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The map label for this gene is fadE12 [H]

Identifier: 119869297

GI number: 119869297

Start: 3424760

End: 3425914

Strand: Direct

Name: fadE12 [H]

Synonym: Mkms_3265

Alternate gene names: 119869297

Gene position: 3424760-3425914 (Clockwise)

Preceding gene: 119869296

Following gene: 119869298

Centisome position: 59.69

GC content: 65.11

Gene sequence:

>1155_bases
ATGGAATTGCACGAGACAGAGGAACGTCAGGACCTGCGCAAGGCGGTCGCCGAGATCGCCAAGGACTTCGGACACGAGTA
CTACCTGGAAAAGTCGCTGGCCGGCGGGAAGAGCACCGAGCTGTGGCAGGCCGTGGGCAAACAGGGCTTCCTCGGGGTGA
ACCTTTCCGAGCAGTACGGCGGCGGCGGCGGCGGCATCTACGACATGCAGATCGTCGGTGAGGAGCTCGCCGCGGCGGGC
TGCCCGCTGCTGATGACCGTCGTCTCGCCGACCATCTGCGGCACGATCATCCAGGCATTCGGCAGTGAGGAACTCAAGCA
GCAGTGGCTGCCGGGCATCGCCAGCGGCGAGACGATCATGGCATTCGCGATCACCGAGCCGGACGCGGGCTCGAACTCGC
ACAACATCTCCACGACCGCGAAACGCGACGGCGACGACTGGGTCATCAACGGCACCAAGTACTACATTTCTGGTGTCGAC
GAAGCCGAAGCGATCCTGGTCGTCACCCGAACGTCTACCAACGACAGTGGTCGCGGACTACTCAGCTTGCTCGTCGTGCC
CACCGATGTCCCCGGGCTCACCAAGTCACTCATCCCGGTGCAGGCGGTCACTCCAGAGAAGCAGTTCACTCTATTCTTCG
ATGACGTCCGCGTGCCGGCCGCCAACCTTATCGGCGCGGAGAACGAGGGCCTGCGCCAGGTCTTCATGGGCCTGAACCCG
GAGCGAATCATGGGGGCGGCGCTCGGCAACGGCATCGGTCGCTACGCGCTGGATAAAGCCGCCGATTACGCCCGCAACCG
CCACGTGTGGGGAACGCCGATCGGCTCGCACCAAGGCGTATCGCACCCGCTCGCCCACGCCAAGATCCAGGTTGAGCTGG
CCCGGTTGATGACTCAGCGTGCCGCCTCCCTGCACGACGCCGGCGATCCGGGGTCGGGTGAGGCGTCGAACATGGCGAAA
TATGCCGCAGCCGAGGCGGGCATCCTGGCGCTCGACCAGGCGATTCAAACCCACGGCGGCAACGGCATGGCCACCGAGTA
CGGCCTCGCCACGTTGTGGGGTCCGGCCCGGCTCATGCGCACCGCGCCGATCAGCCGCGAAATGATCCTCAACTTCGTGG
CGCAGCACAGCCTGAAACTGCCCGCGTCCTACTGA

Upstream 100 bases:

>100_bases
GGCGGTGGACGGCGGTGAAGTGGCGTCGGACGCCACGGAGCTCTAATGAAGCCGGCGCGCTCCCGATCGGTGGCGCGTCG
ATACCGATGTGAGGAGTGTC

Downstream 100 bases:

>100_bases
GTCGCCGCGGAATGAAAGGGAATCGAATGCAACTCGGCATCGGTCAGTGGGTGAGCCGGCGCGCCTTCCTCAACGGCGGG
CGCACCGCGTTGATCAGCAA

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MELHETEERQDLRKAVAEIAKDFGHEYYLEKSLAGGKSTELWQAVGKQGFLGVNLSEQYGGGGGGIYDMQIVGEELAAAG
CPLLMTVVSPTICGTIIQAFGSEELKQQWLPGIASGETIMAFAITEPDAGSNSHNISTTAKRDGDDWVINGTKYYISGVD
EAEAILVVTRTSTNDSGRGLLSLLVVPTDVPGLTKSLIPVQAVTPEKQFTLFFDDVRVPAANLIGAENEGLRQVFMGLNP
ERIMGAALGNGIGRYALDKAADYARNRHVWGTPIGSHQGVSHPLAHAKIQVELARLMTQRAASLHDAGDPGSGEASNMAK
YAAAEAGILALDQAIQTHGGNGMATEYGLATLWGPARLMRTAPISREMILNFVAQHSLKLPASY

Sequences:

>Translated_384_residues
MELHETEERQDLRKAVAEIAKDFGHEYYLEKSLAGGKSTELWQAVGKQGFLGVNLSEQYGGGGGGIYDMQIVGEELAAAG
CPLLMTVVSPTICGTIIQAFGSEELKQQWLPGIASGETIMAFAITEPDAGSNSHNISTTAKRDGDDWVINGTKYYISGVD
EAEAILVVTRTSTNDSGRGLLSLLVVPTDVPGLTKSLIPVQAVTPEKQFTLFFDDVRVPAANLIGAENEGLRQVFMGLNP
ERIMGAALGNGIGRYALDKAADYARNRHVWGTPIGSHQGVSHPLAHAKIQVELARLMTQRAASLHDAGDPGSGEASNMAK
YAAAEAGILALDQAIQTHGGNGMATEYGLATLWGPARLMRTAPISREMILNFVAQHSLKLPASY
>Mature_384_residues
MELHETEERQDLRKAVAEIAKDFGHEYYLEKSLAGGKSTELWQAVGKQGFLGVNLSEQYGGGGGGIYDMQIVGEELAAAG
CPLLMTVVSPTICGTIIQAFGSEELKQQWLPGIASGETIMAFAITEPDAGSNSHNISTTAKRDGDDWVINGTKYYISGVD
EAEAILVVTRTSTNDSGRGLLSLLVVPTDVPGLTKSLIPVQAVTPEKQFTLFFDDVRVPAANLIGAENEGLRQVFMGLNP
ERIMGAALGNGIGRYALDKAADYARNRHVWGTPIGSHQGVSHPLAHAKIQVELARLMTQRAASLHDAGDPGSGEASNMAK
YAAAEAGILALDQAIQTHGGNGMATEYGLATLWGPARLMRTAPISREMILNFVAQHSLKLPASY

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=370, Percent_Identity=31.8918918918919, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI4557233, Length=341, Percent_Identity=34.8973607038123, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI4501859, Length=341, Percent_Identity=31.6715542521994, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI226958412, Length=363, Percent_Identity=28.3746556473829, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI226958414, Length=326, Percent_Identity=28.8343558282209, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI7656849, Length=382, Percent_Identity=28.2722513089005, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI38505218, Length=294, Percent_Identity=32.9931972789116, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI4557231, Length=365, Percent_Identity=29.3150684931507, Blast_Score=138, Evalue=7e-33,
Organism=Homo sapiens, GI187960098, Length=365, Percent_Identity=29.3150684931507, Blast_Score=138, Evalue=8e-33,
Organism=Homo sapiens, GI48976061, Length=317, Percent_Identity=28.7066246056782, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI211971008, Length=317, Percent_Identity=28.7066246056782, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI76496475, Length=353, Percent_Identity=28.0453257790368, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI4557235, Length=353, Percent_Identity=28.0453257790368, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI21361497, Length=390, Percent_Identity=23.8461538461538, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI7669494, Length=322, Percent_Identity=27.9503105590062, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI4503943, Length=322, Percent_Identity=27.9503105590062, Blast_Score=82, Evalue=7e-16,
Organism=Escherichia coli, GI87081958, Length=383, Percent_Identity=26.6318537859008, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786223, Length=380, Percent_Identity=25.2631578947368, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI87081702, Length=361, Percent_Identity=24.3767313019391, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17570075, Length=371, Percent_Identity=32.8840970350404, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17534899, Length=376, Percent_Identity=31.6489361702128, Blast_Score=167, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI17569725, Length=395, Percent_Identity=29.3670886075949, Blast_Score=150, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI17508101, Length=333, Percent_Identity=28.5285285285285, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17506239, Length=375, Percent_Identity=28, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17538396, Length=327, Percent_Identity=30.2752293577982, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17505929, Length=337, Percent_Identity=29.080118694362, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71990804, Length=285, Percent_Identity=30.1754385964912, Blast_Score=128, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17533517, Length=371, Percent_Identity=25.3369272237197, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17551932, Length=338, Percent_Identity=27.810650887574, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17562446, Length=277, Percent_Identity=29.6028880866426, Blast_Score=104, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI32563615, Length=226, Percent_Identity=29.646017699115, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71985184, Length=282, Percent_Identity=26.5957446808511, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71982178, Length=274, Percent_Identity=24.8175182481752, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17534353, Length=309, Percent_Identity=27.5080906148867, Blast_Score=88, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI71985192, Length=194, Percent_Identity=27.319587628866, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24646207, Length=337, Percent_Identity=33.2344213649852, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI21356377, Length=381, Percent_Identity=31.2335958005249, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24666513, Length=361, Percent_Identity=29.9168975069252, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI21355753, Length=382, Percent_Identity=29.8429319371728, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24660351, Length=366, Percent_Identity=31.6939890710383, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI281363737, Length=366, Percent_Identity=26.775956284153, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI19920834, Length=331, Percent_Identity=27.7945619335347, Blast_Score=76, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 40904; Mature: 40904

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELHETEERQDLRKAVAEIAKDFGHEYYLEKSLAGGKSTELWQAVGKQGFLGVNLSEQYG
CCCCCHHHHHHHHHHHHHHHHHCCHHEEHHHHHCCCCCHHHHHHHCCCCEEECCCHHHCC
GGGGGIYDMQIVGEELAAAGCPLLMTVVSPTICGTIIQAFGSEELKQQWLPGIASGETIM
CCCCCEEEHEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEE
AFAITEPDAGSNSHNISTTAKRDGDDWVINGTKYYISGVDEAEAILVVTRTSTNDSGRGL
EEEEECCCCCCCCCCCCCCCCCCCCCEEECCEEEEEECCCCCCEEEEEEECCCCCCCCCE
LSLLVVPTDVPGLTKSLIPVQAVTPEKQFTLFFDDVRVPAANLIGAENEGLRQVFMGLNP
EEEEEECCCCCCCHHHCCCEEEECCCCEEEEEEECCCCCHHHHCCCCCHHHHHHHHCCCH
ERIMGAALGNGIGRYALDKAADYARNRHVWGTPIGSHQGVSHPLAHAKIQVELARLMTQR
HHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
AASLHDAGDPGSGEASNMAKYAAAEAGILALDQAIQTHGGNGMATEYGLATLWGPARLMR
HHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHCCHHHHCCHHHHHH
TAPISREMILNFVAQHSLKLPASY
CCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MELHETEERQDLRKAVAEIAKDFGHEYYLEKSLAGGKSTELWQAVGKQGFLGVNLSEQYG
CCCCCHHHHHHHHHHHHHHHHHCCHHEEHHHHHCCCCCHHHHHHHCCCCEEECCCHHHCC
GGGGGIYDMQIVGEELAAAGCPLLMTVVSPTICGTIIQAFGSEELKQQWLPGIASGETIM
CCCCCEEEHEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEE
AFAITEPDAGSNSHNISTTAKRDGDDWVINGTKYYISGVDEAEAILVVTRTSTNDSGRGL
EEEEECCCCCCCCCCCCCCCCCCCCCEEECCEEEEEECCCCCCEEEEEEECCCCCCCCCE
LSLLVVPTDVPGLTKSLIPVQAVTPEKQFTLFFDDVRVPAANLIGAENEGLRQVFMGLNP
EEEEEECCCCCCCHHHCCCEEEECCCCEEEEEEECCCCCHHHHCCCCCHHHHHHHHCCCH
ERIMGAALGNGIGRYALDKAADYARNRHVWGTPIGSHQGVSHPLAHAKIQVELARLMTQR
HHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
AASLHDAGDPGSGEASNMAKYAAAEAGILALDQAIQTHGGNGMATEYGLATLWGPARLMR
HHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHCCHHHHCCHHHHHH
TAPISREMILNFVAQHSLKLPASY
CCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]