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The map label for this gene is pepN [H]

Identifier: 119869710

GI number: 119869710

Start: 3878031

End: 3880634

Strand: Direct

Name: pepN [H]

Synonym: Mkms_3678

Alternate gene names: 119869710

Gene position: 3878031-3880634 (Clockwise)

Preceding gene: 119869709

Following gene: 119869711

Centisome position: 67.59

GC content: 68.66

Gene sequence:

>2604_bases
GTGGCACTTCCCAACCTGACCCGCGAGGCGGCCGTCGAACGCGCGGCCCTGATCACCGTCGACAACTACCGCATCGAACT
GGATCTCACCGACGGTGCCGGTGCCCCCGGTGAGAAGACCTTCCACTCGGTCACCACCGTCACGTTCGACGCGACGCCGG
GCGCCGACACCTACATCGACATCGCCGCGGACACCATCCGCGCGGCCACCCTCAACGGCCACGACGTCGACGTGTCGGGT
TACGACGAGTCGACCGGCATCCCGCTCGCGGGGTTGGCCGAGCACAACGTGCTCGTCGTCGACGCCGACTGCCGCTACTC
GAACACCGGCGAGGGACTGCACCGCTTCGTCGACCCGGTCGACGACGAGGTGTACCTGTACTCACAGTTCGAGACCGCCG
ACGCCAAGCGCATGTTCGCCTGCTTCGACCAGCCCGACCTCAAGGCGACGTTCGACGTCACGGTCACCGCGCCCGCGCAC
TGGGAGGTGGTGTCCAACGGCGCGCTGGAGGGCAGCCGTGACGACCGCGCCGCTCAAGCGAACGGCGGCACGAAGACCCA
CGTGTTCGTGCAGACGCCGCGGATGAGCACCTACCTCGTCGCCCTGATCGCCGGACCGTACGCCCGCTGGGACGATCTGT
ACCGCGACGAGCACGGTGAGATCCCGCTCGGGCTGTTCTGCCGCAAGTCGCTGGCCGAGTTCATGGACGCCGAGCGGCTG
TTCACCGAGACCAAGCAGGGATTCGGCTTCTACCACAACAACTTCGGGGTGCCCTACGCGTTCGGCAAGTACGACCAGCT
GTTCGTCCCGGAGTTCAACGCGGGCGCGATGGAGAACGCCGGAGCGGTGACGTTCCTGGAGGACTACGTCTTCCGCAGCA
AGGTCACCCGCGCCTCGTACGAGCGTCGCGCCGAGACCGTGCTCCACGAGATGGCGCACATGTGGTTCGGCGATCTGGTC
ACCATGACCTGGTGGGACGACCTGTGGCTCAACGAATCGTTCGCGACGTTCGCCTCGGTGCTGTGCCAGGCCGAGTCGAC
GGAGTACACCGAGGCGTGGACGACGTTCGCCAACGTGGAGAAGTCGTGGGCATACCGTCAGGACCAGTTGCCGTCGACGC
ATCCGGTTGCCGCCGACATCCCCGATCTGCACGCCGTCGAGGTGAACTTCGACGGGATCACCTACGCCAAGGGCGCCAGC
GTCCTCAAACAACTCGTCGCCTACGTCGGCCTGGAATCGTTCCTCGCCGGGCTGCGGGACTACTTCCGTGACCACGCCTT
CGGCAACGCGACGTTCGGCGATCTGCTCGGTGCGCTCGAGAAGGCTTCGGGCCGTGACCTTTCCGGGTGGGGCAGGCAGT
GGCTCAAGACCACCGGGCTCAACACGCTGCGCGCCGACTTCGACGTCGACGCCGACGGCCGGTTCACCCGCTTCGCCGTC
ACCCAGAGCGGTGCCGCACCGGGTGCCGGTGAGACACGCGTACACCGGCTGGCCATCGGCGTGTACGACGACGATCCGAC
CACCGGAAAGCTCGTGCGGGTGCACCGCGAGGAGCTCGACGTGGAAGGCGAGAGCACCGAAGTCCCCGCACTGCAAGGAG
TTCCGCGCGGAAAACTGGTGCTGGTCAACGACGACGACCTGACGTACTGCGCGTCGCGGCTGGATCCGGATTCGCTGCAG
ACGGTGCTCACCCGCATCGCCGACATCGCCGAACCGTTGCCGCGCACGCTGGCCTGGTCGGCGGCCTGGGAGATGACCCG
CGAGGCCGAACTGCGGGCCCGCGACTTCGTCGCGCTGGTGATGAGCGGTGTGCACGCCGAGACCGAGGTCGGCGTGGCGC
AGCGGCTGCTGCTGCAGGCGCAGACCGCGCTGAACTCCTACGCCGATCCGCAGTGGGCGCGTGAGACCGGCTGGCCGGCG
TTCGCCGACCGGCTGCTCGATCTGGCGCACGAATCGGCCCCGGGTTCGGACCACCAGTTGGCGTTCGTCAACGCGCTGTG
CGCGTCGGTGTTGTCGCGTAACCACGTCGCCGTGTTGGCGACCCTGCTCGACAACGAACCCGCCGCGGTGAACCTGACGG
GGCTGGTGCTCGACACCGACCTGCGGTGGCGCATCGTCACGGCGCTGGCCGCCAGCGGCGACATCGACGCCGACGGACCC
GAGACGCCGTTCATCGACGCCGAGGCGGAGCGCGATCCGACCGCGGCAGGCCGGCGCCACGCCGCGGCGGCGTCCGCGGC
GCGACCGCAGCCCGCGGTGAAAGAGGCTGCGTGGCAACAGGTCATCGAGGACGACACGCTGGCCAACATCACCACGCGCT
CGATCGTCGGCGGCATCGTGCAGCCGGGTCAGCAGGCGCTGCTGGCGCCGTACACGGAGAAGTACTTCGCCGCCATTGCG
GGGGTGTGGGAGCGCCGGTCCAGTGAGGTCGCCCAGACGGTGGTGATCGGCCTGTACCCGTCGTGGGACATCAGCGACGA
GGGTCTGGCGGCCGCGGACCGCTTCCTCTCCGGTGACGTGCCGCCGGCGCTGCGCCGACTGGTGCTCGAAGGCCGCGCGG
GGGTGGAACGCGCACTGCGGGCGCGCAAGCACGACGTGAGCTGA

Upstream 100 bases:

>100_bases
CAGATGTACTGCCCGCAGATGGTGTCGTCGGTGGGCAACGGCACGTTCCTGAACTGGCTGCAGACGACGAGGTTCCCTCG
CGCCCGATAGGTTGGTGGGC

Downstream 100 bases:

>100_bases
CCGCACCTCTCCTCGCTCGAGCGTGCGGGTCGGCACACGACACGCCGCGGTGGTTTCCGCGGTTGCGCACGCTCGCGCGG
CATCCTCGGGCGGTGGCGGT

Product: aminopeptidase N

Products: NA

Alternate protein names: Alanine aminopeptidase; Lysyl aminopeptidase; Lys-AP [H]

Number of amino acids: Translated: 867; Mature: 866

Protein sequence:

>867_residues
MALPNLTREAAVERAALITVDNYRIELDLTDGAGAPGEKTFHSVTTVTFDATPGADTYIDIAADTIRAATLNGHDVDVSG
YDESTGIPLAGLAEHNVLVVDADCRYSNTGEGLHRFVDPVDDEVYLYSQFETADAKRMFACFDQPDLKATFDVTVTAPAH
WEVVSNGALEGSRDDRAAQANGGTKTHVFVQTPRMSTYLVALIAGPYARWDDLYRDEHGEIPLGLFCRKSLAEFMDAERL
FTETKQGFGFYHNNFGVPYAFGKYDQLFVPEFNAGAMENAGAVTFLEDYVFRSKVTRASYERRAETVLHEMAHMWFGDLV
TMTWWDDLWLNESFATFASVLCQAESTEYTEAWTTFANVEKSWAYRQDQLPSTHPVAADIPDLHAVEVNFDGITYAKGAS
VLKQLVAYVGLESFLAGLRDYFRDHAFGNATFGDLLGALEKASGRDLSGWGRQWLKTTGLNTLRADFDVDADGRFTRFAV
TQSGAAPGAGETRVHRLAIGVYDDDPTTGKLVRVHREELDVEGESTEVPALQGVPRGKLVLVNDDDLTYCASRLDPDSLQ
TVLTRIADIAEPLPRTLAWSAAWEMTREAELRARDFVALVMSGVHAETEVGVAQRLLLQAQTALNSYADPQWARETGWPA
FADRLLDLAHESAPGSDHQLAFVNALCASVLSRNHVAVLATLLDNEPAAVNLTGLVLDTDLRWRIVTALAASGDIDADGP
ETPFIDAEAERDPTAAGRRHAAAASAARPQPAVKEAAWQQVIEDDTLANITTRSIVGGIVQPGQQALLAPYTEKYFAAIA
GVWERRSSEVAQTVVIGLYPSWDISDEGLAAADRFLSGDVPPALRRLVLEGRAGVERALRARKHDVS

Sequences:

>Translated_867_residues
MALPNLTREAAVERAALITVDNYRIELDLTDGAGAPGEKTFHSVTTVTFDATPGADTYIDIAADTIRAATLNGHDVDVSG
YDESTGIPLAGLAEHNVLVVDADCRYSNTGEGLHRFVDPVDDEVYLYSQFETADAKRMFACFDQPDLKATFDVTVTAPAH
WEVVSNGALEGSRDDRAAQANGGTKTHVFVQTPRMSTYLVALIAGPYARWDDLYRDEHGEIPLGLFCRKSLAEFMDAERL
FTETKQGFGFYHNNFGVPYAFGKYDQLFVPEFNAGAMENAGAVTFLEDYVFRSKVTRASYERRAETVLHEMAHMWFGDLV
TMTWWDDLWLNESFATFASVLCQAESTEYTEAWTTFANVEKSWAYRQDQLPSTHPVAADIPDLHAVEVNFDGITYAKGAS
VLKQLVAYVGLESFLAGLRDYFRDHAFGNATFGDLLGALEKASGRDLSGWGRQWLKTTGLNTLRADFDVDADGRFTRFAV
TQSGAAPGAGETRVHRLAIGVYDDDPTTGKLVRVHREELDVEGESTEVPALQGVPRGKLVLVNDDDLTYCASRLDPDSLQ
TVLTRIADIAEPLPRTLAWSAAWEMTREAELRARDFVALVMSGVHAETEVGVAQRLLLQAQTALNSYADPQWARETGWPA
FADRLLDLAHESAPGSDHQLAFVNALCASVLSRNHVAVLATLLDNEPAAVNLTGLVLDTDLRWRIVTALAASGDIDADGP
ETPFIDAEAERDPTAAGRRHAAAASAARPQPAVKEAAWQQVIEDDTLANITTRSIVGGIVQPGQQALLAPYTEKYFAAIA
GVWERRSSEVAQTVVIGLYPSWDISDEGLAAADRFLSGDVPPALRRLVLEGRAGVERALRARKHDVS
>Mature_866_residues
ALPNLTREAAVERAALITVDNYRIELDLTDGAGAPGEKTFHSVTTVTFDATPGADTYIDIAADTIRAATLNGHDVDVSGY
DESTGIPLAGLAEHNVLVVDADCRYSNTGEGLHRFVDPVDDEVYLYSQFETADAKRMFACFDQPDLKATFDVTVTAPAHW
EVVSNGALEGSRDDRAAQANGGTKTHVFVQTPRMSTYLVALIAGPYARWDDLYRDEHGEIPLGLFCRKSLAEFMDAERLF
TETKQGFGFYHNNFGVPYAFGKYDQLFVPEFNAGAMENAGAVTFLEDYVFRSKVTRASYERRAETVLHEMAHMWFGDLVT
MTWWDDLWLNESFATFASVLCQAESTEYTEAWTTFANVEKSWAYRQDQLPSTHPVAADIPDLHAVEVNFDGITYAKGASV
LKQLVAYVGLESFLAGLRDYFRDHAFGNATFGDLLGALEKASGRDLSGWGRQWLKTTGLNTLRADFDVDADGRFTRFAVT
QSGAAPGAGETRVHRLAIGVYDDDPTTGKLVRVHREELDVEGESTEVPALQGVPRGKLVLVNDDDLTYCASRLDPDSLQT
VLTRIADIAEPLPRTLAWSAAWEMTREAELRARDFVALVMSGVHAETEVGVAQRLLLQAQTALNSYADPQWARETGWPAF
ADRLLDLAHESAPGSDHQLAFVNALCASVLSRNHVAVLATLLDNEPAAVNLTGLVLDTDLRWRIVTALAASGDIDADGPE
TPFIDAEAERDPTAAGRRHAAAASAARPQPAVKEAAWQQVIEDDTLANITTRSIVGGIVQPGQQALLAPYTEKYFAAIAG
VWERRSSEVAQTVVIGLYPSWDISDEGLAAADRFLSGDVPPALRRLVLEGRAGVERALRARKHDVS

Specific function: Aminopeptidase with broad substrate specificity to several peptides. Shows strong preference for leucine but cleaves also next to Arg and lysine in peptide-bond-containing substrates [H]

COG id: COG0308

COG function: function code E; Aminopeptidase N

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M1 family [H]

Homologues:

Organism=Homo sapiens, GI158937236, Length=455, Percent_Identity=30.3296703296703, Blast_Score=199, Evalue=1e-50,
Organism=Homo sapiens, GI157266300, Length=450, Percent_Identity=29.5555555555556, Blast_Score=177, Evalue=5e-44,
Organism=Homo sapiens, GI132814467, Length=342, Percent_Identity=32.1637426900585, Blast_Score=176, Evalue=6e-44,
Organism=Homo sapiens, GI310123622, Length=311, Percent_Identity=34.4051446945338, Blast_Score=172, Evalue=1e-42,
Organism=Homo sapiens, GI61742777, Length=368, Percent_Identity=30.4347826086957, Blast_Score=171, Evalue=3e-42,
Organism=Homo sapiens, GI61742775, Length=368, Percent_Identity=30.4347826086957, Blast_Score=171, Evalue=3e-42,
Organism=Homo sapiens, GI310133497, Length=311, Percent_Identity=33.7620578778135, Blast_Score=163, Evalue=6e-40,
Organism=Homo sapiens, GI7019561, Length=332, Percent_Identity=33.1325301204819, Blast_Score=158, Evalue=3e-38,
Organism=Homo sapiens, GI194239713, Length=349, Percent_Identity=30.0859598853868, Blast_Score=152, Evalue=2e-36,
Organism=Homo sapiens, GI94818901, Length=319, Percent_Identity=31.974921630094, Blast_Score=150, Evalue=4e-36,
Organism=Homo sapiens, GI94818891, Length=319, Percent_Identity=31.974921630094, Blast_Score=150, Evalue=4e-36,
Organism=Homo sapiens, GI194306629, Length=315, Percent_Identity=29.2063492063492, Blast_Score=137, Evalue=7e-32,
Organism=Homo sapiens, GI11641261, Length=315, Percent_Identity=29.2063492063492, Blast_Score=137, Evalue=7e-32,
Organism=Homo sapiens, GI4505029, Length=442, Percent_Identity=23.9819004524887, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI40316915, Length=230, Percent_Identity=26.5217391304348, Blast_Score=77, Evalue=9e-14,
Organism=Escherichia coli, GI1787163, Length=515, Percent_Identity=27.378640776699, Blast_Score=107, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI71989076, Length=422, Percent_Identity=30.0947867298578, Blast_Score=185, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI71989071, Length=422, Percent_Identity=30.0947867298578, Blast_Score=185, Evalue=9e-47,
Organism=Caenorhabditis elegans, GI115533278, Length=319, Percent_Identity=34.1692789968652, Blast_Score=170, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI115533276, Length=355, Percent_Identity=32.6760563380282, Blast_Score=170, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI71990873, Length=351, Percent_Identity=31.6239316239316, Blast_Score=149, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI133903840, Length=317, Percent_Identity=30.2839116719243, Blast_Score=143, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI17569221, Length=380, Percent_Identity=30.2631578947368, Blast_Score=142, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI17565628, Length=462, Percent_Identity=26.1904761904762, Blast_Score=142, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI193206928, Length=329, Percent_Identity=30.0911854103343, Blast_Score=117, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI193206926, Length=329, Percent_Identity=30.0911854103343, Blast_Score=116, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17569225, Length=364, Percent_Identity=27.4725274725275, Blast_Score=107, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17544504, Length=310, Percent_Identity=28.0645161290323, Blast_Score=95, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71984339, Length=322, Percent_Identity=26.3975155279503, Blast_Score=85, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71984353, Length=322, Percent_Identity=26.3975155279503, Blast_Score=85, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI9755335, Length=356, Percent_Identity=35.1123595505618, Blast_Score=199, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6321837, Length=361, Percent_Identity=37.1191135734072, Blast_Score=197, Evalue=6e-51,
Organism=Saccharomyces cerevisiae, GI6322054, Length=374, Percent_Identity=22.9946524064171, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24655252, Length=345, Percent_Identity=36.231884057971, Blast_Score=194, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24655257, Length=345, Percent_Identity=36.231884057971, Blast_Score=194, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24655274, Length=344, Percent_Identity=35.4651162790698, Blast_Score=193, Evalue=4e-49,
Organism=Drosophila melanogaster, GI24655260, Length=344, Percent_Identity=35.4651162790698, Blast_Score=193, Evalue=4e-49,
Organism=Drosophila melanogaster, GI24655265, Length=344, Percent_Identity=35.4651162790698, Blast_Score=193, Evalue=4e-49,
Organism=Drosophila melanogaster, GI24655268, Length=344, Percent_Identity=35.4651162790698, Blast_Score=193, Evalue=4e-49,
Organism=Drosophila melanogaster, GI21358341, Length=364, Percent_Identity=32.6923076923077, Blast_Score=172, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24651025, Length=350, Percent_Identity=32.5714285714286, Blast_Score=166, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24651023, Length=350, Percent_Identity=32.5714285714286, Blast_Score=166, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24651021, Length=350, Percent_Identity=32.5714285714286, Blast_Score=166, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24646514, Length=404, Percent_Identity=31.9306930693069, Blast_Score=164, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24646516, Length=343, Percent_Identity=33.2361516034985, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24646518, Length=343, Percent_Identity=33.2361516034985, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI161078673, Length=356, Percent_Identity=29.7752808988764, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI28571901, Length=356, Percent_Identity=29.7752808988764, Blast_Score=157, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24651016, Length=302, Percent_Identity=34.4370860927152, Blast_Score=157, Evalue=4e-38,
Organism=Drosophila melanogaster, GI45550850, Length=323, Percent_Identity=31.5789473684211, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24650973, Length=323, Percent_Identity=31.5789473684211, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI221379089, Length=356, Percent_Identity=28.0898876404494, Blast_Score=149, Evalue=8e-36,
Organism=Drosophila melanogaster, GI24646512, Length=359, Percent_Identity=30.3621169916435, Blast_Score=146, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24646510, Length=359, Percent_Identity=30.3621169916435, Blast_Score=146, Evalue=5e-35,
Organism=Drosophila melanogaster, GI28571792, Length=345, Percent_Identity=30.7246376811594, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24648786, Length=321, Percent_Identity=30.5295950155763, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24648790, Length=326, Percent_Identity=30.9815950920245, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI221330574, Length=345, Percent_Identity=27.536231884058, Blast_Score=123, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24648784, Length=315, Percent_Identity=25.3968253968254, Blast_Score=115, Evalue=1e-25,
Organism=Drosophila melanogaster, GI281362224, Length=332, Percent_Identity=28.0120481927711, Blast_Score=112, Evalue=1e-24,
Organism=Drosophila melanogaster, GI281362221, Length=297, Percent_Identity=25.5892255892256, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI221458256, Length=332, Percent_Identity=28.0120481927711, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24641062, Length=445, Percent_Identity=26.0674157303371, Blast_Score=96, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24585062, Length=392, Percent_Identity=24.4897959183673, Blast_Score=86, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24585064, Length=392, Percent_Identity=24.4897959183673, Blast_Score=86, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24585066, Length=392, Percent_Identity=24.4897959183673, Blast_Score=86, Evalue=9e-17,
Organism=Drosophila melanogaster, GI45550350, Length=392, Percent_Identity=24.4897959183673, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24584504, Length=340, Percent_Identity=25.2941176470588, Blast_Score=83, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012778
- InterPro:   IPR001930
- InterPro:   IPR014782 [H]

Pfam domain/function: PF01433 Peptidase_M1 [H]

EC number: =3.4.11.2 [H]

Molecular weight: Translated: 94853; Mature: 94722

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALPNLTREAAVERAALITVDNYRIELDLTDGAGAPGEKTFHSVTTVTFDATPGADTYID
CCCCCCHHHHHHHHEEEEEEECEEEEEEECCCCCCCCCCCEEEEEEEEEECCCCCCCEEE
IAADTIRAATLNGHDVDVSGYDESTGIPLAGLAEHNVLVVDADCRYSNTGEGLHRFVDPV
EEHHHEEEEECCCCEEEECCCCCCCCCCEEEECCCCEEEEECCCCCCCCCHHHHHHCCCC
DDEVYLYSQFETADAKRMFACFDQPDLKATFDVTVTAPAHWEVVSNGALEGSRDDRAAQA
CCCEEEEEECCCCCHHHHHHHCCCCCCCEEEEEEEECCCCEEEECCCCCCCCCCCCCHHC
NGGTKTHVFVQTPRMSTYLVALIAGPYARWDDLYRDEHGEIPLGLFCRKSLAEFMDAERL
CCCCEEEEEEECCCCHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
FTETKQGFGFYHNNFGVPYAFGKYDQLFVPEFNAGAMENAGAVTFLEDYVFRSKVTRASY
HHHHHHCCCEEECCCCCCEECCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ERRAETVLHEMAHMWFGDLVTMTWWDDLWLNESFATFASVLCQAESTEYTEAWTTFANVE
HHHHHHHHHHHHHHHHHHHEEEEEHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
KSWAYRQDQLPSTHPVAADIPDLHAVEVNFDGITYAKGASVLKQLVAYVGLESFLAGLRD
HHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCEEEHHHHHHHHHHHHHHCHHHHHHHHHH
YFRDHAFGNATFGDLLGALEKASGRDLSGWGRQWLKTTGLNTLRADFDVDADGRFTRFAV
HHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEECCCCCCCCCCEEEEEE
TQSGAAPGAGETRVHRLAIGVYDDDPTTGKLVRVHREELDVEGESTEVPALQGVPRGKLV
EECCCCCCCCCCEEEEEEEEEECCCCCCCCEEEEEHHHCCCCCCCCCCCHHCCCCCCCEE
LVNDDDLTYCASRLDPDSLQTVLTRIADIAEPLPRTLAWSAAWEMTREAELRARDFVALV
EECCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MSGVHAETEVGVAQRLLLQAQTALNSYADPQWARETGWPAFADRLLDLAHESAPGSDHQL
HHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCHH
AFVNALCASVLSRNHVAVLATLLDNEPAAVNLTGLVLDTDLRWRIVTALAASGDIDADGP
HHHHHHHHHHHCCCCCEEEEEHHCCCCCEEEEEEEEEECCCCEEEEEHHHCCCCCCCCCC
ETPFIDAEAERDPTAAGRRHAAAASAARPQPAVKEAAWQQVIEDDTLANITTRSIVGGIV
CCCEECCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
QPGQQALLAPYTEKYFAAIAGVWERRSSEVAQTVVIGLYPSWDISDEGLAAADRFLSGDV
CCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCHHHHHHHHCCCC
PPALRRLVLEGRAGVERALRARKHDVS
CHHHHHHHHCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
ALPNLTREAAVERAALITVDNYRIELDLTDGAGAPGEKTFHSVTTVTFDATPGADTYID
CCCCCHHHHHHHHEEEEEEECEEEEEEECCCCCCCCCCCEEEEEEEEEECCCCCCCEEE
IAADTIRAATLNGHDVDVSGYDESTGIPLAGLAEHNVLVVDADCRYSNTGEGLHRFVDPV
EEHHHEEEEECCCCEEEECCCCCCCCCCEEEECCCCEEEEECCCCCCCCCHHHHHHCCCC
DDEVYLYSQFETADAKRMFACFDQPDLKATFDVTVTAPAHWEVVSNGALEGSRDDRAAQA
CCCEEEEEECCCCCHHHHHHHCCCCCCCEEEEEEEECCCCEEEECCCCCCCCCCCCCHHC
NGGTKTHVFVQTPRMSTYLVALIAGPYARWDDLYRDEHGEIPLGLFCRKSLAEFMDAERL
CCCCEEEEEEECCCCHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
FTETKQGFGFYHNNFGVPYAFGKYDQLFVPEFNAGAMENAGAVTFLEDYVFRSKVTRASY
HHHHHHCCCEEECCCCCCEECCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ERRAETVLHEMAHMWFGDLVTMTWWDDLWLNESFATFASVLCQAESTEYTEAWTTFANVE
HHHHHHHHHHHHHHHHHHHEEEEEHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
KSWAYRQDQLPSTHPVAADIPDLHAVEVNFDGITYAKGASVLKQLVAYVGLESFLAGLRD
HHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCEEEHHHHHHHHHHHHHHCHHHHHHHHHH
YFRDHAFGNATFGDLLGALEKASGRDLSGWGRQWLKTTGLNTLRADFDVDADGRFTRFAV
HHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEECCCCCCCCCCEEEEEE
TQSGAAPGAGETRVHRLAIGVYDDDPTTGKLVRVHREELDVEGESTEVPALQGVPRGKLV
EECCCCCCCCCCEEEEEEEEEECCCCCCCCEEEEEHHHCCCCCCCCCCCHHCCCCCCCEE
LVNDDDLTYCASRLDPDSLQTVLTRIADIAEPLPRTLAWSAAWEMTREAELRARDFVALV
EECCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MSGVHAETEVGVAQRLLLQAQTALNSYADPQWARETGWPAFADRLLDLAHESAPGSDHQL
HHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCHH
AFVNALCASVLSRNHVAVLATLLDNEPAAVNLTGLVLDTDLRWRIVTALAASGDIDADGP
HHHHHHHHHHHCCCCCEEEEEHHCCCCCEEEEEEEEEECCCCEEEEEHHHCCCCCCCCCC
ETPFIDAEAERDPTAAGRRHAAAASAARPQPAVKEAAWQQVIEDDTLANITTRSIVGGIV
CCCEECCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
QPGQQALLAPYTEKYFAAIAGVWERRSSEVAQTVVIGLYPSWDISDEGLAAADRFLSGDV
CCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCHHHHHHHHCCCC
PPALRRLVLEGRAGVERALRARKHDVS
CHHHHHHHHCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7909302; 7765336 [H]