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The map label for this gene is dctR [H]

Identifier: 119869333

GI number: 119869333

Start: 3462611

End: 3463273

Strand: Direct

Name: dctR [H]

Synonym: Mkms_3301

Alternate gene names: 119869333

Gene position: 3462611-3463273 (Clockwise)

Preceding gene: 119869332

Following gene: 119869335

Centisome position: 60.35

GC content: 69.08

Gene sequence:

>663_bases
ATGCGTGACGTGCTGGTGGTCGACGACGATTTCATGGTCGCCGACATCCACCGCCGGTTCGTCGAAAGGGTGGACGGGTT
CCGGGCGGTCGGGGTTGCCCGAACGGGCGCTGAAGCACTCACCGCCGCACGGGAACTCGCACCGCACCTGATTCTGCTGG
ACGTCTACCTGCCGGATATGACGGGCCTCGAGGTGCTGCAGCGGTTGCGGTCGGGCGGGGACGGCGTCGGGGTCATCATG
ATCACCGCCGCGCGGGAACTCGACACCGTCCGTGCGGCGCTCGACGGCGGCGCGGCGGACTATCTGATCAAACCGTTCGA
GTTCGCCCAGTTGCGCGCCAAGCTGGAGGCGTTCGCGGCCCGCGCCGACGCCCTGGAATCCGCGACCGGCGCCGATCAGT
CGCTGATCGACTCGCTGTTCGGCCGGCCCAGCGGCAACGAGGTGCTGCCCAAGGGTCTGGGCATCGAGACCGGGCGGCTG
GTCCTCGACGCCGTGCAGCGAGCCGGCGAGGTGTCGGCGACGGAATGCGCTGAGCTGGTGGGCATCTCGCGAGTGAGCGC
ACGCCGCTACCTGGAGCACTATTTGAGTACGGGCGCGTTGGAGTTGCGGTTGCAGTACGGGGCGGGGCGGCCCGAACGGC
GTTACCGGGTCAGCGCGGCATGA

Upstream 100 bases:

>100_bases
CTGGTCACCGCCCAGCACGGCGGCGTGGTGGACGTCTCCGACCGCGCGGACGGTGGCGCAGTGTTCACCGTGCGGTTGCC
GCCCAGCCGGGTGGCAGCGC

Downstream 100 bases:

>100_bases
ACCCGGGCCCGCCGAACGGGCTGACGAACTTGGCGCACGGCCCCAGCAGATCTGGGCGGAAGAACTTGGACGCGATGCAC
TCGCCGTCGACGCCGGGATT

Product: response regulator receiver/unknown domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MRDVLVVDDDFMVADIHRRFVERVDGFRAVGVARTGAEALTAARELAPHLILLDVYLPDMTGLEVLQRLRSGGDGVGVIM
ITAARELDTVRAALDGGAADYLIKPFEFAQLRAKLEAFAARADALESATGADQSLIDSLFGRPSGNEVLPKGLGIETGRL
VLDAVQRAGEVSATECAELVGISRVSARRYLEHYLSTGALELRLQYGAGRPERRYRVSAA

Sequences:

>Translated_220_residues
MRDVLVVDDDFMVADIHRRFVERVDGFRAVGVARTGAEALTAARELAPHLILLDVYLPDMTGLEVLQRLRSGGDGVGVIM
ITAARELDTVRAALDGGAADYLIKPFEFAQLRAKLEAFAARADALESATGADQSLIDSLFGRPSGNEVLPKGLGIETGRL
VLDAVQRAGEVSATECAELVGISRVSARRYLEHYLSTGALELRLQYGAGRPERRYRVSAA
>Mature_220_residues
MRDVLVVDDDFMVADIHRRFVERVDGFRAVGVARTGAEALTAARELAPHLILLDVYLPDMTGLEVLQRLRSGGDGVGVIM
ITAARELDTVRAALDGGAADYLIKPFEFAQLRAKLEAFAARADALESATGADQSLIDSLFGRPSGNEVLPKGLGIETGRL
VLDAVQRAGEVSATECAELVGISRVSARRYLEHYLSTGALELRLQYGAGRPERRYRVSAA

Specific function: Member of the two-component regulatory system dctS/dctR. Essential for expression of dctP [H]

COG id: COG4565

COG function: function code KT; Response regulator of citrate/malate metabolism

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790566, Length=228, Percent_Identity=36.4035087719298, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1786838, Length=218, Percent_Identity=33.9449541284404, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1790437, Length=129, Percent_Identity=35.6589147286822, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789809, Length=135, Percent_Identity=34.8148148148148, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788550, Length=111, Percent_Identity=35.1351351351351, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1786911, Length=139, Percent_Identity=38.8489208633094, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87082012, Length=79, Percent_Identity=43.0379746835443, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI1786784, Length=76, Percent_Identity=38.1578947368421, Blast_Score=60, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23754; Mature: 23754

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDVLVVDDDFMVADIHRRFVERVDGFRAVGVARTGAEALTAARELAPHLILLDVYLPDM
CCCEEEECCCHHHHHHHHHHHHHHCCHHEEHHHHCCHHHHHHHHHHCCCEEEEEECCCCC
TGLEVLQRLRSGGDGVGVIMITAARELDTVRAALDGGAADYLIKPFEFAQLRAKLEAFAA
CHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHH
RADALESATGADQSLIDSLFGRPSGNEVLPKGLGIETGRLVLDAVQRAGEVSATECAELV
HHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHH
GISRVSARRYLEHYLSTGALELRLQYGAGRPERRYRVSAA
HHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEECCC
>Mature Secondary Structure
MRDVLVVDDDFMVADIHRRFVERVDGFRAVGVARTGAEALTAARELAPHLILLDVYLPDM
CCCEEEECCCHHHHHHHHHHHHHHCCHHEEHHHHCCHHHHHHHHHHCCCEEEEEECCCCC
TGLEVLQRLRSGGDGVGVIMITAARELDTVRAALDGGAADYLIKPFEFAQLRAKLEAFAA
CHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHH
RADALESATGADQSLIDSLFGRPSGNEVLPKGLGIETGRLVLDAVQRAGEVSATECAELV
HHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHH
GISRVSARRYLEHYLSTGALELRLQYGAGRPERRYRVSAA
HHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA