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The map label for this gene is intR [C]

Identifier: 119869100

GI number: 119869100

Start: 3211232

End: 3212455

Strand: Reverse

Name: intR [C]

Synonym: Mkms_3068

Alternate gene names: 119869100

Gene position: 3212455-3211232 (Counterclockwise)

Preceding gene: 119869112

Following gene: 119869099

Centisome position: 55.99

GC content: 63.56

Gene sequence:

>1224_bases
ATGAAACGGAATCGTAGGGCCAGCGTCGAGGACCGCTGGACCAAGACGGTCCACGATTCGGACGGCAACGCCAAGACCCT
GCCGAGCGCCAACCACGGCAAGGGCAGCCGGTGGCGGGCCAGGTATGTCGATGACCAAGGCCGCGAGCACGCGAGGGGGT
TCTCCCGGAAGGTTGACGCACAGGCGTGGTTGAACGGTCAGGTCAGCGACCAAGTGACAGGAACGTGGACCGACCCCAAG
CTGTCCGGCGTGACGTTCGGCGTCATCGCGGAACGGTGGATACAGACGAAGGCCACTAGGGCACCTAAGACGGTCGCCGG
GTACCGCTCTCTACTGGACGTGGTTGTGTTGCCGCGCTGGCGCGACGTGCCGCTGCGAGACGTGTCATTCGAGGACTTGC
AGCAGTGGGTGAGCGGCTTGTCGGTGAACGGGTCCACTCGCTTCGAGGGCAGGGGTTTGAGCCCGTCGCGGGTAATACAG
GCGCACCAGGTCGTCAGCCAGGTGCTTCGGTACGCGGTGAAGGCGAAGCACCTGCCGGCGAATCCGGCTGACGGTATCGA
ACTCCCGCGCAAGCCCGAGGTAGAGCAGCGATATCTGACTCACGAGCAATTGCAGCGTTTGGCGGTAGCCTCCGGTCGAT
TTCGAACCTTCGTACTCGTCCTCGGGTACTGCGGACTGCGGTTCGGGGAAGCTGCGGCCTTGCGGGTCGGTGATGTGAAC
CTGTCTAGCCGACGCATCCGTATTCGTCGCTCCGTGACCGCGGTGACCGGTCAAGGTCTGGTTGAGGGGCCGACTAAGAA
TCACAGCGCGCGCACGGTGCCGGTACCCAAATTCCTCGCGCCGCTCATCGAGACCGAGGTGGGCGGACGGGTCGACGACG
AGTTGCTGTTCCCGTCGAGGCGGGGCGGCTACCTGACGGAGGGGGAGGTTCGCTGGGTATTCGACGCTGCGGCAGTGGCA
GTCGGGGTGACAGGGTTGACACCGCACGAGCTTCGTCATACGTGCGCAAGCCTGGCGATTGCTGCCGGGGCCAACGTGAA
GGTGTTGCAGACGCTCCTAGGTCATAAGACAGCGATGTTGACGCTGGACCGTTACGGACACCTTTTCCCGGATGATCTTG
GCCGGATTGCGGACGCGTTCGACGATGCCGCTGGATTCACTGCGGACGGTCTGCGGACGGTTGCCATGCTCAAAGCTGTT
CCCGAAGCCGGGAATAGCACTTGA

Upstream 100 bases:

>100_bases
CCAGAGGCGACCGTCAGGCTTCGCGACTCGGTGGTTGAGAGGGCAGCGAACGAGAAACTGCTGAAATTCATGCAGGAGAT
GCAGGAGAAAGGCGCGGTCG

Downstream 100 bases:

>100_bases
CCTGCGTTTGCTGGTGCCCTCGGTGAGATTCGAACTCACACTGTACGGGTTTTGAATCCGTTTCCTCTGCCAGTTGGGAT
ACGAGGGCCTGCGGTGTTCC

Product: phage integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MKRNRRASVEDRWTKTVHDSDGNAKTLPSANHGKGSRWRARYVDDQGREHARGFSRKVDAQAWLNGQVSDQVTGTWTDPK
LSGVTFGVIAERWIQTKATRAPKTVAGYRSLLDVVVLPRWRDVPLRDVSFEDLQQWVSGLSVNGSTRFEGRGLSPSRVIQ
AHQVVSQVLRYAVKAKHLPANPADGIELPRKPEVEQRYLTHEQLQRLAVASGRFRTFVLVLGYCGLRFGEAAALRVGDVN
LSSRRIRIRRSVTAVTGQGLVEGPTKNHSARTVPVPKFLAPLIETEVGGRVDDELLFPSRRGGYLTEGEVRWVFDAAAVA
VGVTGLTPHELRHTCASLAIAAGANVKVLQTLLGHKTAMLTLDRYGHLFPDDLGRIADAFDDAAGFTADGLRTVAMLKAV
PEAGNST

Sequences:

>Translated_407_residues
MKRNRRASVEDRWTKTVHDSDGNAKTLPSANHGKGSRWRARYVDDQGREHARGFSRKVDAQAWLNGQVSDQVTGTWTDPK
LSGVTFGVIAERWIQTKATRAPKTVAGYRSLLDVVVLPRWRDVPLRDVSFEDLQQWVSGLSVNGSTRFEGRGLSPSRVIQ
AHQVVSQVLRYAVKAKHLPANPADGIELPRKPEVEQRYLTHEQLQRLAVASGRFRTFVLVLGYCGLRFGEAAALRVGDVN
LSSRRIRIRRSVTAVTGQGLVEGPTKNHSARTVPVPKFLAPLIETEVGGRVDDELLFPSRRGGYLTEGEVRWVFDAAAVA
VGVTGLTPHELRHTCASLAIAAGANVKVLQTLLGHKTAMLTLDRYGHLFPDDLGRIADAFDDAAGFTADGLRTVAMLKAV
PEAGNST
>Mature_407_residues
MKRNRRASVEDRWTKTVHDSDGNAKTLPSANHGKGSRWRARYVDDQGREHARGFSRKVDAQAWLNGQVSDQVTGTWTDPK
LSGVTFGVIAERWIQTKATRAPKTVAGYRSLLDVVVLPRWRDVPLRDVSFEDLQQWVSGLSVNGSTRFEGRGLSPSRVIQ
AHQVVSQVLRYAVKAKHLPANPADGIELPRKPEVEQRYLTHEQLQRLAVASGRFRTFVLVLGYCGLRFGEAAALRVGDVN
LSSRRIRIRRSVTAVTGQGLVEGPTKNHSARTVPVPKFLAPLIETEVGGRVDDELLFPSRRGGYLTEGEVRWVFDAAAVA
VGVTGLTPHELRHTCASLAIAAGANVKVLQTLLGHKTAMLTLDRYGHLFPDDLGRIADAFDDAAGFTADGLRTVAMLKAV
PEAGNST

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=297, Percent_Identity=26.5993265993266, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 44648; Mature: 44648

Theoretical pI: Translated: 10.60; Mature: 10.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRNRRASVEDRWTKTVHDSDGNAKTLPSANHGKGSRWRARYVDDQGREHARGFSRKVDA
CCCCCCCCHHHHHHHHEECCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCH
QAWLNGQVSDQVTGTWTDPKLSGVTFGVIAERWIQTKATRAPKTVAGYRSLLDVVVLPRW
HHHCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
RDVPLRDVSFEDLQQWVSGLSVNGSTRFEGRGLSPSRVIQAHQVVSQVLRYAVKAKHLPA
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
NPADGIELPRKPEVEQRYLTHEQLQRLAVASGRFRTFVLVLGYCGLRFGEAAALRVGDVN
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEECCCC
LSSRRIRIRRSVTAVTGQGLVEGPTKNHSARTVPVPKFLAPLIETEVGGRVDDELLFPSR
CCCCEEEEHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHCCCCC
RGGYLTEGEVRWVFDAAAVAVGVTGLTPHELRHTCASLAIAAGANVKVLQTLLGHKTAML
CCCCCCCCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEE
TLDRYGHLFPDDLGRIADAFDDAAGFTADGLRTVAMLKAVPEAGNST
EEHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKRNRRASVEDRWTKTVHDSDGNAKTLPSANHGKGSRWRARYVDDQGREHARGFSRKVDA
CCCCCCCCHHHHHHHHEECCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCH
QAWLNGQVSDQVTGTWTDPKLSGVTFGVIAERWIQTKATRAPKTVAGYRSLLDVVVLPRW
HHHCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
RDVPLRDVSFEDLQQWVSGLSVNGSTRFEGRGLSPSRVIQAHQVVSQVLRYAVKAKHLPA
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
NPADGIELPRKPEVEQRYLTHEQLQRLAVASGRFRTFVLVLGYCGLRFGEAAALRVGDVN
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEECCCC
LSSRRIRIRRSVTAVTGQGLVEGPTKNHSARTVPVPKFLAPLIETEVGGRVDDELLFPSR
CCCCEEEEHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHCCCCC
RGGYLTEGEVRWVFDAAAVAVGVTGLTPHELRHTCASLAIAAGANVKVLQTLLGHKTAML
CCCCCCCCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEE
TLDRYGHLFPDDLGRIADAFDDAAGFTADGLRTVAMLKAVPEAGNST
EEHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]