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The map label for this gene is fdhD [H]

Identifier: 119869677

GI number: 119869677

Start: 3838456

End: 3839280

Strand: Direct

Name: fdhD [H]

Synonym: Mkms_3645

Alternate gene names: 119869677

Gene position: 3838456-3839280 (Clockwise)

Preceding gene: 119869676

Following gene: 119869678

Centisome position: 66.9

GC content: 69.33

Gene sequence:

>825_bases
ATGGGTCGTGTCACCGCGCGGCGGCGCATACACCACATCACCGCCGAAACCAGCGTCGCGCGGCCCGAGACGCTGGCGGT
CGAAGAGCCACTCGAGATCCGCGTCGGGGGCGAACCACTCACCGTCACGATGCGTACACCCGGGTCGGATGTCGAACTGG
CACAAGGCTTTCTGCTCACCGAAGGAATCATCGGGCACCGCGACGACGTGCTGACGGTGCGGTACTGCCGCGGCGCGGGC
GATGACGGCGTCAACACCTACAACGTGCTCGACGTGGCGTTGGCGCCGCACGTGTCCGCACCCAGTCCGGATCTGCGGCG
CAACTTCTATTCCACCTCGTCGTGCGGGGTGTGCGGCAAGGCCTCCCTGGAGGCCGTGCAACTCATCAGCCGACACGGAC
CCGGAGACGACCCCACCCGGGTGGGCGCCGACACGTTGTCCGCACTGCCGGATCGGCTACGGGCGGCGCAGAAGGTGTTC
GCCACCACCGGCGGGCTGCACGGCGCCGCGCTGTTCACCGCCGACGGCGGGATGCTCGTCGTGCGCGAGGATGTCGGTAG
GCACAACGCCGTCGACAAGGTGATCGGCTGGGCACTCGAGGCCGACCGCATCCCCCTGACCGGGACGGTGCTTCTGGTCA
GCGGCCGGGCATCCTTCGAACTGACGCAGAAGGCCGTCATGGCGGGTATCCCGGTGCTCGCCGCGGTATCGGCGCCGTCG
TCGCTGGCGGTCGACCTGGCCGGCCAGTCCGGCCTCACGCTGGTGGCCTTCCTGCGCGGCCAGTCGATGAACGTCTACAC
CCGGCCGGACCGCATCACCCGCTGA

Upstream 100 bases:

>100_bases
CTACACCGTCGCCGTCGACCCCACGACCGGCAGGCTGTTCGTCGCCGGTCTGACCGGAGGCGTGGTCCAGATCATCGACG
TCACCTCCTAGGCTGGAGGC

Downstream 100 bases:

>100_bases
TCTCCACGCGATCTCCACGAAACCTCCAAGTCCGCACGCCGTCACCTGGCTGACCATCGAAGTCCGATGGACACCGCCAA
GCCAGGAGTTCGAGATGCCG

Product: formate dehydrogenase accessory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MGRVTARRRIHHITAETSVARPETLAVEEPLEIRVGGEPLTVTMRTPGSDVELAQGFLLTEGIIGHRDDVLTVRYCRGAG
DDGVNTYNVLDVALAPHVSAPSPDLRRNFYSTSSCGVCGKASLEAVQLISRHGPGDDPTRVGADTLSALPDRLRAAQKVF
ATTGGLHGAALFTADGGMLVVREDVGRHNAVDKVIGWALEADRIPLTGTVLLVSGRASFELTQKAVMAGIPVLAAVSAPS
SLAVDLAGQSGLTLVAFLRGQSMNVYTRPDRITR

Sequences:

>Translated_274_residues
MGRVTARRRIHHITAETSVARPETLAVEEPLEIRVGGEPLTVTMRTPGSDVELAQGFLLTEGIIGHRDDVLTVRYCRGAG
DDGVNTYNVLDVALAPHVSAPSPDLRRNFYSTSSCGVCGKASLEAVQLISRHGPGDDPTRVGADTLSALPDRLRAAQKVF
ATTGGLHGAALFTADGGMLVVREDVGRHNAVDKVIGWALEADRIPLTGTVLLVSGRASFELTQKAVMAGIPVLAAVSAPS
SLAVDLAGQSGLTLVAFLRGQSMNVYTRPDRITR
>Mature_273_residues
GRVTARRRIHHITAETSVARPETLAVEEPLEIRVGGEPLTVTMRTPGSDVELAQGFLLTEGIIGHRDDVLTVRYCRGAGD
DGVNTYNVLDVALAPHVSAPSPDLRRNFYSTSSCGVCGKASLEAVQLISRHGPGDDPTRVGADTLSALPDRLRAAQKVFA
TTGGLHGAALFTADGGMLVVREDVGRHNAVDKVIGWALEADRIPLTGTVLLVSGRASFELTQKAVMAGIPVLAAVSAPSS
LAVDLAGQSGLTLVAFLRGQSMNVYTRPDRITR

Specific function: Necessary for formate dehydrogenase activity [H]

COG id: COG1526

COG function: function code C; Uncharacterized protein required for formate dehydrogenase activity

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fdhD family [H]

Homologues:

Organism=Escherichia coli, GI1790329, Length=289, Percent_Identity=32.5259515570934, Blast_Score=105, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003786 [H]

Pfam domain/function: PF02634 FdhD-NarQ [H]

EC number: NA

Molecular weight: Translated: 28925; Mature: 28794

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS00626 RCC1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRVTARRRIHHITAETSVARPETLAVEEPLEIRVGGEPLTVTMRTPGSDVELAQGFLLT
CCCCCHHHHHEEEECCCCCCCCCEEEECCCEEEEECCCEEEEEEECCCCCHHHHCCEEEE
EGIIGHRDDVLTVRYCRGAGDDGVNTYNVLDVALAPHVSAPSPDLRRNFYSTSSCGVCGK
CCCCCCCCCEEEEEEECCCCCCCCCEEEEEEEEECCCCCCCCCHHHHHCCCCCCCCCCCC
ASLEAVQLISRHGPGDDPTRVGADTLSALPDRLRAAQKVFATTGGLHGAALFTADGGMLV
CHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEE
VREDVGRHNAVDKVIGWALEADRIPLTGTVLLVSGRASFELTQKAVMAGIPVLAAVSAPS
EECCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCCEEEECCCC
SLAVDLAGQSGLTLVAFLRGQSMNVYTRPDRITR
CEEEEECCCCCCEEEEEECCCCCEEEECCHHCCC
>Mature Secondary Structure 
GRVTARRRIHHITAETSVARPETLAVEEPLEIRVGGEPLTVTMRTPGSDVELAQGFLLT
CCCCHHHHHEEEECCCCCCCCCEEEECCCEEEEECCCEEEEEEECCCCCHHHHCCEEEE
EGIIGHRDDVLTVRYCRGAGDDGVNTYNVLDVALAPHVSAPSPDLRRNFYSTSSCGVCGK
CCCCCCCCCEEEEEEECCCCCCCCCEEEEEEEEECCCCCCCCCHHHHHCCCCCCCCCCCC
ASLEAVQLISRHGPGDDPTRVGADTLSALPDRLRAAQKVFATTGGLHGAALFTADGGMLV
CHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEE
VREDVGRHNAVDKVIGWALEADRIPLTGTVLLVSGRASFELTQKAVMAGIPVLAAVSAPS
EECCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCCEEEECCCC
SLAVDLAGQSGLTLVAFLRGQSMNVYTRPDRITR
CEEEEECCCCCCEEEEEECCCCCEEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]