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The map label for this gene is idsA [H]

Identifier: 119869363

GI number: 119869363

Start: 3493984

End: 3495063

Strand: Direct

Name: idsA [H]

Synonym: Mkms_3331

Alternate gene names: 119869363

Gene position: 3493984-3495063 (Clockwise)

Preceding gene: 119869362

Following gene: 119869364

Centisome position: 60.9

GC content: 71.76

Gene sequence:

>1080_bases
GTGGATGCCGCGGCTCCGTCAGCCGCCGAGTTGGCCGGAGCCGTCACCGAGCAGTTGCGGGACTACCTGTCCGCGCGCCG
GCGCGATGCCGCCTACATCGGTTCCGACTACGCGGAGCTGACCGCCGCACTCGAGGAGTTCGTGCTCCGGGGCGGTAAAC
GCCTCCGGCCGGCCTTCGCGTACTGGGGCTGGCGGGCGGTGGCCGACCGGCCCGCCGACAGCGGTGTCCTGCTGCTGTTC
TCCGCGCTGGAACTGCTGCACGCCTGCGCACTGGTGCACGACGACGTGATCGACGCCTCGGCGACGCGCCGCGGGTTGCC
GACCGTGCACCGGCTGTTCGCCGACCGCCACGCCGACCGGGGTTGGCACGGTTCGTCCGAACAGTTCGGCCTGTCGGCGG
CGATCCTGGCCGGCGACCTGTCGCTGGTGTGGGCCGACGACATCGTCGCCTCGGTCGATCTGCCCCTCGACGCCCACCGC
CGCGTGCAGCGGGTGTGGGCCGACATCCGGACCGAGGTGCTCGGCGGGCAGTTCCTCGACATCGCCGCCGAAGCGAGCGG
AGCCCAGACGGTCGCGTCGGCGATGACGGTGAACACCTACAAGACCGCCTCGTACACGGTGTCGCGGCCGCTGCAGCTCG
GTGCGGCCGCGGCCGCCGACCGCCCCGAGGTGCTGGAGATCTTCCACCAGCTCGGCACCGACATCGGGGTGGCGTTCCAA
CTGCGCGACGACGTCCTCGGCGTGTTCGGGGATCCGGCCGTCACGGGCAAACCCTCCGGAGACGACCTGCGGTCGGGTAA
GCGCACCGTGCTGCTGGCCGAGGCCGTCGAACTCGCCGAGAAGACCGATCAGGGCACCGCCGCGCTGCTGCGCTCGTCGA
TCGGCACCGATCTGAGCGAGTCGCAGGTGCGCGAACTGTGTTCGGCCATCGAGTCGGTCGGTGCGCTCACGGCGGTCGAG
GAACGCATCGCGCTGCTGACCCGCCGCTCGCTGGAGGCGCTGGACGCCGCACCGATCGACCCGCAGGCCAAGGCCGGCCT
GACCGAACTCGCCAGATTGGCCGCCAACCGGTCCGCCTGA

Upstream 100 bases:

>100_bases
TGGTGGCCGCGATCATCGGCGGTCTGGCCTGGAGCAGCCGGGACCGTTCCCCCACCCTCGCCGACCCCAACCCGAACGAC
GAAAGGGGCACCCGCTGAGC

Downstream 100 bases:

>100_bases
GCATGGTCACACCCACTCCGACCGAGACGCCGAAACCCGGCTCGGCGCAACATGTCTCCCGCCTGATCGCATTCGCCTCG
TCGCCGTCGGGCAGACCCGC

Product: polyprenyl synthetase

Products: NA

Alternate protein names: (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyl pyrophosphate synthase; FPP synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MDAAAPSAAELAGAVTEQLRDYLSARRRDAAYIGSDYAELTAALEEFVLRGGKRLRPAFAYWGWRAVADRPADSGVLLLF
SALELLHACALVHDDVIDASATRRGLPTVHRLFADRHADRGWHGSSEQFGLSAAILAGDLSLVWADDIVASVDLPLDAHR
RVQRVWADIRTEVLGGQFLDIAAEASGAQTVASAMTVNTYKTASYTVSRPLQLGAAAAADRPEVLEIFHQLGTDIGVAFQ
LRDDVLGVFGDPAVTGKPSGDDLRSGKRTVLLAEAVELAEKTDQGTAALLRSSIGTDLSESQVRELCSAIESVGALTAVE
ERIALLTRRSLEALDAAPIDPQAKAGLTELARLAANRSA

Sequences:

>Translated_359_residues
MDAAAPSAAELAGAVTEQLRDYLSARRRDAAYIGSDYAELTAALEEFVLRGGKRLRPAFAYWGWRAVADRPADSGVLLLF
SALELLHACALVHDDVIDASATRRGLPTVHRLFADRHADRGWHGSSEQFGLSAAILAGDLSLVWADDIVASVDLPLDAHR
RVQRVWADIRTEVLGGQFLDIAAEASGAQTVASAMTVNTYKTASYTVSRPLQLGAAAAADRPEVLEIFHQLGTDIGVAFQ
LRDDVLGVFGDPAVTGKPSGDDLRSGKRTVLLAEAVELAEKTDQGTAALLRSSIGTDLSESQVRELCSAIESVGALTAVE
ERIALLTRRSLEALDAAPIDPQAKAGLTELARLAANRSA
>Mature_359_residues
MDAAAPSAAELAGAVTEQLRDYLSARRRDAAYIGSDYAELTAALEEFVLRGGKRLRPAFAYWGWRAVADRPADSGVLLLF
SALELLHACALVHDDVIDASATRRGLPTVHRLFADRHADRGWHGSSEQFGLSAAILAGDLSLVWADDIVASVDLPLDAHR
RVQRVWADIRTEVLGGQFLDIAAEASGAQTVASAMTVNTYKTASYTVSRPLQLGAAAAADRPEVLEIFHQLGTDIGVAFQ
LRDDVLGVFGDPAVTGKPSGDDLRSGKRTVLLAEAVELAEKTDQGTAALLRSSIGTDLSESQVRELCSAIESVGALTAVE
ERIALLTRRSLEALDAAPIDPQAKAGLTELARLAANRSA

Specific function: Unknown

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=183, Percent_Identity=30.6010928961749, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1786623, Length=248, Percent_Identity=31.8548387096774, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789578, Length=310, Percent_Identity=27.4193548387097, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17508563, Length=227, Percent_Identity=29.9559471365639, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17505681, Length=258, Percent_Identity=27.5193798449612, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24651612, Length=252, Percent_Identity=29.3650793650794, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.1; =2.5.1.10 [H]

Molecular weight: Translated: 38162; Mature: 38162

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAAAPSAAELAGAVTEQLRDYLSARRRDAAYIGSDYAELTAALEEFVLRGGKRLRPAFA
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHH
YWGWRAVADRPADSGVLLLFSALELLHACALVHDDVIDASATRRGLPTVHRLFADRHADR
HHCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
GWHGSSEQFGLSAAILAGDLSLVWADDIVASVDLPLDAHRRVQRVWADIRTEVLGGQFLD
CCCCCCCCCCHHHHHHHCCCCEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHH
IAAEASGAQTVASAMTVNTYKTASYTVSRPLQLGAAAAADRPEVLEIFHQLGTDIGVAFQ
HHHHCCCHHHHHHHHHHCCEECCCEECCCCHHHHHHHCCCCHHHHHHHHHHCCCCEEEEE
LRDDVLGVFGDPAVTGKPSGDDLRSGKRTVLLAEAVELAEKTDQGTAALLRSSIGTDLSE
EHHHHHHHCCCCCCCCCCCCCHHHCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHCCCCCH
SQVRELCSAIESVGALTAVEERIALLTRRSLEALDAAPIDPQAKAGLTELARLAANRSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDAAAPSAAELAGAVTEQLRDYLSARRRDAAYIGSDYAELTAALEEFVLRGGKRLRPAFA
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHH
YWGWRAVADRPADSGVLLLFSALELLHACALVHDDVIDASATRRGLPTVHRLFADRHADR
HHCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
GWHGSSEQFGLSAAILAGDLSLVWADDIVASVDLPLDAHRRVQRVWADIRTEVLGGQFLD
CCCCCCCCCCHHHHHHHCCCCEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHH
IAAEASGAQTVASAMTVNTYKTASYTVSRPLQLGAAAAADRPEVLEIFHQLGTDIGVAFQ
HHHHCCCHHHHHHHHHHCCEECCCEECCCCHHHHHHHCCCCHHHHHHHHHHCCCCEEEEE
LRDDVLGVFGDPAVTGKPSGDDLRSGKRTVLLAEAVELAEKTDQGTAALLRSSIGTDLSE
EHHHHHHHCCCCCCCCCCCCCHHHCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHCCCCCH
SQVRELCSAIESVGALTAVEERIALLTRRSLEALDAAPIDPQAKAGLTELARLAANRSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]