
CCCEEEECCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]