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The map label for this gene is ctaD [H]

Identifier: 119869533

GI number: 119869533

Start: 3677166

End: 3678914

Strand: Direct

Name: ctaD [H]

Synonym: Mkms_3501

Alternate gene names: 119869533

Gene position: 3677166-3678914 (Clockwise)

Preceding gene: 119869532

Following gene: 119869535

Centisome position: 64.09

GC content: 64.78

Gene sequence:

>1749_bases
GTGACAACCGAATCCGTTGTGCAGCCGACGTTGACGGCCAGGCGTCCGTTTCCCGAACGGCTGGGCCCCAAGGGCAACCT
GATCTACAAGGTCATCACGACCACCGATCACAAGCTGATCGGGATCATGTACTGCGTCGCCTGCTTCGCATTCTTCCTGG
TCGGCGGGTTGATGGCGCTGTTCATGCGCACCGAACTCGCGGTCCCCGGGCTGCAGTTCCTGTCGAACGAGCAGTACAAC
CAGCTGTTCACCATGCACGGCACCGCGATGCTGCTGTTCTACGCGACGCCCATCGTGTTCGGGTTCGCGAACCTGGTGCT
GCCGCTGCAGATCGGCGCCCCGGACGTGGCGTTCCCGCGCCTCAACGCGCTGTCGTTCTGGCTGTTCGTCTTCGGTGCGC
TGATCGCGCTGGCCGGGTTCATCACCCCCAGTGGTGCCGCGGACTTCGGCTGGACCGCCTATACGCCGCTGTCCGATGCG
GTGCACTCACCCGGGCCGGGTGGTGACCTGTGGATCTTCGGCTTGGGTGTGGGCGGTCTTGGCACCATCCTCGGCGGCGT
CAACATGATCACCACCGTGGTGTGCATGCGCGCCCCCGGCATGACGATGTTCCGGATGCCGATCTTCACCTGGAACATCC
TGGTGACCTCGATCCTGGTGCTGCTGATCTTCCCGCTGCTGACCGCGGCGCTGTTCGCCCTCGCCGCAGACCGCCACCTC
GGTGCGCACATCTACGACCCGGCCAACGGCGGTGTGCTGCTGTGGCAGCACCTGTTCTGGTTCTTCGGCCACCCCGAGGT
GTATGTCATCGCGCTGCCGTTCTTCGGCATCGTCAGTGAGATCTTCCCGGTGTTCTCCCGCAAGCCGATCTTCGGCTACA
CCACCCTGATCTACGCCACCATCGCGATCGCCGCGCTGTCGGTGGCGGTGTGGGCGCACCACATGTTCGCGACCGGAGCC
GTTCTCCTGCCGTTCTTCTCGTTCATGACGTTCCTCATCGCGGTGCCGACGGGGATCAAGTTCTTCAACTGGATCGGCAC
GATGTGGCGGGGTCAACTCACCTTCCAGACACCGATGCTGTTCTCGGTGGGCTTCCTGTTGACGTTCCTGCTCGGTGGTC
TGTCGGGGGTGCTGCTGGCCAGCCCGCCGCTGGACTTCCACGTCACCGACAGCTACTTCGTCATCGCGCACTTCCACTAC
GTGCTGTTCGGCACCATCGTGTTCGCCACCTATGCCGGGATCTACTTCTGGTTCCCGAAGATGACCGGCCGACTGCTCGA
CGAGAAGCTGGGCAAGCTGCACTTCTGGTTGACCTTCATCGGCTTCCACACCACGTTCCTGGTGCAGCACTGGGTCGGTG
ACGAGGGTATGCCGCGCCGCTACGCCGACTACCTGCCGTCGGACGGGTTCACCACGCTCAACATCGTCTCGACCATCGGG
GCGTTCATCCTGGGCATCTCCACGCTGCCGTTCCTGTGGAACATCTTCCGCAGCTGGCGCTACGGCGAGCCCGTCGTGGT
CGACGACCCGTGGGGGCACGGCAACTCACTGGAGTGGGCCACCAGCTGCCCGCCGCCGCGGCACAACTTCACCGAACTGC
CCCGCATCCGGTCCGAGCGCCCCGCGTTCGAGCTGCACTACCCGCACATGGTCGAGCGGATGCGCGCCGAGGCGCACATC
GGCCGCCACGCGACCGCCGGAGAGATCCAGGAGGGCTACGGGCCACGAACGGAGCCCGACCGCAGCTGA

Upstream 100 bases:

>100_bases
CATATTCGTGATCCGACCGGTCCTCGGTTTCGGGTCACCGCGGCCCCGATCGGTCTAGCATCGGAACGACGATCGATTTC
TCGACGTTCCGGGGGTGTCC

Downstream 100 bases:

>100_bases
GCTGACTTGGCTCTCCCGGCTCAGGATTTCTCGGAGTCGGATTTCTCGGATTTCTCGGAGTCGTCGCTGTCGTCCGACTC
GTCGTCATCGGAAGACTTCT

Product: cytochrome-c oxidase

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 582; Mature: 581

Protein sequence:

>582_residues
MTTESVVQPTLTARRPFPERLGPKGNLIYKVITTTDHKLIGIMYCVACFAFFLVGGLMALFMRTELAVPGLQFLSNEQYN
QLFTMHGTAMLLFYATPIVFGFANLVLPLQIGAPDVAFPRLNALSFWLFVFGALIALAGFITPSGAADFGWTAYTPLSDA
VHSPGPGGDLWIFGLGVGGLGTILGGVNMITTVVCMRAPGMTMFRMPIFTWNILVTSILVLLIFPLLTAALFALAADRHL
GAHIYDPANGGVLLWQHLFWFFGHPEVYVIALPFFGIVSEIFPVFSRKPIFGYTTLIYATIAIAALSVAVWAHHMFATGA
VLLPFFSFMTFLIAVPTGIKFFNWIGTMWRGQLTFQTPMLFSVGFLLTFLLGGLSGVLLASPPLDFHVTDSYFVIAHFHY
VLFGTIVFATYAGIYFWFPKMTGRLLDEKLGKLHFWLTFIGFHTTFLVQHWVGDEGMPRRYADYLPSDGFTTLNIVSTIG
AFILGISTLPFLWNIFRSWRYGEPVVVDDPWGHGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHMVERMRAEAHI
GRHATAGEIQEGYGPRTEPDRS

Sequences:

>Translated_582_residues
MTTESVVQPTLTARRPFPERLGPKGNLIYKVITTTDHKLIGIMYCVACFAFFLVGGLMALFMRTELAVPGLQFLSNEQYN
QLFTMHGTAMLLFYATPIVFGFANLVLPLQIGAPDVAFPRLNALSFWLFVFGALIALAGFITPSGAADFGWTAYTPLSDA
VHSPGPGGDLWIFGLGVGGLGTILGGVNMITTVVCMRAPGMTMFRMPIFTWNILVTSILVLLIFPLLTAALFALAADRHL
GAHIYDPANGGVLLWQHLFWFFGHPEVYVIALPFFGIVSEIFPVFSRKPIFGYTTLIYATIAIAALSVAVWAHHMFATGA
VLLPFFSFMTFLIAVPTGIKFFNWIGTMWRGQLTFQTPMLFSVGFLLTFLLGGLSGVLLASPPLDFHVTDSYFVIAHFHY
VLFGTIVFATYAGIYFWFPKMTGRLLDEKLGKLHFWLTFIGFHTTFLVQHWVGDEGMPRRYADYLPSDGFTTLNIVSTIG
AFILGISTLPFLWNIFRSWRYGEPVVVDDPWGHGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHMVERMRAEAHI
GRHATAGEIQEGYGPRTEPDRS
>Mature_581_residues
TTESVVQPTLTARRPFPERLGPKGNLIYKVITTTDHKLIGIMYCVACFAFFLVGGLMALFMRTELAVPGLQFLSNEQYNQ
LFTMHGTAMLLFYATPIVFGFANLVLPLQIGAPDVAFPRLNALSFWLFVFGALIALAGFITPSGAADFGWTAYTPLSDAV
HSPGPGGDLWIFGLGVGGLGTILGGVNMITTVVCMRAPGMTMFRMPIFTWNILVTSILVLLIFPLLTAALFALAADRHLG
AHIYDPANGGVLLWQHLFWFFGHPEVYVIALPFFGIVSEIFPVFSRKPIFGYTTLIYATIAIAALSVAVWAHHMFATGAV
LLPFFSFMTFLIAVPTGIKFFNWIGTMWRGQLTFQTPMLFSVGFLLTFLLGGLSGVLLASPPLDFHVTDSYFVIAHFHYV
LFGTIVFATYAGIYFWFPKMTGRLLDEKLGKLHFWLTFIGFHTTFLVQHWVGDEGMPRRYADYLPSDGFTTLNIVSTIGA
FILGISTLPFLWNIFRSWRYGEPVVVDDPWGHGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHMVERMRAEAHIG
RHATAGEIQEGYGPRTEPDRS

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=513, Percent_Identity=41.7153996101365, Blast_Score=369, Evalue=1e-102,
Organism=Escherichia coli, GI1786634, Length=555, Percent_Identity=42.5225225225225, Blast_Score=417, Evalue=1e-118,
Organism=Saccharomyces cerevisiae, GI6226519, Length=538, Percent_Identity=37.360594795539, Blast_Score=354, Evalue=3e-98,
Organism=Saccharomyces cerevisiae, GI6226524, Length=318, Percent_Identity=40.251572327044, Blast_Score=234, Evalue=2e-62,
Organism=Saccharomyces cerevisiae, GI6226523, Length=253, Percent_Identity=35.5731225296443, Blast_Score=150, Evalue=8e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 64876; Mature: 64745

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTESVVQPTLTARRPFPERLGPKGNLIYKVITTTDHKLIGIMYCVACFAFFLVGGLMAL
CCCCHHHCCHHHCCCCCHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
FMRTELAVPGLQFLSNEQYNQLFTMHGTAMLLFYATPIVFGFANLVLPLQIGAPDVAFPR
HHHHHHCCCCHHHHCCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCH
LNALSFWLFVFGALIALAGFITPSGAADFGWTAYTPLSDAVHSPGPGGDLWIFGLGVGGL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCCEEEEEECCCHH
GTILGGVNMITTVVCMRAPGMTMFRMPIFTWNILVTSILVLLIFPLLTAALFALAADRHL
HHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GAHIYDPANGGVLLWQHLFWFFGHPEVYVIALPFFGIVSEIFPVFSRKPIFGYTTLIYAT
CCEEECCCCCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCCCHHHHHHHHH
IAIAALSVAVWAHHMFATGAVLLPFFSFMTFLIAVPTGIKFFNWIGTMWRGQLTFQTPML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEECCHHH
FSVGFLLTFLLGGLSGVLLASPPLDFHVTDSYFVIAHFHYVLFGTIVFATYAGIYFWFPK
HHHHHHHHHHHHCCCCCEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTGRLLDEKLGKLHFWLTFIGFHTTFLVQHWVGDEGMPRRYADYLPSDGFTTLNIVSTIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCHHHHHHHHHH
AFILGISTLPFLWNIFRSWRYGEPVVVDDPWGHGNSLEWATSCPPPRHNFTELPRIRSER
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCC
PAFELHYPHMVERMRAEAHIGRHATAGEIQEGYGPRTEPDRS
CCEEECCHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TTESVVQPTLTARRPFPERLGPKGNLIYKVITTTDHKLIGIMYCVACFAFFLVGGLMAL
CCCHHHCCHHHCCCCCHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
FMRTELAVPGLQFLSNEQYNQLFTMHGTAMLLFYATPIVFGFANLVLPLQIGAPDVAFPR
HHHHHHCCCCHHHHCCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCH
LNALSFWLFVFGALIALAGFITPSGAADFGWTAYTPLSDAVHSPGPGGDLWIFGLGVGGL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCCEEEEEECCCHH
GTILGGVNMITTVVCMRAPGMTMFRMPIFTWNILVTSILVLLIFPLLTAALFALAADRHL
HHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GAHIYDPANGGVLLWQHLFWFFGHPEVYVIALPFFGIVSEIFPVFSRKPIFGYTTLIYAT
CCEEECCCCCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCCCHHHHHHHHH
IAIAALSVAVWAHHMFATGAVLLPFFSFMTFLIAVPTGIKFFNWIGTMWRGQLTFQTPML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEECCHHH
FSVGFLLTFLLGGLSGVLLASPPLDFHVTDSYFVIAHFHYVLFGTIVFATYAGIYFWFPK
HHHHHHHHHHHHCCCCCEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTGRLLDEKLGKLHFWLTFIGFHTTFLVQHWVGDEGMPRRYADYLPSDGFTTLNIVSTIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCHHHHHHHHHH
AFILGISTLPFLWNIFRSWRYGEPVVVDDPWGHGNSLEWATSCPPPRHNFTELPRIRSER
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCC
PAFELHYPHMVERMRAEAHIGRHATAGEIQEGYGPRTEPDRS
CCEEECCHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]