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The map label for this gene is malL [H]

Identifier: 119869716

GI number: 119869716

Start: 3883074

End: 3884693

Strand: Direct

Name: malL [H]

Synonym: Mkms_3684

Alternate gene names: 119869716

Gene position: 3883074-3884693 (Clockwise)

Preceding gene: 119869715

Following gene: 119869727

Centisome position: 67.68

GC content: 70.43

Gene sequence:

>1620_bases
ATGGGCGCAATGGCTCACCCCCCGACAGCTGACCAGCCCTGGTGGTCGCGCGCGGTGTTCTACCAGGTCTATCCCCGGTC
CTTCCACGACAGCGACGGCGACGGTGTCGGCGACCTCGACGGCGTGACCGCCAAACTCGACTATCTGAGTGAACTCGGCG
TCGACGCACTGTGGCTCAACCCGGTCACCGTCTCCCCCATGGCCGACCACGGCTACGACGTCGCCGACCCCCGCGACATC
GACCCGCTGTTCGGCGGCATCGACGCCCTGGACCGGCTCATCGCCGCCGCGCACGACCGCGGTATCCGCATCACCATGGA
TCTGGTGCCCAACCACACCAGCTCGGCGCACCCGTGGTTCCAGGCGGCGCTGGCGGCGGGTCCGGGCAGCGCCCAGCGGG
AGCGCTACATCTTCCGGGAGGGCACCGGTCCCGACGGGCTGCTCCCGCCCAACAACTGGATCTCCGTCTTCGGCGGGCCC
GCGTGGACGCGGATCGTCGAACCCGACGGGCAGCCCGGCCAGTGGTACCTGCACCTGTTCGACCCGGAGCAGCCCGACCT
CAACTGGGACAACCCCGAGGTCTTCGAGGATCTCGAGAAGACGCTGCGCTTCTGGCTCGACCGCGGCGTCGACGGTTTCC
GGATCGACGTGGCGCATGGGATGGCCAAACCGCCGGACCTGCCCGATATGGAGATCGCCGAGAACAGGATGCTCGCCGAG
ACCGCCAGCGATCCGCGGTTCGACCACCAGGGCGTCCACGACATCCACCGCAACATCCGCTCCGTGCTCGACGACTATCC
CGGCGCGGTCGCCGTCGGCGAGGTGTGGGTCTACGACAACGCCGCGTTCGCCGCCTACCTGCGGGCCGACGAACTGCATC
TGGGCTTCAACTTCCGGCTGGTGCGCGCCGACTTCGACGCCGACGAGATCCACGACGCGATCGAGAACTCGCTGGCCGCC
GTCGCCCTGGAAAACGCGACGCCGACGTGGACGCTGTCCAACCACGACGTCGAGCGGGAGGTCACCCGGTACGGCGGCGG
GGCGCTCGGGCTGGCGCGGGCCCGGGCGATGGCCCTGGTGATGCTGGCGCTGCCCGGCGTGGTGTTCGTCTACAACGGCG
AAGAACTCGGCCTGCCCAACGTCGACCTGCCCGACGAAGTGCTCCAGGACCCGGTGTGGGAACGCTCCGACCGCACCGAA
CGCGGGCGCGACGGATGCCGCGTGCCGATGCCGTGGAGCGGTGACGCTCCCCCGTTCGGGTTCTCGACGACGGCCGACAC
CTGGCTGCCGATGCCGGCGGAATGGTCGTCGCTGACCGTCGAACGCCAGCTGGCCGAGCCGGACTCCATGCTGCACTTCT
TCCGCCGGGCGCTGCGCCTGCGCCGGGACCGCTGTGGCGTCGACGGGGCCACGCTGACGCAGCTGTCCGCCGAGGACGGG
GTGGTCACGTTCCGCACCGACGGCGGACTCACCTGCGTGCTCAACGCCGGTGAGCGCCCGGTCGACCTGCCCCCCGGTGA
GGTGCTGCTCGCCAGCGCGCCCCTTCAGGCACATTCCCCGTCGCTTCGCTCGCCCCAGGATCGGCGGCTACCCCCCGACA
CGGCCGCCTGGGTGGTCTAA

Upstream 100 bases:

>100_bases
GGTGACGCTGGACGACGAGCACCGTAGGGAGCTGCTGGCCTACCTCGAGATGGCCGCGCAGTCGATGGTCAATTCGCCGT
TCTGAGCGCGGGCGGCCACA

Downstream 100 bases:

>100_bases
CGCAACACGACCGCCGGGTCGCCGCGCCGCCGCAGCACCGAACCGAACGGCGCGTCGATCCGCAGCCAGGTGGGCGAGAC
GCGGATCCGCACGATGTCGC

Product: alpha amylase catalytic subunit

Products: NA

Alternate protein names: Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase; Sucrase-isomaltase; Isomaltase [H]

Number of amino acids: Translated: 539; Mature: 538

Protein sequence:

>539_residues
MGAMAHPPTADQPWWSRAVFYQVYPRSFHDSDGDGVGDLDGVTAKLDYLSELGVDALWLNPVTVSPMADHGYDVADPRDI
DPLFGGIDALDRLIAAAHDRGIRITMDLVPNHTSSAHPWFQAALAAGPGSAQRERYIFREGTGPDGLLPPNNWISVFGGP
AWTRIVEPDGQPGQWYLHLFDPEQPDLNWDNPEVFEDLEKTLRFWLDRGVDGFRIDVAHGMAKPPDLPDMEIAENRMLAE
TASDPRFDHQGVHDIHRNIRSVLDDYPGAVAVGEVWVYDNAAFAAYLRADELHLGFNFRLVRADFDADEIHDAIENSLAA
VALENATPTWTLSNHDVEREVTRYGGGALGLARARAMALVMLALPGVVFVYNGEELGLPNVDLPDEVLQDPVWERSDRTE
RGRDGCRVPMPWSGDAPPFGFSTTADTWLPMPAEWSSLTVERQLAEPDSMLHFFRRALRLRRDRCGVDGATLTQLSAEDG
VVTFRTDGGLTCVLNAGERPVDLPPGEVLLASAPLQAHSPSLRSPQDRRLPPDTAAWVV

Sequences:

>Translated_539_residues
MGAMAHPPTADQPWWSRAVFYQVYPRSFHDSDGDGVGDLDGVTAKLDYLSELGVDALWLNPVTVSPMADHGYDVADPRDI
DPLFGGIDALDRLIAAAHDRGIRITMDLVPNHTSSAHPWFQAALAAGPGSAQRERYIFREGTGPDGLLPPNNWISVFGGP
AWTRIVEPDGQPGQWYLHLFDPEQPDLNWDNPEVFEDLEKTLRFWLDRGVDGFRIDVAHGMAKPPDLPDMEIAENRMLAE
TASDPRFDHQGVHDIHRNIRSVLDDYPGAVAVGEVWVYDNAAFAAYLRADELHLGFNFRLVRADFDADEIHDAIENSLAA
VALENATPTWTLSNHDVEREVTRYGGGALGLARARAMALVMLALPGVVFVYNGEELGLPNVDLPDEVLQDPVWERSDRTE
RGRDGCRVPMPWSGDAPPFGFSTTADTWLPMPAEWSSLTVERQLAEPDSMLHFFRRALRLRRDRCGVDGATLTQLSAEDG
VVTFRTDGGLTCVLNAGERPVDLPPGEVLLASAPLQAHSPSLRSPQDRRLPPDTAAWVV
>Mature_538_residues
GAMAHPPTADQPWWSRAVFYQVYPRSFHDSDGDGVGDLDGVTAKLDYLSELGVDALWLNPVTVSPMADHGYDVADPRDID
PLFGGIDALDRLIAAAHDRGIRITMDLVPNHTSSAHPWFQAALAAGPGSAQRERYIFREGTGPDGLLPPNNWISVFGGPA
WTRIVEPDGQPGQWYLHLFDPEQPDLNWDNPEVFEDLEKTLRFWLDRGVDGFRIDVAHGMAKPPDLPDMEIAENRMLAET
ASDPRFDHQGVHDIHRNIRSVLDDYPGAVAVGEVWVYDNAAFAAYLRADELHLGFNFRLVRADFDADEIHDAIENSLAAV
ALENATPTWTLSNHDVEREVTRYGGGALGLARARAMALVMLALPGVVFVYNGEELGLPNVDLPDEVLQDPVWERSDRTER
GRDGCRVPMPWSGDAPPFGFSTTADTWLPMPAEWSSLTVERQLAEPDSMLHFFRRALRLRRDRCGVDGATLTQLSAEDGV
VTFRTDGGLTCVLNAGERPVDLPPGEVLLASAPLQAHSPSLRSPQDRRLPPDTAAWVV

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=513, Percent_Identity=31.1890838206628, Blast_Score=252, Evalue=7e-67,
Organism=Escherichia coli, GI1790687, Length=492, Percent_Identity=36.9918699186992, Blast_Score=277, Evalue=1e-75,
Organism=Escherichia coli, GI1786604, Length=505, Percent_Identity=26.3366336633663, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1789995, Length=411, Percent_Identity=26.7639902676399, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI32565753, Length=512, Percent_Identity=24.609375, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI25147709, Length=533, Percent_Identity=25.703564727955, Blast_Score=115, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6322245, Length=495, Percent_Identity=32.3232323232323, Blast_Score=266, Evalue=9e-72,
Organism=Saccharomyces cerevisiae, GI6321726, Length=506, Percent_Identity=32.6086956521739, Blast_Score=251, Evalue=2e-67,
Organism=Saccharomyces cerevisiae, GI6319776, Length=507, Percent_Identity=32.1499013806706, Blast_Score=246, Evalue=6e-66,
Organism=Saccharomyces cerevisiae, GI6321731, Length=507, Percent_Identity=31.9526627218935, Blast_Score=245, Evalue=1e-65,
Organism=Saccharomyces cerevisiae, GI6324416, Length=507, Percent_Identity=32.5443786982249, Blast_Score=236, Evalue=6e-63,
Organism=Saccharomyces cerevisiae, GI6322241, Length=507, Percent_Identity=32.5443786982249, Blast_Score=236, Evalue=7e-63,
Organism=Saccharomyces cerevisiae, GI6322021, Length=507, Percent_Identity=32.5443786982249, Blast_Score=236, Evalue=7e-63,
Organism=Drosophila melanogaster, GI24586599, Length=528, Percent_Identity=34.280303030303, Blast_Score=278, Evalue=7e-75,
Organism=Drosophila melanogaster, GI24586597, Length=511, Percent_Identity=34.2465753424658, Blast_Score=278, Evalue=9e-75,
Organism=Drosophila melanogaster, GI221330053, Length=563, Percent_Identity=33.5701598579041, Blast_Score=271, Evalue=8e-73,
Organism=Drosophila melanogaster, GI24583747, Length=478, Percent_Identity=35.5648535564854, Blast_Score=268, Evalue=6e-72,
Organism=Drosophila melanogaster, GI24583749, Length=482, Percent_Identity=34.6473029045643, Blast_Score=268, Evalue=8e-72,
Organism=Drosophila melanogaster, GI24586587, Length=516, Percent_Identity=32.9457364341085, Blast_Score=264, Evalue=1e-70,
Organism=Drosophila melanogaster, GI24586591, Length=495, Percent_Identity=34.7474747474747, Blast_Score=262, Evalue=6e-70,
Organism=Drosophila melanogaster, GI24586589, Length=499, Percent_Identity=36.0721442885772, Blast_Score=261, Evalue=8e-70,
Organism=Drosophila melanogaster, GI24586593, Length=502, Percent_Identity=34.4621513944223, Blast_Score=254, Evalue=1e-67,
Organism=Drosophila melanogaster, GI24583745, Length=495, Percent_Identity=32.5252525252525, Blast_Score=253, Evalue=3e-67,
Organism=Drosophila melanogaster, GI45549022, Length=542, Percent_Identity=30.6273062730627, Blast_Score=250, Evalue=2e-66,
Organism=Drosophila melanogaster, GI281360393, Length=445, Percent_Identity=31.0112359550562, Blast_Score=176, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.10 [H]

Molecular weight: Translated: 59523; Mature: 59392

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAMAHPPTADQPWWSRAVFYQVYPRSFHDSDGDGVGDLDGVTAKLDYLSELGVDALWLN
CCCCCCCCCCCCCHHHHEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEC
PVTVSPMADHGYDVADPRDIDPLFGGIDALDRLIAAAHDRGIRITMDLVPNHTSSAHPWF
CEEECCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHH
QAALAAGPGSAQRERYIFREGTGPDGLLPPNNWISVFGGPAWTRIVEPDGQPGQWYLHLF
HHHHHCCCCCHHHCEEEEECCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCCEEEEEEE
DPEQPDLNWDNPEVFEDLEKTLRFWLDRGVDGFRIDVAHGMAKPPDLPDMEIAENRMLAE
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHCHHHHH
TASDPRFDHQGVHDIHRNIRSVLDDYPGAVAVGEVWVYDNAAFAAYLRADELHLGFNFRL
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEECCCEEEEEEEECEEEECCEEEE
VRADFDADEIHDAIENSLAAVALENATPTWTLSNHDVEREVTRYGGGALGLARARAMALV
EEECCCHHHHHHHHHCCEEEEEECCCCCEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHH
MLALPGVVFVYNGEELGLPNVDLPDEVLQDPVWERSDRTERGRDGCRVPMPWSGDAPPFG
HHHCCCEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
FSTTADTWLPMPAEWSSLTVERQLAEPDSMLHFFRRALRLRRDRCGVDGATLTQLSAEDG
CCCCCCCCCCCCCCCCCEEHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
VVTFRTDGGLTCVLNAGERPVDLPPGEVLLASAPLQAHSPSLRSPQDRRLPPDTAAWVV
EEEEEECCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GAMAHPPTADQPWWSRAVFYQVYPRSFHDSDGDGVGDLDGVTAKLDYLSELGVDALWLN
CCCCCCCCCCCCHHHHEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEC
PVTVSPMADHGYDVADPRDIDPLFGGIDALDRLIAAAHDRGIRITMDLVPNHTSSAHPWF
CEEECCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHH
QAALAAGPGSAQRERYIFREGTGPDGLLPPNNWISVFGGPAWTRIVEPDGQPGQWYLHLF
HHHHHCCCCCHHHCEEEEECCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCCEEEEEEE
DPEQPDLNWDNPEVFEDLEKTLRFWLDRGVDGFRIDVAHGMAKPPDLPDMEIAENRMLAE
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHCHHHHH
TASDPRFDHQGVHDIHRNIRSVLDDYPGAVAVGEVWVYDNAAFAAYLRADELHLGFNFRL
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEECCCEEEEEEEECEEEECCEEEE
VRADFDADEIHDAIENSLAAVALENATPTWTLSNHDVEREVTRYGGGALGLARARAMALV
EEECCCHHHHHHHHHCCEEEEEECCCCCEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHH
MLALPGVVFVYNGEELGLPNVDLPDEVLQDPVWERSDRTERGRDGCRVPMPWSGDAPPFG
HHHCCCEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
FSTTADTWLPMPAEWSSLTVERQLAEPDSMLHFFRRALRLRRDRCGVDGATLTQLSAEDG
CCCCCCCCCCCCCCCCCEEHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
VVTFRTDGGLTCVLNAGERPVDLPPGEVLLASAPLQAHSPSLRSPQDRRLPPDTAAWVV
EEEEEECCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8787404 [H]